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"At this time, the Company will only provide regular updates via press releases as information becomes available."
This is the first time i've seen this statement in one of Revive's PR. When Biomedical Trader (BMT) sent Revive the letter of questions approximately 5 days ago he stated that he wanted Revive to respond to the questions by the end of business Friday, April 21, 2023.
Because of this latest PR and specifically the "At this time" language in it i have a feeling that Revive (Michael Frank) will forgo providing a non PR response to the letter/questions.
A reminder of the letter...https://www.reddit.com/r/RVVTF/comments/12kpawg/letter_sent_to_the_bod/
Revive Therapeutics Provides Update of Phase 3 Clinical Study for Bucillamine in the Treatment of COVID-19
April 18, 2023 18:44 ET
https://www.globenewswire.com/news-release/2023/04/18/2649628/0/en/Revive-Therapeutics-Provides-Update-of-Phase-3-Clinical-Study-for-Bucillamine-in-the-Treatment-of-COVID-19.html
Revive Therapeutics Provides Update of Phase 3 Clinical Study for Bucillamine in the Treatment of COVID-19
April 18, 2023 18:44 ET
https://www.globenewswire.com/news-release/2023/04/18/2649628/0/en/Revive-Therapeutics-Provides-Update-of-Phase-3-Clinical-Study-for-Bucillamine-in-the-Treatment-of-COVID-19.html
Informal shareholder meeting
https://www.reddit.com/r/RVVTF/comments/12qmj8o/informal_shareholder_meeting/?sort=controversial
Good move CW :)
I remember Fress selling his 1 million RVVTF shares at around 70 cents in December '21 and then disappearing. Smart man! That's not to say we won't ever hit that (and more) again, but how many shares would $700k buy at today's prices?!!!
Lol. You have an excellent memory, Rubber. She does not really understand the concept of owning stocks. She is still holding it and doesn't quite understand what she owns, but I slipped her $100, so that in case of Armageddon, I still remain her favorite uncle
ps. I saw that Merck bought out a company today for, I believe, 11 billion or some crazy number and I peeked, hoping it to be Revive, but until will unblind, nobody knows the extent that Bucillamine works. Yes, there are lots of studies, but big pharm needs clinical studies.
pps. Release the Beast. #Bucy.
CW. How's that niece of yours who you gifted the RVVTF shares to? I hope she knows not to disown her favorite uncle just yet. There could be a twist to this tale.
There seems to be a lot of empirical evidence of this, since Covid19...And the Need for FDA approval of $RVVTF Bucillamine gets more obvious everyday,
This explains much.
https://scitechdaily.com/covid-19-strikes-again-accelerating-dementia-in-the-most-vulnerable/
All subtypes of dementia, irrespective of patients’ previous dementia types, behaved like rapidly progressive dementia following COVID-19, according to the Journal of Alzheimer’s Disease Reports
Infection with SARS-CoV-2 has a significant impact on cognitive function in patients with preexisting dementia, according to new research, published in the Journal of Alzheimer’s Disease Reports. Patients with all subtypes of dementia included in the study experienced rapidly progressive dementia following infection with SARS-CoV-2.
Since the first wave of COVID-19, neurologists have noticed both acute and long-term neurological syndromes and neuropsychiatric sequelae of this infectious disease. Insights into the impact of COVID-19 on human cognition has so far remained unclear, with neurologists referring to “brain fog.” A group of researchers driven to gain a better understanding of and dissipate this fog investigated the effects of COVID-19 on cognitive impairment in 14 patients with preexisting dementia (four with Alzheimer’s disease [AD], five with vascular dementia, three with Parkinson’s disease dementia, and two with the behavioral variant of frontotemporal dementia), who had suffered further cognitive deterioration following COVID-19.
Down with the CEO I have 5 million shares. Let's vote! That lying f* dolt. And his dog eo
Hotel
Keep it simple. Communism by any other name.Vast Majority of the population too ignorant to realize their fate. Im buying an island. F them all! Lol
Take care and God bless america!
Everyone has a need to be correct, but it's important to hear both sides to the story so you can make your own decisions based on your own research. Too many people today try to shut down opposing views which really isn't democracy but socialism or marxism. I like hearing from all of you.
Thanks Gator
I hope all is well
Thanks Gator
I hope all is well
I just wonder sometimes how much the company could do with the Psychedelic side if Bucillamine is finally fda approved, if it works as Bmt think and I trust his expert knowledge of how it should work on covid. If they happen to get 300 m or 1b or a little more...
would be a good time for Bucilllamine to help with this Chit :0
https://twitter.com/MLS_Dave/status/1646911946304675847
#Packers QB Aaron Rodgers will be a featured guest in a psychedelic science conference in June called "Psychedelic Science 2023"
— Dov Kleiman (@NFL_DovKleiman) March 9, 2023
It is dubbed "the largest psychedelic gathering in history.", via @TMZ https://t.co/dwFGfbJLDu pic.twitter.com/TlCNqHng7y
Ear plugs work just as well against the noise of glorified pumpers and those who continuously state that it's "time to load" up.
The only thing I see that sticks out like a sore thumb regarding $RVVTF , is loud, obnoxious, worthless claims to be shareholders that want volume to flip shares.
Ear plugs are sound (LOL) science based devices just like $RVVTF Bucillamine.
Am I the only one that has noticed that some want to pour gasoline on a claimed to be fire ($RVVTF) and claim they are not with the Government and are here to help?
LMAO
The only thing I see that sticks out like a sore thumb regarding $RVVTF , is loud, obnoxious, worthless claims to be shareholders that want volume to flip shares.
Ear plugs are sound (LOL) science based devices just like $RVVTF Bucillamine.
Ditto, on all of that, and it is $RVVTF time to load IMO, well said.
Thanks - i'm all for a review of leadership - just the first I heard about it. Change of leadership or not and while I know the study is already in motion, the focus needs to not be so much about Covid but an overall conversation (MF did imply that he was going to take this route) with the FDA about usage of Buc in general based on it's history.
things that make me go "hhhmmmmm"--
It’s unclear what BMT can do outside of a proxy vote to oust MF. For some reason MF is a hero to sheep and the sheep will stand by him all the way to trips.
Don't know if the reddit group has openly stated some of these things. But my guess is that BMT and possibly the Dr. Icham dude may have some sway on that.
It seems like they are doing their best to cast down a gauntlet. I think it is fair that some of these CEOs have their feet held to the fire when needed. The sense I get is that they feel they are untouchable when it comes to small OTC companies like this.
so do we know who this committee is that is interviewing / doing a search for a new CEO?
You are right. Revive being down has nothing to do with buccillame. The fact revive is down is due to piss poor management.
I don't think Frank will be surprised by the end part you reference CW. If anything it should place him under appropriate and merited pressure per se. If Frank gets emotional about it, it tells us a lot about him plus it would be him clutching at straws as part of a spineless attempt to disregard the letter.
I like and support this initiative put forth by the Reddit consortium. Frank needs to now stand up and be counted as his silence since early March is totally unacceptable and deeply alarming to most (serious) investors.
GL to us all (although luck is not a strategy of course..)
Yep. The letter idea at first made sense however the questions and comments like you just shared open the door for big disappointment
I do sincerely hope im wrong.
I liked the memo until I read the ending again. This will piss off the big guy and hinder getting a solid response.
If all other avenues have been exhausted, it is time to bring on an executive with relevant experience in the pharmaceutical industry to tap into Bucillamine’s potential. We are in discussions with promising candidates and are prepared to offer a recommendation if an experienced candidate for CEO has not been identified by the board.
Thanks for your response Rickstereo. We will see if any of this comes to fruition.
By Mid 2021, the entire market started and has been in a down trend, while $RVVTF rallied and held up until the whole market went totally south 12 moths ago when the US FED started the panic rug pull to kill inflation, "at any cost"
That is my read on a lot of it. Weeks ago there was an 8 million share dump in minutes, with not bid support, by someone. Stock is already up 100% since then
Not even sure it was legal, unless it was shorts and stop losses triggered.
Folks might might want review the history of penny stocks that made the cut in the Past, like Citi Bank, Apple, GM, Ford, Sirius XM (I bought in 2009 for about 2.5 cents/share) all back in 2009... When the markets were all peak doom and gloom...
Any stock that is not profitable, or has debt, and has market revenue risk has gotten hammered, few have prevailed.
One I bought in 2013 around a penny, made it to Nasdaq weeks ago. Opxs...
Meet one of the top famous shorts, talking about penny stocks that made the big time like Apple and SeriusXm, after a near death crash...
https://www.timothysykes.com/blog/most-successful-penny-stocks-in-history/
There are others that could qualify for inclusion but those listed are, imo, the examples that most clearly apply.
As I've consistently insinuated since 2020......methinks "something is rotten in the state of Denmark"....and IMO it's not being done to benefit retail holders!!!!!!!!
1. Management stops defending the stock price.
Been the norm with rvv since it hit 70s and then continued the spiral to single digits with no apparent concern from mike et al.
2. Social media posts are overly bearish and calling for the CEO’s removal.
I could name quite a few but wont lest ""they"" become triggered and require counseling. lololsss
6. “Sell this, buy that.”
See previous answer
7. Bizarre price action prior to upcoming milestones
Again, other than the run to 70s upon news of the trial, literally every major milestone for rvv has seen a minor pop, which was then followed by a reversion to previous and lower levels. Ask yourself this obvious question.......how was it that there was not even the hint of a run based on pure speculation prior to the fda's latest response!?!?!
10. Your stock has become disconnected from reality
From day one the trading here made no sense, especially when viewed with the perspective that there is voluminous scientific data that supports buccy as being an effective, and arguably superior, treatment for covid and its associated indications.
Good stuff. Thank you.
Biomedical Trader (BMT) has stated that the letter (questions) will be sent tomorrow and will post the letter shortly after sending it.
What's the latest on the Reddit group initiative to have CEO Michael Frank respond to a series of shareholder questions? Anyone?
What's the latest on the Reddit group initiative to have CEO Michael Frank respond to a series of shareholder questions? Anyone?
Obtuse Eye. If you look back at my posts I never took a position on the fda. I admitted my ignorance and didn’t object to others including ric who took the position fda was corrupt or bias to BP. I still feel the same way and remain neutral because I admit not knowing enough to form an opinion one way or the other.
What does bother me is this notion of some who say revive has the great drug worth millions and the same folks say the fda will never approve. I’ve been very vocal about that. And why I don’t invest more in this pos.
Hence I’ve said for months if this is the case then it’s MFs responsibility to unlock shareholder value thru some partnership with a BP. I suppose we wait and see. It’s outcome #4 from the last PR. For my part I have doubts about the drug but that’s because of the pps and poor results with FDA process make it unlikely a partnership will emerge. Thankfully I’m only out about 1200 on paper actually a little less since the flip I did a couple weeks back
Of course I hope I’m wrong about the drug and ability to partner.
Great find! I think there are a fair amount here that are not surprised by what is in the article.
It even goes on to point out that the FDA was asked about when they knew of the shortcomings. *SURPRISE*, no answer.
It seems this was a heist from the outset. The kingmakers already knew where the approvals, and the money were going to flow to.
So every company that received EUA for a vaccine have all now been identified in some sort of chicanery in which they either covered of data that would be damning to their materials, or straight lied in order to get their items through. Despite being uncovered, there is NO ONE going to jail, or NO ONE being held accountable.
If anything, any one that so much as calls it out are being discredited, or the information is being glossed over as if it was no big deal.
@govprs, at some point you can acknowledge that there is foul play when it comes to Big PHerm, I mean Big Werm, I mean Big Pharm, and the FDA. ~Sounds like a 70's tv show "B.J. McKay and his best friend Bear".
Totally agree Rick! I found this on twitter. Those of you with more experience than me would know if it is accurate.
https://www.griproom.com/fun/10-signs-your-company-is-about-to-be-acquired?fbclid=IwAR3JTUCwuTKGzupmz1CmHdyi0OyHgcMJB41A0ksrCTLShT2cVnU3PW5U9TI
I've never subscribed to rics pov. Rather I find him as negative as they come
This statement is absolutely mind boggling when one closely examines the source from which it emanated.
IT literally slinks on here to gloat about, and most obviously, gleefully mock those who may have/have experienced monumental losses over the past weeks/months.
#scumbag
Reposted because citing facts that exposed ones weak narrative as being utter bs is inCONvenient.......................
but when there are millions of people testing positive daily and you still can’t enrol 1000 that is on management for not staying on pharm olam.
If only mikey boy had simply screamed at and threatened PharmO daily for only Locating, Testing and then Inviting 700+ persons that fit their stringent qualifying criteria to participate from the overall limited subset of patients, and locations (~47) in ~1.5 yrs (Jan 21-Aug 22), all accomplished while being constrained by limited resource$, they would have surely gotten the additional ~250 persons just to make some alleged SHAREHOLDER that posts gibberish here daily content.
Example of "'logic"" from a muppet.................lololsss
Cool- You're one of my favorite posters. You always find unique and relative items. Now if you can please find a path to recoup some of our loses, the longs will be much obliged.
Pfizer Caught Covering Up Data on Waning Immunity
https://slaynews.com/news/pfizer-caught-covering-up-data-waning-immunity/?utm_source=mailpoet&utm_medium=email&utm_campaign=daily-newsletter
Oh God that is horrible!
I guess that is a nice, easy, simple-minded way to approach this. You can keep on that train of thought.
I think most of us still hold out hope that it will manifest into something tangible. Sadly though, if the President is going to declare the "COVID emergency" officially over, it lessens the urgency at which this will get looked at with real meaning.
So many of us wonder, how truthful was the process all along? It seems pretty clear what side you take on this, your name kinda spells it out. But as Rick has stated, if you choose to look past the practices as we've seen them play out, and then believe that RVV got that same treatment or have not progressed solely because of something they did/didn't do. That is why you're meeting the resistance in opinion.
I never said it was open to everyone but when there are millions of people testing positive daily and you still can’t enrol 1000 that is on management for not staying on pharm olam. It’s not like he can just hire someone and forget about it. He is the ceo. He takes responsibility for everything with the trial. He isn’t getting paid $30k a month to sit around. And why post the starting and estimated completion dates? The completion date has been pushed back 6 times because of how terrible frank has been.
Some FACTS about the trial for the clearly uninformed, ie, a "chocolaty muppet"...................
ClinicalTrials.gov Identifier: NCT04504734
Recruitment Status : Enrolling by invitation
First Posted : August 7, 2020
Last Update Posted : October 27, 2022
Enrolling by invitation: The study is selecting its participants from a population, or group of people, decided on by the researchers in advance.These studies are not open to everyone who meets the eligibility criteria but only to people in that particular population, who are specifically invited to participate.
Actual Study Start Date : November 27, 2020
Estimated Primary Completion Date : December 31, 2022
Estimated Study Completion Date : December 31, 2022
Repeating the same asinine statement ad nauseam about mike intervening only proves how fake the entire premise is, especially when viewed in terms of the hard facts above.......which you never produce.
What a jester! lololsss
@govprs......Wow so many got shammed here. Terrible outcome for heavy bag holders
Ye may have better luck selling this "snake oil" if ye put a little more effort in, instead of making the same inane pitch daily!
Just some food for thought there boyo.....................
Again you keep talking about a changing virus. Yes it changed in early 2022 which still gave the company over a year to get the required patients including in the time of delta which was the worst variant. So you can stop with the changing virus bs. It was up to frank to stay on pharm olam to get the required patients and he didn’t which is why we are here. If you get the required patients in delta this trial is long done and likely we all would have gotten paid.
So this .05 stock will remain a .05 stock because of the fda no matter what??
Wow so many got shammed here. Terrible outcome for heavy bag holders
Yet another response filled with such nonsensical and false drivel that Im aghast that anyone posting here daily with this pseudo ""authority"" could be so uninformed.
Yes let’s keep blaming the fda and using that as an excuse for franks terrible job with this company.
I absolutely do because of numerous examples of CORRUPTION and blatantly selective application of the rules/guidelines, ie, if there was a level playing field, rvv would likely not be in this current predicament. Only those blinded by bias and/or ignorance would claim that the fda doesnt play favorites with a certain "elite" group.
They had more than enough time to enrol the 1000 patients before everything changed.
Yes PharmO had enough time and why they couldnt achieve that goal only they and mike can answer but I suspect it had to do with them noticing the ever changing landscape of the virus, among other factors. However, the fact remains that even if they did complete the 1000 patients, based on fda requirements in 2023, IT WOULD STILL BE REJECTED because the trial did not contain the required data ......this basic fact exposes the utter stupidity of your entire argument.
At this point mike could simply "throw the dice" and go with only the 700+ data and request that the dsmb unblind and decide whether it shows statsig based on the old ep's.....this path was pr'ed months ago by rvv and was based on the ep request being rejected by the fda so maybe the "doom and gloom" crowd should try reading a bit more......remember this!?!....of course ye dont!......................
From an Oct 2022 Pr......................
Should the FDA agree with the revised protocol, the Data Safety Monitoring Board (“DSMB”) will review the completed Post-Dose selection data of approximately 500 subjects in the context of the new primary endpoint. The DSMB may recommend continuing the Study if there is a trend toward achieving statistical significance, halting the Study early due to statistical significance likely not going to be met, or halting the Study early due to positive efficacy showing statistical significance. Regardless of the outcome, the Company would proceed to seek a meeting with the FDA to agree on a proposed plan for potential regulatory approval.
Instead of talking about the fda being corrupt maybe look at how stupid Frank was to go with an endpoint that the fda said not to.
The trial ep's were set in 2020 and agreed to by the fda/dsmb........the fda rejected the pcr standard in 2022 because it was unreliable for assessing ep's in 2022, and they later requested ep data that the original trial, WHICH THEY AGREED TO, did not possess.
Buccy has proven itself to be truly Safe & Effective for over 30 yrs and the fact that SAFETY is the #1 issue re approving a drug, one can only wonder why the fda appears to be delaying the scrutiny of the scrubbed patient data by the DSMB!?!?
Simply allow the evaluation of the 700 data so that it can either be accepted or rejected due to lack of efficacy.......everyone can make up their own minds whether there are ulterior motives at play here or not.
#shills
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Scientific Rationale of Bucillamine
Preclinical and clinical studies have demonstrated that reactive oxygen species contribute to the destruction and programmed cell death of pulmonary epithelial cells.1 N-acetyl-cysteine (NAC) has been shown to significantly attenuate clinical symptoms in respiratory viral infections in animals and humans, primarily via donation of thiols to restore antioxidant and to reduce the activity of cellular glutathione 2,3,4,5. Bucillamine (N-(mercapto-2-methylpropionyl)-l-cysteine) has a well-known safety profile and is prescribed in the treatment of rheumatoid arthritis in Japan and South Korea for over 30 years. Bucillamine, a cysteine derivative with two thiol groups, has been shown to be 16 times more potent as a thiol donor in vivo than NAC 6. The drug is non-toxic with high cellular permeability. The basis of the clinical study will analyze if Bucillamine has the potential, via restoration of glutathione activity and other anti-inflammatory activity, to lessen the negative consequences of SARS-CoV2 infection in the lungs.
| Psilocin Pharma Corp. has developed production solutions for the active compound Psilocybin. Our process encompassed with our intellectual property cover methods of production of Psilocybin based formulations. Psilocin Pharma Corp’s range of products have been engineered to work synergistically with the body's own natural pathways of absorption while offering a contemporary approach to consumption. Psilocin Pharma also has strong relationships with specific lab partners in certain areas like Brazil, where these formulations are legally approved and plan to sell products in these jurisdictions. | |
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