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Sophiris Bio, Inc. (SPHS)

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Last Post: 9/17/2017 6:42:03 PM - Followers: 131 - Board type: Free - Posts Today: 0

Sophiris Bio Inc.



Sophiris Bio Inc. is a Canadian urology company with operations based in San Diego developing a late-stage, highly targeted treatment for benign prostatic hyperplasia (BPH or enlarged prostate), a large unsatisfied market. PRX302, the company’s lead candidate for BPH, is designed to be as efficacious as pharmaceuticals, less invasive than the surgical interventions, and without the sexual side effects seen with existing treatments. Sophiris is planning to begin a pivotal trial by the end of 2012.

The pivotal trial is supported by a randomized, controlled Phase IIb study that met the objective and subjective endpoints used as the basis for current BPH drug approvals. Sophiris is advised by world-leading urologists, is backed by experienced investors, and is led by an experienced drug development team that has achieved more than twenty drug approvals including several blockbusters.




 





Ongoing Clinical Development
 
Study Phase Trial Design
PLUS-1
PRX302-3-01 BPH

 

 III On-going/Enrollment Completed (479 patients) Prospective, randomized, double-blind, placebo-controlled, transrectal treatment of PRX302, which will utilize the IPSS outcome measure evaluated at 12 months as the primary endpoint
PRX302-2-7 PCa

 

 IIa Enrolling (approximately 20 patients) Open label, Phase 2a study, evaluating the safety and tolerability of targeted intraprostatic administration of PRX302 to treat men with histologically proven, clinically significant, localized, low to intermediate risk prostate cancer


Completed Clinical Development
 

Study Phase
(pts treated with PRX302		 Trial Design
TRIUMPH
PRX302-2-03 BPH		 IIb (61 pts) Randomized, double-blind, placebo-controlled, transperineal treatment of PRX302
PRX302-2-06 BPH I/II (32 pts) Randomized dose escalation, multicenter trial of a single transrectal intraprostatic treatment of PRX302
PRX302-2-02
Phase 2a BPH		 IIa (18 pts) Open-label, safety, volume escalation clinical trial of a single transperineal treatment of PRX302
PRX302-2-01
BPH		 I (15 pts) Open-label, safety, dose escalation clinical trial of a signal transperineal intraprostatic treatment of PRX302
PRX302 PCa I (24 pts) Open-label, safety and tolerability, dose escalation trial of PRX302 in patients with biopsy-proven, locally-recurrent prostate cancer
PRX302 PCa II (6 pts) Open-label clinical trial in locally-recurrent prostate cancer


$SPHS was $40.00 in 2011 We will be back there soon enough.
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SPHS News: Current Report Filing (8-k) 09/13/2017 04:09:44 PM
SPHS News: Sophiris Bio Secures up to $10 Million in Term Loans from Silicon Valley Bank 09/13/2017 04:05:00 PM
SPHS News: Notice of Effectiveness (effect) 08/31/2017 06:02:22 AM
SPHS News: Securities Registration Statement (simplified Form) (s-3/a) 08/24/2017 04:37:04 PM
SPHS News: Sophiris Bio to Present at the Rodman & Renshaw 19th Annual Global Investment Conference 08/17/2017 08:00:00 AM
PostSubject
#2818   Agree! BurntNAlive 09/17/17 06:42:03 PM
#2817   BurntNAlive, Thanks for the information, and definitely it is Maple tree 09/17/17 04:43:10 PM
#2816   Expecting this to fly during 1 qtr of BurntNAlive 09/16/17 06:05:02 PM
#2815   I bought sphs when it was less than Maple tree 09/16/17 12:25:28 PM
#2814   Love this company soon will save people lives. nymostwanted 08/15/17 06:59:19 PM
#2813   Nice earnings! nymostwanted 08/10/17 07:04:50 PM
#2811   August 8th -15th not confirmed. nymostwanted 07/28/17 05:19:47 PM
#2810   When do we expect it? BurntNAlive 07/28/17 12:14:23 PM
#2809   Should expect news soon coming into earnings report. nymostwanted 07/27/17 05:13:53 PM
#2808   http://thefly.com/landingPageNews.php?id=2581896 nymostwanted 07/25/17 05:56:19 PM
#2807   Excellent article. Just wish it put Sophiris' name Boolsyet 07/24/17 08:20:45 PM
#2806   https://www.google.ca/amp/www.dailymail.co.uk/health/article-4721086/amp/Jab-pro nymostwanted 07/23/17 03:43:10 PM
#2805   Yes far more active! Lnp30 07/11/17 05:14:09 PM
#2804   Thanks for introducing me to stock twits it's nymostwanted 07/11/17 04:10:06 PM
#2803   What a let down this week.. nymostwanted 07/07/17 05:56:44 PM
#2802   Dude get stock twits... Lnp30 07/06/17 04:42:26 AM
#2801   Sphs CEO article click June 27th https://www.linkedin.com/pulse/seeing-hard-re nymostwanted 07/05/17 11:26:36 PM
#2800   https://www.linkedin.com/pulse/seeing-hard-reach-prostate-cancer-makes-easier-tr nymostwanted 07/05/17 11:25:05 PM
#2799   Hoping for some merger news this year. nymostwanted 07/05/17 11:09:15 PM
#2798   Happy 4th of July everyone hope for some nymostwanted 07/04/17 03:10:28 PM
#2797   Lol very funny you wish to get 1.40s.. nymostwanted 07/03/17 02:47:16 PM
#2796   Extremely Bearish Wicked_600hp_67_vette 07/02/17 10:24:32 PM
#2795   Waiting on the 1.40's to cover and go long. Wicked_600hp_67_vette 07/02/17 10:22:02 PM
#2794   Let's continue this uptrend all week show some nymostwanted 06/27/17 07:10:38 PM
#2793   Very soon! BurntNAlive 06/26/17 07:59:54 PM
#2792   Bring me some good news today $ph $ nymostwanted 06/26/17 09:22:28 AM
#2791   the company interested would not need to wait BurntNAlive 06/25/17 05:07:44 PM
#2790   I believe partnership will be done before a Gremlins 06/25/17 01:12:48 PM
#2789   But you know this can go $4 plus nymostwanted 06/25/17 11:13:09 AM
#2788   Is there any chance $sphs will announce dilution flm09 06/25/17 09:56:39 AM
#2787   Thank You! I am waiting for the institutions BurntNAlive 06/24/17 02:42:48 AM
#2786   I certainly hope so. I believe in SPHS Boolsyet 06/24/17 01:36:00 AM
#2785   Small caps usually perform better on the Russell. nymostwanted 06/23/17 07:34:24 PM
#2784   How this would help? I have lot of BurntNAlive 06/23/17 06:50:21 PM
#2783   From next week a different sphs. Russell nymostwanted 06/23/17 04:25:37 PM
#2782   Keep pushing shorts just keep loading up shorts please.. nymostwanted 06/13/17 08:18:55 PM
#2781   Let's hope. Holding 15.5 k shares here still Lnp30 06/12/17 01:49:43 PM
#2780   Yes yes of course, I believe sphs nymostwanted 06/12/17 01:21:06 PM
#2779   You were holding the line during the roughest Lnp30 06/12/17 09:40:21 AM
#2778   I am coming back soon don't mind buying nymostwanted 06/12/17 08:53:18 AM
#2777   I just can't believe you abandoned xxii. Xxii Lnp30 06/12/17 08:37:48 AM
#2776   Wake up SPHS.. nymostwanted 06/07/17 05:07:21 PM
#2775   Thank you good luck to you as well, hwpbnj 06/05/17 07:40:42 PM
#2774   No problem good luck hope you take profits nymostwanted 06/05/17 07:28:40 PM
#2773   Or it's at .30 easy ;). I'm not hwpbnj 06/05/17 07:18:26 PM
#2772   But you know how these bio works right? nymostwanted 06/05/17 07:17:30 PM
#2771   Absolutely. I have plenty of wiggle room. Been hwpbnj 06/05/17 06:51:56 PM
#2770   $PH $ healthy long term.. nymostwanted 06/05/17 06:51:33 PM
#2769   But hey more of you better for me nymostwanted 06/05/17 06:50:38 PM
#2768   I feel sorry for you did you. You nymostwanted 06/05/17 06:49:51 PM
PostSubject
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