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Sunshine Biopharma Inc. (SBFM)

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Last Post: 3/4/2021 5:12:12 AM - Followers: 702 - Board type: Free - Posts Today: 1

SUNSHINE BIOPHARMA INC
ANTI CANCER DRUGS
ANTI CORONA VIRUS RESEARCH









 

FORM 4 AWARDED TO CEO FOR CONTRIBUTION AND CREATION OF CORONA

VIRUS TREATMENT PATENT. ( 0.10CENT LIQUIDATION VALUE)
 
 
 





 

































"The Future Of Medicine"
 

http://sunshinebiopharma.com

https://mobile.twitter.com/sunshinepharma_

 
Topoisomerase II is an enzyme that aggressive cancer cells make too much of. When the cell is able to make a lot of the Topoisomerase II 
enzyme, it becomes able to proliferate and metastasize; so, if you can inhibit or destroy the activity of Topoisomerase II, you would then be 
able to prevent cancer cells from spreading. 
 

Our  Proprietary Technology

Our licensor, Advanomics Corporation, has developed a way to replace the diester bond with a Carbon-Difluoride bond which acts as a perfect diester isostere.  This technology allows us to create a large variety of therapeutic compounds that are completely stable and often more active than the original drugs.  This unique capability allowed us to create our Lead Compound, Adva-27a, an effective and highly specific Topoisomerase II (Top2) Inhibitor. 
 




Our Carbon-Difluoride Technology is covered by issued and pending patents filed under PCT/FR2003/002330 and PCT/FR2007/000697
 

Adva-27a is 16-times more effective at killing multidrug resistant  breast cancer cells than Etoposide, the drug currently in use.

Adva-27a is unaffected by P-Glycoprotein, the enzyme responsible for making cancer cells resistant to anti-tumor drugs.

Adva-27a has excellent clearance time (half-life = 54 minutes) as indicated by human microsomes stability studies.

Adva-27a clearance is independent of Cytochrome P450, a mechanism that is less likely to produce toxic intermediates.

Adva-27a is an excellent inhibitor of Topoisomerase ll with an IC50 of only 13.7 micromolar.


Adva-27a has shown excellent pharmacokinetics profile as indicated by studies done in rats

Adva-27a's initial indication will be multidrug resistant breast cancer for which there are little or no treatment options
 
 
Our Published Data show that Adva-27a is a true Topoisomerase ll Inhibitor and is significantly more effevtive at killing aggressive cancer cells than Etoposide, the current drug of choice.



Check out SBFM's drug Adva-27a (27a) vs the leading chem drug Etoposide (2) - results are better in every category except two. And in the multi drug resistance breast cancer category (MCF7R) it's over 3x more effective. 


 
Unique Features of Adva-27a  

* Adva-27a can be taken orally.
* Adva-27a is not a so-called me-too drug; our technology is unique. Adva-27a will be the only Topoisomerase ll Inhibitor on the Market.
* Adva-27a's initial indication will be multi-drug resistant breast cancer. Adva-27a can be used to treat other Top2 Positive Cancer Types (Prostate, Colon, Lung, Stomach, Ovarian).
 

January 29, 2014 S-4
https://www.sec.gov/Archives/edgar/data/1402328/000135448814000422/sbfm_s4.htm

followed again by another withdrawel
https://www.sec.gov/Archives/edgar/data/1402328/000135448814002116/sbfm_rw.htm

RCMP Canada.
http://www.rcmp.gc.ca/en
http://www.antifraudcentre-centreantifraude.ca/reportincident-signalerincident/index-eng.htm

SEC Complaint process
https://denebleo.sec.gov/TCRExternal/index.xhtml
================================================================== 
 


http://sunshinebiopharma.com/investor/press-releases/
 
Sunshine Biopharma Inc. Contacts:
Camille Sebaaly, CFO, Tel.: 514-814-0464, Camille.sebaaly@sunshinebiopharma.com
 
SBFM SEC Filings

Avastin Ousted By FDA For Breast Cancer, Sunshine Biopharma Gears-Up For Clinicals
 
Chairman and CEO Dr. Steve N. Slilaty Interview 

FDA links:

http://clinicaltrials.gov/ct2/seac/index

 

 
We were incorporated in the State of Colorado on August 31, 2006 under the name “Mountain West Business Solutions, Inc.”  During our fiscal year ended July 31, 2009 our business was to provide management consulting with regard to accounting, computer and general business issues for small and home-office based companies.  Effective October 15, 2009, we executed an agreement to acquire Sunshine Biopharma, Inc., a Colorado corporation (“SBI”), in exchange for the issuance of 21,962,000 shares of our Common Stock and 850,000 shares of Convertible Preferred Stock, each convertible into twenty (20) shares of our Common Stock (the “Agreement”).  As a result of this transaction our officers and directors resigned their positions with us and were replaced by our current management.  Following completion of this transaction we changed our name to “Sunshine Biopharma, Inc.”.  On December 21, 2011, Advanomics Corporation, a privately held Canadian company (“Advanomics”), and our licensor, exercised its right to convert the 850,000 shares of Series “A” Preferred Stock it held in our Company into 17,000,000 shares of Common Stock.
 
Intellectual Property
 
We are the exclusive licensee for the U.S. territory of Advanomics Corporation’s Adva-27a which is covered by international patent applications filed on April 27, 2007 (PCT/FR2007/000697).  These patent applications, which are now issued in Europe and the United States (US 8,236,935) and are still pending elsewhere around the world, were originally owned by Institut National des Sciences Appliquées de Rouen (France) and have recently been purchased by Advanomics Corporation.  On January 14, 2013, Advanomics Corporation filed a new patent application covering Adva-27a manufacturing processes as well as new Adva-27a derivatives and compositions.
 
Sunshine Biopharma Inc. Contacts:
Camille Sebaaly, CFO, Tel.: 514-814-0464, Camille.sebaaly@sunshinebiopharma.com
 

SBFM Transfer Agent
Corporate Stock Transfer
3200 Cherry Creek Dr. South
Suite 430
Denver, CO 80209
(303) 282 - 4800 p
(303) 282 -  5800 f

http://corporatestock.com

                                                          
https://www.sunshinebiopharma.org/
 
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SBFM News: Statement of Changes in Beneficial Ownership (4) 02/16/2021 12:37:45 PM
SBFM News: Statement of Changes in Beneficial Ownership (4) 02/16/2021 12:34:31 PM
SBFM News: Sunshine Bio launches COVID-19 treatment mice study 02/10/2021 08:48:46 AM
SBFM News: SUNSHINE BIOPHARMA INITIATES COVID-19 TREATMENT MICE STUDY 02/10/2021 08:00:00 AM
SBFM News: CLS Holdings, (OTCQB: CLSH) Record January NET Revenue of $1.48 Million Beating Target 02/09/2021 06:48:48 AM
PostSubject
#83446  Sticky Note International Adva-27a Patent Approved By WIPO Really People 02/14/21 03:25:14 PM
#83382  Sticky Note This vitamin reseller still "curing" cancer?...Junk. Homebrew 02/13/21 09:34:39 PM
#78182  Sticky Note Slapping asks for a reason. SBFM is gonna Babubd 01/26/21 11:01:23 AM
#68565  Sticky Note Must read!! Funding for SBFM Covid treatment Fastmonte 09/16/20 06:57:36 PM
#85824   Nice...It would be awesome if $SBFM could get BlazingStocks 03/04/21 05:12:12 AM
#85823   I saw this as well. That would be GMJDubbs 03/03/21 10:03:06 PM
#85822   who gives a s.... about jim richards shorts Mrvince 03/03/21 10:01:16 PM
#85821   "This funding will support over a hundred projects MJP2020 03/03/21 09:45:00 PM
#85820   Agreed. These type of stocks are not for AAHRR 03/03/21 09:28:25 PM
#85819   Ahhh so you were in here with me sorc92 03/03/21 09:26:32 PM
#85818   HaHaHa! AAHRR 03/03/21 09:20:19 PM
#85817   To "Money Management" If you do not know AAHRR 03/03/21 09:19:11 PM
#85815   Thanks. I am new here. Ihub message board J2themafknroc 03/03/21 08:52:48 PM
#85814   Sorry spellcheck, when it crashes, buy some! jimesica 03/03/21 08:50:39 PM
#85812   It is a crazy wild ride. I jimesica 03/03/21 08:44:59 PM
#85811   Yes it is sorc92 03/03/21 08:38:44 PM
#85810   Yea seen it before. What they don’t realize sorc92 03/03/21 08:37:27 PM
#85809   Long and going longer. It’s almost time Hitoneout 03/03/21 08:22:03 PM
#85808   i think one needs a 6-12 month time PennyWorld 03/03/21 08:13:19 PM
#85807   “I am confused“ EOT 03/03/21 07:56:14 PM
#85806   Are we at $1+ yet? .75 .50 .30 radly 03/03/21 07:32:40 PM
#85804   I hope so! Don'tDrinkTheKoolAid 03/03/21 07:23:06 PM
#85803   Yea, not sure about the site but some MB66 03/03/21 07:16:19 PM
#85802   Good point. I don't use that site. Sounds PennyWorld 03/03/21 07:11:27 PM
#85801   PM Trudeau on Research Funding, Aid for Businesses, MJP2020 03/03/21 07:07:32 PM
#85800   They were shorting and when the stock break Don'tDrinkTheKoolAid 03/03/21 07:01:57 PM
#85799   How about can we hold the teens? Don'tDrinkTheKoolAid 03/03/21 06:55:08 PM
#85798   Yea, I guess that’s why it’s confusing to MB66 03/03/21 06:54:36 PM
#85797   No worries, it will be back above .20 Big Eli 03/03/21 06:50:23 PM
#85796   It never fails, once people get impatient and ALDACON 03/03/21 06:50:10 PM
#85795   5minutes of DD is simply to see what EOT 03/03/21 06:48:43 PM
#85794   The analysis also includes.... Given the current short-term PennyWorld 03/03/21 06:45:04 PM
#85792   How does the tune change so quickly on MB66 03/03/21 06:41:24 PM
#85791   This is an article from yesterday, but they EOT 03/03/21 06:41:09 PM
#85790   Im calling BS on these new posters coming bonkerific 03/03/21 06:39:29 PM
#85789   I'm with you RO. I was really hopeful J2themafknroc 03/03/21 06:31:26 PM
#85788   He works at the car wash down the UHHU 03/03/21 06:27:36 PM
#85787   University of Georgia completely agrees with you. Glad your GMJDubbs 03/03/21 06:20:14 PM
#85786   Ps... I made less then 2% so selling Reluctant Observer 03/03/21 06:18:49 PM
#85785   Who the Hell is Jim Rickards? Money Management 03/03/21 06:17:17 PM
#85783   No possible way I was selling today, and bonkerific 03/03/21 06:16:52 PM
#85781   I believe the company is honestly ran company Money Management 03/03/21 06:14:05 PM
#85780   We all better start paying attention to what UHHU 03/03/21 06:09:07 PM
#85779   Let's look at this pr about RB capital HoldWhatDoor 03/03/21 06:02:30 PM
#85777   LOL... I’ll take that bet. I bet Williams92 03/03/21 05:44:59 PM
#85776   See you in April! Anyone care to bet Reluctant Observer 03/03/21 05:33:05 PM
#85775   Trading board . sorc92 03/03/21 05:30:32 PM
#85774   What board. croutonpanda 03/03/21 05:27:54 PM
#85773   Look across the board ... it was a sorc92 03/03/21 05:17:42 PM
#85772   7 cent Drop WHY? Money Management 03/03/21 05:10:43 PM
#85771   Crazy Day Her Maybe News Probably will be Money Management 03/03/21 05:02:46 PM
#85769   Everything I buy drops, and I bought a BiC_ 03/03/21 04:05:56 PM
#85768   You said a mouthful there sorc92 03/03/21 04:04:17 PM
#85767   How anyone sells at this price baffles me. MikeHarkins 03/03/21 04:04:06 PM
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