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Hey Volgoat. Yea, so why did af say next weeks hc conference?
Mistake? And no smart-alec comment...hmmmmm.
imo.
porkchop11
Speculation on af's tweet and reason for cancelling conference but looks like the healthcare conf isn't til Nov...
http://www.google.com/#hl=en&sugexp=les%3B&gs_nf=1&gs_mss=credit%20suisse%20healthcareconference%202012&pq=credit%20suisse%20conference%202012&cp=25&gs_id=18&xhr=t&q=credit+suisse+healthcare+conference+2012&pf=p&sclient=psy-ab&oq=credit+suisse+healthcare+conference+2012&gs_l=&pbx=1&bav=on.2,or.r_gc.r_pw.&fp=9e02cebcbf39ac2b&biw=1600&bih=754
Bought some more :0
porkchop11
Why did af say "next weeks" as in not this friday's conference?
Playing games? Doubt it.
imo.
porkchop11
Thanks guys, was wondering if she was halted!
Is this a sign to buy now or what?
good luck!
imo.
porkchop11
No AH? http://www.nasdaq.com/symbol/pphm/after-hours
That's uncommon : 0
imo.
porkchop11
Thanks PG! I'm like Horselover tho, don't twitter or facebook...I'd probably get in too much trouble and would rather stay incognito. Well, maybe if I get too much time on my hands after PPHM blasts off : 0
Let's go PPHM! And I've got your back when I can on BV Board, etc.
Porkchop11
Yea nj all my life too.
Hoax? Nah, cant fake livin longer...
Ok off to watch game.
Imo.
Gl all!
Porkchop11
PG is that you on twitter? Happy 50th if so!
porkchop11
Thanks Pace; looking like a test of the top soon with a lil conference thrown in for some fuel...
Where in NJ? Burlington County here.
Good luck, I did pull the trigger on a small lot at $5 day of cc so I expect at least a retest of that level.
imo.
porkchop11
But vin, that was the purpose of the study...
Eyebuy, I give him the short answer, he asks for more info, I give him links, he asks for the short answer again...lol.
Vin - I don't have the time to see if any data were actually collected but I'm sure that I've seen mention of bavi attaching to the exposed ps. It makes sense if bavi "covers" ps and it's my understanding that ps is exposed on the particles and mets. This includes enveloped virus' and its micros as well.
I mean how much data do you really expect a small biotech to be able of afford to collect, particularly when testing in multiple indications?
...hiding amongst the billions of dying and dead normal cells.
Wow imo. : 0
porkchop11
tomdavid, are you back from the past or something? Need to get up to date. Thanks : o
all imo.
porkchop11
...increased interest/stockprice for our accumulating partner hopefully too entdoc; can you say downpayment (if they were smart). : 0
Hey, thanks for sharing your knowledge and views too over the years.
all imo
porkchop11
You're welcome Vin, but I'm not going to do the work for you when a simple search yields lots of info on the subject:
http://www.google.com/#hl=en&q=peregrine%2C+microparticles+in+the+blood&oq=peregrine%2C+microparticles+in+the+blood&gs_l=serp.3...7956.11014.0.11201.17.15.0.0.0.2.171.967.13j2.15.0.les%3B..0.0...1c.1.5uvSzI246Go&bav=on.2,or.r_gc.r_pw.&fp=b4b2b9f09580a15a&biw=1360&bih=595
good reading.
imo.
porkchop11
Vin, short answer, yes, as long as it exposes ps bavi will bind to it and alert the immune system; microparticles circulating in the bloodstream and METs : 0
imo.
porkchop11
Loof, what the heck is that there varmint your holding in ur pic? And no, not tessie mae...that horseshoe crab lookalike thing a ma-jig, ewwww : 0
I'll have to look into it, but I was invested in biomara, now onty, when merck kg partnered with the co. Not sure what the upfront was, but "double digit" royalties. Stimuvax,which should report next yr p3 results. Not much of a comparison to bavi tho.
all imo.
porkchop11
Yea, what wookie said! LOL!
Wx, wook was at my house Sunday watching the Beagles (eagles) and forgot to log out of IHUB on my computer. When I saw Notuncools post (thanks Notuncool and EZ, Cloaked, etc for your mssgs and PM) post deleted (I saw it before and it said I'd like to share something with the board) and I almost blew a gasket and quickly posted about it, unfortunatley, still under wook's name, OOOOPs.
I can assure you we are two different people (shoot does this mean I have wookie in me too?) and are, in fact, brothers; kind of like spanky and volgoat...
Good luck all, back to the stye...
all imo.
porkchop11
...and that's just the shorts : O
Glad your back to earth loof!
imo.
porkchop11
wook must be handing with the lil wooks.
out. time for some football 'soon'...
Whoa, almost blew a porkrind there...LOL!
Thanks in advance, that bv board aint worth the electrons, totally closed minded.
Wow, I did see $heff mention us recently; nice!
You seem to have a good "grasp" on pphm so I'm always interested in your thoughts.
Thanks again.
all imo.
porkchop11
I think our partner is running the show now : 0 ("o sh/t")...
So why was Notuncoolish's post deleted? Said he needed to share something with the board. What's up with that?
all imo.
porkchop11
No AA? Just wait til the requests for passionate use start comin in...
dew, you ever hear of the word precedent?
all imo.
porkchop11
Oh, and someone please set vinvin straight on the microparticle question, and mets or whatever. Not only the cancerous ones but viral too.
all imo.
porkchop11
Damn wookie mess'n with my computer...loof is that a side effect of that Kornlicker, seeing wookies?
That was my post under wook's id (still logged in, LOL! from Beagles game yesterday).
Again, I think my bro made the right decision, no need to toot your own horn, particulary with one of owner's of the stock website whose contributing "authors/researchers" have been negative on your lead drug candidate, really without doing enuf dd imo.
Smelled like a set-up to me, and I think a lot of posters here had the same suspicion.
So, atone and jr, where's our next buy point? Well, we know your stance atone.
all imo.
porkchop11
Duh, gotta get my time zones down...
Wow, so we might not open back up til Monday?
porkchop11
12:40 est, 1:40 cst.
C'mon baby! Open at $5!
all imo.
porkchop11
From CJ's recent post on Press Pkg:
Yea I knew that was old news CJ, but thought a little look back would be refreshing (our lil bavi)...and the picture of Dr. Thorpe caught my attention (copy paste didnt' work for pic so you have to click on link).
Good luck.
all imo.
porkchop11
Thanks Terry from SI:
A little more info on a 2011 research grant. UTSW generally delivers.
CPRIT grant funds research for new antibody-based cancer drugs By Debbie Bolles / August 2011
Research is under way at UT Southwestern to develop more effective antibody-based drugs that destroy the blood vessels that nourish tumors, killing cancer without harming healthy tissue.
Dr. E. Sally Ward (center) and her co-investigators Drs. Philip Thorpe (left) and Ralph Mason received a $4.57 million grant from CPRIT.
A $4.57 million grant from the Cancer Prevention and Research Institute of Texas is funding
UT Southwestern’s portion of the project, which is led by Dr. E. Sally Ward, professor of immunology and in the Cancer Immunobiology Center. Co-investigators are Dr. Philip Thorpe, professor of pharmacology in the Harold C. Simmons Comprehensive Cancer Center; Dr. Ralph Mason, professor of radiology; and Dr. Raimund Ober, adjunct professor of immunology at UT Southwestern and professor of electrical engineering at UT Dallas.
Over the next five years, the research team hopes to generate two or three promising cancer drugs that can be taken to clinical trials. This research builds on earlier work by Dr. Thorpe, who discovered bavituximab, a drug of the same type now in clinical trials for cancer treatment.
$4,569,454 to Drs. Elizabeth Ward Ober, Ralph Mason, and Philip Thorpe to develop a new class of therapeutics to treat cancers involving the brain and nervous systems, breast, liver, interhepatic bile duct, lung, bronchs and prostate.
“Antibodies as therapeutics tend to be a lot more site-specific and have many less side effects than chemotherapy drugs,” said Dr. Ward, whose expertise is in protein and antibody engineering.
The Food and Drug Administration has approved more than 20 antibody-based drugs, with about half targeting cancer. Rituxan, the first monoclonal antibody for cancer treatment, was approved in 1997.
http://www.utsouthwestern.edu/newsroom/center-times/year-2011/aug-cprit-grant.html
all imo.
porkchop11
I agree with the old timers on this facebook/tweeting fad, but can someone please tweet af and ask how he liked the slides of the rat scans showing bavi honing in on the tumors. Political science degree...LOL!
I think Steve curbed his enthusiasm for Friday...
Be ready to scoop up some cheapies if the bears come'a knockin!
all imo.
porkchop11
...and don't forget his sidekick PORKCHOP11!
To infinitey...and BEYOND!
Good luck ALL Longs.
all imo.
porkchop11
wook, make sure we stop by the shack and grab a few "jugs" for the trip! Grab a few for loof too : )
Yea right? Makes my head hurt...
So I think we're looking for a p-value of .05 or less.
Any one shed some light on the p and h values? What we're looking for if the <=.05 is incorrect.
imo.
porkchop11 (back to the couch, ugh.)
Here you go Abe...a lil lite reading 4 those nerves...
P-value
Example of a p-value for sample size 1 (the test statistic is the single observed value). The vertical coordinate is probability if the statistic is discrete and in that case we should see a probability histogram rather than a curve. (The curve shown is represented as a probability density function so the label on the vertical axis is misleading.) Data yielding a p-value of .05 means there is only a 5% chance obtaining the observed (or more extreme) result if no real effect exists. [3] This definition is rather counter-intuitive, leading to many misunderstandings and misinterpretations. "Common sense" tells us to judge our hypotheses based on how well they fit observed evidence. This is not what a p-value describes. Instead, it describes the likelihood of observing certain data given that the null hypothesis is true.
From Wikipedia, the free encyclopedia
In statistical hypothesis testing, the p-value is the probability of obtaining a test statistic at least as extreme as the one that was actually observed, assuming that the null hypothesis is true. [1] One often "rejects the null hypothesis" when the p-value is less than the significance level a (Greek alpha), which is often 0.05 or 0.01. When the null hypothesis is rejected, the result is said to be statistically significant.
And read the coin flip test & formula at wi ki site if you really want lol. http://en.wikipedia.org/wiki/P_value
imo
hope everyone's dealing ok with the "weather" today...under-the-weather that is.
porkchop11
Doc, I saw that too...spookey.
Pulled trigger at 2.45, but got it at 2.449; gee thanks TD.
Still say AA is likely; remember "Sickest of the sick".
all imo.
porkchop11
Silly? Gee, if only I had a dollar for everytime you said that...I'd already be a PPHM millionaire.
porkchop11
Not yet, but watching very closely. Core intact but will add more within next week or so.
Still think some "articles" are waiting in the wings.
imo.
porkchop11
Some have been trying to get the short raiders (love it) to address these exact issues but like you said they won't because it goes against their goals.
Where have I heard that Phrase by Tech Writer "Placebo MY ASS"? : )
all imo.
porkchop11
Now that's funny...
All speculation at this point, except for the favorable mos trend.
all imo.
porkchop11
Awesome post RR! Wow!! eom