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Biotechs
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Sophiris Bio Inc. (SPHS)
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Last Post:
1/26/2021 2:56:42 AM
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Sophiris Bio Inc.
Sophiris Bio Inc. is a Canadian urology company with operations based in San Diego developing a late-stage, highly targeted treatment for benign prostatic hyperplasia (BPH or enlarged prostate), a large unsatisfied market. PRX302, the company’s lead candidate for BPH, is designed to be as efficacious as pharmaceuticals, less invasive than the surgical interventions, and without the sexual side effects seen with existing treatments. Sophiris is planning to begin a pivotal trial by the end of 2012.
The pivotal trial is supported by a randomized, controlled Phase IIb study that met the objective and subjective endpoints used as the basis for current BPH drug approvals. Sophiris is advised by world-leading urologists, is backed by experienced investors, and is led by an experienced drug development team that has achieved more than twenty drug approvals including several blockbusters.
Ongoing Clinical Development
Study
Phase
Trial Design
PLUS-1
PRX302-3-01 BPH
III On-going/Enrollment Completed (479 patients)
Prospective, randomized, double-blind, placebo-controlled, transrectal treatment of PRX302, which will utilize the IPSS outcome measure evaluated at 12 months as the primary endpoint
PRX302-2-7 PCa
IIa Enrolling (approximately 20 patients)
Open label, Phase 2a study, evaluating the safety and tolerability of targeted intraprostatic administration of PRX302 to treat men with histologically proven, clinically significant, localized, low to intermediate risk prostate cancer
Completed Clinical Development
Study
Phase
(pts treated with PRX302
Trial Design
TRIUMPH
PRX302-2-03 BPH
IIb (61 pts)
Randomized, double-blind, placebo-controlled, transperineal treatment of PRX302
PRX302-2-06 BPH
I/II (32 pts)
Randomized dose escalation, multicenter trial of a single transrectal intraprostatic treatment of PRX302
PRX302-2-02
Phase 2a BPH
IIa (18 pts)
Open-label, safety, volume escalation clinical trial of a single transperineal treatment of PRX302
PRX302-2-01
BPH
I (15 pts)
Open-label, safety, dose escalation clinical trial of a signal transperineal intraprostatic treatment of PRX302
PRX302 PCa
I (24 pts)
Open-label, safety and tolerability, dose escalation trial of PRX302 in patients with biopsy-proven, locally-recurrent prostate cancer
PRX302 PCa
II (6 pts)
Open-label clinical trial in locally-recurrent prostate cancer
$SPHS was $40.00 in 2011 We will be back there soon enough.
SPHS
Current Price
Volume:
Bid
Ask
Day's Range
SPHS Detailed Quote
1D
1M
2M
3M
6M
1Y
2Y
3Y
5Y
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Subject
#2956
georgie18Yesterday at 1:18 PM
georgie18
01/26/21 02:56:42 AM
#2955
I dont recommend to buy but it's definitely
Oren1976
10/18/20 11:59:42 PM
#2954
1.2 mill volume
Aarons
09/24/20 04:00:13 PM
#2953
Why we paying SPHS any attention here..? 5/18/20
Aarons
07/15/20 12:44:03 AM
#2952
WHITTENHALLJR good to see you here, room is
KILLERMIKE
06/22/20 09:22:30 AM
#2951
Yep...there's a dropdown on IHUB's quote where you
Eli's Gone
06/20/20 12:49:56 PM
#2950
Ahhh thanks .0117 I see on my TD Ameritrade
WHITTENHALLJR
06/20/20 12:29:56 PM
#2949
SPHS was delisted from the NASDAQ on March
Eli's Gone
06/20/20 12:13:24 PM
#2948
Why is this stuck at $.23? Is it
WHITTENHALLJR
06/20/20 12:05:54 PM
#2947
The rose bush is in full bloom, how
KILLERMIKE
06/16/20 09:29:21 AM
#2946
WOW, no one is paying attention here
KILLERMIKE
06/15/20 12:43:23 PM
#2945
SPHS...007...Reversal Hammer...added here on the Oversold Pincher...Open Gap...0
georgie18
06/05/20 05:42:01 AM
#2944
Pay attention here, something is up with this one.
KILLERMIKE
06/05/20 12:16:44 AM
#2943
Oversold. Should bounce nicely from here on
WARHAMMER
05/27/20 12:12:56 PM
#2942
Needs more kaboom
WARHAMMER
05/27/20 10:50:41 AM
#2941
SPHS huge gap above .10. Volume means
WARHAMMER
05/27/20 10:47:34 AM
#2940
Needs a lot more volume...
retireat40
05/27/20 10:36:13 AM
#2939
Hey bro sorry I didn't get back with
marknet
05/27/20 12:06:03 AM
#2937
Kaboom day here
abazaba375
05/26/20 05:40:14 PM
#2936
Solid close. .02 break and hold tomorrow.
marknet
05/26/20 05:28:31 PM
#2935
Let's close above .02 today. Break .05 tomorrow.
marknet
05/26/20 01:22:30 PM
#2934
Weee. More in store me thinks. Much more.
WARHAMMER
05/26/20 12:34:33 PM
#2933
Weeeeee cashes it for a friend
abazaba375
05/26/20 12:30:44 PM
#2932
L2 looks very thin for a bounce back
ShaneO19
05/26/20 11:40:27 AM
#2931
Welp.... lol
Awl416
05/26/20 11:26:55 AM
#2930
Break through those .02s and it's game on.
marknet
05/26/20 10:57:07 AM
#2929
Let’s do this!
WARHAMMER
05/26/20 10:50:28 AM
#2928
Big wall at .018.
retireat40
05/26/20 10:49:09 AM
#2927
Small amounts on the ask. Won't take much
marknet
05/26/20 10:43:35 AM
#2926
Nice one for Bottom fishers
Awl416
05/26/20 10:41:17 AM
#2925
Agreed. Slow and steady. Nice accumulation and building
marknet
05/26/20 10:40:51 AM
#2924
Just the first leg imo
hb90
05/26/20 10:35:02 AM
#2923
Bids creeping up. Very solid trading here.
marknet
05/26/20 10:34:16 AM
#2922
Almost broke out...nice move though.
retireat40
05/26/20 10:30:59 AM
#2921
Already almost passed Friday's volume with majority traded
marknet
05/26/20 10:29:14 AM
#2920
.10+ maybe this week.
marknet
05/26/20 10:26:13 AM
#2919
Think they know where this is going! Likely
marknet
05/26/20 10:24:59 AM
#2918
Definitely can see that today. Really solid here.
marknet
05/26/20 10:23:31 AM
#2917
SPHS buying some for the real move
WARHAMMER
05/26/20 10:23:25 AM
#2916
1 mil bid at 0125
hb90
05/26/20 10:21:34 AM
#2915
Good amount of shares exchanged 015+ next leg
hb90
05/26/20 10:19:51 AM
#2914
Let's get through .06s then there's nothing til .7056.
marknet
05/26/20 10:05:39 AM
#2913
Awesome volume! Lets take out those .03s.
marknet
05/26/20 09:55:54 AM
#2912
Huge volume! .04s in sight.
marknet
05/26/20 09:54:21 AM
#2911
Break through .016 and and whole lot of
marknet
05/26/20 09:53:14 AM
#2910
Indeed
hb90
05/26/20 09:49:19 AM
#2909
.01 break and hold should send this.
marknet
05/26/20 09:48:17 AM
#2908
Nice volume first few minutes. Crazy thin stock!
hb90
05/26/20 09:34:45 AM
#2907
Huge accumulation on Friday on 1.8 million volume.
marknet
05/25/20 08:33:04 PM
#2906
#1 small cap performer on Friday.
marknet
05/25/20 08:14:56 PM
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