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Hepion Pharmaceuticals, Inc (HEPA)

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Last Post: 7/24/2021 3:01:55 PM - Followers: 95 - Board type: Free - Posts Today: 0


Hepion Pharmaceuticals (Nasdaq: $HEPA) is a clinical stage biopharmaceutical company focused on the development of targeted therapies for liver disease arising from non-alcoholic steatohepatitis (NASH) and chronic hepatitis virus infection (HBV, HCV, HDV).

Hepion announced top line data from the low dose cohort in the Company's Phase 2a ‘AMBITION' clinical trial of CRV431, an oral, once daily novel cyclophilin inhibitor. This Phase 2a study is continuing with the higher dose of 225 mg CRV431, with NASH patient dosing expected to be completed in Q1-2021.In 2021, of the more than 300 million people living with HBV infection, 10.5% (27 million) were aware of their infection. Non-alcoholic Fatty Liver Disease (NAFLD) affects up to 25% of people in the United States. There are currently no medicines that can cure non-alcoholic Fatty Liver Disease effectively. The same can be said with HBV. With the momentum growing around hepatitis B drug discovery research, we are closer than ever to a cure.

Fact: The inflows have been massive the last 2 weeks. Reason why In just 28 days at the low dose, HEPA CRV431 results were as good as what Madrigal's P3 lead NASH drug took 12 weeks to accomplish.

Bottom line The FDA looks for safety first we have the safest NASH drug our efficacy data is better than MDGL & AKRO. there market caps our almost 10x HEPA. Smart savvy biotech investors with deep pockets know this and are accumulating all they can of HEPA at these levels.
One morning we can wake up and see the price has tripled from its 160 market cap. Also they have 120 million in cash burning under 5 million a quarter. Lots of moving parts here. Gilead & Novo in the mix we will see? A new molecule being added to the pipeline. This management team is experienced 100 years total and world renown experts on cyclophilin inhibitors. They brought a FDA approved blockbuster drug to market already.

June 2021 Hepa Biz Presentation

HEPA Tackling Chronic Liver Disease - CRV431 Mechanism of Action


HEPA website

Chairman of the Board, Gary Jacob, is not just a business guy, he's one hell of a biochemist, and you can bet he has a solid grasp of everything that's going on with Hepion.
He's a key player here!

His background goes way beyond what you ordinarily see on the BOD of little R&D biotechs. You might see those with his research background on Scientific Advisory Boards, but they wouldn't have a fraction of the business expertise he's got.
Hepion has the whole package, with this guy!!

Hepion Pharmaceuticals Welcomes Dr. Stephen Harrison to its Scientific Advisory Board

Former Novo Nordisk Executive, Dr. Todd M. Hobbs, Joins Hepion Pharmaceuticals as Chief Medical Officer
Todd Hobbs coming to Hepion. It was published in December. Hobbs' primary focus has always been on diabetes, and I have said many times that there's a blockbuster reason for him leaving his position as Vice President, Chief Medical Officer at Novo Nordisk, a USD 190B global pharmaceutical behemoth, after nearly 17 years there, to come to tiny Hepion.
I believe we'll be hearing about CRV431 in the treatment of diabetes, as it has the highest known potency of any reported cyclophilin inhibitor known, by a wide margin...

Nash Phase 2 & 3 Trials by companies in the space:
AKRO Akero Therapeutics 1.1 Billion Marketcap 240 Million in cash
MDGL Madrigal Pharmaceutical 1.7 Billion Marketcap 300 Million in cash
HEPA Hepion Pharmaceuticals 160 Million market cap 120 million in cash

Currently trading at $2.2 due to a public offering of 44.000.000 shares $2

According to analysts' consensus price target of $80.00, Hepion Pharmaceuticals has a forecasted upside of 3,503.6% from its current price of $2.22.


Current Price
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HEPA News: Hepion Pharmaceuticals Announces Postponement of 2021 Annual Meeting of Stockholders 07/23/2021 04:40:00 PM
HEPA News: Current Report Filing (8-k) 07/13/2021 10:38:43 AM
HEPA News: Hepion shares fall after CRV431 mid-stage NASH study results 07/13/2021 08:32:27 AM
HEPA News: Hepion Pharmaceuticals Announces Positive Topline Data from Phase 2a ‘AMBITION’ NASH Trial; All Primary Endpoints Achieve... 07/13/2021 08:00:00 AM
HEPA News: Current Report Filing (8-k) 06/25/2021 04:47:31 PM
#1485  Sticky Note Page S321 Fress 06/24/21 06:06:41 AM
#1684   Retail has no power in this vote. chainweight 07/24/21 03:01:55 PM
#1683   Meeting postponed, what does this mean? Bourbon_on_my_cornflakes 07/23/21 10:43:00 PM
#1682   I am pretty sure that Fress is diamond StocktraderDK 07/23/21 05:55:46 PM
#1681   Lol jesus man he jumped the boat a CreampieMafia 07/23/21 05:25:12 PM
#1680   Hopefully you didn’t bail here. It’s been Ruffieruff 07/22/21 05:59:44 PM
#1679   Any pop will likely be small since the murocman 07/20/21 09:05:10 PM
#1678   The rest of the data from trials... Bertsllc 07/20/21 07:24:06 PM
#1677   What would be a catalyst for this to murocman 07/20/21 03:43:24 PM
#1676   This is crazy undervalued. Cash on hand 120M, Esa 07/17/21 01:44:45 PM
#1675   Yep, I’d say this is bottom;-) Bertsllc 07/16/21 12:42:02 PM
#1674   I'm Picking bottom... Bertsllc 07/15/21 08:15:34 PM
#1673   What will be the share count? Giovanni 07/15/21 07:27:48 PM
#1672   HEPA has about 7-8 of those qualifications. chainweight 07/15/21 03:39:55 PM
#1671   I obviously don't know enough about Hepion yet. Ambersavage7194 07/15/21 03:33:54 PM
#1670   Read this great article...... chainweight 07/15/21 10:16:49 AM
#1669   Welcome, lol Porterhouse10 07/15/21 09:56:49 AM
#1668   In for a few Planopenny 07/15/21 09:56:31 AM
#1667   I'm with you Giovanni 07/14/21 09:45:05 PM
#1666   GOOD CALL: Maybe 1.6 next Bourbon_on_my_cornflakes 07/14/21 06:34:41 PM
#1665   New to HEPA. Got in after hearing their Ambersavage7194 07/14/21 04:47:27 PM
#1664   Miss to hear from Fress need his positive vibes. StocktraderDK 07/14/21 04:35:55 PM
#1663   What a rollover. We’ve been steamrolled. Ruffieruff 07/14/21 03:44:29 PM
#1662   WTF are you talking about? It's never chainweight 07/14/21 02:38:49 PM
#1661   Tried to warn ya'll. I'm Ferda Homies not Ferda 07/14/21 12:41:38 PM
#1660   Maybe short this piggy to 1.53? Hell yea bro CreampieMafia 07/14/21 12:12:02 PM
#1659   Might find support at $1.55, if that breaks Porterhouse10 07/14/21 12:03:20 PM
#1658   Exactly CreampieMafia 07/14/21 11:59:42 AM
#1657   Where’s the bottom here. This is painful. They Ruffieruff 07/14/21 11:55:32 AM
#1656   Where's Fress now bball71 07/14/21 11:53:19 AM
#1655   Terrible red days , but I accumulated more shares. StocktraderDK 07/14/21 11:49:16 AM
#1654   Same $1.55-$1.68 Porterhouse10 07/14/21 08:47:15 AM
#1653   Im On the bid Planopenny 07/14/21 08:06:51 AM
#1652   Perfect ATM, no worries Porterhouse10 07/14/21 07:38:29 AM
#1651   Good DD from the best "Fress"... StocktraderDK 07/14/21 07:37:37 AM
#1650   Wait and see when $HEPA release news with StocktraderDK 07/14/21 07:32:15 AM
#1649   Its already has price targets above $4 and Ferda 07/14/21 07:24:31 AM
#1648   $HEPA I think we see some new price targets StocktraderDK 07/14/21 07:19:42 AM
#1647   Well I tried to warn everyone that would Ferda 07/14/21 07:08:19 AM
#1646   $HEPA from a poster @ ST Hepion will not StocktraderDK 07/14/21 06:21:57 AM
#1645   Explain to me what was so Terrible here. Ruffieruff 07/13/21 02:05:47 PM
#1644   Lol we hitting 1.6 today CreampieMafia 07/13/21 01:47:50 PM
#1643   I just added more shares in $HEPA. My avg. StocktraderDK 07/13/21 01:44:10 PM
#1642   All we need is midastouch, added twice today.. Esa 07/13/21 12:44:28 PM
#1641   Hepion shares fall after CRV431 mid-stage NASH study results midastouch017 07/13/21 12:28:51 PM
#1640   Following #56 Porterhouse10 07/13/21 11:22:08 AM
#1639   This is massive short covering. EDGX on chainweight 07/13/21 11:10:59 AM
#1638   Seeking Alpha is a giant POS! Porterhouse10 07/13/21 10:57:51 AM
#1637   Wow. Unlimited dumping. Where’s any retail buying. Looks Ruffieruff 07/13/21 10:50:00 AM
#1636   How convenient LOL pump much? CreampieMafia 07/13/21 10:20:36 AM
#1635   Nothing terrible that I read. This stinks but Ruffieruff 07/13/21 10:10:28 AM
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