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Phio Pharmaceuticals Corp (PHIO)

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Last Post: 3/31/2020 8:00:14 PM - Followers: 134 - Board type: Free - Posts Today: 0

About RXi Pharmaceuticals

RXi Pharmaceuticals Corporation (OTC: RXII) is a biotechnology company focused on discovering, developing and commercializing innovative therapies based on its proprietary, next-generation RNAi platform.  Therapeutics that use RNA interference, or "RNAi," have great promise because of their ability to "silence," or down-regulate, the expression of a specific gene that may be overexpressed in a disease condition.  Building on the pioneering work of scientific founder and Nobel Laureate Dr. Craig Mello, RXi's first RNAi product candidate, RXI-109, entered into RXi's first human clinical trial in 2012.  RXI-109 targets connective tissue growth factor (CTGF), a key regulatory of fibrosis and scar formation, and is initially being developed to reduce or inhibit scar formation in the skin following surgery.


RXi Pharmaceuticals Corp., has received patent approval for their new experimental breast cancer vaccine which became part of the company's arsenal after acquiring Apthera Inc. in April of this year.
The specific patents in question regard using the vaccine NeuVax with the drug Herceptin which is used in women to slow the production of the HER2 protein in tumors, while NeuVax attempts to make the body's immune system fight off cancerous cells.
According to The Telegram:
"The patents also cover using NeuVax in patients not eligible for Herceptin treatment."
With their patent in place the company plans to begin human tests in early 2012.
According to RXi the patents were developed by Dr. George E. Peoples, director of the Cancer Vaccine Development Program for the U.S. Military Cancer Institute and RXi is leasing the patents for their own work.


This May, RXi Pharmaceuticals Corp. observed two momentous events: The biotechnology company completed its spinoff from Galena Biopharma Inc., and Dr. Geert Cauwenbergh took the helm as president and chief executive officer. The small company's first product, an anti-scarring medication called RXI-109, entered clinical trials this year, and is based on the pioneering work in RNA interference of RXi scientific founder and Nobel Laureate Dr. Craig C. Mello. Dr. Cauwenbergh came to RXi after a long career in pharmaceuticals, most recently as president and chief executive officer of a company he founded, Barrier Therapeutics. What attracted you to come to Worcester? "It was the technology, well, the technology and the chemistry with these people. They're very bright." As a publicly traded company, how do you reconcile the needs of the investors, which are sometimes a short-term desire for profits, with the needs of medical research, which sometimes takes years? "Through business development. Basically what you do as a small biotech is you try to create a big network with people who have interest in various stages of development. ... In two or three years they get antsy and they want to cash in, but at that point in time there will be and there is already a network of business development contacts in place where you can for instance get nondiluted money without having to raise money and go back to the stock market and shareholders by making regional deals or geographic deals ...


June 9, 2015 RXi Pharmaceuticals Strengthens Intellectual Property Portfolio for Novel RNAi Platform


Dec 17, 2014 RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301


Press Releases
RXi Pharmaceuticals to Present at Biotech Showcase™ 2013 - December 19, 2012
RXi Pharmaceuticals Announces Initiation of Second Double-Blind Vehicle Controlled Phase 1 Study With Its Anti-Scarring Compound, RXI-109 - December 5, 2012
RXi Pharmaceuticals Announces Pharmacokinetic Results of its Single Dose Phase 1 Study with RXI-109 in Healthy Volunteers - November 15, 2012
RXi Pharmaceuticals Reports Financial Results for the Third Quarter of 2012 - November 14, 2012
RXi Pharmaceuticals to Present at 12th Annual Biotech Symposium - October 16, 2012
RXi Pharmaceuticals Awarded NCI SBIR Funding to Advance Self-Delivering RNAi Technology - October 4, 2012
RXi Pharmaceuticals to Present at 11th Annual BIO Investor Forum - October 2, 2012
RXi Pharmaceuticals Announces Completion of Dosing in Phase 1 Trial for RXI-109 Program - September 24, 2012
RXi Pharmaceuticals Reports Financial Results for the Second Quarter of 2012 - August 15, 2012
RXi Pharmaceuticals Appoints Jeannette Graf MD and Leroy Young MD to its Scientific Advisory Board - July 13, 2012
Share Statistics
Avg Vol (3 month)3: 215,443
Avg Vol (10 day)3: 145,371
Shares Outstanding5: 338m
Float: 53.34M
% Held by Insiders1: 9.01%
% Held by Institutions1: 0.50%


Current Price
Bid Ask Day's Range
  • 1D
  • 1M
  • 2M
  • 3M
  • 6M
  • 1Y
  • 2Y
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  • 5Y
PHIO News: Statement of Ownership (sc 13g) 02/14/2020 02:52:49 PM
PHIO News: Current Report Filing (8-k) 02/13/2020 05:27:09 PM
PHIO News: Statement of Ownership (sc 13g) 02/13/2020 05:25:17 PM
PHIO News: Prospectus Filed Pursuant to Rule 424(b)(4) (424b4) 02/12/2020 05:22:26 PM
PHIO News: Notice of Effectiveness (effect) 02/12/2020 06:01:05 AM
#4874   COULD BE AN OTC STOCK SOON edwardport 03/31/20 08:00:14 PM
#4873   This BIO SCAM sure did imo Thats ALL NGIN 03/31/20 01:31:19 PM
#4872   Company screwed investors today. Release positive news and The Other Guy 03/31/20 01:19:43 PM
#4871   Could really get going over 3.70 or so. eebbee 03/31/20 07:54:16 AM
#4870   PR Newswire March 31, 2020, 6:30 am Animal studies show Beano1969 03/31/20 07:47:20 AM
#4869   CV play ?? shurtha2000 03/11/20 11:00:15 AM
#4868   Read yesterday’s news... Liquid1974 03/11/20 07:27:14 AM
#4867   Why is this stock moving today? Noseyrosey 03/11/20 07:25:33 AM
#4866   Looking for entry Liquid1974 03/11/20 07:12:18 AM
#4865   PHIO is a TOTAL bio PONZI SCAM imo...what NGIN 02/11/20 09:46:57 AM
#4864   6c pre-RS. What a hack job being The Other Guy 02/11/20 09:43:28 AM
#4863   The only news PHIO releases is about reverse The Other Guy 02/08/20 12:40:12 PM
#4862   Also, it is because of Nasdaq that these reverse The Other Guy 01/15/20 04:31:56 PM
#4861   Sadly, a 55/1 reverse split brings such a The Other Guy 01/15/20 04:13:43 PM
#4860   And I had gone through a couple of stargazer123 01/15/20 03:18:15 PM
#4859   THE BIGGEST bio SCAM the past 20 yrs. NGIN 01/15/20 11:05:00 AM
#4858   Yes, that was a sad disappointment. No press stargazer123 01/15/20 12:17:15 AM
#4857   * * $PHIO Video Chart 01-14-2020 * * ClayTrader 01/14/20 05:57:57 PM
#4856   1-55 R/S news out today proffetti 01/14/20 01:09:33 PM
#4855   Good job......BUT now---> "The Company is taking steps 420man 01/12/20 09:23:19 AM
#4854   I am 470% up since last week ... CyrusDaVirus 01/10/20 08:36:59 PM
#4853   Lol yes- i am on the sidelines - CyrusDaVirus 01/10/20 08:33:52 PM
#4852   Another pump pre RS...this is like ground hog 420man 01/10/20 07:52:18 PM
#4851   Dip and rip CyrusDaVirus 01/10/20 09:56:10 AM
#4850   Closed at .2535 + 38.2% (Not 12.8%) stargazer123 01/09/20 11:39:36 PM
#4849   Reverse split may be canceled stargazer123 01/09/20 09:57:58 PM
#4848   * * $PHIO Video Chart 01-09-2020 * * ClayTrader 01/09/20 04:32:35 PM
#4847   target is 30 today Aevora 01/09/20 11:24:51 AM
#4846   Hod break coming europtiger 01/09/20 11:12:51 AM
#4845   Great volume europtiger 01/09/20 10:24:38 AM
#4844   PHIO going europtiger 01/09/20 10:20:32 AM
#4843   What’s the catalyst to make this pop? ron007 01/08/20 03:59:31 PM
#4842   * * $PHIO Video Chart 01-02-2020 * * ClayTrader 01/02/20 04:16:59 PM
#4841   Good morning Phio SCAM FAM! #bioSCAM still in NGIN 12/30/19 09:52:53 AM
#4840   It’s a matter of time, I’m sure it’s FROZENFLAME 12/06/19 11:13:31 AM
#4839   With very little volume... but I am sure europtiger 12/06/19 11:03:58 AM
#4838   Very very tight trading !!!! FROZENFLAME 12/06/19 10:14:07 AM
#4837   Dip and split :D my new phrase im stock1ace1 12/04/19 10:51:12 AM
#4836   I sold again... europtiger 12/04/19 10:31:56 AM
#4835   Yeah 0,18 Break be great europtiger 12/04/19 09:59:25 AM
#4834   It should after yesterday volume, lots of shares FROZENFLAME 12/04/19 09:58:59 AM
#4833   Hope so... need so,e volume here europtiger 12/04/19 09:56:26 AM
#4832   Dip and rip $$$$ FROZENFLAME 12/04/19 09:48:40 AM
#4831   Would be great to see a little eod europtiger 12/03/19 02:27:06 PM
#4830   Very strong that big ask is done in FROZENFLAME 12/03/19 01:09:20 PM
#4829   Some flippers on the way they should be FROZENFLAME 12/03/19 01:01:04 PM
#4828   L2 super thin should have a nice pop . FROZENFLAME 12/03/19 12:56:31 PM
#4827   I did buy it... let’s stay up there europtiger 12/03/19 12:55:45 PM
#4826   17s up let’s GO $$$$$ FROZENFLAME 12/03/19 12:55:34 PM
#4825   17s coming soon $$$ FROZENFLAME 12/03/19 12:54:23 PM