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Hey, Blue. Good day in Frankfort. Come on, we have to get excited about something. It's a funny way to respond to a letter, agreed, but I think we are finally on the right track.
I firmly believe in Bucillamine’s wider usage but candidly, I now believe little in Michael Frank as a leader to make Revive a success. I seriously hope I am proved wrong and challenge him to ensure I am and others are.
The company intends to follow the same path that was laid out since Sep/Oct 2022!?!?!.....what an absolute shock!!!
Bunch of screeching planks................
Bit of a word salad with multiple directions. Lets just hope they can deliver on SOMETHING
Thought the same. Utilized a PR to throw shade at BMT’s letter and request. Truly incredible
This Vitamin Supplement Linked To 40% Lower Dementia Risk
{take a guess}
It is thought that the vitamin helps clear the brain of the characteristic tangles of proteins that form in dementia.
Taking vitamin D supplement could decrease dementia risk, a large study suggests.
People who took vitamin D supplements lived for longer without developing dementia and overall had a 40 percent lower risk of developing the disease.
Adequate vitamin D levels have been repeatedly linked to lower dementia risk by research ( 1, 2, 3, 4).
One study has even suggested that adequate levels of vitamin D could prevent almost one-in-five cases of dementia ( Navale et al., 2022).
However, the link remains somewhat controversial, with other studies finding no connection (also: Owusu et al., 2018).
Professor Zahinoor Ismail, the study’s first author, acknowledged the contradictory findings from past studies:
“We know that vitamin D has some effects in the brain that could have implications for reducing dementia, however so far, research has yielded conflicting results.
Our findings give key insights into groups who might be specifically targeted for vitamin D supplementation.
Overall, we found evidence to suggest that earlier supplementation might be particularly beneficial, before the onset of cognitive decline.”
Vitamin D and dementiaFor this study, data from over 12,000 participants in the US National Alzheimer’s Coordinating Center was analysed.
Just over one-third were taking vitamin D supplements.
The results showed that vitamin D supplementation was associated with a reduced dementia risk in all groups.
However, the connection was stronger in women and people who had no pre-existing cognitive deficits, such as mild cognitive impairment.
Similarly, carriers of the APOEe4 gene appeared to benefit more from vitamin D supplementation.
The APOEe4 gene significantly increases the risk of developing dementia.
It is thought that vitamin D helps to clear the brain of the characteristic tangles of proteins that form, known as amyloid and tau.
Dr Byron Creese, study co-author, said:
“Preventing dementia or even delaying its onset is vitally important given the growing numbers of people affected.
The link with vitamin D in this study suggests that taking vitamin D supplements may be beneficial in preventing or delaying dementia, but we now need clinical trials to confirm whether this is really the case.
The ongoing VitaMIN D study at the University of Exeter is exploring this issue further by randomly assigning participants to either take vitamin D or placebo and examining changes in memory and thinking tests over time.”
I dig the PR and it is clear MF received the said letter. I hear unblinding and partnership, and I am getting optimistic again.
ps. Let's see.
Yeah, that sounds like a direct shot across the bow to let the "rogue faction" know that Revive is not going to comply with their "demands for answers".
I guess if there is a question that I would want answered from them at this point is if they fully intend to keep their IP and only pursue partnerships, rather than potentially selling it to BP?
But it also sounds like they were trying to be a bit more complete with their information in this last PR.
"At this time, the Company will only provide regular updates via press releases as information becomes available."
This is the first time i've seen this statement in one of Revive's PR. When Biomedical Trader (BMT) sent Revive the letter of questions approximately 5 days ago he stated that he wanted Revive to respond to the questions by the end of business Friday, April 21, 2023.
Because of this latest PR and specifically the "At this time" language in it i have a feeling that Revive (Michael Frank) will forgo providing a non PR response to the letter/questions.
A reminder of the letter...https://www.reddit.com/r/RVVTF/comments/12kpawg/letter_sent_to_the_bod/
Revive Therapeutics Provides Update of Phase 3 Clinical Study for Bucillamine in the Treatment of COVID-19
April 18, 2023 18:44 ET
https://www.globenewswire.com/news-release/2023/04/18/2649628/0/en/Revive-Therapeutics-Provides-Update-of-Phase-3-Clinical-Study-for-Bucillamine-in-the-Treatment-of-COVID-19.html
Informal shareholder meeting
https://www.reddit.com/r/RVVTF/comments/12qmj8o/informal_shareholder_meeting/?sort=controversial
Good move CW :)
I remember Fress selling his 1 million RVVTF shares at around 70 cents in December '21 and then disappearing. Smart man! That's not to say we won't ever hit that (and more) again, but how many shares would $700k buy at today's prices?!!!
Lol. You have an excellent memory, Rubber. She does not really understand the concept of owning stocks. She is still holding it and doesn't quite understand what she owns, but I slipped her $100, so that in case of Armageddon, I still remain her favorite uncle
ps. I saw that Merck bought out a company today for, I believe, 11 billion or some crazy number and I peeked, hoping it to be Revive, but until will unblind, nobody knows the extent that Bucillamine works. Yes, there are lots of studies, but big pharm needs clinical studies.
pps. Release the Beast. #Bucy.
CW. How's that niece of yours who you gifted the RVVTF shares to? I hope she knows not to disown her favorite uncle just yet. There could be a twist to this tale.
There seems to be a lot of empirical evidence of this, since Covid19...And the Need for FDA approval of $RVVTF Bucillamine gets more obvious everyday,
This explains much.
https://scitechdaily.com/covid-19-strikes-again-accelerating-dementia-in-the-most-vulnerable/
Down with the CEO I have 5 million shares. Let's vote! That lying f* dolt. And his dog eo
Hotel
Keep it simple. Communism by any other name.Vast Majority of the population too ignorant to realize their fate. Im buying an island. F them all! Lol
Take care and God bless america!
Everyone has a need to be correct, but it's important to hear both sides to the story so you can make your own decisions based on your own research. Too many people today try to shut down opposing views which really isn't democracy but socialism or marxism. I like hearing from all of you.
Thanks Gator
I hope all is well
Thanks Gator
I hope all is well
I just wonder sometimes how much the company could do with the Psychedelic side if Bucillamine is finally fda approved, if it works as Bmt think and I trust his expert knowledge of how it should work on covid. If they happen to get 300 m or 1b or a little more...
would be a good time for Bucilllamine to help with this Chit :0
https://twitter.com/MLS_Dave/status/1646911946304675847
#Packers QB Aaron Rodgers will be a featured guest in a psychedelic science conference in June called "Psychedelic Science 2023"
— Dov Kleiman (@NFL_DovKleiman) March 9, 2023
It is dubbed "the largest psychedelic gathering in history.", via @TMZ https://t.co/dwFGfbJLDu pic.twitter.com/TlCNqHng7y
Ear plugs work just as well against the noise of glorified pumpers and those who continuously state that it's "time to load" up.
Am I the only one that has noticed that some want to pour gasoline on a claimed to be fire ($RVVTF) and claim they are not with the Government and are here to help?
LMAO
The only thing I see that sticks out like a sore thumb regarding $RVVTF , is loud, obnoxious, worthless claims to be shareholders that want volume to flip shares.
Ear plugs are sound (LOL) science based devices just like $RVVTF Bucillamine.
Ditto, on all of that, and it is $RVVTF time to load IMO, well said.
Thanks - i'm all for a review of leadership - just the first I heard about it. Change of leadership or not and while I know the study is already in motion, the focus needs to not be so much about Covid but an overall conversation (MF did imply that he was going to take this route) with the FDA about usage of Buc in general based on it's history.
things that make me go "hhhmmmmm"--
It’s unclear what BMT can do outside of a proxy vote to oust MF. For some reason MF is a hero to sheep and the sheep will stand by him all the way to trips.
Don't know if the reddit group has openly stated some of these things. But my guess is that BMT and possibly the Dr. Icham dude may have some sway on that.
It seems like they are doing their best to cast down a gauntlet. I think it is fair that some of these CEOs have their feet held to the fire when needed. The sense I get is that they feel they are untouchable when it comes to small OTC companies like this.
so do we know who this committee is that is interviewing / doing a search for a new CEO?
You are right. Revive being down has nothing to do with buccillame. The fact revive is down is due to piss poor management.
I don't think Frank will be surprised by the end part you reference CW. If anything it should place him under appropriate and merited pressure per se. If Frank gets emotional about it, it tells us a lot about him plus it would be him clutching at straws as part of a spineless attempt to disregard the letter.
I like and support this initiative put forth by the Reddit consortium. Frank needs to now stand up and be counted as his silence since early March is totally unacceptable and deeply alarming to most (serious) investors.
GL to us all (although luck is not a strategy of course..)
Yep. The letter idea at first made sense however the questions and comments like you just shared open the door for big disappointment
I do sincerely hope im wrong.
I liked the memo until I read the ending again. This will piss off the big guy and hinder getting a solid response.
If all other avenues have been exhausted, it is time to bring on an executive with relevant experience in the pharmaceutical industry to tap into Bucillamine’s potential. We are in discussions with promising candidates and are prepared to offer a recommendation if an experienced candidate for CEO has not been identified by the board.
Thanks for your response Rickstereo. We will see if any of this comes to fruition.
By Mid 2021, the entire market started and has been in a down trend, while $RVVTF rallied and held up until the whole market went totally south 12 moths ago when the US FED started the panic rug pull to kill inflation, "at any cost"
That is my read on a lot of it. Weeks ago there was an 8 million share dump in minutes, with not bid support, by someone. Stock is already up 100% since then
Not even sure it was legal, unless it was shorts and stop losses triggered.
Folks might might want review the history of penny stocks that made the cut in the Past, like Citi Bank, Apple, GM, Ford, Sirius XM (I bought in 2009 for about 2.5 cents/share) all back in 2009... When the markets were all peak doom and gloom...
Any stock that is not profitable, or has debt, and has market revenue risk has gotten hammered, few have prevailed.
One I bought in 2013 around a penny, made it to Nasdaq weeks ago. Opxs...
Meet one of the top famous shorts, talking about penny stocks that made the big time like Apple and SeriusXm, after a near death crash...
https://www.timothysykes.com/blog/most-successful-penny-stocks-in-history/
There are others that could qualify for inclusion but those listed are, imo, the examples that most clearly apply.
As I've consistently insinuated since 2020......methinks "something is rotten in the state of Denmark"....and IMO it's not being done to benefit retail holders!!!!!!!!
1. Management stops defending the stock price.
Been the norm with rvv since it hit 70s and then continued the spiral to single digits with no apparent concern from mike et al.
2. Social media posts are overly bearish and calling for the CEO’s removal.
I could name quite a few but wont lest ""they"" become triggered and require counseling. lololsss
6. “Sell this, buy that.”
See previous answer
7. Bizarre price action prior to upcoming milestones
Again, other than the run to 70s upon news of the trial, literally every major milestone for rvv has seen a minor pop, which was then followed by a reversion to previous and lower levels. Ask yourself this obvious question.......how was it that there was not even the hint of a run based on pure speculation prior to the fda's latest response!?!?!
10. Your stock has become disconnected from reality
From day one the trading here made no sense, especially when viewed with the perspective that there is voluminous scientific data that supports buccy as being an effective, and arguably superior, treatment for covid and its associated indications.
Good stuff. Thank you.
Biomedical Trader (BMT) has stated that the letter (questions) will be sent tomorrow and will post the letter shortly after sending it.
What's the latest on the Reddit group initiative to have CEO Michael Frank respond to a series of shareholder questions? Anyone?
Obtuse Eye. If you look back at my posts I never took a position on the fda. I admitted my ignorance and didn’t object to others including ric who took the position fda was corrupt or bias to BP. I still feel the same way and remain neutral because I admit not knowing enough to form an opinion one way or the other.
What does bother me is this notion of some who say revive has the great drug worth millions and the same folks say the fda will never approve. I’ve been very vocal about that. And why I don’t invest more in this pos.
Hence I’ve said for months if this is the case then it’s MFs responsibility to unlock shareholder value thru some partnership with a BP. I suppose we wait and see. It’s outcome #4 from the last PR. For my part I have doubts about the drug but that’s because of the pps and poor results with FDA process make it unlikely a partnership will emerge. Thankfully I’m only out about 1200 on paper actually a little less since the flip I did a couple weeks back
Of course I hope I’m wrong about the drug and ability to partner.
Great find! I think there are a fair amount here that are not surprised by what is in the article.
It even goes on to point out that the FDA was asked about when they knew of the shortcomings. *SURPRISE*, no answer.
It seems this was a heist from the outset. The kingmakers already knew where the approvals, and the money were going to flow to.
So every company that received EUA for a vaccine have all now been identified in some sort of chicanery in which they either covered of data that would be damning to their materials, or straight lied in order to get their items through. Despite being uncovered, there is NO ONE going to jail, or NO ONE being held accountable.
If anything, any one that so much as calls it out are being discredited, or the information is being glossed over as if it was no big deal.
@govprs, at some point you can acknowledge that there is foul play when it comes to Big PHerm, I mean Big Werm, I mean Big Pharm, and the FDA. ~Sounds like a 70's tv show "B.J. McKay and his best friend Bear".
Totally agree Rick! I found this on twitter. Those of you with more experience than me would know if it is accurate.
https://www.griproom.com/fun/10-signs-your-company-is-about-to-be-acquired?fbclid=IwAR3JTUCwuTKGzupmz1CmHdyi0OyHgcMJB41A0ksrCTLShT2cVnU3PW5U9TI
I've never subscribed to rics pov. Rather I find him as negative as they come
This statement is absolutely mind boggling when one closely examines the source from which it emanated.
IT literally slinks on here to gloat about, and most obviously, gleefully mock those who may have/have experienced monumental losses over the past weeks/months.
#scumbag
Reposted because citing facts that exposed ones weak narrative as being utter bs is inCONvenient.......................
but when there are millions of people testing positive daily and you still can’t enrol 1000 that is on management for not staying on pharm olam.
If only mikey boy had simply screamed at and threatened PharmO daily for only Locating, Testing and then Inviting 700+ persons that fit their stringent qualifying criteria to participate from the overall limited subset of patients, and locations (~47) in ~1.5 yrs (Jan 21-Aug 22), all accomplished while being constrained by limited resource$, they would have surely gotten the additional ~250 persons just to make some alleged SHAREHOLDER that posts gibberish here daily content.
Example of "'logic"" from a muppet.................lololsss
Cool- You're one of my favorite posters. You always find unique and relative items. Now if you can please find a path to recoup some of our loses, the longs will be much obliged.
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Scientific Rationale of Bucillamine
Preclinical and clinical studies have demonstrated that reactive oxygen species contribute to the destruction and programmed cell death of pulmonary epithelial cells.1 N-acetyl-cysteine (NAC) has been shown to significantly attenuate clinical symptoms in respiratory viral infections in animals and humans, primarily via donation of thiols to restore antioxidant and to reduce the activity of cellular glutathione 2,3,4,5. Bucillamine (N-(mercapto-2-methylpropionyl)-l-cysteine) has a well-known safety profile and is prescribed in the treatment of rheumatoid arthritis in Japan and South Korea for over 30 years. Bucillamine, a cysteine derivative with two thiol groups, has been shown to be 16 times more potent as a thiol donor in vivo than NAC 6. The drug is non-toxic with high cellular permeability. The basis of the clinical study will analyze if Bucillamine has the potential, via restoration of glutathione activity and other anti-inflammatory activity, to lessen the negative consequences of SARS-CoV2 infection in the lungs.
| Psilocin Pharma Corp. has developed production solutions for the active compound Psilocybin. Our process encompassed with our intellectual property cover methods of production of Psilocybin based formulations. Psilocin Pharma Corp’s range of products have been engineered to work synergistically with the body's own natural pathways of absorption while offering a contemporary approach to consumption. Psilocin Pharma also has strong relationships with specific lab partners in certain areas like Brazil, where these formulations are legally approved and plan to sell products in these jurisdictions. | |
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