[Preciouslife1]

https://www.linkedin.com/feed/update/urn:li:activity:7136059475848798209?utm_source=share&utm_medium=member_ios

[cowtown jay]

I think the only Bufferin that could be required would be for Durrant, trying to satisfy parties of interest to this filing.

I think it's a static sight, and there is no data compilation needed, so buffering is not an applicable consideration.

Here's a link to the site.

https://www.sec.gov/cgi-bin/browse-edgar?company=humanigen&match=starts-with&filenum=&State=&Country=&SIC=&myowner=exclude&action=getcompany

I've been monitoring this site several times each day, for multiple companies, for many years. I've never seen anything like this before.

[TankTheFrank]

Any chance it is just an error when the web page was buffering? I would recommend checking the page's script to see if there was an error.

[cowtown jay]

As our latest Form 4 continues to disappear and reappear, even this morning, we may need to consider who the beneficiary of these shares may be. Baudax is still a contender. But another possibility may be that Novavax will receive these shares in a stock-for-stock merger agreement.

I say that for two new reasons. First, Novavax announced approval of their standard vaccine in South Korea just days ago.

https://ir.novavax.com/press-releases/Novavaxs-Updated-COVID-19-Vaccine-Receives-Emergency-Use-Authorization-in-the-Republic-of-Korea

And we know that S. Korea conducted a safety trial of Humanigen's lenzilumab some time ago.

https://ir.humanigen.com/English/news/news-details/2021/Humanigens-Partner-in-South-Korea-Receives-Ministry-of-Food-and-Drug-Safety-MFDS-Approval-to-Conduct-Phase-1-Study-of-Lenzilumab/default.aspx

In addition, the WHO's Emergency Use Listing (EUL) approval of the standard Novavax vaccine was based on non-clinical data.

However, in regards to Novavax's prototype vaccine, "In clinical trials, the most common adverse reactions associated with Novavax's prototype COVID-19 vaccine (NVX-CoV2373) included headache, nausea or vomiting, muscle pain, joint pain, injection site tenderness, injection site pain, fatigue and malaise." It would likely have been the prototype vaccine that used lenz as an adjuvant.

It would be very exciting to see news in this regard, if my assumption about incorporating lenz in the prototype vaccine is correct.

[10nisman]

<<< Nice move. I've got over 35k between 53 and 60. It's just a waiting game. The company is obviously not worthless. >>>
Obviously. SMH.

[cowtown jay]

I can't find the specific post I need to clarify the status of the various trials, but I found something close. I believe the person I contacted was with the IMPACT group, conducting the RATinG study of aGvHD.

"IMPACT is going to do an interim assessment of the first 20 patients who get enrolled in their 18 treatment centers.

"The first stage of the trial is expected to treat 20 participants with lenzilumab before conducting an interim assessment of safety, efficacy, and feasibility."

https://ir.humanigen.com/English/news/news-details/2023/Humanigen-Announces-First-Participant-Dosed-in-RATinG-Trial-of-Lenzilumab-for-Early-Treatment-of-Acute-Graft-Versus-Host-Disease-Following-Allogeneic-Stem-Cell-Transplantation/default.aspx

So it may not take long for the data monitoring committee to collect and review data from 20 patients, from 18 sites, and making a recommendation to a second trial stage. Maybe we'll hear something about that CMML patient who progressed to needing aGvHD to be cured of his cancer."

https://investorshub.advfn.com/boards/read_msg.aspx?message_id=172695604

So I hope we will hear more from this trial.

[cowtown jay]

"And give that discretionary authority to the pharmaceutical companies to self regulate?"

Um, no. I think Self Regulatory Organizations (SRO's) should also be banned.

I totally agree with you, sosjtb, that, "...regulations exist for a reason..." And they should be enforced. There should be no discretionary authority invested in the offices of unelected bureaucrats to ignore the laws created by the elected legislators. NONE. These agencies should follow the laws, as written, unless the legislators change the law.

[sosjtb]

And give that discretionary authority to the pharmaceutical companies to self regulate?

No thanks, we know their drive isn’t altruistic but for the benefit of shareholders as their number one driving force. The government is the backdrop to that. It ain’t perfect for sure, but regulations exist for a reason and profit driven regulations are never in the interest of our population as a whole.

[cowtown jay]

“As a seasonal slew of respiratory illnesses circulate, it’s Covid that continues to send the most people to the hospital, the Centers for Disease Control and Prevention said Friday.

Covid is still the primary cause of new respiratory virus hospitalizations and death,” CDC Director Dr. Mandy Cohen said at a briefing for reporters Friday.

The virus is responsible for about 15,000 hospitalizations and 1,000 deaths every week, she said."

https://www.yahoo.com/news/covid-drives-hospitalizations-across-country-120000797.html

How many of these hospitalizations and deaths will lenz and the lenz vaccine cocktail prevent? At the least, this is willful negligence by government regulators to approve lenz. Those who are personally benefitting by maintaining the status quo in regards to authorizations and approvals could be guilty of criminal negligence. This includes, but transcends, the remedy of medical license revocation. These people should be arrested, tried, and sentenced for their corruption.

We have got to rescind discretionary authority from government agencies.

[sosjtb]

Right wing nut job conspiracy theories aren’t designed to over complicate things, they are designed and created to appeal to the dumbest among us. It’s simple thoughts without real evidence to help people make sense of things they can’t understand. It helps them feel better about themselves when they think they know better than others…

One of the best ways to recognize a nut job is one who runs away from the debate, ignores the controversy and hides away in their little bubble of ignore when faced with contradictory information to their low information view set fed by other nut jobs on Tv pushing for ratings and social media clicks.

Carry on…

[Preciouslife1]

TANKTHEFRANK; I AM NOT OVER COMPLICATING ANYTHING!!!!! GAIN OF FUNCTION RESEARCH SPONSORED AND PAID FOR BY THE NAIAD, NIH, RUN BY FAUCI MERGED TWO VIRUSES AS IN CORONAVIRUS AND SARS2 ALONG WITH OTHER UNSCRUPULOUS ADDITIVES TO INCREASE MUTATIONAL ABILITIES AND TOXICITY AS A BIOENGINEERED, BIO-TERROR WEAPON THAT GOT OUT; FROM THE BIO LAB IN WUHAN CHINA ... IF THAT IS OVERCOMPLICATING THINGS MAYE YOUR UNDERSTANDING IS THE FAULTY ASPECT WITH NO INSULT INTENDED ... I ALMOST DIED FROM CV19, WHICH BYPASSED ALL RESPIRATORY AND WENT RIGHT FOR ANY PREVIOUS WEAKNESSES & IN MY CASE PRIOR LIVER AND KIDNEY CANCER ... SO OVERCOMPLICATING THINGS??? NAH I DON'T THINK SO ..... CIAO

[sosjtb]

A retired chiropractor in a tin foil hat without any prescriptive authority doesn’t seem to understand that FDA approval for use of medications comes with conditions on the use of those medications.

Whack jobs talking about ivermectin as if it’s approved for use in all medical conditions instead of Lice and Scabies and other parasitic infections clearly show they don’t know what the F they are taking about. Including the optometrist going after a highly regarded and accomplished Dr of infectious disease to make political points lol.

Facebook and social media warriors are the key drivers in the dumbing down of America. Just because someone says something you agree with, that doesn’t make it true enough to validate your preconceived perceptions on an issue!

Also there are no short sales in HGEN since the volume is ridiculously low for any MM to take advantage of that at the moment and the only thing US retail can do is put out sell orders.

[cowtown jay]

I can see where Fauci should be allowed to practice medicine...at a Mens' Federal Medical Center prison.

[TankTheFrank]

It is more important if the claims leveled are true that he stop receiving the privileged decision making ability with peoples lives that a doctor gets, ie hit with medical multi malpractice suit and license revocation rather than trying to put a system in place when there is already something there to manage doctors.

[TankTheFrank]

There is a hippocratic oath that is sworn upon becoming a doctor. If Faucci knowingly violated this Hippocratic oath he should be placed under medical board review and they if upon reviewing and validating these claims against him should likely strip him of his ability to practice medicine if true. Easy as that Precious. Don't over complicate.

[cowtown jay]

For the first time since June, I'm seeing data reported by the 'Short Volumes' website regarding Humanigen's stock. For the last session, they reported, "The short sale volume percent (not short interest) for stock ticker HGEN is 68.45% on Dec 01, 2023. The short sale volume is 60,256. The total volume is 88,027. The short sale volume percent is up 68.29% compare to Nov 30, 2023."

http://shortvolumes.com/?t=HGEN

I don't know if Humanigen is providing 'locates' for these short positions, but being on the Expert Market, I don't know who else would. Is this preparatory for the recall of our loaned shares?

Also, the price chart displays data for Hydrogenome Capital Growth, which trades on the London exchange with the ticker HGEN.L. It should not be displayed on Humanigen's site.

In the event that the displayed data is removed, this is what is currently showing for the past 10 days.

The Volume and short volume are limited. It is not including all volumes from all Market.
Date Short Volume Total Volume Percent
2023-12-01 60,256 88,027 68.45%
2023-11-30 98 61,710 0.16%
2023-11-29 16,738 56,449 29.65%
2023-11-27 10 9,803 0.1%
2023-11-20 170 64,808 0.26%
2023-11-17 42,300 52,728 80.22%
2023-11-16 5,800 42,895 13.52%
2023-11-15 100 19,000 0.53%
2023-11-14 370 34,653 1.07%
2023-11-13 55,924 61,677 90.67%

Posters' opinions can be expected to be right or wrong. But it is definitely not nice for a reporting website to display inaccurate information that needlessly confuses an old man trying to maintain some semblance of his mental faculty. And yes, I resemble that remark.

I just hope the accurate portion of this data display portends the imminent recall of our loaned shares.

[Preciouslife1]

📸 Look at this post on Facebook https://www.facebook.com/share/v/v7KdcdSY1BQVhS2K/?mibextid=WC7FNe
GAIN OF FUNCTION RESEARCH IS CRIMINAL AND IMMORAL WHEN NOT SECURITIZED

[shajandr]

This says it all:

[cowtown jay]

Interesting, isn't it, that the FDA cleared Gracell's 'GC012F' CAR-T IND application on Nov 27th, and then the next day, they announced that they were investigating the cancer risks linked to CAR-T therapy?

https://investorshub.advfn.com/boards/read_msg.aspx?message_id=173299876

https://investorshub.advfn.com/boards/read_msg.aspx?message_id=173316333

Humanigen's latest patent, dated in June of this year, was to improve the, "Method of increasing the efficacy of CAR-T immunotherapy using lenzilumab
Patent number: 11673962..."

https://patents.justia.com/assignee/humanigen-inc

Is Gracell realizing the reduced toxicities achieved by using lenz in their CAR-T, as described in our patent? Has this opened the eyes of the FDA to the avoidable adverse consequences of other CAR-T's?

Is there hope that using lenz as a covid vaccine adjuvant, which Humanigen has also patented, is yielding the same success for the prototype Novavax vaccine?

[F/T]

Thank you for posting.

[cowtown jay]

Thanks for sharing this link, Tank. It was great to see this receive journal publication ahead of the ASH conference in regards to the PREACH-M study. Although I admit that I enjoyed Dr. Thomas' interviews far more on this subject. His excitement was contagious!

Newtg's article was in regards to lenzilumab representing the 4th arm of the C-SMART trial, which I think we pulled out of when the Australian government declared an end to the prioritization of covid trials.

I'm eagerly awaiting further updates on the aGvHD trial, after the first person was dosed and, as I recall, showed no continuing signs of CMML cancer.

for future reference:

https://ashpublications.org/blood/article/142/Supplement%201/1847/505640/Lenzilumab-in-Addition-to-Azacitidine-Improves

https://www.anzctr.org.au/TrialSearch.aspx#&&conditionCode=&dateOfRegistrationFrom=&interventionDescription=&interventionCodeOperator=OR&primarySponsorType=&gender=&distance=&postcode=&pageSize=20&ageGroup=&recruitmentCountryOperator=OR&recruitmentRegion=ðicsReview=&countryOfRecruitment=®istry=&searchTxt=Lenzilumab&studyType=&allocationToIntervention=&dateOfRegistrationTo=&recruitmentStatus=&interventionCode=&healthCondition=&healthyVolunteers=&page=1&conditionCategory=&fundingSource=&trialStartDateTo=&trialStartDateFrom=&phase=

[TankTheFrank]

https://ashpublications.org/blood/article/142/Supplement%201/1847/505640/Lenzilumab-in-Addition-to-Azacitidine-Improves

[Preciouslife1]

https://www.newsweek.com/pfizer-vaccine-lawsuit-ken-paxton-maga-1848769

[cowtown jay]

"Pfizer is sued by Texas over COVID vaccine claims
Jonathan Stempel...
Updated Thu, November 30, 2023

(Reuters) - Pfizer has been sued by Texas Attorney General Ken Paxton, who on Thursday accused the drugmaker of misrepresenting the efficacy of its widely-used COVID-19 vaccine.

In a complaint filed in a Lubbock County state court, Paxton said it was misleading for Pfizer to claim its vaccine was 95% effective because it offered a "relative risk reduction" for people to who took it.

Paxton said the claim was based on only two months of clinical trial data, and vaccine recipients' "absolute risk reduction" showed that the vaccine was just 0.85% effective.

https://www.yahoo.com/news/pfizer-sued-texas-over-covid-204834093.html

[cowtown jay]

There's a 30 degree temperature range forecasted here (Fort Worth, TX area) tomorrow, not too unusual. And Warren is only about 20 miles from my hometown of Youngstown, which I left after high school to join the Army.

But those temperature patterns have been consistent forever. I don't see any reason for those temperature ranges to all of a sudden be responsible for altering the human immune response system.

The best way to conduct biowarfare is to have your ignorant-ass targeted population further harm themselves with their own medical countermeasures. There's only so much you can alter the immune response system, before it is no longer capable of defending us. There's nothing common about a disease, or the treatments, that alters the immune response system.

I find it very suspicious that this phenomenon isn't being studied on a vaccinated vs unvaccinated basis.

[eb0783]

I agree with all of that. I live in Columbus, so we experience all of that.

[TankTheFrank]

Ohio has extreme weather shifts over fall season, a person can see 35 degrees Fahrenheit in the morning or night and around 70+ degrees during the day. People don't plan/dress for the variable weather well and get sick here. Combine this weather flux with family gathering and individuals being stuck inside together increases communicability. What i am saying is read the article with heavy skepticism. The illnesses are common, the children are an age that depends on caregivers to provide weather appropriate clothes and the illness noted are common and communicable with close proximity.

[cowtown jay]

"Ohio faces unprecedented child pneumonia outbreak
Brody Wooddell
Thu, November 30, 2023...

Health experts speculate that reduced exposure to common pathogens during the pandemic lockdowns might have weakened children’s immune systems, making them more susceptible to infections."

https://www.yahoo.com/news/ohio-faces-unprecedented-child-pneumonia-200617438.html

In the post-mass vaccination period, I think that any speculation about the weakened innate immune response system needs to compare patient populations on a vaccinated versus unvaccinated basis. I don't buy that the weakened immune response is due to reduced exposure to pathogens. I'd be interested in reading any studies that support that claim. I think it is more likely that the mRNA vaccines play a large role in altering the innate immune response.

As I have been writing this post, I see that 'Preciouslife1' has just shared a corroborating report from the NY Post regarding an outbreak of child pneumonia in Massachusetts. He provides the following link.

https://nypost.com/2023/12/01/news/massachusetts-records-child-pneumonia-outbreak-cases/

I can only hope that the Novavax prototype vaccine uses the lenz cocktail, and that this protein-based vaccine becomes standard of care in the 194 countries where Novavax is approved, and that we can avoid the self-destruction which only benefits the proponents of mRNA vaccines.

[Preciouslife1]

https://nypost.com/2023/12/01/news/massachusetts-records-child-pneumonia-outbreak-cases/

[GURUBK]

Yes. The stock price for HGEN is not doing so well at the moment.

[Diego Rivas]

Is there some news about hgen and its stock price?

[cowtown jay]

Well, this needs clarification. I know that I had read the Australian New Zealand trial registry you linked before. I may have even previously provided that same link. And I'm fairly certain that I had contacted Dr. Yong in this regard. Plus, I think I saw where Humanigen was no longer testing cancer patients with covid. If we don't get surprised with the announcement of the recall of our loaned shares, I'll look deeper into this.

[Newtg]

Chatter from another board would indicate trial is still going, was recently updated and participation has gone from 7 to 24.

[cowtown jay]

Thank you, Newtg. As I recall, this trial was abandoned once the Australian government deemed that covid no longer posed a public health emergency to cancer patients. I may have even contacted Dr. Michelle Yong regarding this trial. I think management decided to focus on the PREACH-M trial, which looks like it may be the pathway to a cancer cure.

[Newtg]

Not my find. Posted by someone elsewhere.

[Newtg]

Jay - something for you to look at from Australia…

https://www.anzctr.org.au/TrialSearch.aspx#&&conditionCode=&dateOfRegistrationFrom=&interventionDescription=&interventionCodeOperator=OR&primarySponsorType=&gender=&distance=&postcode=&pageSize=20&ageGroup=&recruitmentCountryOperator=OR&recruitmentRegion=ðicsReview=&countryOfRecruitment=®istry=&searchTxt=Lenzilumab&studyType=&allocationToIntervention=&dateOfRegistrationTo=&recruitmentStatus=&interventionCode=&healthCondition=&healthyVolunteers=&page=1&conditionCategory=&fundingSource=&trialStartDateTo=&trialStartDateFrom=&phase=

[cowtown jay]

Mystery respiratory illness developing worldwide.

https://www.yahoo.com/news/dc-area-hospitals-see-uptick-213359373.html

Will these respiratory illnesses, which include pneumonia, progress to cytokine storm? Should we be prepared for that? Remember that lenz showed an 8-fold improvement in treatment outcomes for the Black and African American population.

[cowtown jay]

"FDA investigating cancer risk linked to CAR-T cell therapy
Jonathan Gardner
Updated Tue, November 28, 2023"

https://www.yahoo.com/finance/news/fda-investigating-cancer-risk-linked-154600978.html

Can lenz improve the overall safety profile?

[cowtown jay]

"WHO authorizes emergency use of Novavax's updated COVID shot
Reuters
Updated Tue, November 28, 2023"

https://www.yahoo.com/news/authorizes-emergency-novavaxs-updated-covid-112849432.html

I think authorization of Novavax's prototype vaccine is more relevant to us.

[cowtown jay]

How ridiculous and uninformed it is to think that posting about other companies, whose platforms and drugs will benefit tremendously from lenz, have no bearing on this company. It's understandable that people may think that posting about other companies on this board doesn't belong here. But that only reflects a lack of appreciation of lenzilumab's capability. IN MY OPINION.

Tell that to Gilead, who tried to enhance azacitidine by acquiring '47 Inc.' for $4.9B, for their magrolimab MAB.

"Gilead to Acquire Forty Seven for $4.9 Billion"

https://www.gilead.com/news-and-press/press-room/press-releases/2020/3/gilead-to-acquire-forty-seven-for-49-billion

"Gilead To Discontinue Phase 3 ENHANCE Study of Magrolimab Plus Azacitidine in Higher-Risk MDS"

https://www.gilead.com/news-and-press/press-room/press-releases/2023/7/gilead-to-discontinue-phase-3-enhance-study-of-magrolimab-plus-azacitidine-in-higher-risk-mds

And remember what Humanigen reported from the PREACH-M study of using lenz for CMML, versus Gilead's use of magrolimab.

"PREACH-M trial: Lenzilumab may improve treatment response in chronic myelomonocytic leukemia"

https://www.news-medical.net/news/20230609/PREACH-M-trial-Lenzilumab-may-improve-treatment-response-in-chronic-myelomonocytic-leukemia.aspx

But you can certainly count me in on wanting to see, not just an update, but regulatory recognition and approval of lenz. The issue isn't that management owes us an update, it's that regulators, somewhere in the world, owe Humanigen authorization and approval of lenz.

[All-Bidness]

Not for nothing, posting about other companies has no bearing on this company, and does not belong on this board. If you have news from management please post, if you have articles referring to our drug, please post. The facts are, management owes us an update.