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Medgenics (MDGN)

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Last Post: 10/12/2016 1:40:53 PM - Followers: 5 - Board type: Free - Posts Today: 0

Unlocking The Potential Of Gene Theraphy For Patients With Rare And Orphan Diseases....

About Medgenics, Inc.

Medgenics is developing TARGT™ (Transduced Autologous Restorative Gene Therapy), a proprietaryex vivo gene therapy platform for the sustained production and delivery of therapeutic proteins and peptides using a patient's own tissue, for the treatment of rare and orphan diseases. For more information, visit the Company's website at

Our core strategy is based upon three fundamental strengths:

Strive for unparalleled understanding of the underlying science of rare diseases, from genotype to phenotype for each patient

  • Focused on developing “best-in-class” therapies that are life altering for our patients
    Capable of crossing scientific boundaries for new and better therapies where none existed before
    Centered around a capital-efficient platform that holds the potential to increase the speed of development
    Able to produce proteins, peptides, and other molecules
    Experienced and successful drug developers
    Demonstrated track record of guiding novel medicines to patients
    Driven to collaborate with our patients and advocacy groups to increase awareness and commitment to research, and improve access to therapies



Transduced Autologus Restorative Gene Theraphy


1. Harvest Micro-Organs from abdominal dermis using the proprietary DermaVac device

2. Transduce fibroblasts in Micro-Organs via ex vivo gene therapy to create TARGTEPO

3. Wash out HDAd vector, measure production and choose TARGTEPO for re-implantation
4. Implant TARGTEPO into patient where it produces endogenous EPO (eEPO)   






  • Closely mimics natural system, creating restorative treatment paradigm
    Improved durability in vivo
    Greater cell uptake
    Less immunogenicity
  • Ex vivo transduction eliminates patient exposure to viral vectors typically seen in gene therapy
    Reduced chance of developing neutralizing antibodies which can lead to reduced efficacy and anaphylactic reactions
    Ability to control dosing through the addition and removal of micro-organs as needed
    Implantation ensures compliance and better outcomes, and provides control of the product
  • Exogenous gene therapy on “tummy tuck” tissue is performed to testhuman protein expression in vitro
    Severe combined immunodeficient (SCID) mice provide predictive in vivomodel for protein expression and duration
    In vitro (human) and in vivo (SCID mouse) models provide 
    pre-clinical POC, for approximately $100K and less than 6 months
    Platform eliminates the need for large investment in manufacturing and scale up for clinical trial material


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#125   Medgenics Files An 8-K trendmkr 10/12/16 01:40:53 PM
#124   Medgenics (MDGN): Turning Over a New Leaf with BollixMeArse 10/07/16 11:04:13 AM
#123   MDGN bullish 5.67 stocktrademan 07/01/16 11:55:09 AM
#122   Medgenics enters collaboration with Kyowa Hakko Kirin for BollixMeArse 06/06/16 10:44:00 AM
#121   Sub $5... I have to add at this level! BollixMeArse 01/08/16 10:36:31 AM
#120   Medgenics Licenses Novel GeneRide Gene Therapy Technology From BollixMeArse 01/07/16 10:10:01 AM
#119   Mr. Isaac Blech's (Director) Share Sale Timing & Details. BollixMeArse 10/01/15 01:57:34 AM
#118   $MDGN recent news/filings stocktrademan 09/14/15 03:59:03 PM
#117   MDGN: neuroFix Acquisition Could Be A Needle-Mover BollixMeArse 09/14/15 10:39:01 AM
#115   Medgenics Awarded $3.4 Million Grant From the Israeli BollixMeArse 06/11/15 09:36:21 AM
#114   Kudos to the new management for choosing the BollixMeArse 05/06/15 10:57:07 AM
#113   You should've bought MDGN when you had the chance. stockspikes 04/13/15 04:52:47 PM
#112   Medgenics Receives New Coverage from Analysts at JMP BollixMeArse 04/13/15 11:50:30 AM
#111   Q4 2014 Medgenics Inc Earnings Presentation PDF (LINK) BollixMeArse 02/13/15 09:28:41 AM
#110   Should You Purchase Medgenics After Its Recent Run Up? BollixMeArse 01/29/15 12:59:12 PM
#109   I've held MDGN for over 3 Years and BollixMeArse 01/22/15 07:04:15 PM
#108   MDGN: Positive MDGN-201 Data Through 7 Months BollixMeArse 01/16/15 02:01:58 PM
#107   Link To PDF of Biotech Conference Presentation 1/13/15: BollixMeArse 01/14/15 07:28:07 AM
#106   Question on Hep C / IFN-a therapy: How dubbya 12/22/14 09:33:13 PM
#105   Medgenics CEO Cola Buys 60,976 Shares @$4.10/Share BollixMeArse 12/02/14 09:48:12 AM
#104   Medgenics to Present at 26th Annual Piper Jaffray BollixMeArse 11/26/14 08:11:26 AM
#103   Great News! BollixMeArse 11/26/14 08:09:43 AM
#102   I'm either a fool or a wise man... BollixMeArse 11/12/14 11:42:03 PM
#101   New Positive Clinical Data Supports Quest Towards Orphan Designations BollixMeArse 10/17/14 08:14:07 AM
#100   Medgenics to Present Initial Clinical Data From MDGN-201 BollixMeArse 10/07/14 09:27:51 AM
#99   Big Volume, Big Gain... Why? BollixMeArse 10/06/14 02:28:05 PM
#98   MDGN: Trial / Development Timelines Remain On-Track BollixMeArse 07/18/14 08:31:44 AM
#97   Medgenics Announces Global Head, Research and Development, Garry BollixMeArse 06/18/14 09:43:55 PM
#96   More insider buying. BollixMeArse 06/17/14 11:15:59 AM
#95   Medgenics to Present at Two Upcoming Healthcare Investor Conferences BollixMeArse 06/16/14 10:40:42 AM
#94   Medgenics Looking To Exploit Orphan Drug Market With BollixMeArse 06/14/14 07:45:14 AM
#93   Medgenics [$MDGN] due dilligence stocktrademan 06/13/14 01:55:32 PM
#92   Medgenics Announces First Patient Implanted in Phase 1/2 BollixMeArse 06/05/14 06:02:21 PM
#91   Medgenics director just picked up 60,000 shares BollixMeArse 05/13/14 08:55:46 AM
#90   Medgenics Reports First Quarter Financial Results BollixMeArse 05/08/14 11:39:47 AM
#89   Medgenics awarded $2.2 mln grant from the Israeli BollixMeArse 04/15/14 09:12:27 AM
#88   What are the terms of the warrants? meltup 02/08/14 04:55:08 PM
#87   No News = 10% gain and 3 X BollixMeArse 01/31/14 07:02:12 AM
#86   GALT, CNAT, ICPT, & MEDGENICS (MDGN) treat liver meltup 01/09/14 01:52:18 PM
#85   Medgenics director just picked up 7,000 shares BollixMeArse 01/07/14 06:49:58 PM
#84   You beat me to it with your question. RVL 01/02/14 05:23:13 PM
#83   8% Afternoon Bump On Above Average Volume. No BollixMeArse 01/02/14 05:13:32 PM
#82   Medgenics announced Director entered into stock trading plan BollixMeArse 12/24/13 08:34:51 AM
#80   INSIDER BUYING CONTINUES!!! BollixMeArse 12/18/13 09:32:13 AM
#79   Another 20K Insider Buy at 5.37 BollixMeArse 12/16/13 09:44:29 AM
#78   Medgenics to Present at the Oppenheimer 24(th) Annual BollixMeArse 12/04/13 10:33:52 AM
#77   Medgenics Reports Open Market Purchase of Common Stock BollixMeArse 12/03/13 09:01:49 AM
#76   Another 25,000 shares bought at market for Sol Barer. AtlasSnuggled 11/13/13 10:10:21 AM
#75   SolBarer buys addn'l 20Kshares 1day AtlasSnuggled 09/22/13 11:35:16 PM