SciSparc Ltd (SPRC)

[jedijazz]

The Company announced the publication of a manuscript by Dr. Michael. H Bloch et al. The manuscript teaches the uses of its proprietary drug candidate SCI-110 for TS as demonstrated in a study conducted at the Department of Psychiatry, and the Child Study Center at Yale University in New Haven, Connecticut, USA.

[jedijazz]

About SciSparc (NASDAQ:SPRC):

SciSparc Ltd. is a specialty clinical-stage pharmaceutical company led by an experienced team of senior executives and scientists. Our focus is on creating and enhancing a portfolio of technologies and assets based on cannabinoid pharmaceuticals. With this focus, the Company is currently engaged in the following drug development programs based on THC and/or non-psychoactive cannabidiol (CBD): SCI-110 for the treatment of Tourette Syndrome and for the treatment of obstructive sleep apnea; SCI-160 for the treatment of pain; and SCI-210 for the treatment of autism spectrum disorder and epilepsy.

[jedijazz]

SciSparc Provides Update Dec. 29, 2021 /PRNewswire/ -- SciSparc Ltd. (NASDAQ: SPRC), a specialty, clinical-stage pharmaceutical company focusing on the development of therapies to treat disorders of the central nervous system (the "Company" or "SciSparc"), today provides updates regarding its activities in 2021.

[ProfitScout]

SciSparc Provides Updates Upon Conclusion of 2021

TEL AVIV, Israel, Dec. 29, 2021 /PRNewswire/ -- SciSparc Ltd. (NASDAQ: SPRC), a specialty, clinical-stage pharmaceutical company focusing on the development of therapies to treat disorders of the central nervous system (the "Company" or "SciSparc"), today provides updates regarding its activities in 2021.

Itzhak Shrem, Chairman of the board of SciSparc, said, "We are excited to conclude a very eventful and successful year. We reached several important milestones, among them the uplisting of our ordinary shares to the Nasdaq Capital Market."

"Looking forward to 2022, we are aiming to show progress in our clinical programs in Tourette Syndrome (TS), Alzheimer's disease (AD) and Agitation and Autism Spectrum Disorder (ASD). We are planning on expanding our partners network and continuing to raise awareness of our unique technologies and novel treatments by showcasing them in leading events worldwide. We plan on strengthening our professional team and advisory board as well as increasing exposure to investors in North America," added Amitai Weiss, Chief Executive Officer of SciSparc.

In 2021, the Company completed a corporate rebranding that better represent its current business focus and listed its ordinary shares on the Nasdaq Capital Market.

Financing:

During 2021, the Company raised more than $8 million from institutional and accredited investors in a private placement.

IP Protection:

During 2021, the Company was awarded two patents from the Australian Patent Office and one from the Japanese Patent Office concerning the proprietary compounds and methods underlying the Company's core technologies: Pharmaceutical compositions comprising cannabinoids and N-acylethanolamines, and methods for their use in preventing and treating a variety of cannabinoid-treatable conditions.

Pipeline Status:

SCI–110 for Tourette Syndrome- Towards Phase IIb Clinical Trial

During 2021, the Company announced a number of updates regarding its Phase IIb clinical study in TS using the proprietary cannabinoid-based treatment- SCI-110. The study will be led by Prof. Kirsten Mueller- Vahl from Hanover Medical School. The Company has begun preparations that will facilitate the commencement of the clinical study and engaged with a contract research organization (CRO) to provide support for the trial. In addition, SciSparc had established its supply chain infrastructure for the manufacturing and delivering of the SCI-110 drug.

Also, the Company announced the publication of a manuscript by Dr. Michael. H Bloch et al. The manuscript teaches the uses of its proprietary drug candidate SCI-110 for TS as demonstrated in a study conducted at the Department of Psychiatry, and the Child Study Center at Yale University in New Haven, Connecticut, USA.

SCI–110 for Alzheimer's disease and Agitation- Towards Phase IIa Clinical Trial

During 2021, the Company received approval from the Israeli Ministry of Health and Helsinki Committee to commence a Phase IIa Clinical Trial of SCI-110 in patients with AD and Agitation.

The Company signed an agreement with The Israeli Medical Center for Alzheimer's to conduct a Phase IIa clinical trial to evaluate the safety, tolerability and efficacy of SCI-110 in patients with AD and agitation using the Company's proprietary drug candidate.

SCI–210 for Status Epilepticus

During 2021, the Company announced it has entered an agreement with The Sheba Fund for Health Services and Research, to perform a pre-clinical study for the evaluation of the Company's SCI-210 drug development program, a proprietary novel pharmaceutical preparation containing non-psychoactive cannabinoid cannabidiol (CBD) and palmitoylethanolamide (PEA) for the treatment of Status Epilepticus (SE). The study, which is led by Prof. Nicola Maggio, a senior neurologist and a neuroscientist at the Chaim Sheba Medical Center, was already initiated after SciSparc received all the necessary approvals, including the Israeli Medical Cannabis Unit (IMCA) as well as the ethical committee approval.

SCI-160 for Pain

In 2021, the Company announced positive top-line results for its proprietary compound, SCI-160, in a controlled pre-clinical trial on neuropathic and post-operative pain. The study was conducted at the University of Calgary under the leadership of Dr. Tuan Trang, Associate Professor in the Department of Comparative Biology & Experimental Medicine, a renowned researcher in the clinical management of pain conditions.

About SciSparc (NASDAQ:SPRC):

SciSparc Ltd. is a specialty clinical-stage pharmaceutical company led by an experienced team of senior executives and scientists. Our focus is on creating and enhancing a portfolio of technologies and assets based on cannabinoid pharmaceuticals. With this focus, the Company is currently engaged in the following drug development programs based on THC and/or non-psychoactive cannabidiol (CBD): SCI-110 for the treatment of Tourette Syndrome and for the treatment of obstructive sleep apnea; SCI-160 for the treatment of pain; and SCI-210 for the treatment of autism spectrum disorder and epilepsy.

Forward-Looking Statements:

This press release contains forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995 and other U.S. federal securities laws. For example, SciSparc is using forward-looking statements when it discusses the expected medical benefits of its therapeutics and drug candidates, its plans to expand its partners network and progress its clinical programs for TS, AD and Agitation, SE and pain, its plans to raise awareness of its technologies and novel treatments by showcasing them in leading events worldwide and its plans to strengthen its professional team and advisory board as well as increase exposure to investors in North America. Because such statements deal with future events and are based on SciSparc's current expectations, they are subject to various risks and uncertainties and actual results, performance or achievements of SciSparc could differ materially from those described in or implied by the statements in this press release. The forward-looking statements contained or implied in this press release are subject to other risks and uncertainties, including those discussed under the heading "Risk Factors" in SciSparc's Annual Report on Form 20-F filed with the U.S. Securities and Exchange Commission (the "SEC") on March 30, 2021, and in subsequent filings with the SEC. Except as otherwise required by law, SciSparc disclaims any intention or obligation to update or revise any forward-looking statements, which speak only as of the date they were made, whether as a result of new information, future events or circumstances or otherwise.

Investor Contact:
[e-mail]
Tel: [phone]


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SOURCE SciSparc Ltd.

[Johnny_C]

Very low float here. Looks like Company was a complete mess but they are in a great space. This could be a great turnaround. Tried to buy offering but they were fully subsribed.

A Phase 2 CBD drug trial for autism is very interesting proveided they get the funding

[Johnny_C]

Very interesting valuation here

[a surfer]

Moving right on upwards.

[Renee]

TRPXY changed to SPRCY:

https://otce.finra.org/otce/dailyList?viewType=Symbol%2FName%20Changes

[sindram]

Does anyone know the new isin???

[Renee]

TRPXY: effective Feb. 8,2021 Therapix Biosciences Ltd. ADR will change to SciSparc Ltd. ADR:

https://otce.finra.org/otce/dailyList?viewType=Symbol%2FName%20Changes

[Trade22]

Therapix Biosciences to Collaborate with The University of Calgary to Further Examine its Proprietary Drug Candidate THX-160 for Pain
"In the era of America's deadly opioid crisis, cutting-edge pain therapeutics like THX-160 possess the potential to be a new and effective treatment option for pain patients, reducing the risks of opiate addiction."

http://therapix.investorroom.com/2020-12-02-Therapix-Biosciences-to-Collaborate-with-The-University-of-Calgary-to-Further-Examine-its-Proprietary-Drug-Candidate-THX-160-for-Pain

TEL AVIV, Israel, Dec. 2, 2020 /PRNewswire/ -- Therapix Biosciences Ltd. ("Therapix" or the "Company") (OTC Pink: TRPXY), a specialty, clinical-stage pharmaceutical company focusing on the development of cannabinoid-based treatments, today announced a collaboration between the company and The University of Calgary to further evaluate the analgesic effect of Therapix's CB2R agonist proprietary drug candidate, THX-160.

This collaboration is expected to facilitate the further development of THX-160 for the treatment of pain, following efficacy pre-clinical studies that demonstrated the analgesic advantages of THX-160 over control. Moreover, THX-160's anti-analgesic effects, in these studies, were comparable and even greater in some instances over high-dose morphine analgesic effects.

Therapix_Biosciences_Logo
Therapix's drug candidate THX-160 is an innovative CB2 receptor agonist, which was synthesized by Raphael Mechoulam, Ph.D., Professor of Medicinal Chemistry at the Hebrew University, head of the Medicinal Chemistry Lab and the President of Multidisciplinary Center for Cannabinoid Research and a recipient of the Israel Prize in Exact Sciences - Chemistry and EMET Prize in Exact Sciences – Chemistry, as well as a member of the Therapix Scientific Advisory Board.

"Although cannabinoids have therapeutic potential, their psychoactive effects, associated with the usage of CB1 receptor (CB1R) agonists, have largely limited their use in clinical practice; CB2 receptors (CB2R) agonists do not cause such effects. Quite the opposite, CB2R agonists are known to exhibit mainly a protective effect, acting on pain, in inflammation, in neurological diseases and in many other disease states," stated Prof. Mechoulam. "For that reason, I have synthesized in my laboratory a molecule (HU-433; THX-160), which does not activate the CB1 receptor, but affects CB2R alone. This molecule was shown in pre-clinical studies performed by Therapix to lower pain significantly. I believe that our new molecule, which so far has not shown any undesirable effects in animal studies, holds a significant promise to become a major drug as it uses a natural pathway to oppose pain."

"We are excited to partner on this project with the University of Calgary under the leadership of Dr. Tuan Trang, Associate Professor in the Department of Comparative Biology & Experimental Medicine at the University of Calgary and a renowned researcher in the clinical management of pain conditions. We believe this research could further demonstrate the analgesic clinical utility of THX-160," said Dr. Adi Zuloff-Shani, Chief Technologies Officer of Therapix. "In the era of America's deadly opioid crisis and following the declaration of a nationwide public health emergency and in fitting with the five-point opioid strategy formed to address the national opioid crisis, cutting-edge pain therapeutics like THX-160 possess the potential to be a new and effective treatment option for pain patients, and reduce the risks of opiate addiction."

[Trade22]

Therapix Biosciences Issues CEO Letter to its Shareholders

http://therapix.investorroom.com/2020-11-30-Therapix-Biosciences-Issues-CEO-Letter-to-its-Shareholders

TEL AVIV, Israel, Nov. 30, 2020 /PRNewswire/ -- Therapix Biosciences Ltd. (OTC Pink: TRPXY) (the "Company"), a specialty, clinical-stage pharmaceutical company focusing on the development of cannabinoid-based pharmaceuticals, today released a letter to its shareholders from its Chief Executive Officer, Mr. Amitay Weiss.


Dear Shareholders,

I am pleased to reach out for the first time since I was appointed CEO and as the company enters its exciting new chapter ahead. Recently, the company's Board of Directors and CEO were replaced by a new, motivated and experienced team; one that is committed to turning the company around and steering it in the right direction.

I can imagine that some of you experienced many disappointments in the past years. That said, after close examination of the company's priorities, I am confident that the new management (me included) possesses the right tools to reach the company's true potential and provide value to its shareholders.

Our first priority was to ensure the company's future by reinforcing its financial strength and establishing a budget that will allow us to achieve notable milestones. Recently, we announced a $4.2 million equity offering.

Strengthening the company's financial structure will allow us to work towards advancing our technology and pursuing strategic opportunities including expanding our pipeline by exploring ways to strengthen our portfolio through internal and external business growth strategies of innovative technologies and products, given sufficient capital for funding.

Currently the company has several pre-clinical and clinical programs in its high potential R&D pipeline. Additionally, the company also has a valuable asset addressing the supplement market; CannAmideTM; an Endocannabinoid-like compound with a broad spectrum of pharmacological properties. CannAmideTM has been designated a product license issuance from the Natural and Non-prescription Health Products Directorate (NNHPD) from Health Canada. We are now investigating commercialization of the product in Canada and other jurisdictions.

We intend to maximize every asset the company holds through commercialization, advancing clinical programs, licensing agreements, new partnerships and more. Our only focus is to rehabilitate Therapix and restore your trust in the company and its management so that we can together reach its full potential.

Sincerely yours,

Amitay Weiss

Forward-Looking Statements:

This letter contains forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995 and other Federal securities laws. For example, the Company is using forward-looking statements when it discusses its future plans and goals, including reaching the company's potential, providing value to shareholders, advancing technology and pursuing strategic opportunities, maximizing the company's assets and rehabilitating the company. Because such statements deal with future events and are based on the Company's current expectations, they are subject to various risks and uncertainties and actual results, performance or achievements of the Company could differ materially from those described in or implied by the statements in this letter. The forward-looking statements contained or implied in this letter are subject to other risks and uncertainties, including those discussed under the heading "Risk Factors" the Company's Annual Report on Form 20-F filed with the SEC on June 15, 2020, and in subsequent filings with the U.S. Securities and Exchange Commission. Except as otherwise required by law, the Company disclaims any intention or obligation to update or revise any forward-looking statements, which speak only as of the date they were made, whether as a result of new information, future events or circumstances or otherwise.

[Trade22]

August 21, 2020 http://therapix.investorroom.com/2020-08-21-Therapix-Biosciences-Announces-Replacement-of-its-Board-of-Directors

Therapix Biosciences Announces Replacement of its Board of Directors

TEL AVIV, Israel, Aug. 21, 2020 /PRNewswire/ -- Therapix Biosciences Ltd. (OTC Pink: TRPXY) (the "Company"), a specialty, clinical-stage pharmaceutical company focusing on the development of cannabinoid-based treatments, announced today the replacement of its board of directors. The Company's new six-member board of directors will include Itschak Shrem, Amitay Weiss, Moshe Revach, Lior Amit, Lior Vider and Liat Sidi.

Itschak Shrem was appointed as Chairman of the new board of directors, and Amitay Weiss, in addition to his membership with the board, will assume the position of Chief Executive Officer of the Company.

"I'm pleased to accept the responsibility of, and look forward to, leading the Company in a new and exciting direction," said Mr. Itschak Shrem, the Company's new Chairman of the board of directors. "Under new leadership, I'm confident the Company will finally maximize its impressive potential and, at the same time, deliver a deserving return to our shareholders," he continued.

Itschak Shrem has more than 40 years of experience in financial markets and venture capital. In 1991, Mr. Shrem founded Dovrat Shrem Ltd., an investment banking, management and technology company. Prior to that, he spent 15 years at Clal Israel Ltd., where he served in various capacities, including chief operating officer, and was responsible for capital markets and insurance businesses. In 1993, Mr. Shrem founded Pitango Venture Capital Fund (formerly, Polaris) and served as a partner of Pitango Funds I, II and III. He has been the Managing Director of Yaad Consulting 1995 Ltd. since 1995. Mr. Shrem currently serves on the board of directors of Rail Visions Ltd. Previously, Mr. Shrem served on the board of Tel-Aviv Sourasky Medical Center, the Weizman Institute Eden Spring Ltd., Nano Dimension Ltd., Ormat Industries Ltd., Retalix Ltd. and as chairman of Sphera Funds Management Ltd. Mr. Shrem holds a B.A in Economics and Accounting from Bar-Ilan University and an M.B.A. from Tel-Aviv University.

Amitay Weiss currently serves as chairman of the board of directors of P.L.T Financial Services Ltd., as chairman of the board of directors of Matomy Media Group Ltd. and as an external director of Cofix Group Ltd. In 2016, Mr. Weiss founded Amitay Wiss Management Ltd. and now serves as its chief executive officer. From 2001 until 2015, Mr. Weiss served as vice president of business marketing & development and in various other positions at Bank Poalei Agudat Israel Ltd. (PAGI) from the First International Bank of Israel group. Mr. Weiss holds a B.A in economics from New Engand College, M.B.A. in business administration from Ono Academic College in Israel, an Israeli branch of University of Manchester and LL.B from the Ono Academic College.

Lior Amit serves as a consultant to both private and public companies as well as individuals. Mr. Amit serves as director of ScoutCam Inc., Matomy Ltd., Nirplex Ltd., Ronimar Ltd., Endemol Israel Ltd. and B.S.S.CH. - The Israeli Credit Insurance Company Ltd. Mr. Amit previously served as chief financial officer for BBR Saatchi & Saatchi Group from 1996 to 2013. Mr. Amit is an Israeli Certified Public Accountant. Mr. Amit holds a B.A in economics and accounting and M.B.A. in insurance and finance from Tel-Aviv University.

Lior Vider serves as a senior investment portfolio manager at Epsilon Investment House Ltd. since 2010. Mr. Vider previously served as chief investment manager for Impact Investment Management Ltd., from the Union Bank group from 2007 to 2010 and as chairman of the board of directors and member of the group's investment committee of Rahkia Capital Markets Ltd. from 2006 to 2007. Mr. Vider also served as manager of the financial desk and as a trader in trust funds of Ilanot Discount from 2003 to 2006. Mr. Vider founded and managed sponser.co.il, a financial portal specializing in services for investors from 2005 to 2017. Mr. Vider holds a B.A in industry and management engineering from Shenkar College in Israel.

Moshe Revach serves as deputy mayor of the city of Ramat Gan, Israel, has held both the sports and government relations portfolios in the Ramat Gan municipality since 2013, and has served in various other Ramat Gan municipality positions since 2008. Mr. Revach serves as a director of L.L.N IT solutions, a wholly-owned subsidiary of the Jewish Agency for Israel and of Biomedico Hadarim Ltd. Mr. Revach previously served as a director of the RPG Economic Society and Jewish Experience Company on behalf of the Jewish Agency. Mr. Revach holds an LL.B from the Ono Academic College, Israel, and B.A in management and economics from the University of Derby.

Liat Sidi serves as the manager of the accounting department for Foresight Autonomous Holdings Ltd. Ms. Sidi previously served as an accountant for Panaxia Labs Israel Ltd. from 2015 to 2020 and as an accountant for Soho Real Estate Ltd. from 2015 to 2016. Ms. Sidi also served as an accountant for Feldman-Felco Ltd. from 2006 to 2010 and as an accountant for Eli Abraham accounting firm from 2000 to 2006. Ms. Sidi completed tax, finance and accounting studies in Ramat Gan College of Accounting.

[Renee]

TRPXY: effective Oct. 19,2020 a one for 70 reverse split:

https://otce.finra.org/otce/dailyList?viewType=Symbol%2FName%20Changes

[L K]

Yy

[LordAsriel]

I don’t think it ever went down to 10 cents.

I only see 18 cents on the chart

[BDEZ]

Yeah just found out about it tonite after checking my account. Very strange.

[JBaker9021]

It is climbing back up! All those lucky enough to score shares at .10 have already doubled their money.

[JBaker9021]

Anyone else going to bag hold?
Sell now for 50% loss, or wait it out. Screw it, I'm going down with the ship. 8000 shares bought at .31

[Renee]

TRPX changed to TRPXY. Delisted from the Nasdaq to the OTC:


https://otce.finra.org/otce/dailyList?viewType=Additions

[sindram]

Hold your shares... buyout offer will come soon $$$

[xlofer]

If they offer how much you think will be offer and being still a shareholders do we get anything since we will be on OTC

[outnabout]

In my opinion, I think Pure Capital is going to make an offer. Again, this is only an opinion. May not happen at all.

[RJ Trotts]

thanks for the info, best to all here

[outnabout]

Unless we are told otherwise. This will begin trading on the OTC tomorrow.

[RJ Trotts]

Will this trade on another exchange tomorrow? On the OTC, or what is the story here? Thanks for any info.

[littletyke]

I got burned this time. Play with fire and sometimes...

[Almost A Myth]

Wow, I didn't expect this. I've been an observer here for a while, never took a position.

https://finance.yahoo.com/news/therapix-biosciences-receives-notice-delisting-111000255.html

[jablome]

got 15k shares

[littletyke]

In for another swing to $1+

[kzivann]

Friday dip.

TRPX

[littletyke]

What a move today

[littletyke]

Nice move today, still waiting for that gap fill @ .90

[CapGainsman]

I agree with your analysis Littletyke. These guys at Capital Point are NOT Happy Campers. Surprised this filing isn't getting more after hours attention.

[littletyke]

Interesting filings today. Potential takeover in the works. This Capital Point company means business. Should be an interesting few weeks here.

[littletyke]

Held well on the dip this AM. Nice support at .50 News sends this to dollar.

[Stoquer1]

.61 breakout sends it to 1.00++

[littletyke]

Little resistance point at .60, .50 looks to be new support. Gap at .90 needs to be filled.

[Runners123]

https://charts.stocktwits.com/production/original_215222047.PNG

[Runners123]

This stock is on fire over on stock twits com on fire

[Runners123]

Morgan Stanley still owns 23,000,000 shares people

[Runners123]

Way over sold

[Runners123]

This wants to explode, as the profit takers get cleaned out

[Runners123]

Israeli companies tend to be far more legit than ones on the other side of the water lol.

[cep2535]

Maybe a $1.00.. moving nicely

[Runners123]

This is a $5 stock?

[BDEZ]

Looks like it's headed that way, love it.

TRPX

[cep2535]

Look at all that accumulation. Moving beautifully

[littletyke]

Nice action into close

[littletyke]

Have a good feeling on this stock. We should be getting confirmation from Nasdaq of market cap compliancy and then the 10k. Once we get through that milestone the fun really begins.

New CEO was brought here for his business and capital expertise. THC/Covid link could be something to watch. I think we will get one sizable merger or acquisition.

With this tiny float, once she goes she will go fast and hard. Looking at the chart $2+ is easily achievable in the short term once the volume rolls in.