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Ongoing sales update:
Best week ever at 21 new retail scripts:
Monthly trend:
8 new scripts, still in a slow and continued uptrend:
Shares of many biotech companies have rallied following the announcement of the Pfizer PFE – Array BioPharma ARRY deal. Announced earlier this week, the deal has an enterprise value of approximately $11.4 billion. The deal is likely to strengthen Pfizer’s oncology portfolio as Array BioPharma is focused on developing targeted small molecule drugs for treating cancer and other high-burden diseases. Its first commercial therapy, Braftovi plus Mektovi, approved as a treatment for BRAF-mutant melanoma, was approved July last year and has shown encouraging uptake. Cancer has become the area of focus of several pharmaceutical companies due to unmet needs and lucrative market opportunities.
https://finance.yahoo.com/news/cancer-gene-therapy-biotechs-focus-152003662.html
Excellent progression on Primo trial. Slide from today's presentation:
Our primary competition for next-generation PI3K delta inhibitors going forward, sales projections:
From 2018
Impatient patients turn to online ‘buyers club’ for new drugs
KEY POINTS
Social Medwork sees its network as filling a gap in the market for the latest drugs against diseases such as cancer, migraine and multiple sclerosis.
In the past 18 months, the group has supplied more than 3,000 patients.
The Dutch group, which charges a fee of around 6 percent, claims to be the only organization focused on newly approved branded drugs.
Frustrated by delays in new medicines reaching their own country, a small but growing number of patients are turning to an online broker that bills itself as a legal version of the Dallas Buyers Club.
While regulators warn of the risk of buying drugs online, the Amsterdam-based Social Medwork sees its network of trusted suppliers as filling a gap in the market for the latest drugs against diseases such as cancer, migraine and multiple sclerosis.
Now it is looking to raise its profile and expand, by signing up former EU Commissioner Neelie Kroes to its supervisory board and securing 1.5 million euros ($1.73 million) in new funding from the Social Impact Ventures capital fund.
Like Ron Woodroof, the 1980s AIDS patient in the movie ‘Dallas Buyers Club’, patients who cannot get the drugs they want through local healthcare systems are using the organization to self-import medicines from abroad.
But while Woodroof had to smuggle drugs across the Mexican border, the Social Medwork’s customers can place orders online legally, as long as they have a prescription and a doctor’s letter stating that the drug is strictly for personal use.
In the past 18 months, the group, which is registered with the Dutch Ministry of Health as a medicines intermediary, has supplied more than 3,000 patients.
They include British migraine sufferer Senty Bera, 43, who recently used the system to buy Aimovig, a new monthly migraine injection from Amgen and Novartis, the first in an improved class of drugs that target a chemical involved in triggering attacks.
“My quality of life was so poor I thought it was worth trying and it is working brilliantly,” Bera said.
As yet, Aimovig is not approved for use within Britain’s state health service - though Bera hopes it will be soon - but its reputation means it is one of Social Medwork’s top-sellers, despite a price tag of 698 euros for two autoinjectors.
A spokeswoman for Britain’s Medicines and Healthcare products Regulatory Agency confirmed there were no formal restrictions on importing such medicines for personal use.
In the past, informal drug-buying networks here have helped supply cheap generic versions of treatments for HIV and hepatitis C. But the Dutch group, which charges a fee of around 6 percent, claims to be the only organization focused on newly approved branded drugs.
With customers in 70 countries, its line-up includes new cancer drugs that are U.S.-approved but not yet available elsewhere, as well as medicines for chronic disorders, such as Roche’s new multiple sclerosis treatment Ocrevus.
Founder Sjaak Vink says the Internet means patients are increasingly aware they may be waiting months or even years for novel drugs following a first approval elsewhere.
“We really need to bridge this gap because this situation is ridiculous,” he said in an interview.
Vink said he was inspired to found the organization by delays in European availability of Merck’s innovative cancer immunotherapy Keytruda.
Today, his group has customers in Australia, the Middle East and Asia, as well as major European markets such as France, Italy, Germany and Britain, where drug delays could worsen if Brexit disrupts supply lines.
Given relatively speedy U.S. approvals, there are currently fewer customers in America, although there was a spike in U.S. demand last year for Mitsubishi Tanabe Pharma’s amyotrophic lateral sclerosis drug Radicut/Radicava, which was approved first in Japan.
https://www.cnbc.com/2018/10/03/impatient-patients-turn-to-online-buyers-club-for-new-drugs.html
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