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RXI Pharmaceuticals Corp (RXII)

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Last Post: 9/20/2018 10:18:46 AM - Followers: 134 - Board type: Free - Posts Today: 0

About RXi Pharmaceuticals

RXi Pharmaceuticals Corporation (OTC: RXII) is a biotechnology company focused on discovering, developing and commercializing innovative therapies based on its proprietary, next-generation RNAi platform.  Therapeutics that use RNA interference, or "RNAi," have great promise because of their ability to "silence," or down-regulate, the expression of a specific gene that may be overexpressed in a disease condition.  Building on the pioneering work of scientific founder and Nobel Laureate Dr. Craig Mello, RXi's first RNAi product candidate, RXI-109, entered into RXi's first human clinical trial in 2012.  RXI-109 targets connective tissue growth factor (CTGF), a key regulatory of fibrosis and scar formation, and is initially being developed to reduce or inhibit scar formation in the skin following surgery.


RXi Pharmaceuticals Corp., has received patent approval for their new experimental breast cancer vaccine which became part of the company's arsenal after acquiring Apthera Inc. in April of this year.
The specific patents in question regard using the vaccine NeuVax with the drug Herceptin which is used in women to slow the production of the HER2 protein in tumors, while NeuVax attempts to make the body's immune system fight off cancerous cells.
According to The Telegram:
"The patents also cover using NeuVax in patients not eligible for Herceptin treatment."
With their patent in place the company plans to begin human tests in early 2012.
According to RXi the patents were developed by Dr. George E. Peoples, director of the Cancer Vaccine Development Program for the U.S. Military Cancer Institute and RXi is leasing the patents for their own work.


This May, RXi Pharmaceuticals Corp. observed two momentous events: The biotechnology company completed its spinoff from Galena Biopharma Inc., and Dr. Geert Cauwenbergh took the helm as president and chief executive officer. The small company's first product, an anti-scarring medication called RXI-109, entered clinical trials this year, and is based on the pioneering work in RNA interference of RXi scientific founder and Nobel Laureate Dr. Craig C. Mello. Dr. Cauwenbergh came to RXi after a long career in pharmaceuticals, most recently as president and chief executive officer of a company he founded, Barrier Therapeutics. What attracted you to come to Worcester? "It was the technology, well, the technology and the chemistry with these people. They're very bright." As a publicly traded company, how do you reconcile the needs of the investors, which are sometimes a short-term desire for profits, with the needs of medical research, which sometimes takes years? "Through business development. Basically what you do as a small biotech is you try to create a big network with people who have interest in various stages of development. ... In two or three years they get antsy and they want to cash in, but at that point in time there will be and there is already a network of business development contacts in place where you can for instance get nondiluted money without having to raise money and go back to the stock market and shareholders by making regional deals or geographic deals ...


June 9, 2015 RXi Pharmaceuticals Strengthens Intellectual Property Portfolio for Novel RNAi Platform

Dec 17, 2014 RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301

Press Releases
RXi Pharmaceuticals to Present at Biotech Showcase™ 2013 - December 19, 2012
RXi Pharmaceuticals Announces Initiation of Second Double-Blind Vehicle Controlled Phase 1 Study With Its Anti-Scarring Compound, RXI-109 - December 5, 2012
RXi Pharmaceuticals Announces Pharmacokinetic Results of its Single Dose Phase 1 Study with RXI-109 in Healthy Volunteers - November 15, 2012
RXi Pharmaceuticals Reports Financial Results for the Third Quarter of 2012 - November 14, 2012
RXi Pharmaceuticals to Present at 12th Annual Biotech Symposium - October 16, 2012
RXi Pharmaceuticals Awarded NCI SBIR Funding to Advance Self-Delivering RNAi Technology - October 4, 2012
RXi Pharmaceuticals to Present at 11th Annual BIO Investor Forum - October 2, 2012
RXi Pharmaceuticals Announces Completion of Dosing in Phase 1 Trial for RXI-109 Program - September 24, 2012
RXi Pharmaceuticals Reports Financial Results for the Second Quarter of 2012 - August 15, 2012
RXi Pharmaceuticals Appoints Jeannette Graf MD and Leroy Young MD to its Scientific Advisory Board - July 13, 2012
Share Statistics
Avg Vol (3 month)3: 215,443
Avg Vol (10 day)3: 145,371
Shares Outstanding5: 338m
Float: 53.34M
% Held by Insiders1: 9.01%
% Held by Institutions1: 0.50%

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PlusOneCoin Top Posts
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#4688   Well, here we go. Thanks Geert for another The Other Guy 09/20/18 10:18:46 AM
#4687   A few pennies here, a few there. The Other Guy 09/18/18 04:46:34 PM
#4686   How soon will we be sub-$1 again? The Other Guy 09/17/18 10:03:46 AM
#4685   well if i spelled correctly it would have NGIN 09/15/18 06:44:14 PM
#4684   Use spellcheck when you hashtag please. The Other Guy 09/15/18 12:41:25 PM
#4683   Geert Just screwed over us sh once again. #SUCMBAG NGIN 09/14/18 07:16:55 PM
#4682   On our way to RS#3. Geert being The Other Guy 09/14/18 04:06:04 PM
#4681   I don’t believe RXI is a scam. But The Other Guy 09/14/18 02:39:30 PM
#4680   BOD of RXII are as crooked as everyone NGIN 09/14/18 02:36:29 PM
#4679   I thought this BOD had more credibility. It The Other Guy 09/14/18 02:16:05 PM
#4678   Its great to Se the Dr. Frost has NGIN 09/14/18 02:12:16 PM
#4677   EVERY DEAL is lousy for sh and we NGIN 09/14/18 02:07:31 PM
#4676   Geert will now slow play any partnership in The Other Guy 09/14/18 09:40:37 AM
#4675   What a deal as a CEO; tank the The Other Guy 09/04/18 11:27:21 AM
#4674   Market is unimpressed with Geert’s empty promises. The Other Guy 08/15/18 10:03:36 AM
#4673   Geert had better halt his own pay so The Other Guy 08/14/18 10:04:42 PM
#4672   What is the likelihood? Well, if we The Other Guy 08/14/18 10:00:21 PM
#4671   At least Geert bought shares of the company. The Other Guy 08/14/18 09:55:48 PM
#4670   RXI's business model (dilute ad nauseum until you sabaidii2 08/14/18 08:53:55 PM
#4669   Geert initially makes it sound as though a The Other Guy 08/14/18 07:16:19 PM
#4668   “ "In comparison with our track record for The Other Guy 08/14/18 09:58:40 AM
#4667   Pressure continues to be on Geert. I hope The Other Guy 08/14/18 09:23:53 AM
#4666   * * $RXII Video Chart 08-01-18 * * ClayTrader 08/01/18 05:20:57 PM
#4665   Got 1,95/96 europtiger 08/01/18 09:47:42 AM
#4664   Stock started downward again on the opening. I stargazer123 07/11/18 01:44:25 PM
#4663   The stock price leveled out the last few stargazer123 07/10/18 11:41:28 PM
#4662   Why ruin a good thing? The Other Guy 07/10/18 04:52:18 PM
#4661   * * $RXII Video Chart 07-10-18 * * ClayTrader 07/10/18 04:50:23 PM
#4660   "I am more interested" sabaidii2 06/07/18 03:50:51 PM
#4659   sabaidii2, You make a good straight man. terry hallinan 06/07/18 03:13:23 PM
#4658   "What think you of that, Sabaidii2?" You make sabaidii2 06/07/18 02:38:37 PM
#4657   sabaidii2, barring a deal, expect dilutions on a regular terry hallinan 06/05/18 02:08:06 PM
#4656   Nice news, nice float.. could get interesting here. UP Trend 05/18/18 12:12:42 PM
#4655   "The float is a concern to me, I sabaidii2 05/16/18 08:34:13 PM
#4654   Thanks for taking the time to put that joe_techi 05/16/18 08:12:28 PM
#4653   "Thinking about a starter position" sabaidii2 05/16/18 06:05:09 PM
#4652   Thinking about a starter position joe_techi 05/16/18 05:07:52 PM
#4651   It was a good cc yesterday. Today’s collaboration The Other Guy 05/11/18 11:48:57 AM
#4647 / Report Suspected Securities Fraud or Wrongdoing NGIN 04/30/18 01:21:48 PM
#4646   RXII Been oversold FOR 4+ YEARS....that's a totally NGIN 04/30/18 01:19:40 PM
#4645   "How oversold can we get?" sabaidii2 04/28/18 06:06:52 PM
#4644   Oversold so much that it dropped another 15c. The Other Guy 04/28/18 02:27:36 PM
#4643   RXII 2.80 OVERSOLD last IPO 3.15, I am Blutribe 04/20/18 09:51:38 AM
#4642   How many people fell for the halt to The Other Guy 04/04/18 08:23:19 PM
#4641   * * $RXII Video Chart 04-04-18 * * ClayTrader 04/04/18 05:24:02 PM
#4640   nice SM! $RXII +30% with multiple presentations coming $treet $inatra 04/04/18 10:29:14 AM
#4639 [SMART MONEY] 04/04/18 10:02:12 AM
#4638   weeeeeeeeeeeeee crowin 04/04/18 09:59:59 AM
#4637   yep I hope people read this stuff and Inoviorulez 03/28/18 06:07:30 PM
#4636   I AGREE 1000% And would avoid RXII at NGIN 03/28/18 09:21:58 AM