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Short Vol 2023-05-10 8,496,778 14,636,290 58%
The short sale volume percent (not short interest) for stock ticker TCRX is 58% on May 10, 2023. The short sale volume is 8,496,778. The total volume is 14,636,290.
http://shortvolumes.com/?t=tcrx
TScan Therapeutics, Inc. - 10Q - Quarterly Report - May 10, 2023
https://www.otcmarkets.com/filing/html?id=16638015&guid=kOu-kKnUE8dfJth
"I agree, but we might have to wait for a filing."
Correct, from the 10-Q (March 31/23)
Novartis
In
March 2020,
the Company entered into a Collaboration and License Agreement (the
Novartis Agreement) with Novartis Institutes For Biomedical
Research, Inc. (Novartis) to collaborate on their research efforts
to discover and develop novel TCR-T therapies. At the inception
date of the Novartis Agreement, Novartis or its affiliates held an
ownership interest of more than
10%
in the Company, and at
March 31, 2023,
Novartis held less than
10%
of the common shares outstanding. Under the Novartis Agreement, the
Company will identify and characterize TCRs in accordance with a
research plan and transfer data arising from the research plan.
Novartis will have the option to license and develop TCRs for up to
three novel targets identified in performance of the collaboration
during the collaboration period of the Novartis Agreement. Novartis
will also have rights of first negotiation for certain additional
targets and TCRs identified in performance of the collaboration
during a defined collaboration period of the Novartis Agreement and
for
180 days
after such collaboration period ends (which collaboration period
ended in March 2023). If during such
180-day
right of first negotiation period, the Company notifies Novartis of
the Company’s intent to grant a third party a license to a target
or TCR identified in the collaboration, then Novartis may obtain
the exclusive right to negotiate a license to such target or TCR
for an additional 270 days by providing the Company with a term
sheet to license such target or TCR within 90 days of the Company’s
notice of such intent. The Novartis Agreement provides that the
Company will pay an upfront fee of $20.0
million, research funding totaling $10.0
million and potential milestone payments contingent on clinical,
regulatory and sales success. In addition to payments upon
achievement of certain clinical and regulatory milestones, Novartis
will pay the Company mid-single to low double-digit royalties on
net sales for each product directed to a target licensed by
Novartis. After the end of the collaboration period and the
expiration of Novartis’ first right of negotiation, the Company is
free to develop TCRs against targets not licensed by
Novartis.
The Company concluded that Novartis meets the definition of a
customer, as the Company is delivering research and development
activities and know-how rights. The Company identified performance
obligations for research and development activities, data reporting
and participation in joint steering and research committees. The
Company determined there is a single performance obligation due to
the services being highly interrelated and are therefore not
distinct in the context of the contract. The Company combined the
pre-option research services and data reporting into a single
performance obligation. Novartis has an exclusive option to obtain
a commercial license for up to
three
Targets (as defined in the Novartis Agreement) to pursue further
development and commercialization of the respective Target.
Pursuant to the Novartis Agreement, the option for Novartis to
license, develop, and commercialize Targets is not a performance
obligation at the outset of the Novartis Agreement as it is a
customer option that does not represent a material
right.
The Company looked to the promises in the arrangement to determine
the method of recognition that best coincided with the pattern of
delivery. The Company concluded that the performance of the
research services over the expected research term was the
predominant promise within the performance obligation. The Company
recognized the revenue associated with the performance obligation
using the input method, according to the actual costs incurred as a
percentage of total expected costs to complete the research
services. As costs were incurred, the Company recognized revenue
over time.
The Company determined that the $20.0
million upfront payment, together with the $10.0
million of estimated research costs to be reimbursed by Novartis,
to be the entirety of the consideration to be included in the
transaction price as of the outset of the arrangement. The
potential milestone payments that the Company is eligible to
receive were excluded from the transaction price, as all milestone
amounts were fully constrained based on the assessed probability of
achievement. At this time, the Company has recognized all
consideration in the contract as the performance obligations were
satisfied as of March 31, 2023 and the collaboration period ended.
The Company will continue to assess the probability of milestone
payments throughout the
180-day right of first negotiation period.
The Company recognized $5.8
million and $3.0
million of revenue associated with the Novartis Agreement based on
performance completed during that period for the
three months ended March 31, 2023 and 2022, respectively.
Additionally, the Company incurred $1.9
million and $1.0
million of costs associated with the Novartis Agreement that were
recorded within research and development expenses in the statements
of operations for the
three months ended March 31, 2023 and 2022, respectively. Finally,
as of March 31, 2023,
the Company had
no
deferred revenue as all performance obligations were
satisfied.
The company will host a virtual event on Wednesday, May 17th at 5:30 p.m. ET to discuss highlights from the presentation https://lifescievents.com/event/tscan/
SHORT 2023-05-09 21,279,941 36,487,718 58%
http://shortvolumes.com/?t=tcrx
Incredible accomplishments, enough said. Double digit dollars coming here.
Baker Bros Holdings TSCAN THERAPEUTICS INC
TSCAN THERAPEUTICS INC COM 9,468 UNCH 2,784,792
https://www.nasdaq.com/market-activity/institutional-portfolio/baker-bros-advisors-lp-596248
Baker Brothers’ Philosophy and Strategy
Brothers Julian and Felix Baker have earned their guru status on Wall Street, having delivered an exceptional track record of annualized returns over the years. Julian has a business background from Harvard, while Felix has a Ph.D. in Immunology from Stanford.
Together, they have combined their individual expertise to generate superior returns by focusing solely on the biotech industry. Assets under management grew from $250 million in 2003, to $25.7 billion as of February 15th, 2023.
The fund’s strategy includes utilizing a fundamentally-driven way of investing to come up with its investment decisions, also known as “bottom-up investing”. Unlike top-down investing, which suggests studying the bigger picture of economic factors to make investment decisions, bottom-up investing involves looking at the company-specific fundamentals.
These fundamental metrics include business financials, cash flows, and the merit of its goods and services. This is crucial when investing in the biotech industry, as each company is very unique, requiring niche knowledge to understand its business model.
The fund’s philosophy stands in holding its investments ordinarily for three years, though its higher-conviction investments can be seen held for longer. Additionally, Baker Bros. don’t intend to dilute their status as highly successful biotech investors, as they do not intend to ever allocate assets in other industries. Still, some minor stakes in the industrial sector had been reported in the past.
Finally, the two brothers don’t believe in diversifying the fund’s portfolio. Instead, they emphasize that focusing on specific companies, which they can analyze and understand deeply and place concentrated positions in their securities, can generate superior returns over the long term.
https://www.suredividend.com/baker-brothers/
Yup, this is shaping up for a possible squeeze......
Good Volume
Yup, it is likely going to squeeze big, they want this higher
Yup, it is likely going to squeeze big, they want this higher.
Weird trading like a boxing match
Quote, they have presentation on 17th,
7 Days away
As of yesterday it was higher than 23%, I really don't know, but I was going to compare the chart with LGV*N during that run, decided to skip it. My personal target is 6-8 dollars, it could go higher, I know one thing though, they have presentation on 17th, I also know Baker Brothers is top institutional holding and anything they touch turns into gold. I am sitting pretty with 6000 shares average 3.80, not going anywhere until my target is reached and we will get there, this has the making of a run to 15 dollars in short order.
Also another huge catalyst is waiting on, once they get paid on that first installment from Amgen to the tune of 30 million dollars, it will run, two huge catalyst in a short window, I think those two will push the stock up for a double from here and add in the spice of higher than 23% short positions, it could go for a massive run with volume, that is why I want to compare it with LGV*N at some point to get a better understanding what is actually taking place.
As of yesterday it was higher than 23%, I really don't know, but I was going to compare the chart with LGV*N during that run, decided to skip it. My personal target is 6-8 dollars, it could go higher, I know one thing though, they have presentation on 17th, I also know Baker Brothers is top institutional holding and anything they touch turns into gold. I am sitting pretty with 6000 shares average 3.80, not going anywhere until my target is reached and we will get there, this has the making of a run to 15 dollars in short order.
5% shorted ? Where will it squeeze.
Crazy Horse, brother, I have been watching the pattern on this all morning, ripe for a massive short squeeze, the pattern and tape tells the story, one massive volume will take this thing for a double from here.
Appreciate your input
Sounds even better, now that you are in also. 7-8 is my first target, then 14-15, actually sooner that I thought, 3-4 months.
The idea of TCRX running like LGV*N did just about 2-3 years ago, is definitely not out of the question if we get a ginormous short squeeze.
Sounds even better, now that you are in also. 7-8 is my first target, then 14-15, actually sooner that I thought, 3-4 months.
Baker Brothers is going to take them for a nice ride.
Sounds good
Baker Brothers top institutional investors, they know where this is going in due time, just like they did with every biotech before them, just like MDG*L. 150 million in the bank already and huge back bone from Amgen and Baker Brothers.
Baker Brothers top institutional investors, they know where this is going in due time, just like they did with every biotech before them, just like MDG*L. 150 million in the bank already and huge back bone from Amgen and Baker Brothers.
Price targets 14-15 within the next 6-9 months. Take it for what it is worth, this is not even considering more data coming out mid year till fall.
Not sure if these TIP presentations include any trial data.
An update on the Novartis collaboration would be appropriate, imo, since, if i am not mistaken, that was to end this past March 31/23.
Multi-year partnership with AMGN https://www.prnewswire.com/news-releases/amgen-and-tscan-therapeutics-announce-collaboration-to-identify-novel-targets-in-crohns-disease-301818552.html
Per the terms, TCRX will receive $30M upfront in addition to preclinical, clinical, regulatory, and commercial milestones worth over $500M and tiered single-digit royalties. "TScan's platform provides a best-in-class approach to identify non-conventional drug targets to enable the development of potential first-in-class therapeutics to address unmet medical needs," Raymond Deshaies, AMGN's SVP of Global Research, said.
Baker Brothers, going to annihilate the shorts.
https://stockcharts.com/h-sc/ui?s=TCRX&p=D&yr=0&mn=6&dy=0&id=p38090673899
https://www.barchart.com/stocks/quotes/TCRX/technical-chart?plot=CANDLE&volume=total&data=DO&density=ML&pricesOn=1&asPctChange=0&logscale=0&indicators=ACCUM;SMA(20);SMA(50);SMA(100);SMA(200);CHKMF(20)&sym=SYSX&grid=1&height=210&studyheight=100
https://www.barchart.com/stocks/quotes/TCRX/opinion
Open gap $2.25
TCRX: If this puppy doesn't Close today at circa $20+ per share, well, then it simply ain't a REAL Universe within which we all reside, my Fellow Amerikanoes. (Is it possible to have any BETTER news than what TCRX had today??)
https://www.marketwatch.com/story/tscan-therapeutics-stock-soars-after-amgen-collaboration-on-crohns-disease-treatment-that-could-bring-in-more-than-500-million-5ada4b
https://ca.finance.yahoo.com/news/tscan-therapeutics-announces-upcoming-trial-204200459.html
Not sure if these TIP presentations include any trial data.
An update on the Novartis collaboration would be appropriate, imo, since, if i am not mistaken, that was to end this past March 31/23.
They plan to begin enrolling patients for screening by the middle of the year, with patient dosing expected to commence in Q3. Initial safety and biomarker data for the most advanced single-agent TCRs could be presented by the end of the year, with initial multiplex therapy data for the first combination of TCRs expected in the first half of 2024. Also, will test redosing and explore three-TCR combinations.
In addition, as the programs advance, they intend to introduce additional elements, including features designed to increase the infiltration of TCR-T cells into solid tumours, with the aim of keeping those cells active for a longer time and rendering them more impervious to different immunosuppressive tumour microenvironments.
The solid tumour screening study is up https://www.clinicaltrials.gov/ct2/show/NCT05812027
Upcoming TIP poster https://annualmeeting.asgct.org/program/agenda-details?agendaId=26372
The first patient has been dosed in its PhI umbrella trial. They were treated with TSC-101.
Last at $3.30 - nice close!!
on a blood red market day all over the place.
Thanks Jerome
TCRX: February 2023 Corporate Presentation
https://ir.tscan.com/static-files/1d066354-1ed3-4f4f-b97b-28806d9da9f5
Current Phase 1 clinical trials TSC-100 and TSC-101
https://clinicaltrials.gov/ct2/show/NCT05473910
TCRX........................................https://stockcharts.com/h-sc/ui?s=TCRX&p=W&b=5&g=0&id=p86431144783
Pre-market volume/price ON FIRE!
Are you still here bro?
Interesting development - Thermo Fisher
https://www.precisiononcologynews.com/sequencing/fda-approves-thermo-fisher-hla-typing-test-cdx-immunocore-uveal-melanoma-therapy#.Y5JifLg6BBE
" Dec 07, 2022 | staff reporter
NEW YORK – Thermo Fisher Scientific said on Wednesday that its SeCore CDx HLA Sequencing System was granted de novo classification by the US Food and Drug Administration as a companion diagnostic to Immunocore’s Kimmtrak (tebentafusp-tebn) therapy for uveal melanoma.
Kimmtrak is the only T-cell receptor therapy approved by the FDA for metastatic or unresectable uveal melanoma, a rare but deadly eye cancer, and is indicated for adults who are human leukocyte antigen (HLA)-A*02:01 positive. The marketing authorization makes the SeCore CDx HLA Sequencing System the first and so far only commercially available HLA typing companion diagnostic, Thermo Fisher said.
“Clinicians can now use the SeCore CDx HLA Sequencing System to identify individuals who may benefit from this breakthrough immunotherapy,” Nicole Brockway, Thermo Fisher’s president of transplant diagnostics, said in a statement. “We look forward to continuing to partner with leading-edge companies to develop and commercialize immunotherapies that address unmet needs in a variety of disease areas.”
The interest from TMO bodes well for TCRX, imo. re:Tscan/Receptor scan/safetyscan etc
Both TMO and TCRX recently attended Evercore ISI HealthConx Conference this past November.
Boston Globe Article - TCRX
https://flashalert.me/?symbol=TCRX&source=PR&referer=https://twitter.com/&url=https://www.globenewswire.com/news-release/2022/12/01/2565881/0/en/TScan-Therapeutics-Named-the-Highest-Placed-Midsize-Biotechnology-Company-in-The-Top-Places-to-Work-for-2022-by-The-Boston-Globe.html&s3=TCRX/2022-12-01/08-03-05_000000/glob/6615b141ea2585b5106240ded6167463/TScan-Therapeutics-Named-the-Highest-Placed-Midsize-Biotechnology-Company-in-The-Top-Places-to-Work-for-2022-by-The-Boston-Globe.html
https://news.beeken.io/news-preview?utm_content=newsfeed-Healthcare-TCRX&content=U2FsdGVkX19ZXXYJs7m%2Fupohdh5oJ0uXewj8BZkuLLwyhsIlY6mRHMb13o5JUKk2FpeyrVY7%2BFdDuKOrds7dYYy%2B8ufp%2Btv6FcdPCtcOneQyAo5ox5tVz7rINho02loQ0nlcJI6HuHRoMOvwosGZeNGZ3sOnr7dg7EJqkJC012i2UtNcOljQCYpqb1cQr4wodawTUp05iQKJQVgAS3syKPKjFCUf2WZzRyvtl%2BDXf9HDdvlYUPo%2BX3EhTuMQlmLF2W5tkMwEo%2Fdt7GUH3upBgilTNWYYxq%2BQU%2FGpjfkcwYODGC%2Fg2HPWRBvdtl19R7IsqNifdy69%2B%2FMhfg67h%2F6lPkJBh1KEGg9WOdXxPWb%2FjWMwm2kV29ufi9Evo62mH%2FvHNlTwaEIHaVH%2FIlLgup4wAzDS%2BiztUDyLiFrqOhlYUb3pyLWot4W1CC3n9aiyEdd4xkxmJ%2BvKRkf1TRx6DvO0c8ngNaVGCfiTLg912vCrJC1caocFSwI5CmbOHeDFl%2FyFHp7Nux2K%2Fs1uub3bqs2lkrqCIDen5dhkC6AOAq8RJDxm2nSSMnY3OoiTCbWkGOWdZKqH5jV7LhTfm8yqUDjiLrot7sCDbzCDP8cjT5g3Bu7yAIKW8UF7MKcI%2BKfmC0t7Hy%2BeR9GiQdOz6dmjRsP9iib7MSTCfb4keMAOoSZSTc878glPgB%2BlxdBJ1LtA3ZxDkgtdB8i5nbX09uFzABPp3SSWWnzc%2FzBqQ8ZpnPPHKk0NA82rgDRL2U3WaXIhxto5TPgfryDpC1xE6Lfg9xeqaCh3a0DdNYYhtqMJpbXRzvJMIJZZ7BapyS850JaM2TUoRYpdqLLb2IllabP3Z5xcuKo7NNYfQk%2FnwpcdyDp6dLqEhWBF2Idu7nqMsAweYpMK1VMzfMe7bfWhpUTdeTaHySKgPoHBp2ZlLplybXzP99itA8ediO2rpA20n1ZbJZpp%2BfkXXcpxpr2B6rzuFZGCTkn6jTAAkT%2FdWRK7oED2GbnItYWd6uMPGvrJUfKJIrkt6nbXw8v2xqh70xO6GgDMY913qhCdNS4MraublJHbvxYWhpQ7BPlF2drzly1A0WbxAa9SysHYP%2BmvyZ4I6MW0J%2F%2BULqKY81sO9RA0HNt%2FYLtwFg%2FOx0MlwLNGtd%2BfYH5byrvpmeFYmOnHYb1TreLnfdNtgO3K3w4cOBTcPVH28MBudwnTUvVa9YXKxYI12va1lY6Y8kDoXEl6r0FNvNsI%2BgNB6EvJ0nDwpmlB1kz8Diy4lN0BMO7wsRoPUhsubnKOGQVjUXObStnG2GEeWxNqyyDKnCqQRzeu1vX9LuJM7SLMLyc9jcYlbn4EVjBIFJgMo70mEhOrHKMUgyU4mMQwrITQw7oyToGW1iDt%2BFcECYjNO%2FaKH87shfh4BoG2x%2FBaiiaXTbPBCIoQs9GaP%2Fpc%2FwGZl99lvfq5uf8ppHHskeN9462ZK%2FVus86SYwNQjJXFncQCpG6ryF54T0XgiTRk9er%2BYQtnSydO%2FQq6iPD69BLlYs0BVrcAqPzLBv1ewNF9doCZAL3yTtMq4FD3WcvtM%2FJ4Ms6gebXlKvN5jk34EpVdWaC1GOwIUWOIRK1E%2BRmXmqNqmvsoD5eQM06iNPcaVMiyRuhnfe3BnQtbXsCJLYNucTCz21Y444r8EakSxBBNJzo3IjjNLV4eNPvY4HMoZC67WBtOZM8h7zBTHvOphdRp6k8374ArHSn42W7rAHWDoeA0khcqeGcj9Ig5vlrODGLl0i9I%2BXZ1%2F7ZK8kuNUeAVtV9vnacAMTsjXd139uXzQMSAMOwagLaleZ21aPHeRgLmbaBwuLgfMKiMzRDucF%2F%2FqO7coWUoCuJPLTtI4WWe&utm_source=dlvr.it&utm_medium=twitter
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