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Created: 07/25/2008 05:14:55 PM - Followers: 646 - Board type: Free - Posts Today: 0

INOVIO'S Impressive pipeline

Inovio's 86,851,493 shares of common stock outstanding as of December 31, 2020

Inovio Selected by CEPI to Develop Vaccine Against New Coronavirus
9:15 AM ET 1/23/20 | PR Newswire

PLYMOUTH MEETING, Pa., Jan. 23, 2020 /PRNewswire/ -- Inovio Pharmaceuticals, Inc. (NASDAQ:INO) today announced the Coalition for Epidemic Preparedness Innovations (CEPI) has awarded Inovio a grant of up to $9 million to develop a vaccine against the recently emerged strain of coronavirus (2019-nCoV) that has killed numerous people and infected hundreds more in China to date. This initial CEPI funding will support Inovio's preclinical and clinical development through Phase 1 human testing of INO-4800, its new coronavirus vaccine matched to the outbreak strain. CEPI previously awarded Inovio a grant of up to $56 million for the development of vaccines against Lassa fever and Middle East Respiratory Syndrome (MERS), also caused by a coronavirus.

Inovio's participation in this developing effort is based on the ideal suitability of its DNA medicine platform to rapidly develop a vaccine against an emerging virus with pandemic potential, proven vaccine development capabilities and a strong track record of rapidly generating promising countermeasures against previous pandemic threats. Inovio was the first to advance its vaccine (INO-4700) against MERS-CoV, a related coronavirus, into evaluation in humans. Inovio is currently preparing to initiate a Phase 2 vaccine trial for INO-4700 in the Middle East where most MERS viral outbreaks have occurred.

In a recently published paper in Lancet Infectious Diseases, Inovio's Phase 1 study of its MERS-CoV vaccine demonstrated it was well tolerated and furthermore induced high levels of antibody responses in roughly 95% of subjects, while also generating broad-based T cell responses in nearly 90% of study participants. Durable antibody responses to INO-4700 were also maintained through 60 weeks following dosing.

Richard Hatchett, CEPI's CEO, said, "Given the rapid global spread of the 2019-nCoV virus the world needs to act quickly and in unity to tackle this disease. Our intention with this work is to leverage our work with Inovio on the MERS coronavirus and rapid response platform to speed up vaccine development."

Dr. J. Joseph Kim, Inovio's President & CEO said, "We're extremely honored to expand our partnership with CEPI to tackle this new threat to global public health. Our DNA medicine platform represents the best modern day approach to combatting emerging pandemics. We have already demonstrated positive clinical outcomes with our vaccine against MERS-CoV, another coronavirus. Importantly, following the Zika viral infection outbreak, Inovio and our partners developed a vaccine that went from bench to human testing in just seven months -- the fastest vaccine development on record in recent decades. We believe we can further improve upon this accelerated timeline to meet the current challenge of the emerging Chinese coronavirus 2019-nCoV."

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ASCO 2022 Abstract REGN and INO. Opus X 05/27/2022 01:38:50 AM
Information for new readers/investors which should do their Tamtam 11/09/2021 06:10:04 PM
Inovio has no "vaccine". A vaccine implies something MiamiGent 01/29/2020 12:18:32 AM
INO My message to the SEC, if they MiamiGent 07/05/2022 01:22:12 PM
INO My message to the SEC- "Delist this MiamiGent 07/05/2022 01:19:30 PM
No pump, just possibilities driving " INO" !! smoking guns 07/01/2022 03:02:59 PM
Kate Broderick is no longer an Inovio employee. gew59 06/29/2022 05:21:57 AM
INO Hopefully Inovio will be doing the honorable MiamiGent 06/22/2022 04:12:22 PM
This is probably the worst Nasdaq stock I radly 06/16/2022 05:04:16 PM
INO will cure Monkey Pox any day now. ADXSINC 06/16/2022 11:56:52 AM
INO Posted on 6/2/22, Updated 6/16/22 MiamiGent 06/16/2022 11:14:07 AM
INO The link below is of past Inovio MiamiGent 06/15/2022 12:34:55 PM
INO Here is an Inovio insight for people MiamiGent 06/12/2022 09:14:05 PM
INO Need another hint? MiamiGent 06/11/2022 08:28:25 AM
$INO Look at this chart and see where MiamiGent 06/11/2022 08:24:05 AM
INO Question asked: MiamiGent 06/11/2022 08:22:24 AM
INO MiamiGent 06/10/2022 10:07:58 AM
INO ...... Moderna (MRNA) said Wed. that its MiamiGent 06/08/2022 11:38:35 AM
$INO A message to newbees, do your own research smoking guns 06/07/2022 11:23:27 PM
$INO A message to newbees: MiamiGent 06/06/2022 09:27:40 PM
Buyout? This is so FOS. MiamiGent 06/04/2022 11:03:54 AM
Here is the link I want to provide MiamiGent 06/03/2022 01:30:45 PM
INO This pumping talk of "buyout" is totally MiamiGent 06/01/2022 01:12:57 PM
INO Of course someone serving as a board MiamiGent 05/31/2022 08:04:20 PM
INO WARNING: STAY AWAY FROM INOVIO MiamiGent 05/31/2022 07:49:25 PM
DISCLAIMER The Board Assistants herewith, are not licensed Tamtam 05/31/2022 07:02:20 PM
Great news, lol radly 05/31/2022 02:16:30 PM
INO Long time Pump & Dump. MiamiGent 05/31/2022 12:45:56 PM
LOL I now wish for WHO to announce positive Opus X 05/27/2022 10:25:00 PM
Your wish came true Opus! spartex 05/27/2022 05:50:38 PM
ASCO 2022 Abstract REGN and INO. Opus X 05/26/2022 09:38:50 PM
Back to garbage status, where this belongs. steadykickin 05/25/2022 08:51:13 PM
INO What does this have to do with Inovio? MiamiGent 05/24/2022 06:45:46 PM
ever heard of biologic warfare? you don't tell doc2016 05/24/2022 10:48:33 AM
INO But not with Inovio. MiamiGent 05/22/2022 12:06:46 AM
More biotech mergers and acquisitions Opus X 05/21/2022 01:10:07 PM
Inovio Pharmaceuticals Says There Has Been No Further gew59 05/21/2022 10:58:04 AM
I don’t see monkey or smallpox in their gew59 05/19/2022 01:18:32 PM
Guess that is why it is up so desarcmo 05/19/2022 01:01:36 PM
They already have one. From 2010 gew59 05/19/2022 10:45:18 AM
I hear INO can create a vaccine for desarcmo 05/19/2022 10:43:03 AM
Way off? Sold in high twenties! If making surfnsk8 05/18/2022 12:09:50 PM
INO Why is he getting continual stock options? MiamiGent 05/18/2022 09:56:13 AM
To pay the tax’s on his options! Wow surfnsk8 05/18/2022 09:42:58 AM
INO Inovio Insider David B. Weiner sold shares MiamiGent 05/18/2022 09:05:58 AM
INO You edited my sentence, cutting off, "in MiamiGent 05/17/2022 09:46:47 AM
INO "Hostile takeover" LOL MiamiGent 05/15/2022 02:29:19 PM
INO Buy what? Inovio has nothing. MiamiGent 05/15/2022 02:05:21 PM
INO What?? MiamiGent 05/15/2022 01:59:22 PM
INO "It's All Over" MiamiGent 05/15/2022 01:44:08 PM
Strong Candidate for Acquisition Opus X 05/15/2022 08:44:15 AM
A fair assessment. Thanks for posting gew59. MiamiGent 05/14/2022 08:37:13 PM
A good summary. ……. gew59 05/14/2022 07:53:25 AM
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