Sio Gene Therapies Inc (fka SIOX)

[SurgeGuy2.0]

Looks like another Pmp and dump from MMs on twitter

[realfast95]

Axovant Gene Therapies Receives Rare Pediatric Disease Designation for AXO-AAV-GM1 for GM1 Gangliosidosis
October 09 2020 - 07:00AM
GlobeNewswire Inc.


Axovant Gene Therapies Ltd. (NASDAQ: AXGT), a clinical-stage company developing innovative gene therapies for neurological diseases, today announced that it has received Rare Pediatric Disease Designation from the U.S. Food and Drug Administration (FDA) for AXO-AAV-GM1, an AAV9-based gene therapy delivered via a single intravenous administration that is in Phase 1/2 development for GM1 gangliosidosis. In addition to the Rare Pediatric Disease designation, AXO-AAV-GM1 has Orphan Drug designation and is the only gene therapy in clinical development for both infantile (Type I) and juvenile (Type II) GM1 gangliosidosis.

“Receiving Rare Pediatric Disease Designation in addition to the previously granted Orphan Drug Designation for AXO-AAV-GM1 highlights the importance of expediting a therapy for GM1 Gangliosidosis, a progressive, fatal, pediatric disease with no approved treatment options,” said Sean O’Bryan, Senior Vice President, Regulatory Affairs & Quality. “AXO-AAV-GM1 is the first gene therapy to enter clinical trials for GM1 gangliosidosis and has the potential to provide meaningful clinical benefit to both Type I and Type II patients.”

Axovant is on-track to report 6-month Stage 1 data from the low dose juvenile cohort (Type II) by the fourth quarter of 2020, and expects to initiate the high dose cohort which includes infantile (Type I) and juvenile (Type II) patients in the second half of 2020.

GM1 Gangliosidosis is a progressive and fatal pediatric lysosomal storage disorder caused by mutations in the GLB1 gene leading to impaired production of the ß-galactosidase enzyme. Currently, there are no approved treatment options for GM1 Gangliosidosis.

The FDA defines a rare pediatric disease as a serious or life-threatening disease in which the disease manifestations primarily affect individuals aged from birth to 18 years. Pediatric diseases recognized as “rare” affect under 200,000 people in the United States.

[vwlibra]

BUMP: TR & Guggenheim Strong Buy ratings hold

https://www.tipranks.com/stocks/axgt/price-target

https://dakotafinancialnews.com/2020/07/14/axovant-gene-therapies-nasdaqaxgt-receives-market-perform-rating-from-guggenheim.html


Interest is maintaining, with chatter on social media as well.

[Asterixus]

Orphan Designation Status




https://www.accessdata.fda.gov/scripts/opdlisting/oopd/detailedIndex.cfm?cfgridkey=714719

[Zmill]

Research for those new to the board, or those looking for more insights https://msmoneymoves.com/2019/09/02/diversified-gene-therapy-pipeline-makes-axovant-sciences-nasdaq-axgt-a-compelling-opportunity/

[Big Beef]

Good day Zombono!

[Big Beef]

Hey Clay $8 today bet on it.. sorry about Firing you lol joke!

[Big Beef]

Clay,, you're Fired !

[Imott]

Big move upside coming and Clay didn't want to post me a video.

[JUST 10-11-12]

20 bucks

[zambono]

Best wishes

[Big Beef]

Thanks Z, Im in this for the long haul hopefully Gene therapy catches on fire like it did years ago.. I owned HGSI years ago when GSK bought them out I believe 2012... Gene Therapy has come a long way, the future is looking more and more promising... Biotech's has always been my passion...

[zambono]

It’s on its way, has to hit $8 just to be at $1 pre split. Rumors of an upcoming offering, let’s see how it fares. Price needs to be between $16 and $20 just to match the previous range.

[Big Beef]

Wake up people:: Time to get this party started... next target 7.65 and then Boom!

[Big Beef]

Hard to be Bullish or buy more if the price can't stay above $6.50







Popeye jr.

[Imott]

Congratulations to David Nassif as new CFO! One thing for sure, the Sun did rise this morning and the stock will trade well!

[Imott]

It's going to be good times when the next chart video comes!

[Imott]

Yep, fearless, first stop will be $12!

[Imott]

Perfect video for buying the dip. I made $6 psychological support and added some pennies! Now to $64

[Big Beef]

This will be a roller coaster ride for sure,strapped $in

[JUST 10-11-12]

Targets from six analysts: low. $16. Average. $36. High. $64.
No joking!

[ClayTrader]

* * $AXGT Video Chart 06-21-2019 * *

Link to Video - click here to watch the technical chart video

[JUST 10-11-12]

Not an expert... seen Georgejill on it., who knows more about biochem than I, I have a chemical background.

[Fat Thor]

Predictions on how long it takes to climb to $18....to buy or not to buy.

[crudeoil24]

Axovant Shares Up 42% on Partnership, Analyst Coverage -- Update
11:53 am ET June 21, 2019 (Dow Jones) Print
By Chris Wack

Shares of Axovant Gene Therapies Ltd. (AXGT) rose 42% to $8.21 after signing a development and commercialization partnership, and having its stock covered by a stock analyst.

The clinical stage gene therapy company said Thursday that it has signed a strategic partnership with Yposkesi, where Yposkesi will provide expertise in process development, technology transfer, manufacturing scale-up, quality control and quality assurance.

Axovant said that the ongoing prioritized access for manufacturing resources will support Axovant's gene therapy programs as they proceed through development and commercialization, with an initial focus on the AAV-based gene therapies.

The company also had its stock initiated at Outperform by SVB Leerink, who set a price target at $18.00 a share.

Write to Chris Wack at [e-mail]

(END) Dow Jones Newswires

June 21, 2019 11:53 ET (15:53 GMT)

Copyright (c) 2019 Dow Jones & Company, Inc.

[JUST 10-11-12]

Over 64 inst. holdrrs; and lots of insiders too.

[JUST 10-11-12]

Buyout cadidate

[crudeoil24]

Translates into exponential revenue growth > AXGT.

[crudeoil24]

Huge catalyst: " Axovant said that the continuing prioritized access for manufacturing resources will support Axovant's gene therapy programs as they proceed through development and commercialization."

[zambono]

$AXGT going for $9 , 50% gain for the day

[zambono]

$AXGT up 40% over $1 prior to R/S price

[crudeoil24]

Tutes > University endowment funds loading 100k blocks.

AXGT

[crudeoil24]

Huge buys coming in; halted by circuit breakers > $$$$$

[zambono]

$AXGT up 20% at open, surely shorts will jump in in the AM, but they will want to get out in the PM

[crudeoil24]

Axovant Gene Therapies started at outperform with $18 stock price target at SVB Leerink
8:07 am ET June 21, 2019 (MarketWatch)
Share
Print
(END) Dow Jones Newswires

June 21, 2019 08:07 ET (12:07 GMT)

Copyright (c) 2019 Dow Jones & Company, Inc.

[zambono]

$AXGT CEO and director buy thousands of shares. If they believe it’s going up soon, then it’s a good time to jump in.

[Fat Thor]

Fins are out, up after hours.

[locksflooring]

NOTICE HOW SILENT MANAGEMENT IS, AS AXGT SINKS TO THE GROUND!

[locksflooring]

TIMBERRRRRRRRR AXGT ! THIS STOCKS SUCKS!

[Inoviorulez]

Axovant positive 6-month results in Axo-lenti-pd for parkinson's disease https://www.globenewswire.com/news-release/2019/06/06/1865234/0/en/Axovant-Announces-6-Month-Follow-Up-Data-From-First-Cohort-of-SUNRISE-PD-Phase-2-Trial-of-AXO-Lenti-PD-and-Pipeline-Update.html

[georgejjl]

AXOVANT ANNOUNCES GLOBAL LICENSING AGREEMENT FOR AXO-AAV-OPMD PROGRAM FOR TREATMENT OF OCULOPHARYNGEAL MUSCULAR DYSTROPHY AND BROADER PLATFORM COLLABORATION WITH BENITEC BIOPHARMA

********************************************************************

Request for Trading Halt
In accordance with ASX Listing Rule 17.1, Benitec Biopharma Limited (ASX: BLT; NASDAQ: BNTC; NASDAQ:
BNTCW) (Benitec) requests a trading halt of its securities, effective immediately.
For the purposes of the trading halt, Benitec provides the following information:
(a) Benitec is seeking the trading halt as it expects to make an announcement to the ASX in relation to one of its
existing material contracts;
(b) Benitec requests the trading halt be put in place until the earlier of the commencement of trading on Tuesday 11
June 2019, or when an announcement is released to the market; and
(c) Benitec is not aware of any reason why the trading halt should not be granted or of any other information
necessary to inform the market about the trading halt.
Should you have any queries in relation to this trading halt request, please do not hesitate to contact me.
Yours faithfully
Oliver Kidd
Company Secretary

https://blt.irmau.com/irm/PDF/2071_0/TradingHalt

https://blt.irmau.com/irm/PDF/2069_0/Becomingasubstantialholder

What's up???

Good luck and GOD bless,

[Inoviorulez]

Many Presentations coming up for AXGT , I expect new data from most of the studies soon.

https://ih.advfn.com/stock-market/NASDAQ/axovant-sciences-ltd-AXGT/stock-news/80035495/axovant-to-present-at-upcoming-conferences-in-june

[locksflooring]

AXGT MANAGEMENT SUCKS THEIR REVERSE SPLIT WAS A KISS OF DEATH!

[Inoviorulez]

tough go around so far, but upcoming catalysts should quickly turn things around. I'm holding AXGT for the long-term.

[Inoviorulez]

Conference set for tomorrow at 2:00 p.m EST hopefully maybe some results in the morning as well for AXGT

https://ih.advfn.com/stock-market/NASDAQ/axovant-sciences-ltd-AXGT/stock-news/79952124/axovant-to-present-at-2019-rbc-capital-markets-glo

[locksflooring]

BWAHAHAHAHAHAHAHA! AXGT WILL BE REVERSE SPLITTING AGAIN SOON! STAY TUNED!

[Inoviorulez]

News Axovant dosed first patient GM1 gangliodosis

https://finance.yahoo.com/news/axovant-announces-dosing-first-patient-200500914.html

[locksflooring]

TIMBERRRRRRRRRRRRRR AXGT !

[locksflooring]

BWAHAHAHAHAHA! THIS CHITTY STOCK WILL BE BACK AT $1.00 EVEN AFTER THE REVERSE SPLIT! MANAGEMENT OF AXGT IS PATHETIC!

[Inoviorulez]

Management for AXGT is the best. They got Dr. Fraser Wright as the Chief Technology Officer who co-founded Spark Therapeutics. You are crazy.