Home > Boards > US OTC > Biotechs >

Sunshine Biopharma Inc. (SBFM)

Add SBFM Price Alert      Hide Sticky   Hide Intro
Moderator: S-BEES-BUMBLEBEE, Gutinstinct, The Whale, Col317, mrpennystocks, LETSWIN2020
Search This Board: 
Last Post: 9/18/2020 1:54:06 PM - Followers: 636 - Board type: Free - Posts Today: 31






"The Future Of Medicine"



Topoisomerase II is an enzyme that aggressive cancer cells make too much of. When the cell is able to make a lot of the Topoisomerase II 
enzyme, it becomes able to proliferate and metastasize; so, if you can inhibit or destroy the activity of Topoisomerase II, you would then be 
able to prevent cancer cells from spreading. 

Our  Proprietary Technology

Our licensor, Advanomics Corporation, has developed a way to replace the diester bond with a Carbon-Difluoride bond which acts as a perfect diester isostere.  This technology allows us to create a large variety of therapeutic compounds that are completely stable and often more active than the original drugs.  This unique capability allowed us to create our Lead Compound, Adva-27a, an effective and highly specific Topoisomerase II (Top2) Inhibitor. 

Our Carbon-Difluoride Technology is covered by issued and pending patents filed under PCT/FR2003/002330 and PCT/FR2007/000697

Adva-27a is 16-times more effective at killing multidrug resistant  breast cancer cells than Etoposide, the drug currently in use.

Adva-27a is unaffected by P-Glycoprotein, the enzyme responsible for making cancer cells resistant to anti-tumor drugs.

Adva-27a has excellent clearance time (half-life = 54 minutes) as indicated by human microsomes stability studies.

Adva-27a clearance is independent of Cytochrome P450, a mechanism that is less likely to produce toxic intermediates.

Adva-27a is an excellent inhibitor of Topoisomerase ll with an IC50 of only 13.7 micromolar.

Adva-27a has shown excellent pharmacokinetics profile as indicated by studies done in rats

Adva-27a's initial indication will be multidrug resistant breast cancer for which there are little or no treatment options
Our Published Data show that Adva-27a is a true Topoisomerase ll Inhibitor and is significantly more effevtive at killing aggressive cancer cells than Etoposide, the current drug of choice.

Check out SBFM's drug Adva-27a (27a) vs the leading chem drug Etoposide (2) - results are better in every category except two. And in the multi drug resistance breast cancer category (MCF7R) it's over 3x more effective. 

Unique Features of Adva-27a  

* Adva-27a can be taken orally.
* Adva-27a is not a so-called me-too drug; our technology is unique. Adva-27a will be the only Topoisomerase ll Inhibitor on the Market.
* Adva-27a's initial indication will be multi-drug resistant breast cancer. Adva-27a can be used to treat other Top2 Positive Cancer Types (Prostate, Colon, Lung, Stomach, Ovarian).

January 29, 2014 S-4

followed again by another withdrawel

RCMP Canada.

SEC Complaint process

Sunshine Biopharma Inc. Contacts:
Camille Sebaaly, CFO, Tel.: 514-814-0464, Camille.sebaaly@sunshinebiopharma.com
SBFM SEC Filings

Avastin Ousted By FDA For Breast Cancer, Sunshine Biopharma Gears-Up For Clinicals
Chairman and CEO Dr. Steve N. Slilaty Interview 

FDA links:



We were incorporated in the State of Colorado on August 31, 2006 under the name “Mountain West Business Solutions, Inc.”  During our fiscal year ended July 31, 2009 our business was to provide management consulting with regard to accounting, computer and general business issues for small and home-office based companies.  Effective October 15, 2009, we executed an agreement to acquire Sunshine Biopharma, Inc., a Colorado corporation (“SBI”), in exchange for the issuance of 21,962,000 shares of our Common Stock and 850,000 shares of Convertible Preferred Stock, each convertible into twenty (20) shares of our Common Stock (the “Agreement”).  As a result of this transaction our officers and directors resigned their positions with us and were replaced by our current management.  Following completion of this transaction we changed our name to “Sunshine Biopharma, Inc.”.  On December 21, 2011, Advanomics Corporation, a privately held Canadian company (“Advanomics”), and our licensor, exercised its right to convert the 850,000 shares of Series “A” Preferred Stock it held in our Company into 17,000,000 shares of Common Stock.
Intellectual Property
We are the exclusive licensee for the U.S. territory of Advanomics Corporation’s Adva-27a which is covered by international patent applications filed on April 27, 2007 (PCT/FR2007/000697).  These patent applications, which are now issued in Europe and the United States (US 8,236,935) and are still pending elsewhere around the world, were originally owned by Institut National des Sciences Appliquées de Rouen (France) and have recently been purchased by Advanomics Corporation.  On January 14, 2013, Advanomics Corporation filed a new patent application covering Adva-27a manufacturing processes as well as new Adva-27a derivatives and compositions.
Sunshine Biopharma Inc. Contacts:
Camille Sebaaly, CFO, Tel.: 514-814-0464, Camille.sebaaly@sunshinebiopharma.com

SBFM Transfer Agent
Corporate Stock Transfer
3200 Cherry Creek Dr. South
Suite 430
Denver, CO 80209
(303) 282 - 4800 p
(303) 282 -  5800 f


Current Price
Bid Ask Day's Range
  • 1D
  • 1M
  • 2M
  • 3M
  • 6M
  • 1Y
  • 2Y
  • 3Y
  • 5Y
SBFM News: Epazz, Inc. (OTC Pink: EPAZ) - Signs more Healthcare and Government Contracts - Covid-19 Solution 09/17/2020 06:30:00 AM
SBFM News: Traders News Source Issues "Potential Home Run" New Research Report 09/03/2020 09:00:00 AM
SBFM News: Amended Quarterly Report (10-q/a) 08/31/2020 06:01:48 AM
SBFM News: Quarterly Report (10-q) 08/19/2020 01:20:51 PM
SBFM News: Notification That Quarterly Report Will Be Submitted Late (nt 10-q) 08/14/2020 11:18:17 AM
#68565  Sticky Note Must read!! Funding for SBFM Covid treatment Fastmonte 09/16/20 06:57:36 PM
#63725  Sticky Note $SBFM BIG covid-19 play FDA APPROVAL & PATENTS DDMasterStocks 08/11/20 03:27:06 AM
#52464  Sticky Note IMPORTANT READ ON WHY $SBFM IS NEEDED: The Whale 07/15/20 08:50:08 AM
#46492  Sticky Note Meet Dr. Steve Slilaty S-BEES-BUMBLEBEE 06/04/20 06:33:07 AM
#68749   Agreed. The firm would have done extensive DD Nosnibor 09/18/20 01:54:06 PM
#68747   They had to be given some massive positive Fastmonte 09/18/20 12:00:52 PM
#68746   We soon find out why financiers agreed to UP Trend 09/18/20 11:52:49 AM
#68745   Plus SBFM will jump up so fast there timetravelerdos 09/18/20 11:25:32 AM
#68744   That article has more relevance now than it Fastmonte 09/18/20 10:56:22 AM
#68743   As long as 50K slaps on the ask Highlandmike 09/18/20 10:50:48 AM
#68742   Patent gets approved or partnership announced levels this Fastmonte 09/18/20 10:50:27 AM
#68741   let them it’s not like they are making Mrvince 09/18/20 10:35:21 AM
#68740   Organized shorts are stealing weak hands. SBFM is Babubd 09/18/20 10:28:47 AM
#68739   Man, appreciate your enthusiasm and all...but this thing Niceguy1 09/18/20 10:25:24 AM
#68738   Was looking to avg down ..but this thing Niceguy1 09/18/20 10:23:07 AM
#68737   Not as clear cut after all. The Niceguy1 09/18/20 10:18:05 AM
#68736   Yes, time for this to start trending back PokerStar 09/18/20 10:11:28 AM
#68735   Well everybody knows they have a patent otherwise Money Management 09/18/20 10:08:27 AM
#68734   A Dime Baby a Dime+ per share! $SBFM. Babubd 09/18/20 09:53:49 AM
#68733   Looking for a reversal. Volume is low and diablose94 09/18/20 09:52:55 AM
#68732   This is getting beat to death... Larry1955 09/18/20 09:50:20 AM
#68731   Adding more. Happy Friday everyone :) JMMatthews 09/18/20 09:50:08 AM
#68730   SBFM has made many advancements since 2011. Patience moncam 09/18/20 09:39:49 AM
#68729   correct: but even earlier in July 2011 joelahr 09/18/20 09:31:32 AM
#68728   Articles August 4, 2011 moncam 09/18/20 09:21:18 AM
#68727   I couldn't find one. Either way. Fastmonte 09/18/20 09:14:23 AM
#68726   Probably 2018 joelahr 09/18/20 09:02:22 AM
#68725   What was the date of the article? gringojoe 09/18/20 08:58:09 AM
#68724   https://drug-dev.com/sunshine-biopharma-looking-to-mimic-roches-billion-dollar-c Fastmonte 09/18/20 08:28:25 AM
#68723   The Sbfm freight train is loading coal. Fastmonte 09/18/20 08:25:50 AM
#68722   They added this to the website: Antiviral Drugs: We MJP2020 09/18/20 05:19:43 AM
#68721   When you google Sunshine Biopharma this is what MJP2020 09/18/20 05:14:04 AM
#68720   This is the Forest Gump stock...like a box Niceguy1 09/18/20 02:00:55 AM
#68719   So I own shares of a stock that Crash103 09/18/20 12:55:16 AM
#68718   Sars-Cov1 is nicknamed the Swine Flu. Gobsmacked01 09/17/20 11:03:09 PM
#68717   The bid is at 0.02 and the ask BiaseDD 09/17/20 08:36:12 PM
#68716   Friday would be a great day for news...nice Hitoneout 09/17/20 07:59:33 PM
#68715   I agree and believe his cancer drugs could Hitoneout 09/17/20 07:49:59 PM
#68714   “Sunshine on my Shoulders makes me Happy” Hitoneout 09/17/20 07:44:55 PM
#68713   Looked over your stock picks. Leaves a lot of kneester 09/17/20 07:36:38 PM
#68712   Slilaty has been pushing all of his cancer Fastmonte 09/17/20 06:48:01 PM
#68708   Why? joelahr 09/17/20 04:50:46 PM
#68683   on what basis? it's friday. highly doubtful unless tchalla 09/17/20 04:22:19 PM
#68681   Personally I hope when a treatment comes out sorc92 09/17/20 04:18:49 PM
#68680   There is close to 1 million dead worldwide. slider2 09/17/20 04:14:21 PM
#68679   Yea that is how most work in my sorc92 09/17/20 04:11:50 PM
#68678   Covid is now near 200k dead in the bonkerific 09/17/20 04:02:44 PM
#68677   Tomorrow’s gonna be wild folks BiaseDD 09/17/20 03:59:59 PM
#68676   I believe we need something out on the Hawaii life 09/17/20 03:57:10 PM
#68674   Just load and lock her UP. With COVID-19 Babubd 09/17/20 03:47:54 PM
#68671   Yeah..I would like to believe that...but they did Niceguy1 09/17/20 03:39:31 PM
#68670   I totally agree man and I think new diablose94 09/17/20 03:34:03 PM
#68669   Sizable spread indicative of low float JMMatthews 09/17/20 03:33:27 PM
#68664   Exactly right . Real world workers are not sorc92 09/17/20 03:23:43 PM
Consent Preferences