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Phio Pharmaceuticals Corp (PHIO)

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Last Post: 3/19/2019 2:28:32 PM - Followers: 135 - Board type: Free - Posts Today: 0

About RXi Pharmaceuticals

RXi Pharmaceuticals Corporation (OTC: RXII) is a biotechnology company focused on discovering, developing and commercializing innovative therapies based on its proprietary, next-generation RNAi platform.  Therapeutics that use RNA interference, or "RNAi," have great promise because of their ability to "silence," or down-regulate, the expression of a specific gene that may be overexpressed in a disease condition.  Building on the pioneering work of scientific founder and Nobel Laureate Dr. Craig Mello, RXi's first RNAi product candidate, RXI-109, entered into RXi's first human clinical trial in 2012.  RXI-109 targets connective tissue growth factor (CTGF), a key regulatory of fibrosis and scar formation, and is initially being developed to reduce or inhibit scar formation in the skin following surgery.


RXi Pharmaceuticals Corp., has received patent approval for their new experimental breast cancer vaccine which became part of the company's arsenal after acquiring Apthera Inc. in April of this year.
The specific patents in question regard using the vaccine NeuVax with the drug Herceptin which is used in women to slow the production of the HER2 protein in tumors, while NeuVax attempts to make the body's immune system fight off cancerous cells.
According to The Telegram:
"The patents also cover using NeuVax in patients not eligible for Herceptin treatment."
With their patent in place the company plans to begin human tests in early 2012.
According to RXi the patents were developed by Dr. George E. Peoples, director of the Cancer Vaccine Development Program for the U.S. Military Cancer Institute and RXi is leasing the patents for their own work.


This May, RXi Pharmaceuticals Corp. observed two momentous events: The biotechnology company completed its spinoff from Galena Biopharma Inc., and Dr. Geert Cauwenbergh took the helm as president and chief executive officer. The small company's first product, an anti-scarring medication called RXI-109, entered clinical trials this year, and is based on the pioneering work in RNA interference of RXi scientific founder and Nobel Laureate Dr. Craig C. Mello. Dr. Cauwenbergh came to RXi after a long career in pharmaceuticals, most recently as president and chief executive officer of a company he founded, Barrier Therapeutics. What attracted you to come to Worcester? "It was the technology, well, the technology and the chemistry with these people. They're very bright." As a publicly traded company, how do you reconcile the needs of the investors, which are sometimes a short-term desire for profits, with the needs of medical research, which sometimes takes years? "Through business development. Basically what you do as a small biotech is you try to create a big network with people who have interest in various stages of development. ... In two or three years they get antsy and they want to cash in, but at that point in time there will be and there is already a network of business development contacts in place where you can for instance get nondiluted money without having to raise money and go back to the stock market and shareholders by making regional deals or geographic deals ...


June 9, 2015 RXi Pharmaceuticals Strengthens Intellectual Property Portfolio for Novel RNAi Platform


Dec 17, 2014 RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301


Press Releases
RXi Pharmaceuticals to Present at Biotech Showcase™ 2013 - December 19, 2012
RXi Pharmaceuticals Announces Initiation of Second Double-Blind Vehicle Controlled Phase 1 Study With Its Anti-Scarring Compound, RXI-109 - December 5, 2012
RXi Pharmaceuticals Announces Pharmacokinetic Results of its Single Dose Phase 1 Study with RXI-109 in Healthy Volunteers - November 15, 2012
RXi Pharmaceuticals Reports Financial Results for the Third Quarter of 2012 - November 14, 2012
RXi Pharmaceuticals to Present at 12th Annual Biotech Symposium - October 16, 2012
RXi Pharmaceuticals Awarded NCI SBIR Funding to Advance Self-Delivering RNAi Technology - October 4, 2012
RXi Pharmaceuticals to Present at 11th Annual BIO Investor Forum - October 2, 2012
RXi Pharmaceuticals Announces Completion of Dosing in Phase 1 Trial for RXI-109 Program - September 24, 2012
RXi Pharmaceuticals Reports Financial Results for the Second Quarter of 2012 - August 15, 2012
RXi Pharmaceuticals Appoints Jeannette Graf MD and Leroy Young MD to its Scientific Advisory Board - July 13, 2012
Share Statistics
Avg Vol (3 month)3: 215,443
Avg Vol (10 day)3: 145,371
Shares Outstanding5: 338m
Float: 53.34M
% Held by Insiders1: 9.01%
% Held by Institutions1: 0.50%


Current Price
Bid Ask Day's Range
  • 1D
  • 1M
  • 2M
  • 3M
  • 6M
  • 1Y
  • 2Y
  • 3Y
  • 5Y
PHIO News: Statement of Changes in Beneficial Ownership (4) 03/01/2019 09:25:46 AM
PHIO News: Statement of Changes in Beneficial Ownership (4) 02/19/2019 08:55:21 AM
PHIO News: Current Report Filing (8-k) 02/15/2019 05:01:42 PM
PHIO News: Phio Pharmaceuticals Appoints Gerrit Dispersyn as New Chief Executive Officer Effective March 1 02/15/2019 07:15:00 AM
PHIO News: Amended Statement of Ownership (sc 13g/a) 02/14/2019 02:21:21 PM
PlusOneCoin Top Posts
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#4735   The company has until May 13th to regain The Other Guy 03/19/19 02:28:32 PM
#4734   When do they need to obtain $1 price d-train 03/19/19 12:12:53 PM
#4733   Not to be a wet blanket but this The Other Guy 03/18/19 09:25:18 PM
#4732   It's been climbing for almost two weeks, and stargazer123 03/18/19 08:11:49 PM
#4731   I like how this is up after hours TechnoAnalyst 03/18/19 07:58:49 PM
#4730   run, run ....run Wallstreetwarriors 03/13/19 10:31:05 AM
#4729   "RXI/PHIO reeks of failure. Absolutely no one is stargazer123 03/12/19 02:39:52 PM
#4728   $$$ A potential run is coming here, I Wallstreetwarriors 03/11/19 05:35:41 PM
#4727   "I believe there is value" sabaidii2 01/07/19 06:44:07 PM
#4726   If you believe there is zero chance of The Other Guy 01/02/19 04:26:06 PM
#4725   "Geert will drag out a deal for the sabaidii2 12/23/18 06:03:34 PM
#4724   The board has agreed to allow Geert to The Other Guy 12/21/18 09:19:21 AM
#4723   $PHIO ~ Starting to show good signs of THREE-DAY-TRADER 12/06/18 03:57:41 PM
#4719   RIP RXII The Other Guy 12/03/18 03:09:37 PM
#4718   * * $RXII Video Chart 11-12-18 * * ClayTrader 11/12/18 04:08:04 PM
#4717   $RXII - On the short sale circuit breaker Backstabbed 11/12/18 09:36:54 AM
#4716   $RXII - After being heavily shorted, it is Backstabbed 11/10/18 03:22:26 PM
#4715   $RXII - Afternoon rally after shorts cover this am? Backstabbed 11/09/18 11:56:57 AM
#4714   Why waste your time here? There are The Other Guy 11/09/18 09:56:44 AM
#4713   * * $RXII Video Chart 11-08-18 * * ClayTrader 11/08/18 05:32:43 PM
#4712   7 million shares traded before midday. Up only The Other Guy 11/08/18 11:53:15 AM
#4711   RXi Pharmaceuticals to Present New Data Demonstrating the The Other Guy 11/07/18 09:57:55 AM
#4710   More of the SAME lying BS from this NGIN 11/07/18 08:51:51 AM
#4709   RXi Pharmaceuticals to Webcast Third Quarter 2018 Financial The Other Guy 11/06/18 10:58:23 AM
#4708   Another pay period coming to a close this The Other Guy 10/22/18 03:49:43 PM
#4707   Geert continues to slow play any deal while The Other Guy 10/19/18 01:24:25 PM
#4706   there's already been 3 R/Ss lol..whats another 2 NGIN 10/16/18 01:52:04 PM
#4705   Reverse split #3 is in progress. Thank The Other Guy 10/11/18 03:53:52 PM
#4704   Running out of nickels Geert. At least The Other Guy 10/11/18 03:51:09 PM
#4703   50cents Geert. What are you going to The Other Guy 10/10/18 11:08:48 AM
#4702   TOTAL SCUMBAG Geert is! MAJOR Bio Con-artist IMO too. NGIN 10/01/18 09:26:51 PM
#4701   What a scumbag Geert is! The first The Other Guy 10/01/18 03:45:34 PM
#4700   Nope scary larry 10/01/18 10:28:57 AM
#4699   BOUNCE? DD 10/01/18 10:09:03 AM
#4698   Will someone at RXi please put fiduciary duty The Other Guy 10/01/18 09:55:44 AM
#4697   RXII down 28% because Geert thinks that funding The Other Guy 09/28/18 04:09:41 PM
#4696   So much for any positive gain from the The Other Guy 09/28/18 02:43:34 PM
#4695   Interesting how the poster PR was released. The Other Guy 09/28/18 12:54:55 PM
#4694   Geert’s attempt to bring non-dilutive financing appears to The Other Guy 09/28/18 11:33:51 AM
#4693   I fo confirm with u ;) europtiger 09/27/18 12:49:42 PM
#4692   Did collect average 1,68 Im this could see another europtiger 09/27/18 12:48:52 PM
#4691   No, it’s being pumped so shares can be The Other Guy 09/27/18 11:30:25 AM
#4690   Well chart was very bullish and low floater investor86 09/27/18 10:15:34 AM
#4689   Another fake runup to sell shares into the The Other Guy 09/27/18 09:51:09 AM
#4688   Well, here we go. Thanks Geert for another The Other Guy 09/20/18 10:18:46 AM
#4687   A few pennies here, a few there. The Other Guy 09/18/18 04:46:34 PM
#4686   How soon will we be sub-$1 again? The Other Guy 09/17/18 10:03:46 AM
#4685   well if i spelled correctly it would have NGIN 09/15/18 06:44:14 PM
#4684   Use spellcheck when you hashtag please. The Other Guy 09/15/18 12:41:25 PM
#4683   Geert Just screwed over us sh once again. #SUCMBAG NGIN 09/14/18 07:16:55 PM