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Mosaic ImmunoEngineering Inc. (CPMV)

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Last Post: 5/10/2022 5:08:26 PM - Followers: 255 - Board type: Free - Posts Today: 0

About the incoming Merging Entity - Mosaic ImmunoEngineering Inc. https://www.mosaicie.com/about


Current Programs


MOSAIC LEADERSHIPhttps://www.mosaicie.com/leadership


KEY PUBLICATIONS AND GRANTS - https://www.mosaicie.com/publications




MOSAIC ENGINEERING RECENT NEWS
 

Mosaic ImmunoEngineering Inc. signs license-option to advance novel immunotherapy to treat cancer and infectious diseases


https://thedaily.case.edu/mosaic-immunoengineering-inc-signs-license-option-to-advance-novel-immunotherapy-to-treat-cancer-and-infectious-diseases/

Agreement with CWRU Technology Transfer Office and Dartmouth College
Mosaic ImmunoEngineering Inc., a private biotechnology company based in Novato, California, has signed a two-year option agreement with Case Western Reserve University and Dartmouth College, granting the company the exclusive right to license technology for a novel platform technology using virus-like nanoparticles (“VLP”) to treat and prevent cancer and infectious diseases in humans and for veterinary use.

The technology has broad potential to treat many different types of cancer and is supported by numerous scientific publications and grant funding. The technology also has direct application as part of a vaccine platform, which has generated promising data in both cancer and infectious diseases, including COVID-19, through research funded by the National Science Foundation (NSF).

An option agreement provides Mosaic two years to obtain a full license agreement. A license option typically is granted to a company interested in further evaluation of the technology before entering into a full license agreement that allows the company to commercially market it. The two-year option to license agreement, is managed through Case Western Reserve’s Technology Transfer Office.

“Along with providing world-class research in many areas, Case Western Reserve University and Dartmouth College are striving to translate these exciting discoveries into products that can make a difference in the lives of patients with life threatening illnesses,” said Wayne Hawthorne, senior licensing manager in the university’s Technology Transfer Office. “We encourage our faculty to conduct basic research which can become the basis of discoveries that have direct application to clinical needs such as the technology that Mosaic is seeking to advance. Considerable research and progress was made on the technology through internal awards and grants that funded early product development and clinical proof from organizations such Coulter Foundation, Council to Advance Human Health and Ohio Third Frontier Technology Validation and Start-Up Fund.”

The inventors of the technology include Nicole Steinmetz, professor in the Department of NanoEngineering and director of the Center for Nano-ImmunoEngineering at the University of California San Diego (UCSD), and Jonathan Pokorski, associate professor in the Department of NanoEngineering at UCSD. During their tenure at Case Western Reserve, they worked in conjunction with Steven Fiering, a professor of microbiology and immunology at Dartmouth Geisel School of Medicine.

The researchers have collectively demonstrated that plant-derived, engineered VLP-based nanotechnologies stimulate a potent anti-tumor immune response in mouse models of metastatic melanoma, ovarian cancer, colon cancer, brain cancer and breast cancer, including companion dogs with metastatic melanoma. This data supports the potential to translate preclinical studies into veterinary applications, such as the treatment of cancer in companion animals, which has high relevance to human melanoma.

“We are pleased to have completed this agreement with CWRU and Dartmouth, and look forward to working closely with the university and Drs. Steinmetz, Pokorski and Fiering to rapidly advance the highly promising technology platforms into the clinic,” said Steven King, co-founder and chief executive officer of Mosaic. “This technology platform includes many opportunities in oncology and infectious diseases, including both human and veterinary applications. This is a very important milestone for Mosaic, and we are very happy to have the opportunity to work with prestigious universities and an impressive team of scientists.”

“This immuno-oncology approach provides a personalized treatment approach by relieving the patient’s tumor-mediated immunosuppression and potentiating anti-tumor immunity against antigens expressed by their own tumor,” said Steinmetz, a co-inventor of the technology and a co-founder and chief scientific officer of Mosaic. “The vaccine platform is a natural extension of the immune-stimulating properties of the VLP, combined with directing the response to pre-defined targets. Instead of being a personal vaccine, the modular approach of linking disease specific targets to the VLP allows the potential to rapidly develop countermeasures for pandemics such as COVID-19.”

Mosaic, through its founding team, has identified a lead oncology candidate for advancement into clinical trials and the ongoing NSF funded research is supporting the application of the technology toward the development of a SARS-CoV-2 vaccine for the prevention of COVID-19. Over the past 10 years, the technology has been funded through numerous research grants totaling more than $20 million.

For more information, contact Bill Lubinger at william.lubinger@case.edu.
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#23230   Quarterly is out. EOM. potofgold 05/10/22 05:08:26 PM
#23229   news link: https://www.accesswire.com/700267/Mosaic-ImmunoEngineering-Announces-Completion-of-Exclu potofgold 05/05/22 11:58:44 AM
#23228   scam!! Watch out..don't get sucked in@! Ubgood 03/03/22 06:31:35 PM
#23227   Just now seeing news article link. https://www.accesswire.com/686872/Newly-Publi potofgold 03/03/22 12:10:34 PM
#23226   This stock is a SCAM ALERT!! ITS 10TIMES Ubgood 02/25/22 06:24:02 PM
#23225   This stock is a SCAM ALERT!! ITS 10TIMES Ubgood 02/25/22 06:24:00 PM
#23224   This stock is 10x over valued at this Ubgood 02/23/22 09:13:44 PM
#23223   Your pot is full..the crap this company and Ubgood 02/23/22 09:12:29 PM
#23222   I don't have a link but I'm seeing potofgold 02/23/22 04:46:07 PM
#23221   Only scam here is the company itself!! Total fraud!! Ubgood 02/08/22 07:41:54 PM
#23220   Low share.price...BLAME THE MARKET MAKERS! They are supposed Neverending 02/08/22 05:19:15 AM
#23219   I wouldn't believe anything this scam was a Ubgood 02/03/22 11:25:35 AM
#23218   Just now seeing and reading this news link. potofgold 02/02/22 12:19:29 PM
#23217   One has to wonder who the investors are Ubgood 02/01/22 12:52:39 PM
#23216   One has to wonder who the investors are Ubgood 02/01/22 12:52:38 PM
#23215   Still very very over valued!! No higher..5 cents Ubgood 01/31/22 11:44:07 AM
#23214   Stay smart..stay away from this scam!! Ubgood 01/28/22 06:51:18 PM
#23213   Company directors involved in the same type of Ubgood 01/27/22 07:32:12 PM
#23212   Company directors involved in the same type of Ubgood 01/27/22 07:32:10 PM
#23211   Another thing I found interesting from the annual report: potofgold 01/26/22 02:43:38 PM
#23210   here is something I found interesting from the potofgold 01/26/22 02:40:17 PM
#23209   The track record over the past 10..15..years should Ubgood 01/26/22 08:34:48 AM
#23208   So over valued here for a scam!! Ubgood 01/20/22 06:45:13 PM
#23207   So over valued here for a scam!! Ubgood 01/20/22 06:43:50 PM
#23206   True value here is 5 cents or less!@ Ubgood 01/14/22 06:49:09 AM
#23205   This company had a great teacher in fraud Ubgood 01/10/22 04:50:22 PM
#23204   Mm's aren't doing nothing to the fraud..scam...its true Ubgood 01/04/22 01:17:06 PM
#23203   The evil MMs are.keeping.the price down. CRIMINALS! (in Neverending 01/03/22 02:29:34 PM
#23202   very very over valued here!! Ubgood 12/28/21 01:33:07 PM
#23201   On it's way to 5 cents...true value...or is Ubgood 12/23/21 04:17:10 PM
#23200   SCAM ALERT!! investors finally seeing it for Ubgood 12/15/21 02:16:19 PM
#23199   Pump pump pot o crap!! Ubgood 12/15/21 10:40:59 AM
#23198   The Price, Bid & Ask are some interesting numbers. potofgold 12/14/21 05:25:28 PM
#23197   Only 96 cents more to drop before true value!! Ubgood 12/14/21 12:37:36 PM
#23196   Way over valued for a 5 cent stock!!! Ubgood 12/13/21 06:33:16 PM
#23195   Pure garbage Ubgood 12/11/21 09:45:18 AM
#23194   Only thing here criminal is this company and Ubgood 12/08/21 10:38:13 AM
#23193   The MMs r keepin us down! Criminals! Neverending 12/07/21 06:16:25 PM
#23192   The MMs r keepin us down! Criminals! Neverending 12/07/21 06:16:25 PM
#23191   A FIVE CENT STOCK TRADING AT 1.25....FORGET THIS SCAM!! Ubgood 12/06/21 05:05:23 PM
#23190   Scam alert!!!!!!!!!! Ubgood 12/03/21 06:40:25 PM
#23189   Scam alert!!!!!!!!!! Ubgood 12/03/21 06:40:24 PM
#23188   Someone said the true value here is around Ubgood 12/02/21 04:46:15 AM
#23187   Potofcrap is spreading manure all over this board...scam Ubgood 11/30/21 09:23:52 AM
#23186   I thought CPMV's financial calendar was made to potofgold 11/29/21 03:34:43 PM
#23185   Partial day as we come off an American holiday. potofgold 11/26/21 02:23:55 PM
#23184   Whale buying is back!! Buy before this scam Ubgood 11/17/21 09:49:03 AM
#23183   The scam continues here!!! Ubgood 11/16/21 04:48:37 PM
#23182   Whale buying here..4 shares on this fraud Ubgood 11/15/21 10:29:23 AM
#23181   Whales are moving in here..two players now..164 shares..82 Ubgood 11/12/21 11:52:07 AM
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