Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
CW
And they just keep churning out the commercials. They have no shame.
Wouldnt hurt to hear something.....how much worse can it get right now.At least some kind of time line......is it a couple weeks away or a couple months away.......for me it dont really matter Im not selling anything I will just hang on....I could sell and get back $21,000 of my $60,000 but right now in my life that $21,000 aint going to change much for me....worth the wait and see.
I don't believe that is too much to ask.
What difference will it make.
CEO Michael Frank, please address shareholders in a personalized note. Firmly believe this is wise and merited at this point. Many of us long term once continue to place considerable faith in you and are holding on with vast paper losses. Time-sensitive at this point I would say. Please give us at least a ‘team pep talk’.
Who else from the investor side agrees hearing from MF is more than appropriate at this time?
Been invested for over 2 years and so far after all this waiting I lost 2/3’s of my money. So sad to see something with so much promise not get recognized. I blame it on BP and FDA, GLTU!
It’s unfortunate no doubt. We need MF to consider his responsibility to shareholders which I don’t see evidence of yet
If the drug really works like the pumps say why not partner?? Think how many millions would be made in such a scenario
If we sitting in the same spot 6 months from now a nickel might be too optimistic
All my opinion only
It would be nice if BP would stop being so greedy....there is enough for everyone,this is never going away
lets hope our data is great and we can start moving up................Coronavirus Mutates To Escape Immune System
The virus often mutates by simply deleting small pieces of its genetic code. The mutations "disguise" the virus from antibodies
Your nickel prediction may come sooner than getting back to double digits. Such a shame. I hate losing money!
Dr Boulware thinks pax. Is only useful for high risk elderly or immunocompromised
likely near zero benefit if vaccinated/survived prior infection.
So what's my overall take away?#Paxlovid is useful for high risk elderly or immunocompromised.
— David Boulware, MD MPH (@boulware_dr) March 16, 2023
Actual absolute high risk, not the CDC basket of higher relative risk.
If age <60yo and with a normal immune system, likely near zero benefit if vaccinated/survived prior infection.
So Pfizer can put out a crap product and make billions in profit,while we sit here with
one of the best product to help people and keep getting pushed back.Maybe they were
waiting to put this report out before letting us fly......maybe Pfizer will buy us out and
label bucillamine as Paxlovid.
p.s Thought Pfizer said it was 90% effective......seen this - In its initial clinical trials, Paxlovid was nearly 90% effective at preventing hospital stays or death due to COVID-19 in high-risk people. Other studies suggest that the benefits of Paxlovid are especially evident for older adults.Feb 6, 2023
Stop the bleeding...give us something to hang our hats on. I can't keep dumping money in this penny stock, need something more to go on. Being down 73% is tough to swallow.
but at least it's 50% more likely to keep you out off the hospital (3 for pax vs 7 with placebo).
For those who haven't seen the numbers: It makes you worse.
#Paxlovid effect on reducing #COVID19 hospitalizations in vaccinated population finally revealed to the public by FDA. #IDTwitter 0.9% (3/317) paxlovid vs. 2.2% (7/314) placebo
Here's to hoping for some dollars for you and a treatment for your sister.
Rubber.....It would be great to have a product that really works. My sister is still dealing with some of the long covid stuff...fatigue,smell,tingling. Lets hope this can cross the finish line.
What I have is more of an annoyance than anything. A significant decline in fitness level from one year to the next that begs the question of "is this more than just aging"?
Doc tells me many of her patients have experienced similar since covid, with chest x-rays showing lung scarring that looks like "crushed glass".
There's a few of us hoping to make some cash out of our RVVTF investment, but there are countless more people out there whose health may have a shot at improving if Bucillamine proves to be a winner
Good luck to all!
Rubber....Sorry you have to deal with all that,hope they get "B" out to the public as I would like to try it for RA. We are going to see alot of other things pop up with the long covid.
Sorry to hear that Rubber. I trust, if we can get thing this to market, your problems will be lessened.
ps. I don't know if Bucy can help with your mother in law, though.
GLTA.
ps. Someday, somewhere, something soon will happen.
That's bizarre. It's well over a year since my infection. I still have constant rushing in my ears, reduced lung function/energy, and difficulty grabbing bits of information from my brain at times. Blood tests from my last two Annual medicals indicate my liver shows signs of damage that is inconsistent with my lifestyle.
This new study would explain why the mother in law slaps me every Friday night.
A odd long covid symptom - It's not clear how many people have developed face blindness after having COVID-19. But the woman, whom researchers identified only as "Annie" to protect her privacy, was one of more than 50 long COVID patients who reported to Dartmouth College researchers in a new study they were having trouble identifying faces after their infection.
I also saw that claim being made re the placebo group but I chose to verify whether it was true or not, found it wasnt, instead of pointlessly ranting about it.
My confidence in rvv isnt based on claims made by random anonymous posters online....but you do you!
Eco
Well I'll tell you what. The folks that got shingles would really wished that they got the vaccine! And probably the level of the shingles virus in the vaccine was to prep the immune system to produce antibodies to fight the bitch. I know folks that got it on their bodies and it is completely debilitating to the max!!
100% go Buci@
From a discussion on Reddit...
From Revive's patent from March 16th, 2021: "Preliminary indications are that none of the patients receiving Bucillamine in the trial have to date been hospitalised for COVID-19 or have died from COVID-19."
https://www.reddit.com/r/RVVTF/comments/r9ug7u/from_revives_patent_from_march_16th_2021/
However, there's no mention about the 1 placebo death or placebo hospital admissions.
You going to show us where you got the information about the 1 death and multiple icu admissions in the placebo group?
The so called news media is not so much corrupt, as it is devoid of science journalists, in part because the so called watchers of the news media click bait news, 99+% have no real educations in science fields, and would not understand any of it. kind of like like the day day trading flip it market place, cesspool these stocks trade in...
The so called Shingles Vaccine is know to actually cause shingles. Google it,
I 100% agree "We have a winner here." $RVVTF
LOL, well I'll be a suck egg Mule, there it is, or part of it. I was going to charge $$$ for it, oh well.., at least it was fun letting the battle drag on claiming I made it up, while it lasted, so now they need to find other BS mud to toss to try and push the stock price down.
"'final thoughts' where it says 'since we had 140 patients taking bucillamine and none of them were hospitalized or died of COVID'.
https://www.reddit.com/r/RVVTF/comments/ritbjd/where_we_stand_on_the_trial/"
LOL, Zelle me the first 1/2, $250 and I will post it.
Hint, the 210 person DSMB review/data was allowed to opened by special request to the FDA, last year, to enable submitting of a request for a possible end points change, and possible ending of adding new people to the trial, which is in the RVVTF public reporting, filings, PRs. tweets in compliance will all Canadian and US regulator rules. So it was unmasked because the FDA approved the RVVTF request for permission.
Rather that waiting for me to reply, I suggest reading and search the known DD already here and in company filings and discussions, on reddit, here and CEO tweets... etc.
I do my own DD - anyone that relies on info posted on a board isn't being real smart. I do pay attention to what folks are saying here, but don't use it as gospel for my decisions.
Even the reddit post I provided to you is only a post. Do with it what you want. Folks that have truly been around for a couple years already know where I stand - no need to either trash talk or thump my chest here.
I have looked at all dd. I have been around here longer than most and never once read anything about the death or icu admissions. We all know about what was in the patent. If you are an actual investor I would think you would also want to see this information and not just believe what some pumper says.
A few weeks ago you were cheering potential results on, only to lambaste the stock when the latest update came out. Even to the point of calling for .05, trying to put words in others’ posts, and calling people out to try and bet against them. What is the purpose?
We can wait patiently and encourage each other on without the help you’ve given to this point.
Ok, Michael Frank. The ball has been passed back to your hands. Take your time to cross your t's and dot your i's. Give the FDA exactly what they want, and put a bow on it. The FDA is not keeping us around because they are nice guys. Clearly, the data is amazing and the unblinding of the next 500 at higher doses will be even better. At this point, all resources and efforts need to be put into this venture. When the new endpoints are submitted, then you may play golf. Until that time, ten hour days with thirty minutes for lunch is all I can give you. Let's make this happen.
This isn't official data / link you're looking for, but it as analysis frorm BMT - I could try to go back farther, but I'm not in the habit of spoon feeding folks - maybe spend a bit of time andd you'll find the data you're looking for, take a look at the last line of the paragraph before 'final thoughts' where it says 'since we had 140 patients taking bucillamine and none of them were hospitalized or died of COVID'.
https://www.reddit.com/r/RVVTF/comments/ritbjd/where_we_stand_on_the_trial/
With the new eyes coming in here I’m sure they would benefit from seeing the data showing one death and multiple icu hospitalizations in the placebo arm. You should find that and post it. You said in the one post it was from the dsmb reviews but that can’t be true because that data is blinded and whoever releases it is going to get fired. What you are saying isn’t adding up. The fact you charge $500 for dd is concerning if you can’t even provide proof to back up your claims.
Eco
Your last paragraph is imo.probably the most important to all the shot and booster recipients who will without a doubt be candidates for minor and major blood clotting. This has already killed too many for the corrupt media to acknowledge.
And PLEASE stop referring to the experimental shot(jab)as a vaccine. PLEASE!
IF YOU RECEIVE THE POLIO VACCINE IT PREVENTS POLIO. IF YOU GET A FLU VACCINE IT PREVENTS YOU FROM.GETTING THE FLU. IT YOU GET THE SHINGLE VACCINE IT PREVENTS YOU FROM GETTING SHINGLES. THANK GOD!
We have a winner here. Thats why I have xxx,xxx shares and am buying more.
Seems like you have to play the "No lowballs, I know what I got" card with these people.
Great job today folks, RVVTF is now luucky #7 on the break out boards, New eyes coming here the rest of the day and evening, lets keep posting facts and DD and explaining all about the gem we have here that is about to Go To $$s/share once the FDA approves the RVVTF antiviral Bucillamine...
Not the first time, and the common trick is to try and knee cap retail by paying a hedge fund to short the stock and at the same time hire a social media fake news squad to spread false information about the CEO, the tech, the chances of approval, the value, all to try and force a sell out cheap.
All we need to do is rally retail and explain the facts. Buy has not been this cheap in ages, and we are 2.5 years closer to FDA approval of potential Multi-billion dollar antiviral drug
I am an investor in many stocks, in new technology, start ups and in RVVTF.
Pressure on shorts and illegal naked shorts to cover will not go away, as the stock continues to rally. Time to cover and buy.
Time for shorts to pucker up, and go long.
Time to review what we know. For starters:
" Revive Therapeutics Announces Publication of Research Data with Bucillamine in COVID-19
TORONTO, Canada -- April 18, 2022 -- InvestorsHub NewsWire -- Revive Therapeutics Ltd. ("Revive" or the "Company") (OTCQB: RVVTF) (CSE: RVV) (FRANKFURT:31R), a specialty life sciences company focused on the research and development of therapeutics for medical needs and rare disorders, today announced the publication of a scientific article evaluating the impact of medication, including Bucillamine, on antibody response to SARS-CoV-2 mRNA vaccines in Japanese patients with rheumatic diseases. The article titled, "Antibody Response to SARS-CoV-2 mRNA Vaccines in Patients with Rheumatic Diseases in Japan: Interim Analysis of a Multicenter Cohort Study", is published in Modern Rheumatology and can be found here.
The article described that antibody levels were significantly lower in the groups treated with TNF inhibitor (TNFi) with methotrexate (MTX), abatacept, mycophenolate mofetil (MMF), MMF or mizoribine (MMF/MZR) combined with calcineurin inhibitor (CNI), and rituximab or cyclophosphamide (RTX/CPA) compared with those treated with sulfasalazine and/or bucillamine or CNI (p<0.01). The newly published study further validates the potential of Bucillamine in the treatment course for COVID-19.
Bucillamine, an oral drug with anti-inflammatory and antiviral properties, is currently being evaluated in a Phase 3 clinical trial (the "Study") (NCT04504734) in patients with mild to moderate COVID-19. The Company intends to seek U.S. Food & Drug Administration ("FDA") Emergency Use Authorization.
"The potential of Bucillamine for COVID-19 is evident with its anti-inflammatory and antiviral properties and its potential use in patients who have taken SARS-CoV-2 mRNA vaccines," said Michael Frank, CEO of Revive....
Fun Fact nearly 300 Billion dollar Novartis drug firm started out targeting the same Market $RVVTF is targeting "a specialty life sciences company focused on the research and development of therapeutics for medical needs and rare disorders"
$RVVTF had Bucillamine already and jumped into the EUA-FDA trials for Covid19.
They are just about the only really promising new Covid19 drug left in FDA Trials and the FDA is acting happy to work with and modify and adjust plans and end points, because the FDA is now desperate for a win themselves....
https://ih.advfn.com/stock-market/USOTC/revive-therapeutics-qb-RVVTF/stock-news/87845219/revive-therapeutics-announces-publication-of-resea
Would be a win for investors if they sold out to bp in my opinion
Safely used for 32 years for RA, repurposed drug for Covid19 and soon for Long Haul Covid19 and other respiratory viruses and Liver transplants. Now in the late stages of an FDA EUA phase Trial, where 710 people were already tested.
No better risk vs reward, over sold, massive upside drug stock in the sector right now, this close to approval... $RVVTF
Massive DD shared and debated here for 2.5 years for new folks to catch up on.... Enjoy
Yes, I was right, again, and they raised 4.3 mil dollars. they raised millions at .10 and .40 and .50 during the 2.5 year Covid19 trial of a safely used for 32 years RA drug, being repurposed for Covid19, that IMO, based on know as of today research, will be proved to be a perfect drug for Long Haul Covid, and not just covid19.
They also have been approved by the FDA to suse the same drug for Liver transplants in an orphan drug trial approval.
That means the FDA like this drug for many applications!!!
Looks to me like a rug pull of RVVTF shorts has panicked RVVTF shorts. Best to cover now before the next news route pushes the stock back to .70/share
It is now clear to me that a Big Pharma operation has hired a hedge fund that shorts stocks and uses short and distort miss information to push stock prices down with fake news claims to scare retail on $RVVTF.
One of the best signs that Big Pharma must be talking to MF and hard bargain pushing him to sell.
That means we need to protect our investment and push the retail backup now.
WE start with all the reasons it is undervalued now. Including
"They just raised 4.3 mil based on 1 share at .15 and I think a warrant at .20 and .72/share
I have been an investor here for years. Big pharma and their FDA are roadblocking RVVTF's Bucci to pressure RVVTF to sell out Bucci.
Followers
|
340
|
Posters
|
|
Posts (Today)
|
0
|
Posts (Total)
|
36602
|
Created
|
02/23/17
|
Type
|
Free
|
Moderators Classic Warrior |
Scientific Rationale of Bucillamine
Preclinical and clinical studies have demonstrated that reactive oxygen species contribute to the destruction and programmed cell death of pulmonary epithelial cells.1 N-acetyl-cysteine (NAC) has been shown to significantly attenuate clinical symptoms in respiratory viral infections in animals and humans, primarily via donation of thiols to restore antioxidant and to reduce the activity of cellular glutathione 2,3,4,5. Bucillamine (N-(mercapto-2-methylpropionyl)-l-cysteine) has a well-known safety profile and is prescribed in the treatment of rheumatoid arthritis in Japan and South Korea for over 30 years. Bucillamine, a cysteine derivative with two thiol groups, has been shown to be 16 times more potent as a thiol donor in vivo than NAC 6. The drug is non-toxic with high cellular permeability. The basis of the clinical study will analyze if Bucillamine has the potential, via restoration of glutathione activity and other anti-inflammatory activity, to lessen the negative consequences of SARS-CoV2 infection in the lungs.
| Psilocin Pharma Corp. has developed production solutions for the active compound Psilocybin. Our process encompassed with our intellectual property cover methods of production of Psilocybin based formulations. Psilocin Pharma Corp’s range of products have been engineered to work synergistically with the body's own natural pathways of absorption while offering a contemporary approach to consumption. Psilocin Pharma also has strong relationships with specific lab partners in certain areas like Brazil, where these formulations are legally approved and plan to sell products in these jurisdictions. | |
| |
Mental Health (Depression, PTSD & Anxiety)
|
Supplements for Brain Health & Cognitive Enhancement
|
Volume | |
Day Range: | |
Bid Price | |
Ask Price | |
Last Trade Time: |