JLS Monday, 08/17/15 04:14:40 PM
Re: TREND1 post# 14045
Post # of 14048
Can you say Flozins?
New diabetes drugs -- bypass liver
Been researching that.
"The Arrival of the SGLT2 “Flozins”
Sodium glucose co-transporter-2 (SGLT2) inhibitors are different from most type 2 drugs. Rather than increase insulin production or decrease glucose production, SGLT2s bypass the liver and pancreas and work on the kidneys. In short, the drugs reduce the reabsorption of glucose from the kidneys by making them shunt the glucose into the urinary tract.
The beneficial effects of doing so include negligible risk of hypoglycemia, weight loss, and reduced A1c.
SGLT2 drugs, sometimes referred to as “flozins” because of the last syllables in their name, include canagliflozin (“Invokana,” Johnson & Johnson), dapagliflozin (AstraZeneca and Bristol-Myers Squibb), and empagliflozin (Boehringer Ingelheim and Eli Lilly and Company)."
http://tinyurl.com/py26447
An exhaustive look at diabetes drugs in the pipeline is available at http://tinyurl.com/o626fq2
The PDF, aimed at professionals, is heavy on scientific and medical terminology, but offers useful information to the lay reader.