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I've never subscribed to rics pov. Rather I find him as negative as they come
This statement is absolutely mind boggling when one closely examines the source from which it emanated.
IT literally slinks on here to gloat about, and most obviously, gleefully mock those who may have/have experienced monumental losses over the past weeks/months.
#scumbag
Reposted because citing facts that exposed ones weak narrative as being utter bs is inCONvenient.......................
but when there are millions of people testing positive daily and you still can’t enrol 1000 that is on management for not staying on pharm olam.
If only mikey boy had simply screamed at and threatened PharmO daily for only Locating, Testing and then Inviting 700+ persons that fit their stringent qualifying criteria to participate from the overall limited subset of patients, and locations (~47) in ~1.5 yrs (Jan 21-Aug 22), all accomplished while being constrained by limited resource$, they would have surely gotten the additional ~250 persons just to make some alleged SHAREHOLDER that posts gibberish here daily content.
Example of "'logic"" from a muppet.................lololsss
Cool- You're one of my favorite posters. You always find unique and relative items. Now if you can please find a path to recoup some of our loses, the longs will be much obliged.
Pfizer Caught Covering Up Data on Waning Immunity
https://slaynews.com/news/pfizer-caught-covering-up-data-waning-immunity/?utm_source=mailpoet&utm_medium=email&utm_campaign=daily-newsletter
Oh God that is horrible!
I guess that is a nice, easy, simple-minded way to approach this. You can keep on that train of thought.
I think most of us still hold out hope that it will manifest into something tangible. Sadly though, if the President is going to declare the "COVID emergency" officially over, it lessens the urgency at which this will get looked at with real meaning.
So many of us wonder, how truthful was the process all along? It seems pretty clear what side you take on this, your name kinda spells it out. But as Rick has stated, if you choose to look past the practices as we've seen them play out, and then believe that RVV got that same treatment or have not progressed solely because of something they did/didn't do. That is why you're meeting the resistance in opinion.
I never said it was open to everyone but when there are millions of people testing positive daily and you still can’t enrol 1000 that is on management for not staying on pharm olam. It’s not like he can just hire someone and forget about it. He is the ceo. He takes responsibility for everything with the trial. He isn’t getting paid $30k a month to sit around. And why post the starting and estimated completion dates? The completion date has been pushed back 6 times because of how terrible frank has been.
Some FACTS about the trial for the clearly uninformed, ie, a "chocolaty muppet"...................
ClinicalTrials.gov Identifier: NCT04504734
Recruitment Status : Enrolling by invitation
First Posted : August 7, 2020
Last Update Posted : October 27, 2022
Enrolling by invitation: The study is selecting its participants from a population, or group of people, decided on by the researchers in advance.These studies are not open to everyone who meets the eligibility criteria but only to people in that particular population, who are specifically invited to participate.
Actual Study Start Date : November 27, 2020
Estimated Primary Completion Date : December 31, 2022
Estimated Study Completion Date : December 31, 2022
Repeating the same asinine statement ad nauseam about mike intervening only proves how fake the entire premise is, especially when viewed in terms of the hard facts above.......which you never produce.
What a jester! lololsss
@govprs......Wow so many got shammed here. Terrible outcome for heavy bag holders
Ye may have better luck selling this "snake oil" if ye put a little more effort in, instead of making the same inane pitch daily!
Just some food for thought there boyo.....................
Again you keep talking about a changing virus. Yes it changed in early 2022 which still gave the company over a year to get the required patients including in the time of delta which was the worst variant. So you can stop with the changing virus bs. It was up to frank to stay on pharm olam to get the required patients and he didn’t which is why we are here. If you get the required patients in delta this trial is long done and likely we all would have gotten paid.
So this .05 stock will remain a .05 stock because of the fda no matter what??
Wow so many got shammed here. Terrible outcome for heavy bag holders
Yet another response filled with such nonsensical and false drivel that Im aghast that anyone posting here daily with this pseudo ""authority"" could be so uninformed.
Yes let’s keep blaming the fda and using that as an excuse for franks terrible job with this company.
I absolutely do because of numerous examples of CORRUPTION and blatantly selective application of the rules/guidelines, ie, if there was a level playing field, rvv would likely not be in this current predicament. Only those blinded by bias and/or ignorance would claim that the fda doesnt play favorites with a certain "elite" group.
They had more than enough time to enrol the 1000 patients before everything changed.
Yes PharmO had enough time and why they couldnt achieve that goal only they and mike can answer but I suspect it had to do with them noticing the ever changing landscape of the virus, among other factors. However, the fact remains that even if they did complete the 1000 patients, based on fda requirements in 2023, IT WOULD STILL BE REJECTED because the trial did not contain the required data ......this basic fact exposes the utter stupidity of your entire argument.
At this point mike could simply "throw the dice" and go with only the 700+ data and request that the dsmb unblind and decide whether it shows statsig based on the old ep's.....this path was pr'ed months ago by rvv and was based on the ep request being rejected by the fda so maybe the "doom and gloom" crowd should try reading a bit more......remember this!?!....of course ye dont!......................
From an Oct 2022 Pr......................
Should the FDA agree with the revised protocol, the Data Safety Monitoring Board (“DSMB”) will review the completed Post-Dose selection data of approximately 500 subjects in the context of the new primary endpoint. The DSMB may recommend continuing the Study if there is a trend toward achieving statistical significance, halting the Study early due to statistical significance likely not going to be met, or halting the Study early due to positive efficacy showing statistical significance. Regardless of the outcome, the Company would proceed to seek a meeting with the FDA to agree on a proposed plan for potential regulatory approval.
Instead of talking about the fda being corrupt maybe look at how stupid Frank was to go with an endpoint that the fda said not to.
The trial ep's were set in 2020 and agreed to by the fda/dsmb........the fda rejected the pcr standard in 2022 because it was unreliable for assessing ep's in 2022, and they later requested ep data that the original trial, WHICH THEY AGREED TO, did not possess.
Buccy has proven itself to be truly Safe & Effective for over 30 yrs and the fact that SAFETY is the #1 issue re approving a drug, one can only wonder why the fda appears to be delaying the scrutiny of the scrubbed patient data by the DSMB!?!?
Simply allow the evaluation of the 700 data so that it can either be accepted or rejected due to lack of efficacy.......everyone can make up their own minds whether there are ulterior motives at play here or not.
#shills
IMO he will never reply back
My understanding is that he replied that he will answer questions so BMT et al. is compiling a list of questions and prioritizing them based on the number of responses they receive from investors.
Response received for presentation request
https://www.reddit.com/r/RVVTF/comments/12bnva8/response_received_for_presentation_request/
What happened with the letter to CEO? Did he reply back ?
And the ceo was supposed to do what exactly counter top?.....go out and recruit patients for PharmO himself, or maybe fire them and start over fresh a yr+ into the trial?
Phase 3 trials usually took several yrs to complete and since the covid urgency has now greatly abated the fda seems to be reverting back to the old system, except when BP comes calling of course.
The path of the pandemic was constantly changing and as such getting the trial done after this latest shenanigan from the fda entirely moots your suggestion.
The sole issue at this point is the fda playing games with the requirements and as such this is what needs to be directly addressed.....nothing more!!!
2 babies born with brain damage after moms tested positive for COVID-19 during pregnancy, study reveals
By Patrick Reilly
April 7, 2023 9:21pm Updated
Loving mother looking at her newborn in an incubator
Both babies suffered seizures after being born and later suffered significant developmental delays. One died at 13 months while the other was placed in hospice care.
The first confirmed cases of babies born with brain damage as a result of the COVID-19 virus crossing into their mothers’ placenta were revealed in a new study this week.
Both babies were born to young mothers who had tested positive for the virus in their second trimester during the peak spread of the Delta variant in 2021 — before vaccines were available, according to the University of Miami study that was published in the journal Pediatrics.
On the day they were born, both babies suffered seizures and later suffered significant developmental delays. One child died at 13 months while the other was placed in hospice care, researchers said.
The babies did not test positive for the virus themselves, but had high levels of COVID antibodies in their blood, said Dr. Merline Benny, a neonatologist and assistant professor of pediatrics at the university, according to NBC News.
She said this indicates the virus likely transferred from mother to placenta and then to the baby.
The research team located evidence of the virus in both mothers’ placentas, according to Benny. An autopsy showed traces of COVID-19 in the baby’s brain, suggesting direct infection caused the injuries, she said.
Both mothers tested positive for the virus. One had only mild symptoms and carried the baby to full-term, while the other mother was so severely sick that doctors had to deliver her baby at 32 weeks.
Both babies suffered seizures the day they were born and suffered severe developmental disabilities, researchers said.
Doctors had suggested this is possible, but this study is the first direct evidence of the virus in a mother’s placenta or an infant’s brain, researchers said.
Other viruses have been known to cause brain damage to a fetus, including Cytomegalovirus, Rubella, HIV and Zika, according to NBC.
“This is the first time that we’ve been able to demonstrate the virus in a fetal organ with transplacental passage,” said Dr. Michael Paidas, chair of obstetrics and gynecology at the University of Miami. “That’s why we think this is so important.”
While cases like this are suspected to be rare, Dr. Shahnaz Duara, an obstetrician and gynecologist at the university, told NBC News that women who were infected with COVID-19 during their pregnancies should contact their child’s pediatrician to look out for developmental delays, which could take years to manifest.
“We know that things can be fairly subtle up to 7 or 8 years of age until kids go to school,” she added.
He went on vacation after he got investor’s to pony up 4.3mil at .15 a share
So the ceo just goes on vacation after getting pharm olam? Is still his job to stay on top of this and get the trial done. It’s his job as the head of the company to make sure things are getting done which he did not do. Time for him to leave. Those who voted to keep him in at the last meeting are getting what they deserve.
Comparing an FDA Phase III drug trial in a pandemic, hired contractor to set up and manage the Phase III trial, to a Plumbing contractor on a house is the dumbest thing I have read yet.
Go RVTTF go
This is a Double Blinded Placebo Controlled Trial, ie the GOLD STANDARD of clinical trials, so anyone who thinks that the ceo of a company has a say in how the trial is designed, implemented and conducted is a dullard.
The very purpose of the stringent protocols is to ensure that the entire process is isolated and free of biased outside influences, especially from the ceo of the company who stands to benefit hugely if its successful.
I already stated, but apparently someone cant read, the trial was designed based on the requirements at the time, ie hospitalizations and deaths but as time progressed the virus changed and so did the protocols......WHICH VIRTUALLY NO ONE FORESAW!!!
The fda has its agenda (serving BP) because they apply their requirements conveniently as i previously mentioned re the "8 mice trial" so how anyone is expected to take those clowns seriously is beyond me.
Now do continue shilling for whomever and making a complete arse of yourself as ye continue to post this ignorant drivel thats devoid of the most basic facts.
@Pennyworld...................
Pharm Olam as I see is no fly by night outfit since theyve been in operation for 20+ years, so even though they may not be a large Top Tier outfit such as those used by BP, they arent the worst either.
That said this IMO has less to do with Pharm Olam and more to do with the fda having rwo sets of rules, ie, one for BP where they can literally lie, fudge their data and still have their crap drugs rubber stamped for universal use, AND, another set for everyone else that gets scrutinized top down, which usually means a longer, tougher and delayed path to approval.
He runs the company and hired these people. It’s his job to stay on them to get the trial done. If you are a contractor building a house and the plumber is taking a year to finish the bathroom what do you do? Just say “oh well not my fault”? No, you ask him what is going on and tell him to get the job done now or screw off. Frank hires these people so it’s on him if things don’t work. So making excuses for his screwups.
Rick.. one could argue that Mike may have hired the wrong outfit to conduct the trial. He may have been trying to safe $$. This is exactly what RLFTF did. They hired an outfit that bungled everything up on the end-points.
Only an idiot with no experience tries to run a phase 3 trial. He could have hired someone but instead was too arrogant thinking he could do it.
Mike didnt "RUN" anything jester......it was Pharn Olam that was hired to conduct and oversee all aspects of the trial.
This info is so basic and yet ye still got it all wrong, therefore the only complete idiot was the joker that posted this garbage, and that would be...........................................
My previous post were questions posed to demonstrate how silly the complaining about mike thats being done here is but ye obviously missed the context, as usual!
I don't consider myself a "talking head", but I will own what I say and what I believe.
With regards to the FDA being corrupt, they are a government run entity. They have already had to admit to taking short cuts, and/or plain and simply not doing their jobs what was one of the most significant things to come through their office in the past 3 years.
With that, I have not said they are "never" going to give RVV the approval. But, I did say that they are going to look out for Big Pharm. You know...the ones who can grease their pockets the most?! If that means moving the goal line, changing the game, etc...
When BP went to them and said, "we have this...", they jumped and said, "Okay! Go ahead and give it out". There was no thorough testing, etc...
But when RVV went to them and said, "We have this...30+ year old remedy" the FDA said, "Wait! Did you test this condition? Did you shake the tree just the way we told you?" When Revive said, "Yes! Here is the proof." They said, "Okay! Let's set up a meeting 3-4 months from now to review." When the 3-4 months passed (2 or 3 times), they said "Oh! The virus has changed, and we're looking for your stuff to do ZYX, not the XYZ that you wanted to show us. Can you show us ZYX?!"
In the meantime, I see those Paxlovid commercials LEFT AND RIGHT!
It`s far from over lets hope something can still get $RVVTF a win..............For the past several months, Omicron subvariants BA.4 and BA.5 have dominated COVID-19 cases in the U.S. But now, there’s a class of new COVID subvariants on the rise and one in particular is getting plenty of attention. It’s called XBB—or Gryphon—and there’s a chance it could overtake everything else out there.
If Bucillamine is as good as we hope maybe it can help with this too........CEO of Carolina Blood and Cancer Care Associates, Dr. Kashyap Patel, believes that the COVID-19 virus not only affected cancer treatment in recent years, but may have also affected the development of “cancer itself.”.....In recent years, Patel has treated several patients in his Rock Hill, South Carolina, clinic who suffer from a rare cancer called cholangiocarcinoma. A number of the patients began developing the cancer 20 to 30 years earlier than the standard age.
Cholangiocarcinoma normally begins forming within the human body around 65 years or older. In the past year alone, Patel’s clinic had seen seven patients diagnosed with the cancer at much younger ages.
Govprs - Did you sign the request for a presentation from Revive Therapeutics? If you have, it would be a good opportunity to address your concerns directly to MF.
But the talking heads, bmt, tix etc all state FDA is corrupt and never gonna give a tiny rvv the approval.
Most ceos would do what’s in the best interests of stockholders. I snoop and others believe MF could do more for shareholders by licensing to BP and monetize this asset. Most bag holders here many proclaimed to be here 2-3 yrs are growing tired and want to monetize the shares they hold. I don’t MF dragging this out longer for a bigger return is what investors want.
What BMTs letter to MF? Bet he ignores it or says no thank you to an investor call
All this makes it more doubtful we have a drug that works. My opinion only
More importantly does MF have a position in rvvtf? How many shares does he own? Did he participate in the offering at .15/share just 8 weeks ago?
How in the F are you trying to still compare a tiny no revenue biotech penny stock firm to the Duponts and Apples of the world?!
How does this:
This is not the place to ask that question the Canadian filings are, but one that knows how to do real DD would have done the DD in the filings not here.
Dow, DuPont, Amazon, Apple, ... none of their CEOs hold shareholders hands 365/year. So you are saying they are not professional? All people get from them is a 4 filings a year and after the fact 8-K event notices.
I too have worked for public companies, going back 48+ years, and when there is Major deal brewing with a mega billion dollar firm even the flies and blinded and silenced and the CEOs are gagged.... until the NDA and deals allow a deal/news release, and even then I have seen international law firms dag shit out so long the stock got clobbered by the silence. In one case the silence was worth it.. They were closing a world wide deal with a 14 Billion dollar firm 10 years ago. Not even light leaked out on that deal for 9 months.
It was very painful. But it was what Alstom Power (Later bought part of by GE).
LMAbsoluteFAO @ “I think we should thank the CEO for trying” !!!!!!!!
WTF……………
I think shareholders are looking for more than just a CEO trying. Thanks may be appropriate if RVVTF achieves its goals, gets FDA approvals, provides a positive ROI to shareholders, etc.
“If any thing we should be thanking the CEO for trying”
In answer to your $RVVTF question:
Interesting. How does this help RVVTF shareholders?
Please elaborate and include how shareholders may have benefited. Thank you
“What MF has pulled off so far the last 3 years, is historical in nature.”
And potentially a fraud. I still can’t figure out if the drug was so good why he wouldn’t license to a BP?
Does MF actually own shares in rvvtf?
Good to know. I'd like to see exactly what the plan is as Revive moves forward. All I know is I paid a lot of money to see the trial unblinded by now and I still wait.
There trying to get last digit pump and dump. MF was just pumping and dumping and this article came out what a joke! MF should be though in jail pumping and dumbing the stock. But SE C don't care. Wait till they start being charged with crypto. LOL
Disagree it is professional. Addressing shareholder sentiment and sharing the strategy/ action plan moving forward is not illegal. I have worked for public companies. IMO mf is an amateur.
Did you notice that the article was "received" back in August 2022? It was accepted 8 months after it was received. Even then it was published nearly 3 weeks after being accepted.
This is definitely great information. But it is either so insignificant to someone that it didn't merit being published a whole 8 months after it was written, or it was significant enough that someone didn't want it published.
Am I missing something? Feel free to correct me if my deduction is wrong.
It’s franks greed that got in the way of this company being successful. Only an idiot with no experience tries to run a phase 3 trial. He could have hired someone but instead was too arrogant thinking he could do it. The fact people still can’t see that after the last 3 years is ridiculous. Open your eyes.
.....a little knowledge is a dangerous thing. It's very naive to think you know what is going on behind closed doors in any company. It's all conjecture so do whatever research you can to make yourself comfortable with your investment. It's simple, if you aren't sell and find another company you feel safe with....good luck!
You're a poet and you didn't even know it.
Dark Chocolate is bitter
White should be sweet
RVVTF ain't over yet
Say "NO" to de feet.
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Scientific Rationale of Bucillamine
Preclinical and clinical studies have demonstrated that reactive oxygen species contribute to the destruction and programmed cell death of pulmonary epithelial cells.1 N-acetyl-cysteine (NAC) has been shown to significantly attenuate clinical symptoms in respiratory viral infections in animals and humans, primarily via donation of thiols to restore antioxidant and to reduce the activity of cellular glutathione 2,3,4,5. Bucillamine (N-(mercapto-2-methylpropionyl)-l-cysteine) has a well-known safety profile and is prescribed in the treatment of rheumatoid arthritis in Japan and South Korea for over 30 years. Bucillamine, a cysteine derivative with two thiol groups, has been shown to be 16 times more potent as a thiol donor in vivo than NAC 6. The drug is non-toxic with high cellular permeability. The basis of the clinical study will analyze if Bucillamine has the potential, via restoration of glutathione activity and other anti-inflammatory activity, to lessen the negative consequences of SARS-CoV2 infection in the lungs.
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