Revelation Biosciences Inc (REVB)

[Klinsmann]

Markets need to turn in general. I still add cheap shares, updates any day gonna bring a multi day runner, at least to the moving averages...

[Arnold25764]

Hoping for it. So far Deep Red days.

[Klinsmann]

A summary:
RS 1-35 followed by the inevitable biotech offering
positive results expected soon, float tiny 3.5 million, a pps equal to 0,06 pre rs...

boooom - imo
Patience gonna pay!

[Klinsmann]

What about some deep green days making you forget the last 2 weeks...?!?

[Arnold25764]

We ever going to see a string of Green days or just sit here Red almost every day?

[Klinsmann]

Nobody here?!? It´s a pity - this gonna be a beautiful reversal for REVB $$

[Klinsmann]

Added even more. This stock gonna generate very nice gains soon. Est. 6-8$...

[Klinsmann]

In! Offering closes today...

[Lonewolf1]

Somebody has been loading here.

[makinezmoney]

$REVBW: Warrants now at 0.0234 .......... hmmmmmmmmmmmmmm


https://static1.squarespace.com/static/5f536d50b94bfb444769fc95/t/63cecb57222ed21134e854cf/1674496860483/Revelation+Biosciences_Corporate_Presentation_Jan2023_FINAL.pdf


GO $REVBW

[frugallife]

OKAY U DA VETERANS. I GAVE U AN EXTRA DAY to add. if not then MONDAY donuts are on u and cookies are on me why. LEVEL UP BITCH.... and find out if u have real money VAMOS!

[frugallife]

time to short this stock because the website is not even real 2020 its 2022. lol

[frugallife]

I see you little girls i will wait and buy more tomorrow this will drop again.

[frugallife]

can yall bring it back down again thanks looking to go the strip club need some ones. Thanks.

[frugallife]

QUICK 500 bucks not a brag but i have beer money this weekend. thank you!

[frugallife]

easy money made when everyone is a sleep. slip in at out in low volume weeks. the OTC is stupid enough to let you do it.

[frugallife]

day two beings 19 great job ladies.

[frugallife]

tomorrow starts day one.

[ttottip]

Can this turn the tables?

[ttottip]

This is going to regain most of today's losses tomorrow.

[ttottip]

Interesting here.

[subslover]

Revelation Biosciences Inc. Announces Positive Results in Preclinical Model of Acute and Chronic Kidney Disease
October 25 2022 - 09:00AM
Business Wire
Alert
Print
Share On Facebook
– Treatment with REVTx-300 significantly reduced renal cortical fibrosis in a dose dependent manner –
– Additional models of fibrotic diseases including AKI, CKD, NASH, and Myocarditis to commence in Q4 2022 –
– Phase 1 clinical study planned for 1H 2023 –

Revelation Biosciences Inc. (NASDAQ: REVB) (the “Company” or “Revelation”), a life sciences company that is focused on the development of immunologic-based therapies for the prevention and treatment of disease, today announced positive results in a preclinical model of acute kidney injury (AKI), chronic kidney disease (CKD). Treatment with REVTx-300 significantly reduced renal cortical fibrosis in a dose dependent manner in the medium and high dose groups (21.7% reduction (p <0.05) and 29.3% (p < 0.05), respectively) and was comparable to a known TGF-ß inhibitor of fibrosis used as a positive control (38.1% reduction (P < 0.05)).

“These promising preclinical results offer hope of new prophylactic option for preventing the deleterious effects of AKI following multiple types of surgery,” said Lakhmir Chawla, M.D. at the Jennifer Moreno Department of Veterans Affairs Medical Center, San Diego, CA, and a leading expert in AKI, “as well as potential new treatment options for active acute kidney injury and chronic kidney disease. I look forward to collaborating with Revelation as REVTx-300 moves through the development process.”

The unilateral ureteral obstruction (UUO) model is appropriate for studying the anti-inflammatory and anti-fibrotic effects of potential new therapies for acute and chronic kidney disease as complete ureteral obstruction of one kidney results in significant inflammation and subsequent fibrosis of the affected kidney over a 7-day period.

The present study consisted of 6 groups with the following outcomes on renal cortical fibrosis as measured by detection of collagen deposition using picosirius red stained histology sections assessed at three different sampling depths.

Group 1 animals had no UUO surgery and received vehicle only (collagen deposition: 2.36 ± 0.44%).
Group 2 animals had UUO surgery and received vehicle only (collagen deposition: 2.36 ± 0.44%).
Group 3 animals had UUO surgery and received SB-525334, a known TGF-ß inhibitor of fibrosis (collagen deposition: 3.02 ± 0.37%, 38.1% reduction vs Group 2, p < 0.05).
Group 4 animals had UUO surgery and received 0.1 mg/kg REVTx-300 (collagen deposition: 4.96 ± 0.95 %, 0% reduction vs Group 2).
Group 5 animals had UUO surgery and received 0.3 mg/kg REVTx-300 (collagen deposition: 3.82 ± 0.91%, 21.7% reduction vs Group 2, p < 0.05).
Group 6 animals had UUO surgery and received 0.9 mg/kg REVTx-300 (collagen deposition: 3.45 ± 0.54%, 29.3% reduction vs Group 2, p < 0.05).
Revelation will continue evaluating the potential of REVTx-300 in additional preclinical models including CKD, nonalcoholic steatohepatitis (NASH), and myocarditis to identify optimal dosing conditions required for prevention and resolution of inflammation and fibrosis. Revelation plans to initiate Phase 1 clinical studies in the first half of 2023.

“This preclinical data along with observations from our previous clinical studies support the validity and promise of our PHAD-based programs to beneficially modulate the inflammatory process,” said James Rolke, Chief Executive Officer of Revelation. “With the increased prevalence of inflammation-mediated diseases, we remain focused on leveraging PHAD-specific stimulation of TLR4 to discover therapies to provide relief from conditions including AKI, CKD, myocarditis, and NASH.”

About REVTx-300

REVTx-300 is our proprietary formulation for systemic administration of PHAD and is being developed as a potential therapy for the treatment of acute and chronic organ disease including chronic kidney disease (CKD, acute kidney injury (AKI), myocarditis, and nonalcoholic steatohepatitis (NASH). Chronic disease of an organ, due to chronic inflammation and subsequent fibrosis, follows a pattern of perpetual and ongoing destruction of living functional cells and subsequent replacement by the non-functional protein, collagen, resulting in fibrosis (scar tissue) (Wilson). The establishment of fibrosis and subsequent death of the organ is driven by ongoing inflammatory processes and reactive oxygen species associated with the innate immune response. We believe redirection of the innate immune response with REVTx-300 from a pro-inflammatory state to an anti-inflammatory (protective) state may rebalance the innate immune response to slow down or halt the progressive destruction and scarring of organ tissue, allowing the healing process to take place.

About Revelation Biosciences Inc.

Revelation Biosciences, Inc. is a life sciences company focused on the development of immunologic-based therapies for the prevention and treatment of disease. Revelation has multiple product candidates in development that are based on the well-established biology of phosphorylated hexaacyl disaccharide (PHAD) and its effect on the innate immune system. REVTx-100 is being developed as a prevention and treatment of infection. REVTx-200 is being developed as an intranasal immunomodulator adjunct to be used in combination with an intramuscular vaccination for more complete immunity. REVTx-300 is being developed as a potential therapy for the treatment of acute and chronic organ disease including CKD, AKI, myocarditis, and NASH. REVTx-99b is being developed as a treatment for food allergies. REVDx-501 is being develope

[kzivann]

Looks like this may have a couple up days.


REVB

[kzivann]

Nice news. Nice move.

REVB

[subslover]

REVB. up up and away!

[subslover]

REVB. up up and away!

[kzivann]

Drifted down. Bid filled.

REVB

[kzivann]

Premarket volume. PPS up. News. Will pop PPS continue.

REVB

[MASTERULTRA]

$.53c baby!!!

[MASTERULTRA]

When I see the bid is $.5175 and ask is $.535 thats a whide spread someone is signal or something has been leaked.

[MASTERULTRA]

If shorts dont cover I feel sorry for them. Usually when company completes an offering there's always good news coming afterwards Company gives an update.

[MASTERULTRA]

2 weeks ago they completed an offering. So, something big is coming.

[MASTERULTRA]

Someome recueved an Email from the company saying NEWS coming this friday? Can someone confirm this?

[Cubanwinner]

We may see a run to dollar land soon

[willlbone]

Dilution slap.

[subslover]

Revelation Biosciences Surges After Encouraging Data From Allergic Rhinitis Study
https://www.benzinga.com/general/biotech/22/07/28183340/revelation-biosciences-surges-after-encouraging-data-from-allergic-rhinitis-study

[investingnotgambling]

Thought 75 cents was a deal today. Sheesh. Gotta love Fridays.

[MASTERULTRA]

3 White Soldiers = Bullish tomorrow jmo.

Your VTEC is outdated. REVB about to run to $5 dollars is my PRICE TARGET. goodluck to you!!!

[hondaboost]

Alert: REVB, might go bankruptcy soon!

[duderaja]

Looks like the pull back might be starting already. Don't be greedy and not take profit when you can. There appears to be no reason for this spike in price.

[duderaja]

Never a mistake to take some profit. You can never pick the top or bottom and if you try usually end up holding the bag.

[trendzone]

With out a doubt it's really high risky to buy it up here, I also bought the warrants yesterday at five cents and sold them at $0.11, wish I would have kept my sell order at $0.14, would have got filled there like half a minute later after I sold them.

[Invest-in-America]

REVBW: Grabbed their WARRANTS big time at the Open!!

[duderaja]

Had I heard of this stock when it was .5 I might have bought in, but you can't see everything. If it retraces and I expect it will, I may get in.

[trendzone]

They have been having some positive data updates recently, on its hay fever treatment intranasal REVTx-99b,perhaps some upcoming positive data was leaked to certain institutions that decided they wanted in no mater what, and apparently yesterday's after hours action ment something,when traders were able to buy at $0.65 to $0.87, today's premarket high $1.60 to $1.90, I have been in since early April and average down on it five times, with buys below $0.50, also added more after hours at $0.75,so for me the after hours action meant something, and it paid off.

[subslover]

Hi, how are you? Correct, if you're not inside then your outside. Amazing volume too!

[duderaja]

Thanks for the response. I'm always suspicious when a stock spikes for no reason and since I never heard of REVB before today I'll pass for now but will be watching to see what happens.

[subslover]

Revelation Biosciences (NASDAQ: REVB) stock is up 130% premarket this morning on no really obvious news releases. This follows a 27% price rise in REVB stock yesterday. This is, of course, nice for those stockholders who were in the SPAC process, who have lost 93% of their money since the combination back in January. The question is, well, what's driving this stock price rise? There is no obvious news release to explain it, so we'll have to make some surmises.

Revelation is a clinical-stage biopharmaceutical company focussing on immune system therapeutics and diagnostics. So, there's significant effort and business opportunity in covid, influenza, rhinosinusitis and so on. So far so good, although there doesn't seem to have been any grand announcement about anything from the FDA to explain suh a stock price rise.

[duderaja]

After hours usually means squat. Is anything going on with REVB to cause this spike besides what some are seeing in the chart?

[trendzone]

$REV up 27% today,and now up another 36% after hours,something must be up, and possibly leaked out,for all of this big strong buying today,and especially after hours.