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IT IS TOO OLD TO GET IT to 'Schrogtergracht' on 'Neoleukin Therapeutics Inc (NLTX)'
Does anybody here regularly speak to somebody of the company?
Could you ask them to review (and possibly edit) the homepage of their website? "industry leaders", true or not, is just preposterous. One would expect lifestyle-scientists next (Being a scientist primarly to support a lifestyle). No offence intended of course.
Thank you in advance.
We have big plans for NLTX. But that could be a while. So i'd rather see a #PFE or other Big Pharma step in and take over. We'll manage the possible miss. Priorities, priorities. Floor that virus!
Just imagine, every escape covered by a protein 'from the shelf'.
https://www.eurekalert.org/pub_releases/2021-01/aaft-adt011121.php
That, ofcourse, for as long as AI and Quantum computing still aren't plug-and-play (see earlier message on that. The end goal)
That's fine with me, mick. I was irritated by your pennystock link, so I thought I would join you in that. Usually works. Please, don't forget to delete the pennystock link-message, yours.
Neoleukin Therapeuti (NLTX)
12.89 ? -1.02 (-7.33%)
Volume: 271,250 @01/13/21 7:56:09 PM EST
Bid Ask Day's Range
12.0 12.95 12.84 - 13.85
NLTX Detailed Quote
Wonderful. That's why the range? Merry Christmas everybody.
Neo-2/15 is very small and very stable. Because we designed it from scratch, we understand all its parts, and we can continue to improve it making it even more stable and active,” Silva Manzano added.
https://www.oncozine.com/neoleukin-2-15-neo-2-15-a-novel-immunotherapy-agent-designed-to-avoiding-common-side-effects/
The "from scratch"... Through 'less is more' to an optimal design.
Employ A.I., quantum computing and the moment you can map and describe the one it automatically produces the other.
Instant medicines; unique and infinite
Piece of cake. Now where's the monies?
The medical equivalent of bitcoin.
Compute the appropriate proteine form/structure, compute the hash.
Earn your dose, earn your coin.
Thank you for playing.
Where's that Chinese/Saudi funded Japanese creep with his tentacles in Silicon Valley? The 'creator' of the 100 leaders of the future?... The singularity. Not without ITER ready, the minimum. That's 2025. Last week the Chinese produced the first miniscule blackholes.
And this morning I read about the Galaxy probably being littered with civilisations that went extinct ages ago. It seems intelligent life is destined to selfdestruct according to some doctrine.
All's well...
Why would Gates let this go?
Why would he want to put distance between himself and the NLTX product?
What made the guys leave?
If it ain't ethics, it's politics.
Don't let it get away.
Is this trading in a dark pool? The quote 11.48 is outof range according to the real-time Cboe max so far being 11.42. ?
Highly recommendable / please share:
https://en.wikipedia.org/wiki/Rosetta@home
For research purposes surely, but maybe you'd like to do more and help?
It is not selling that drives the share price down.
Either the shareprice is close to a target below and moving into striking distance or there is news on the way.
The spike protein itself is changing...
https://www.reuters.com/article/health-coronavirus-britain-variant/new-coronavirus-strain-spreading-in-uk-has-key-mutations-scientists-say-idUSKBN28P158
One does what one can (be it late, very late):
https://www.theguardian.com/world/2020/dec/20/we-need-even-tougher-curbs-to-fight-this-new-coronavirus-strain
Ah, in DJT the D stands for Delusional?
https://www.nzherald.co.nz/world/covid-19-coronavirus-trump-slams-uks-tightening-of-restrictions/6MQXFJMMPV6OJOYF7Q5LVBYIFA/
There is no cure (so far). Lockdowns are merely an attempt to get a grip on the situation still on course of totally spinning outof control.
https://eand.co/super-covid-is-here-and-you-should-be-very-worried-32a6a549449
Time somebody buys out NLTX; to sort out their priorities and possibly free them from any .orange-projects. Time is of an essence here.
A 'Pfizer' can buy an infinite pipeline in one go. Do they see it?
Or should the hedgies drive up the price first?
'Paging Mrs Nourial Tambour, paging Mrs Nourial Tambour'
In the meanwhile:
create classes of materials and medicines that haven’t been synthesized before.
Synthetic polymers are things like plastics, polyester and nylon. Biological polymers are collections of molecules.
looking at biological polymers, such as DNA, to generate synthetic materials able to replicate biological functions. “Ribosomes, a cell structure that makes protein, can incorporate new kinds of monomers (scientific term for molecules which bind to form polymer material) which can be bonded with identical molecules to form polymers
The ability to harness and adapt cellular machinery to produce non-biological polymers would, in essence, bring synthetic materials into the realm of biological functions
engineering synthetic materials which merge with or mirror actions of living biological organisms ~...Uhoh~
re-engineering biological machinery to allow it to work with non-biological building blocks that would offer a route to creating synthetic polymers with the precision of biology
hmmm...
The Gates-pipedream hijacked by the pentagon? The pentagon wouldn't go freeloading and tap the stockmarket, would it? And maybe go stealth on the pacifist brains that just want to help people?
That calls for a double concerto to contemplate:
Possibly more news/analysis:
https://www.marketscreener.com/quote/stock/NEOLEUKIN-THERAPEUTICS-I-65218886/?type_recherche=rapide&mots=nltx
https://www.stck.pro/news/NLTX/9754971
https://stocktwits.com/symbol/NLTX
https://www.tipranks.com/stocks/nltx/stock-analysis
Here she really takes the biscuit (for trying to saw her violin in two, Beautiful!)
Buy low, sell high. So what is low? From all targets I've seen by analysts etc. the consensus one year out seems to indicate 80% upside.
https://stocktwits.com/symbol/NLTX
https://www.tipranks.com/stocks/nltx/stock-analysis
Maybe shareholders are being conditioned with this range so they'll be 'very impressed' with the premium offered?
Looks like it. 'Stop the steal!'
P.S.
The encore of the Nobelprize 2018 Concert with Lisa Batiashvili, who is already Sonderklasse. (As for NLTX... tiktok
'Ambition'. It's a fickle thing.
Saw somebody from UW commenting somewhat like: 'yes, that's how we figured, designed and made it. Now we will see wat will come of it'.
Entirely different story/attitude at NLTX, right? Right?
Look at the lady play. One of the most challenging pieces for violin (Brahms) that exist. Concert in Munich under Gergiev. She is putting the bar up there and goes pushing the envelope. Not holding back. You've seen nothing so beautiful before, even if you don't particulary like the music or the lady.
Let it be an inspiration. Because at NLTX you have something you need to put right up there. Push the envelope, don't let them run you over.
Wonderful how you see the members of the orchestra one by one coming around and wondering what is going on and then give their best to be best and part of it.
Watch the lady play. It'll help you, help you work and solve stuff.
Never seen so many nasal sprays under development...
People are going to need more nostrils. Any stem cell scientists in da house?
There ís somebody out there...
Hi Phosphene, there is an article in Wired today but it is in Japanese. Some keywords in English though, so I know it is about NLTX, computerdesigned molecules and the Rosetta software. It appears they have a theme week: 'THE WORLD IN 2021' and the article dated today: december 15, 2020
https://wired.jp/membership/2020/12/15/designer-protein-covid-19-2/
Can you get it translated? Me clumsy. Don't feel obliged. Thank you.
Meanwhile... on the one hand the computer designed medicine, on the other the superior but algo-elusive medicine:
Neoleukin Therapeutics Announces Submission of Investigational New Drug Application for NL-201 De Novo Protein Immunotherapy Candidate for Cancer
https://newsfilter.io/a/b8afd83998b987547841548028dd6548
Must read:
https://www.bnnbloomberg.ca/first-covid-vaccines-triumph-raises-hope-for-cancer-fight-1.1535883
About how mRNA got boosted by Covid-19 and now can take on a role in the fight against cancer and HIV f.i..
It has become an industry almost overnight. And Big Pharma is moving and on a 'forced' spending-spree.
Note the need for design and (individual) applications.
Keyrole here for NLTX, in my opinion. Hope they are out there now, 'making hay'.
P.S. Note the Big players, their projects and alliances. It's a snapshot, category: 'on the brink' (of the revolution
Molecular medicine, genes identified.
Researchers at Edinburgh University identified five genes commonly featured in the DNA of Covid-19 victims.
TYK2, CCR2, OAS1, IFNAR2, and DPP9.
TYK2 is found on chromosome 19 in the human body and creates and enzyme that can lead to inflammation. The scientists believed TYK2 can be treated using baricitinib – a JAK inhibitor used to treat rheumatoid arthritis.
CCR2 is found on chromosome 4 with the researchers identifying drugs already used to treat psoriasis as being effective in treating the gene.
OAS1 is found on chromosome 12 and is already known to be susceptible to other types of coronavirus – while treatment is not yet available.
IFNAR2 is found on chromosome 21 and is key to helping the body’s natural antiviral response identify that there is a virus that needs to be attacked. The researchers found that the IFNAR2 gene can lead to the body’s immune system attacking itself if not treated early.
DPP9 is also found on chromosome 19 - however, the researchers do not yet know enough about the gene to understand what would be the best treatment for it but suspect the gene could lead to ‘long Covid’ symptoms.
'Antibodies Good. Machine-Made Molecules Better?'
November 21, 2020
Article; Interview NLTX and explanation
https://elmoudjaweb.com/antibodies-good-machine-made-molecules-better-jaweb/
Highly recommendable article; insightful, explanations and views by the researchers/employees of Neoleukin themselves, well-written.
See also post #45
The vaccines aren't the answer. At best those keep whole swats of people away from medical care so the latter doesn't collapse already. Think of the vaccines in the light of crowd control.
Sadly, it'll be medicine that'll have to save the day(s). And the whole pandemic appears to come down to a matter of an auto-immune disease.
In short, if so, symptoms will be many and very diverse and medicine will have to be tailored to the individual/small groups of individuals.
At this very moment there is nothing better suited to that task than what these guys here at NLTX are working at.
If I see it... tik,tok
P.S. First I thought Kiadis had the best platform, but Sanofi thought so too. And who am I to refuse a 240%+ premium?
Then Pharming caught my eye. Promising, for sure. And they'll be listing on the Nasdaq very soon.
Looking around, checking out pharma I stumble on these guys...
Please sell. Somebody is accumulating. Ofcourse the more of you go, the higher and sooner my premium.
Dear Santa,
Make some multi-billion pharma giant buy out this company.
Whatever project NLTX have running now and whatever project is in the drawers, all need to be multiplied by a factor 10 and put on parallel tracks on a slight tangent.
We, the People, need this WARPSPEED'd, like NOW.
Thank you.
Nasal spray... that's billion$
October 23, 2020; Science Vol. 370, Issue 6515, pp. 426-431
Note espec. end of article "Acknowledgments, Author contribution"
https://science.sciencemag.org/content/370/6515/426 (research article)
[UW, David Baker, Neoleukin, nasal spray, Moderna?]
September 9, 2020
"used computer design to originate new proteins that bind tightly to SARS-CoV-2 Spike protein and obstruct it from infecting cells. Beginning in January, more than two million candidate Spike-binding proteins were designed on the computer. Over 118,000 were then produced and tested in the lab."
https://newsroom.uw.edu/news/designed-antiviral-proteins-inhibit-sars-cov-2-lab (explanatory)
[UW, David Baker]
January 9, 2019
https://www.sciencemag.org/news/2019/01/researchers-redesign-cancer-busting-protein-without-side-effects
Abstract:
"UW has licensed Neo-2/15 to a Seattle startup-Neoleukin Therapeutics to bring it to clinical trials"
https://www.genscript.com/antibody-drug-development-news/hope-for-cancer-patients-an-immune-boosting-protein-without-side-effects-created.html (explanatory)
[UW, Rosetta, Neoleukin]
Pfhizer should put up/own up.
What's with their mini stealth holding here? Only marking their turf? They must be awash with cash by now. Stop playing around. Jumpstart these guys. Push them through their programs. Donate some hardware or steal all of it right now (you know you will anyway)
It's all great stuff/good research. And the People need it, like yesterday.
Help them help you to help us.
P.S. Slow-science is so pre-2020!
Neoleukin Therapeuti (NLTX)
12.55 ? 0.65 (5.46%)
Volume: 96,392 @12/07/20 3:05:22 PM EST
Bid Ask Day's Range
12.44 12.55 11.81 - 12.69
NLTX Detailed Quote
Neoleukin Therapeuti (NLTX)
11.9 ? -0.1 (-0.83%)
Volume: 150,016 @12/04/20 4:00:11 PM EST
Bid Ask Day's Range
11.8 13.75 11.76 - 12.195
NLTX Detailed Quote
Neoleukin Therapeutics Announces Third Quarter 2020 Financial Results and Corporate Update
https://www.globenewswire.com/news-release/2020/11/09/2122736/0/en/Neoleukin-Therapeutics-Announces-Third-Quarter-2020-Financial-Results-and-Corporate-Update.html
Neoleukin Therapeutics Announces Publication in Science of De Novo Protein Decoys that Block COVID-19 Infection In Vitro and Protect Animals In Vivo
https://www.globenewswire.com/news-release/2020/11/05/2121395/0/en/Neoleukin-Therapeutics-Announces-Publication-in-Science-of-De-Novo-Protein-Decoys-that-Block-COVID-19-Infection-In-Vitro-and-Protect-Animals-In-Vivo.html
Neoleukin Therapeuti (NLTX)
11.44 ? 0.3 (2.69%)
Volume: 292,125 @10/23/20 4:03:22 PM EDT
Bid Ask Day's Range
9.65 15.5 10.75 - 11.555
NLTX Detailed Quote
Neoleukin Therapeutics Appoints Holly K. Vance as General Counsel
Ms. Vance joins Neoleukin from the Bill & Melinda Gates Foundation, where she served as Associate General Counsel and provided legal and strategic guidance on investments and transactions to the foundation’s Strategic Investment Fund with a focus in the life sciences sector.
https://finance.yahoo.com/news/neoleukin-therapeutics-appoints-holly-k-120000309.html
Neoleukin Therapeutics Announces Abstract Accepted for Presentation at the Society for Immunotherapy of Cancer’s 35th Anniversary Annual Meeting (SITC 2020)
https://www.globenewswire.com/news-release/2020/10/14/2108775/0/en/Neoleukin-Therapeutics-Announces-Abstract-Accepted-for-Presentation-at-the-Society-for-Immunotherapy-of-Cancer-s-35th-Anniversary-Annual-Meeting-SITC-2020.html
Neoleukin Therapeuti (NLTX)
12.51 ? 0.16 (1.30%)
Volume: 178,102 @09/04/20 4:00:13 PM EDT
Bid Ask Day's Range
10.5 12.5 11.755 - 12.8024
NLTX Detailed Quote
Neoleukin Therapeuti (NLTX)
12.29 ? 0.32 (2.67%)
Volume: 224,316 @08/14/20 5:22:45 PM EDT
Bid Ask Day's Range
9.47 13.38 11.52 - 12.3
NLTX Detailed Quote
Neoleukin Therapeuti (NLTX)
10.56 ? -0.48 (-4.35%)
Volume: 277,776 @07/24/20 4:43:16 PM EDT
Bid Ask Day's Range
10.2 12.12 10.48 - 10.9
NLTX Detailed Quote
Neoleukin Therapeuti (NLTX)
14.0 ? -3.01 (-17.70%)
Volume: 2,630,684 @07/02/20 7:46:20 PM EDT
Bid Ask Day's Range
14.0 19.3 14.0 - 14.9099
NLTX Detailed Quote
Neoleukin Therapeuti (NLTX)
16.24 ? 1.1 (7.27%)
Volume: 487,637 @06/30/20 3:35:24 PM EDT
Bid Ask Day's Range
16.24 16.3 14.61 - 16.36
NLTX Detailed Quote
Neoleukin Therapeuti (NLTX)
15.38 ? -1.64 (-9.64%)
Volume: 4,677,724 @06/26/20 7:54:52 PM EDT
Bid Ask Day's Range
14.88 16.2 14.8001 - 17.34
NLTX Detailed Quote
Neoleukin Therapeuti (NLTX)
12.2 ? 0.01 (0.08%)
Volume: 215,035 @06/05/20 4:00:00 PM EDT
Bid Ask Day's Range
11.35 12.7 11.87 - 12.68
NLTX Detailed Quote
Neoleukin Therapeuti (NLTX)
12.14 ? -0.02 (-0.16%)
Volume: 199,974 @05/27/20 4:00:00 PM EDT
Bid Ask Day's Range
9.47 12.6 11.16 - 12.34
NLTX Detailed Quote
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360-1616 Eastlake Avenue East
Seattle, WA 98102
https://www.neoleukin.com/Neoleukin Therapeutics is seeking an exceptional Principal Scientist to lead its efforts in the field of Mammalian Protein expression. The selected candidate will participate in research programs targeting the expression, characterization, and optimization of de novo designed protein therapeutics. The scope of the research will include (but is not limited to) production of complex recombinant proteins and biochemical, biophysical, and thermodynamic characterization. Examples of targets are cytokines, cell-signaling molecules, and soluble forms of membrane cytokine receptors.
The candidate must have at least five years of industry experience in expression, purification, characterization and optimization of recombinant proteins in mammalian systems, including the expression of human antibodies, cytokines, and cytokine receptors.
The appointed scientist will be responsible for designing and managing research programs in collaboration with senior management, as well as to translate our high-level strategic vision into a scientific reality. As an early-stage biotech company, Neoleukin thrives on developing an inspiring work environment that foremost embraces a collaborative team-based approach.
Neoleukin Therapeutics is proud to be an equal opportunity employer.
All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin,
veteran or disability status, or age, and Neoleukin will not tolerate discrimination or harassment based on any of the above characteristics.
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