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What goes up hard comes down hard , looks like no profits, in 5 to 10 years maybe .
This stock has been on fire!!!!!
XON on CNBC today, up 15%+ in 2 days, looks like a beast of a LT play.
It has been in this price channel for a few months now. A traded familiar with their pattern would have done really well.
BAC-ML healthcare conference Tuesday May 12th.
RJ Kirk will be presenting at 8:40am pst.
Food is a small part of the overall picture.
Takes years to grow those apple trees before any profit is seen plus PE is very high .
How patience pays in biotechnology
http://www.biohealthinvestor.com/
Look at these prices of these leaders in Big cap bio just between 2 to 4 years ago. If you could afford to buy just say 500 to 1k shares you would be close to a millionaire. The only thing more important than having the funds to have bought them was to have the patience to hold through all the bumps in the road.
Are the previous holders of MEDS which acquired XON through buyout satisfied with their agreement?
Abstracts on Sleeping Beauty Released
http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=e8b9bf9f-ac96-4582-a814-8a4feb688c9a&cKey=e1449847-2960-4d43-8a62-864f0b16cf73&mKey=19573a54-ae8f-4e00-9c23-bd6d62268424
http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=2dc87f5d-bfb3-4e4d-8f48-e2567464386a&cKey=f586761e-ab49-4c79-b4b3-84b36b5bb555&mKey=19573a54-ae8f-4e00-9c23-bd6d62268424
30% of XON has been shorted ,shorts will hire and bash bash bash till they can get in low , it is a sad state when a short can sells shares and cover in 10 days .
XON to meet with JPM in May
http://www.theflyonthewall.com/permalinks/entry.php/XONid2015845/XON-Intrexon-management-to-meet-with-JPMorgan
Updated Griffin report - post earnings
Food and Healthcare Likely to Carry 2015
Several collaborators will advance human therapeutics into
clinical trials this year. Overall, Intrexon figures that about 10
products developed with its assistance will be in testing. Ziopharm
alone will likely account for at least half of them and two other
companies, Fibrocell Science and Synthetic Biologics, will have
one each. Another therapy that was mentioned was developed as
part of the Sun Pharma joint venture in ophthalmology. Recently
acquired ActoGenix has two clinical-stage programs involving
genetically modified bacteria for oral mucositis and inflammatory
bowel disease, which will probably be partnered soon.
A pending acquisition will expand Intrexon’s presence in
the food sector… The Company has agreed to pay $41 million
for Okanagan Specialty Fruits, including $10 million in cash and
the remainder in XON stock. The deal, which should close by
June, will bring two approved, non-browning apple varieties into
the product line and add three similar genetically modified fruit
programs to the R&D pipeline. Note that we do not expect
revenues from Okanagan until 2017.
…while Trans Ova should drive revenues this year. This
subsidiary, which was acquired last August, will likely generate
close to $100 million in revenue from its dairy and cattle
embryo sales and in vitro fertilization services. Demand, which
is seasonally strongest in the June quarter, is growing at a rapid
pace.
Intrexon closed 2014 on a pleasant note. Fourth-quarter
revenues benefited from $15.1 million in sales and service
revenues from Trans Ova in its first full quarter with the
Company. The other major contributor was $13 million in
collaboration revenues. Operating expenses were generally in
line with expectations. The profit margin on product and service
revenues, which were generated largely by Trans Ova, amounted
to 29% during the seasonally weak December interim. R&D costs
increased 41%, to $59 million, while selling and administrative
expenses jumped 61%, to $64 million, due largely to acquisitions.
Overall, the operating loss increased modestly from year-toyear,
to $19 million. More than offsetting that was unrealized
appreciation in stocks of the Company’s collaborators, which
resulted in a $0.19-a-share profit in the quarter.
We are maintaining our BUY recommendation on Intrexon
shares and our $65 price target.
http://www.griffinsecurities.com/viewpdf.php?docid=959
Tom,
CorMedix, Inc. (CRMD) -NYSE MKT
6.16 Up 0.66(12.00%) 4:02PM EST
After Hours : 6.19 Up 0.03 (0.49%) 7:03PM EST
Yes Ziop down.......profit taking?
ZIOPHARM Oncology, Inc. (ZIOP) -NasdaqCM
13.34 Up 0.85(6.81%) 4:00PM EST
After Hours : 12.94 Down 0.40 (3.00%) 7:48PM EST
Tell me how both CRMD and ZIOP are walked down red after hours?
I went from being up 20k+ to being down 1300 for the day.
I hope CRMD opens at 5.40 tomorrow like the last trade for 1K.
I know ya can't reply here. Look for your thoughts on IV
Let it consolidate for a minute. Needs to churn in 40's so it doesn't have a heavy bleed.
For every flipper grabbing quick profits stronger hands are buying. Is up almost 100% in a month.
What about ADXS and MDGN?
The 3 Amigo's are rolling along
XON ZIOP CRMD
CRMD news out this am, looks good.
I wasn't obv serious, but this will be over a $50.00 stock tomorrow and this news hasn't even been seen by some of the big plays...we could see $55.00 easy by EOW.
Should be fun tomorrow
Apples
Not so fast Apples... i am sure we will see some profit taking at the end of the run which would be a good entry point, i agree this could be a 100.00 stock at some point but not in a month, XON has some great potential in many different area's.
POSITIVE RESULTS FOR CANCER STOCK, THIS COULD SEE $100.00 IN A MONTH, LOW O/S
This is huge, Shorts are gonna cover soon...that alone will push this to $55.00 maybe sooner then I originally though...if your not in yet, this is a must own stock at 48.00
are they covering today??? up 6.35 KABOOM I just opened a position yesterday morning, ZIOP & CRMD are my 2 biggest holdings. i am paitently waiting for CRMD to get taken out so i can flip the funds right into XON
which will be a long term hold for me. I hate when that happenes!!!!
At what price does anyone think the shorts will finally cover ??
They must be in a world of hurt just about now....
...I wonder how much higher a short squeeze would push up the price??
XON running I'm in at 33.09
Looking for 53.09
Should be early next week
Apples
Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results
http://finance.yahoo.com/news/intrexon-announces-fourth-quarter-full-210500595.html
"Looking ahead, we are very excited about our near term prospects and have much higher goals for 2015. In Health, we expect to see new major alliances formed, while we believe that our existing ECC partners will be in the clinic with up to ten novel therapeutic candidates. In Food, we anticipate continued growth of our base business with projected product and service revenues exceeding $100M," said CEO Randal Kirk of the company's prospects in 2015.
your welcome. check it out especially if you trade real biotech stocks. plenty of solid LT investors sharing critical DD. I find it really helpful along with doing my own DD.
Investors Villiage.
Investors community with boards on certain stocks like here. Lots of info on both XON and ZIOP posted. Much more than here.
May I ask what is "IV"?
Yeah, cowbunga, Bill Miller yikes! That's awesome. Bill Miller is an excellent trader. Did you see in the interview how they talked about Miller's timing of Amazon and why he went all in after the 3rd quarter earnings conference? Absolutely awesome market timing and he did it because of how the word "productivity" was used twice. The CNBC article referred to Intrexon as being the health care stock of the decade! Whoa. Source: This could be the stock of the decade: Bill Miller
The only thing I don't like about Intrexon is that the EPS forecast is going down even though the revenue is rocketing upward. But that's definitely something that is fixable and can be turned around.
XON received a Bill Miller recommendation on CNBC AH this afternoon.
That accounts for price jump AH, it appears. Love these buy analysts who come on media and kind of front-run what they have already invested in. But I have not checked to see whether Miller's fund is invested in XON already. Anyone care to guess?
Sorry, I misspelled it. Meant to say stocktwits, link below
http://stocktwits.com/symbol/XON?q=Xon
No familiar with stockwits.
I read that board as well & follow RobCos recommendations. I'm also on stocktwits-m22
If you are invested in XON or ZIOP then I beleive IV is the place to be.
Not that I am recommending you do your DD through a message board but its a bigger community for both of these tickers there. IMO
If you are invested in XON or ZIOP then I beleive IV is the place to be.
Not that I am recommending you do your DD through a message board but its a bigger community for both of these tickers there. IMO
Exclusive Licensing Agreement for CAR T Cell, TCR, NK Cell Programs and Associated Technologies for the Development of Non-Viral Adoptive Cellular Therapies
Combined Technologies to Leapfrog Clinical Pipeline of Next Generation Therapies Using Synthetic and Personalized Immunology
GERMANTOWN, Md., BOSTON, and HOUSTON, Jan. 13, 2015 /PRNewswire/ -- Intrexon Corporation (NYSE: XON), a leader in synthetic biology and its oncology partner, ZIOPHARM Oncology (NASDAQ: ZIOP), today announced a broad exclusive licensing agreement with The University of Texas MD Anderson Cancer Center, including an exclusive sublicensing agreement through MD Anderson for intellectual property developed at the University of Minnesota for the development of non-viral adoptive cellular cancer immunotherapies.
The licensed technologies arise from the laboratory of Laurence Cooper, M.D., Ph.D., professor of pediatrics at MD Anderson and Perry Hackett, Ph.D., professor within the College of Biological Sciences at Minnesota.  The Cooper and Hackett laboratories have pioneered the design and clinical investigation of novel chimeric antigen receptor (CAR) T cell therapies using non-viral gene integration platforms. MD Anderson has built on this technology to deliver patient-derived T cells, as well as innovative approaches to generating products for universal off-the-shelf applications.  When combined with Intrexon's technology suite and ZIOPHARM's clinically tested RheoSwitch Therapeutic System® interleukin-12 modules, the resulting proprietary methods and technologies may help realize the promise of genetically modified CAR T cells by tightly controlling cell expansion and activation in the body, minimizing off-target effects and toxicity while maximizing therapeutic efficacy.
"Genetically engineering our patients' immune-system T cells to efficiently attack and destroy cancer cells represents one of the most exciting approaches with curative potential in oncology today," MD Anderson President Ron DePinho, M.D., said. "We believe coupling MD Anderson's unique CAR T cell approach with the powerful technologies of ZIOPHARM and Intrexon will allow us to build T cells that hit cancer harder, with greater precision, under tighter control and with potentially fewer side effects for patients. This agreement ranks as one of MD Anderson's most substantial collaborations and will provide significant resources to fuel its mission of Making Cancer History®."
"We are proud to see Perry Hackett's discovery and development work on Sleeping Beauty, a non-viral DNA plasmid-based gene transfer system, in conjunction with Dr. Cooper's expertise in immunotherapies, provide this breakthrough in oncology" said Brian Hermann, Vice President of Research at the University of Minnesota.
Employing novel cell engineering techniques and multigenic gene programs, the collaboration will implement next-generation non-viral adoptive cellular therapies based on designer cytokines and CARs under control of RheoSwitch® technology targeting both hematologic and solid tumor malignancies. The synergy between the platforms will be leveraged to accelerate a promising synthetic immunology pipeline, with up to five CARs expected to enter the clinic in 2015 and off-the-shelf programs initiating in 2016.
"It is a shared vision to maximize the speed and breadth of multigenic innovation for patients through the use of nimble, non-viral DNA cell manufacturing strategies that can further overcome viral packaging constraints and economic limitations," stated Gregory Frost, Ph.D., Senior Vice President and Head of Intrexon's Health Sector. Â "Collectively, this will assemble the most advanced set of technologies to empower the strongest adoptive cell therapy pipeline that can drive innovation through multiple horizons and patient populations."
Cooper, Hackett and colleagues developed a non-viral DNA plasmid-based gene transfer system to modify T cells by creating a CAR that recognizes and binds to a specific cell surface protein on targeted malignant cells. The testing of this system at MD Anderson in humans paves the way for the rapid design and implementation of modified T cells that can be infused into patients with many types of malignancies.
Work continues in conjunction with MD Anderson's Moon Shots Program, an ambitious initiative to accelerate the conversion of scientific discoveries into clinical advances and significantly reduce cancer deaths, first targeting eight types of cancer. Cooper leads the Applied Cellular Therapeutics platform for the moon shots, providing expertise and new cellular therapy capabilities for both blood and solid tumor cancers. Clinical trials using non-viral adoptive cellular therapies are either under way or planned for specific moon shot cancers.
The shared infrastructure between MD Anderson, Intrexon and ZIOPHARM enables two approaches to deliver these commercially viable T cells to the bedside.  The first develops a point-of-care approach with rapid assembly and infusion of autologous T cells.  The second arises from the universal donor platform to infuse off-the-shelf T cells using innovative activation and targeting gene programs that precisely recognize and systemically combat malignancies. The collaboration will advance these platforms in parallel with the most effective CAR-T products tested at MD Anderson graduating to multicenter trials.
"The promise of controlled, cell-based immuno-oncology therapy is that we can achieve dramatic, long duration anti-cancer results while keeping patients out of intensive care during treatment. As importantly, we can reproduce these results in a globally scalable and economically viable way," remarked Jonathan Lewis, M.D., Ph.D., Chief Executive Officer of ZIOPHARM Oncology. "The MD Anderson Cancer Center has long been a leader in cancer therapy, in terms of innovation, patient care, and the highest quality research. As part of our commitment to this important partnership and the acceleration of translational medicine, ZIOPHARM will build a base of operations in Houston to join and collaborate with the academic and medical community around this world-class institution."
"The human application of T cell therapies provides cancer patients with new hope, and the alignment of MD Anderson's immunotherapy and translational programs with Intrexon and ZIOPHARM will help make that hope a reality," Cooper said. "These two interconnected companies have first-in-class genetic tools and systems to reprogram cells and the management and regulatory expertise to undertake development of potent and focused cell-based immunotherapies."
Under the terms of the agreement, MD Anderson shall receive consideration of $100 million; $50 million from each Intrexon and ZIOPHARM, payable in shares of their respective common stock, as well as a commitment of $15 to $20 million annually over three years for researching and developing the technologies.  The parties will enter into additional collaboration and technology transfer agreements to accelerate technology and clinical development. Further details on the terms of the transaction will be available within the current reports on Form 8-K filed today by Intrexon and ZIOPHARM.
About Intrexon Corporation
Intrexon Corporation (NYSE: XON) is a leader in synthetic biology focused on collaborating with companies in Health, Food, Energy, Environment, and Consumer Sectors to create biologically-based products that improve the quality of life and the health of the planet. Through the company's proprietary UltraVector® platform and suite of technologies, Intrexon provides its partners with industrial-scale design and development of complex biological systems. The UltraVector® platform delivers unprecedented control over the quality, function, and performance of living cells. We call our synthetic biology approach and integrated technologies Better DNA®, and we invite you to discover more at www.dna.com.
About ZIOPHARM Oncology, Inc.
ZIOPHARM Oncology is a Boston, Massachusetts-based biotechnology company employing novel gene expression and control technology to deliver DNA for the treatment of cancer. ZIOPHARM's technology platform employs Intrexon Corporation's RheoSwitch Therapeutic System^® technology to turn on and off, and precisely modulate, gene expression at the cancer site in order to improve the therapeutic index. This technology is currently being evaluated in Phase 2 clinical studies of the immune system cytokine interleukin-12 for the treatment of breast cancer and advanced melanoma. The Company's synthetic immuno-oncology programs in collaboration with Intrexon also include chimeric antigen receptor T cell (CAR-T) approaches.
About MD Anderson
The University of Texas MD Anderson Cancer Center in Houston ranks as one of the world's most respected centers focused on cancer patient care, research, education and prevention. It is one of only 41 comprehensive cancer centers designated by the National Cancer Institute (NCI). For the past 25 years, MD Anderson has ranked as one of the nation's top two cancer centers in U.S. News & World Report's annual "Best Hospitals" survey. It receives a cancer center support grant from the NCI of the National Institutes of Health (P30 CA016672).
Trademarks
Intrexon, UltraVector, RheoSwitch Therapeutic System, RheoSwitch, RTS, and Better DNA are trademarks of Intrexon and/or its affiliates. Other names may be trademarks of their respective owners.
Forward-Looking Safe Harbor Statement:
This press release contains certain forward-looking information about ZIOPHARM Oncology, Inc. and Intrexon Corporation that is intended to be covered by the safe harbor for "forward-looking statements" provided by the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements are statements that are not historical facts. Words such as "expect(s)," "feel(s)," "believe(s)," "will," "may," "anticipate(s)" and similar expressions are intended to identify forward-looking statements. These statements include, but are not limited to, statements regarding our ability to successfully develop and commercialize our therapeutic products; our ability to expand our long-term business opportunities; our future presentations at industry meetings; financial projections and estimates and their underlying assumptions; and future performance. All of such statements include certain risks and uncertainties, many of which are difficult to predict and generally beyond the control of the company, that could cause actual results to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. These risks and uncertainties include, but are not limited to: whether   any of our other therapeutic discovery and development efforts will advance further in  pre-clinical research or in the clinical trials process and whether and when, if at all, they will receive final approval from the U.S. Food and Drug Administration or equivalent foreign regulatory agencies and for which indications; whether any other therapeutic products we develop will be successfully marketed if approved; our ability to achieve the results contemplated by our collaboration agreements; the strength and enforceability of our intellectual property rights; competition from other pharmaceutical and biotechnology companies; the development of, and our ability to take advantage of, the market for our therapeutic products; our ability to raise additional capital to fund our operations on terms acceptable to us; general economic conditions; and the other risk factors contained in our periodic and interim SEC reports filed from time to time with the Securities and Exchange Commission, including but not limited to, our Annual Reports on Form 10-K for the fiscal year ended December 31, 2013 and our Quarterly Reports on Form 10-Q for the quarter ended September 30, 2014. Readers are cautioned not to place undue reliance on these forward-looking statements that speak only as of the date hereof, and we do not undertake any obligation to revise and disseminate forward-looking statements to reflect events or circumstances after the date hereof, or to reflect the occurrence of or non-occurrence of any events.
whoops last post off topic wrong forum... anyway i think squawk on the strreet was very wary of xon$... im out
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