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Zynerba Pharmaceuticals (ZYNE)

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Last Post: 10/18/2017 10:41:14 AM - Followers: 65 - Board type: Free - Posts Today: 0

Zynerba Pharmaceuticals, Inc. is a specialty pharmaceutical company focused on developing and commercializing synthetic cannabinoid therapeutics formulated for transdermal delivery. The Company is evaluating approximately two product candidates, ZYN002 and ZYN001, in over five indications. The Company intends to study ZYN002 in patients with refractory epilepsy, osteoarthritis and Fragile X syndrome. The Company's ZYN002 is synthetic cannabidiol (CBD) formulated as a permeation-enhanced gel for transdermal delivery. ZYN002 is being developed as a clear that is designed to provide controlled drug delivery with once- or twice-daily dosing. ZYN001 is a pro-drug of tetrahydrocannabinol (THC) that enables transdermal delivery through a patch. The Company intends to test the ZYN001 patch for application to the arm, back and thigh. The Company intends to study ZYN001 in patients with fibromyalgia and peripheral neuropathic pain.

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Corporate Profile

Zynerba (NASDAQ: ZYNE) is pioneering the development of patent-protected, next-generation synthetic cannabinoid therapeutics formulated for transdermal delivery. Its two lead product candidates in development include ZYN002 and ZYN001, which are being evaluated in five indications. ZYN002 is the first and only synthetic cannabidiol (CBD) formulated as a permeation-enhanced gel for transdermal delivery. In June 2016, the company initiated the STAR 1 Phase 2 clinical trial in refractory epilepsy patients and in August 2016, initiated the STOP Phase 2 clinical trial in patients with osteoarthritis of the knee. A Phase 2 clinical trial in patients with Fragile X syndrome will be initiated in the second half of 2016. 

ZYN001, a prodrug of THC that enables transdermal delivery through the skin and circulatory system via a patch, is in preclinical development. A Phase 1 clinical trial is planned in the first half of 2017.

In August 2015, Zynerba completed an initial public offering, raising net proceeds of $42.1 million. As of June 30, 2016, cash and cash equivalents totaled $32.1 million, which is projected to fund five Phase 2 clinical trials through 2017.

Zynerba Pharmaceuticals, Inc., (Nasdaq: ZYNE) announced today the pricing of its initial public offering of 3 million shares of common stock at a public offering price of $14.00 per share, before underwriting discounts. All of the shares in the offering are being sold by Zynerba. In addition, Zynerba has granted the underwriters an option to purchase up to 450,000 additional shares of common stock at the public offering price, less the underwriting discount. Zynerba's common stock has been approved for listing on the NASDAQ Global Market and is expected to begin trading under the symbol "ZYNE" on August 5, 2015.

Jefferies LLC and Piper Jaffray & Co. are acting as joint book-running managers for the offering, and Canaccord Genuity Inc. and Oppenheimer & Co. Inc. are acting as co-managers for the offering. This offering is being made only by means of a prospectus.

Extremely low float:


A table providing the fundamentals of the stock
EPS (TTM) 9/30/2016 | -2.47
P/E Ratio 9/30/2016 | --
Market Cap Micro Cap | 146M
Shares Outstanding 9.95M
Float 7.2M


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ZYNE News: Current Report Filing (8-k) 10/11/2017 08:01:50 AM
ZYNE News: Statement of Changes in Beneficial Ownership (4) 10/03/2017 04:09:06 PM
ZYNE News: Statement of Changes in Beneficial Ownership (4) 10/03/2017 04:08:13 PM
ZYNE News: Statement of Changes in Beneficial Ownership (4) 10/03/2017 04:07:22 PM
ZYNE News: Cannabinoid Biosynthesis Poised as Potential Game-Changer in Drug Development 09/28/2017 08:45:00 AM
#965   Volume is insanely low the last couple of LittleBird 10/18/17 10:41:13 AM
#964   Buy stocky101 10/17/17 03:43:04 PM
#963   But the bounce $12plus tomorrow, it’s a head stocky101 10/17/17 03:42:28 PM
#962   I wish they would hurry up and tell PENNIEStoSTACKS 10/17/17 01:19:45 PM
#961   What are you hearing? Seems a partnership at surfgreen 10/17/17 01:16:27 PM
#960   Not that I'm hearing, but it makes the PENNIEStoSTACKS 10/16/17 03:03:20 PM
#959   Any rumors of a ZYNE agrimed partnership? GREEN MAKER 10/16/17 02:51:36 PM
#958   That article is Junk! The company has 78 Bescaredxx 10/16/17 12:06:17 PM
#957   ZYNE - PENNIEStoSTACKS 10/16/17 08:39:26 AM
#956   Can anyone refer me to where I could LittleBird 10/13/17 09:40:35 PM
#955   These low floaters are heavily manipulated and shorted. surfgreen 10/13/17 04:14:55 PM
#954   Anyone got a happy interpretation of the movement LittleBird 10/13/17 12:01:12 PM
#953   That's a great pdf they released! Updates on LittleBird 10/12/17 02:25:18 PM
#951   Presentation released and posted to their site today: mcjodie 10/11/17 10:04:51 PM
#950   Nice news out taubytaub 10/11/17 08:51:30 AM
#949   A collaboration between Argimed, UNVC and ZYNE, now PENNIEStoSTACKS 10/10/17 08:41:12 PM
#948   Partnership? Also developing treatments for epileptic conditions, with GREEN MAKER 10/10/17 07:48:51 PM
#947   Why would they Merge ? PENNIEStoSTACKS 10/10/17 05:56:46 PM
#946   Thank god for today's rebound. It supports the LittleBird 10/10/17 03:08:25 PM
#945   Nice rebound in progress taubytaub 10/10/17 10:32:16 AM
#944   Ugh, this run down is a drag. I LittleBird 10/09/17 10:24:26 AM
#943   $ZYNE IF THEY MERGE IT WILL BE HUGE idig 10/08/17 01:54:48 PM
#942   UNVC MERGER NEWS may be coming we shall stockchaser64 10/06/17 02:48:05 PM
#940   Bought a starter pack ZNYE good things in Smittytnt 10/06/17 01:28:44 PM
#939   I am with you. 20’s very possible, teens kr8008st 10/06/17 12:28:02 PM
#938   This stock was down in value for so LittleBird 10/06/17 11:44:06 AM
#937   The share structure on the stock is so stocky101 10/06/17 10:57:32 AM
#936   Luv these dips, added another 2000 stocky101 10/06/17 10:11:55 AM
#935   Filling nicely, she’s going to pop stocky101 10/06/17 09:56:58 AM
#934   We have had upgrades across the board on stocky101 10/06/17 09:19:54 AM
#933   $ZYNE I THINK THIS WILL EXPLODE WITH SOME idig 10/06/17 09:17:21 AM
#932   We should be able to add another dollar stocky101 10/06/17 09:01:05 AM
#931   To the moon we go, the best opportunity stocky101 10/06/17 08:59:15 AM
#930   Aye Karamba! :-D Backstabbed 10/05/17 11:24:00 PM
#929   $ZYNE GIVING A PLUG HERE ! COULD BE idig 10/05/17 10:58:30 PM
#928   ZYNE UNVC AGRIMED??? Smittytnt 10/05/17 10:50:00 PM
#927   Posted a reply to that seeking alpha fake Bescaredxx 10/05/17 09:31:55 PM
#926   Let’s move in dollars... Motba 10/05/17 08:36:11 PM
#925   Beautiful aftermarket stocky101 10/05/17 08:10:19 PM
#924   Expecting a BIG bounce here... Motba 10/05/17 04:29:43 PM
#923   $22’s soon stocky101 10/05/17 01:30:52 PM
#922   1500 shares for me, good things coming. kr8008st 10/05/17 12:24:20 PM
#921   Just jumped in with 1,000 shares taubytaub 10/05/17 10:03:04 AM
#920   Upgrade at Roth Capital: LittleBird 10/05/17 08:46:10 AM
#919   All the rise due to new buyers! Just Bescaredxx 10/05/17 08:34:24 AM
#918   Easy double up!$! Gregwit 10/05/17 05:29:12 AM
#917   strong with no volume. No shorting probs. But bobbodom 10/04/17 02:37:44 PM
#916   I feel 13s coming soon. MD-420 10/04/17 02:07:34 AM
#915   $ZYNE$ sweet bounce today surfgreen 10/03/17 07:54:32 PM