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"...there were no deaths and four hospitalizations, of which three were from the placebo arm and one from the Bucillamine low dose group (300mg/day)."
Talk about self owing oneself. lololsss
Its yet another clear demonstration of the lack of basic knowledge among "agitators".
It was the DSMB that recommended eliminating the low dosage ye cited, opting instead for the 600mg/day dosage where there were ZERO deaths and hospitalizations ye numpt.
Keep exposing yerself as a complete fraud with an agenda.
Wont even grace the other buffoonish "ice pack" post with an answer since it deserves none and only serves to expose the silliness of you lot.
Ice packs will reduce fever too. Pack 'em under the arms. They're cheaper than bucillamine too.
"...there were no deaths and four hospitalizations, of which three were from the placebo arm and one from the Bucillamine low dose group (300mg/day)."
Nobody died in the placebo arm either.
Nice try
The trial was never intended for HIGH RISK patients but rather those with MILD TO MODERATE disease....good grief!
The level of pure ignorance displayed by that silly comment truly astounding.
I cant say Im surprised one bit.
For one who literally does nothing except whine ad naseum and cite nothing of remote relevance, you so do pretend to know a lot about whats going on......BULLSHITE!!!
ZERO in the high dose group......learn to read, but then again the omission of pertinent info is likely on purpose.....what a numpt!
Do you know that reducing fever with ibuprofen will improve oxygen saturation?
Cite a study akin to the trial results presented in the buccy trial......you cant because there are none in comparison.
As a supposed ""professional"" you would obviously know that ibuprof was and still is NOT recommended as a widespread treatment for many covid patients due to its interactions and myriad short and long term side effects, as opposed to the tried and now tested Buccy.
What a joke....................
Nothing was talked about regarding high risk patients. I said the excuse of a changing virus was garbage because he had more than enough time to enrol during delta and earlier variants. You said as the trial dragged on they had less chance because of the virus getting weaker. Well no way. That was the most profound statement I have ever heard. He shouldn’t have taken that long in enrolling to begin with. That’s why I said the excuse of a changing virus is stupid. The virus was always going to change. The speed at which they enrolled was the problem.
And how does RVVTF monetize that?! They can’t short of a buyout. They do not have three years and millions of dollars to start fresh for a new study on said symptoms for a virus the majority of the world has moved on from. Hence BP buyout is their only out. And regardless of said symptom relief which comes with time regardless, propping their value up on the heels of a failed trial will not fetch a significant price
Three hospitalizations from placebo and one hospitalization from bucillamine. Maybe MF should trial the placebo. What do you think?
I'm a bedside healthcare professional. Do you know that reducing fever with ibuprofen will improve oxygen saturation?
The unbridled ignorance is palpable.................
75% of the hospitalizations were in the Placebo group based on low dose for Bucillamine and 100% of the hospitalizations were from Placebo in the High dose Bucillamine trials.
data demonstrated that for patients with oxygen saturation <96% at baseline, Bucillamine had a 29.1% improvement over placebo in time to normal oxygen saturation (SpO2)"
Additional analyses of the Study data are ongoing, which could support certain strategic decisions on pursuing the development and commercialization of Bucillamine
Whether the latter analyses bears any fruit remains to be seen but do stop with this nonsensical diatribe.
While you may be able to CONvince some here, there are those who actually "read between the lines" and extract the not so obvious nuggets of info.
I dont have any PROOF, but, the EVIDENCE discerned from past investing experiences, suggests that its primarily agenda driven, as opposed to simply being people with no life goals that revel in the misery of others.
What is behind all of the happiness behind the demise of this stock? Why do some of you enjoy beating people up and seeing others lose money? Everyone is entitled to their opinion whether it's bearish or bullish. This stock will either go back up, be bought by another pharmaceutical or it will tank. Those are the options. Thus is the nature of investing in penny stocks. Email and social media has made it so easy to be nasty to others without suffering the concequences.
"There was no significant overall improvement trend between the Bucillamine and placebo arms for observed clinical symptoms and viral load data."
Enough of your retaliatory BS you insolent little peasant.
I understand how difficult it may be to grasp, hence I will ""dumb"" it down so even you can understand.
Wild Strain/Delta were more VIRULENT as opposed to Omicron and as such the longer the trial dragged on the less likely statsig could ever be achieved because as the data proves, death and hospitalization rates plummeted after the Delta surge and even more into Omicron.
Also, I repeat the point which you CONveniently ignored, the trial cohort EXCLUDED participants who were most likely to die or become hospitalized because of the stringent medicals that those chosen had to undergo.
I was and still am no fan of MF (the critical posts are there) so any reference to his stewardship of Revive is wholly irrelevant, ie your entire post, because I invested because of Buccy, NOT MF.
Exactly, and as such theres EVIDENCE, based on the data and posted studies, that Buccy is effective re symptom relief.
Reading and Comprehension 101 as opposed to the ad naseum windbaggery on display from certain persons with an agenda and/or nothing better to do than post about a stock they dont,or have never owned.
Honestly speaking, how utterly pathetic is that........................
Statistical significance had nothing to do with a changing virus. They had plenty of time to enrol enough patients before omicron came into the picture. The changing virus argument can stop anytime cause it’s not even relevant.
FACT: Medical professionals are driven by evidence based medicine.
You have nothing. If you can’t handle that fact I suggest a GI Joe and a sippy cup.
If you cant handle FACTS I suggest crayons, a picture book and a quiet "safe space".
Obviously this adults only area isnt for you.
Funny how ye never seem to address the cast of losers who come here daily solely to gloat and mock (shite) all over those who "lost big" but yer problem is with my post about self accountability.......what a joke!
#whiners
Agree with the first half of your post. A pity because for the remainder, you come across as a gloating bell-end.
#wanker
The results show no such thing and that very statement literally proves one cant read and, most importantly, COMPREHEND!
The data did not show statsig for the trial objectives ie hospitalizations and death, but did show effectiveness re symptoms, which is why they tried to modify the ep's to symptom relief.
Anyone with two functioning brain cells and a basic understanding of the process saw that the reason for the lack of statsig was due to the evolution of the virus over time to less virulent forms and the fact that virtually all deaths were VERY OLD and VERY SICK people.
The composition of the persons recruited for the Buccy trial were only healthy people so in hindsight the ""death ep"", and to a lesser extent the hospitalization ep, of the trial was dead on arrival from the onset.
The comments here from a bunch of whiners says it all about the utter stupidity on display.....no one is to blame for any losses other than the investor who greedily went all in rather than playing the volatility since 2020.
Problem for the agitators is that those of us who did now own loads of FREE SHARES and as such cant be swayed by the yarn being spun by the ""army"" of planks here......keep posting in vain! lololsss
#bloviatingwindbags
And I’m sure some Greeks still believe in Zeus.
What is to still believe? The data shows its ineffectiveness. It took years to get to that. There’s nowhere else to go save a buyout for a few pennies for a BP pet project who thinks they can roll the dice on another indication years down the road
Gray area hypotheticals are his forte. As I said before he can milk his six figure salary for awhile longer dangling the carrot in front of investors who are in hefty denial until the checks dry up and he has no choice but bankruptcy. Pocketed a few million and can play the “ho hum I tried” card.
Yeah I agree but once again the wording of the PR is strange. It said something like working with interested partners for potential approvals. I take that to mean they have nobody from BP knocking on the door, but who knows with the history of MF's vague PRs.
Our only hope is for Revive to be bought out by BP. MF did make mention of partnering so I have to figure that maybe just maybe we will all get lucky. Why sell now, I lost most of what I invested.
Here’s a post from another message board that lays it out pretty clearly.
“It’s apparent with the recent developments of the bucillamine trial, it is proven that bucillamine is a powerful drug for luring people into the idea that it might be effective against anything to do with breathing. Clinical trials have proven that if you say “it looks as if bucillamine ”or “there might be evidence that bucillamine…” it is a powerful tool for market manipulation. The ability of Bucillamine (alias name of a poster) to put out countless Press Releases, indicates that bucillamine is a powerful tool in the epidemic of ‘pump and dump’ stocks. Bucillamine has proven to be a powerful IP for its CEO and board members to create unlimited hopium for investors. And when 2.0 is added to bucillamine it appears bucillamine can be 2.0 times as effective for bringing in new investors and will extend the life of bucillamine for another year. Who would have thought? Oh… yeah… MF.”
It’s pretty hard to be outraged when you enable and promote the scam.
It’s pretty hard to be outraged when you enable and promote the scam.
LOL. Wrong again. Historically, my charter was to respond to those posters who blatantly bashed / chastised this company and stock without backing it up / quantifying their statements. I am all for negative posts if they are backed up. Dignity doesn't feature here.
I see you are on my blocked list which means I have thought you were a twat for some time now. This has not changed.
#bucillamine
To clarify, I believe in Bucillamine not CEO Michael Frank. You have confused me with another poster when you claim that I have "defended" him (in fact I have done quite the opposite and yes, I am outraged by how he has played his role as CEO). In my last response to your onslaught of bitterness, I meant refrain from such statements as "this goose is cooked" among others of yours - again, some of us Longs still believe in Bucillamine.
You want dignity now after blindly defending this buffoon of a CEO who took your money and the incessant pumpers on here? You should be outraged. You. I. Everyone here are bagholders and need to face reality. MF is now milking a hefty salary on us. Denial
Were you showing dignity when you castrated those who correctly pointed out all the red flags over the years?
Yes I'm 100% calling them out. They have absolutely no criteria that would say it's over because most of them have been practicing nothing but blind faith for 3 years now. They will continue with this delusional behavior because they know nothing else. I'll wait till the grass stops growing and the rivers stop flowing for an answer.
How bitter are you fella? We Longs are all mortified but show some dignity by giving it a rest.
Target all your hatred and despair directly at CEO Michael Frank vs here. His response will be telling after all.
Apparently Michael Franks office chair being auctioned by the bank
Okay…so tell us what objective criteria is required to say the fat lady is singing?
https://www.cidrap.umn.edu/covid-19/common-diabetes-drug-shown-prevent-long-covid
2 year trial 1,200 patients for an effective, available, cheap drug to combat long covid. AKA everything we’ve claimed Bucci is. The work is done. It would be 2024 before a long covid trial even got off the ground for Bucci. This goose is cooked
Disagree wholeheartedly with your claim that the (Bucillamine) show is over. Holding ALL my shares until the fat lady sings (or snuffs it frankly). Too compelling not to.
Shows over folks: Is there a way to prevent long COVID? A new study in the United States found that taking metformin, an affordable first-line Type 2 diabetes drug, shortly after diagnosis of COVID-19 can reduce the risk of developing long COVID by about 41 percent.
Lol been gradually seeing them lol...
always Hoped science of Bucillamine would come through because actually a lot of the chit they say about comapny etc in reddit Is True.
ps. I still Fcking thing even Pax. would of also failed this trial set up if they also only got to 713:)
Yes I always thought he was somewhat right but a Lot lolo...
I use to not like you now maybe ok lol.... godamn thinking u pickels...
but last 2 years been figuring out good people to find other short term investements if I lost money or made... So time to try and make it back. and still holding a lot of shares here. sad there is a handfull of people (that know how good Bucy can Work ...better than the company)can be if given the chance and right trial")
Do they even know Bucillamine like Bmt and Banahow from reddit. read his few days ago facebook chat.....
ps. still holding lol always been bullish on Bucillamine but company lol....
According to CDC data a total of 1.13M people died from covid in the USA so your claim that 1M unvaxxed died from micro clots is provably fabricated bullshite.
The vast majority of deaths in the USA and Worldwide were old people (75+) with 2+ comorbids......thats not an opinion, its a confirmed FACT, and one that many to this day CONveniently ignore.
Not to mention the fact that virtually ZERO of these cases were autopsied so once again your claim is provably false as per usual re this subject.
Now I suggest you look into the ever increasing data thats now providing ample evidence that certain vaxes (ie the mRNA ones) are causing major health issues in the younger healthy persons that were forced/coerced into taking it even though they never really needed them.
Excess deaths in virtually every western country that instituted mass vaccinations is way above the norm prior to covid and there is one common denominator among them all.......no need for me to say since its obvious to everyone paying close attention what that commonality is!!!
I can assure you, based on reality, the unvaxxed arent the majority of persons suddenly dropping dead and whose bodies are filled with enormous clots.
Do however keep shilling BPs and the MSMs bullshite narrative that no one believes anymore.....gudunya!
Finally you come around to face the facts
Yeah and DSA took a lot of crap at times. With these small, clinical stage biotechs management of the trial is just as important as the drug itself, maybe even more so. I can only speak for myself but it was very apparent early on the behavior of MF was that of a rookie amatuer. It was the 800 pound gorilla in the room. Some wanted to talk about it and some wanted to defend him. It would be interesting if we broke those two groups down to see which got burned the worst.
You to ecomike have a good weekend hope your right:) lol but haven't been since when:)
Yes you are correct, and all the toxic positivity spewed by misguided bagholders will not change the hole this company is in. Any company heading for bankruptcy or reverse split/mass dilution has no leverage in buyout negotiations. Revive is a sitting duck.
There is still gap down on the charts at 8 cents. MM's are going to run it back up
LMAO. how " dumb ass management" can MF be if MF is the one making money, and the rest are used car sales folks owning the used cars while telling buyers the used cars they want to sell are POS?
Have a great safe weekend folks. I still own every share of RVVTF I invested in. Ain't over till the fat lady sings.
Oh, BTW, the shorts need to cover, there is a storm coming
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Scientific Rationale of Bucillamine
Preclinical and clinical studies have demonstrated that reactive oxygen species contribute to the destruction and programmed cell death of pulmonary epithelial cells.1 N-acetyl-cysteine (NAC) has been shown to significantly attenuate clinical symptoms in respiratory viral infections in animals and humans, primarily via donation of thiols to restore antioxidant and to reduce the activity of cellular glutathione 2,3,4,5. Bucillamine (N-(mercapto-2-methylpropionyl)-l-cysteine) has a well-known safety profile and is prescribed in the treatment of rheumatoid arthritis in Japan and South Korea for over 30 years. Bucillamine, a cysteine derivative with two thiol groups, has been shown to be 16 times more potent as a thiol donor in vivo than NAC 6. The drug is non-toxic with high cellular permeability. The basis of the clinical study will analyze if Bucillamine has the potential, via restoration of glutathione activity and other anti-inflammatory activity, to lessen the negative consequences of SARS-CoV2 infection in the lungs.
| Psilocin Pharma Corp. has developed production solutions for the active compound Psilocybin. Our process encompassed with our intellectual property cover methods of production of Psilocybin based formulations. Psilocin Pharma Corp’s range of products have been engineered to work synergistically with the body's own natural pathways of absorption while offering a contemporary approach to consumption. Psilocin Pharma also has strong relationships with specific lab partners in certain areas like Brazil, where these formulations are legally approved and plan to sell products in these jurisdictions. | |
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