***5/24/2017 NEWS UPDATE***
Great Basin Scientific Issued Second U.S. Patent for PCR Amplification Suppressor https://globenewswire.com/news-release/2017/05/24/995607/0/en/Great-Basin-Scientific-Issued-Second-U-S-Patent-for-PCR-Amplification-Suppressor.html
SALT LAKE CITY, May 24, 2017 (GLOBE NEWSWIRE) -- Great Basin Scientific, Inc.(OTCQB:GBSN), a molecular diagnostics company, today announced that the United States Patent and Trademark Office (USPTO) issued U.S. Patent 9,657,353 for the Company’s amplification suppressor. This patent is the second U.S. patent relating to Great Basin’s amplification suppressor technology, expanding the Company’s protection to assays, kits, and products. The protection afforded by this patent allows the Company to explore licensing of the technology to applications such as medical research, food safety, veterinary, and more.
“Environmental contamination by Staphylococcus species or any other bacteria environmental contaminant of clinical samples—producing false positive results—is a problem that has stymied the molecular diagnostics industry since its beginning, which was the impetus for our development of this technology,” said Robert D. Jenison, chief technology officer of Great Basin Scientific. “We believe our amplification suppressor is an important scientific advancement in its ability to fully suppress non-life-threatening environmental contaminants from a clinical sample. This important technology enables us to seek licensing opportunities with molecular diagnostics companies that operate outside of our market niche, and aligns with our growth strategy to broaden our revenue stream.” The technology, currently utilized in the Company’s Staph ID/R Blood Culture Panel, distinguishes between Staphylococcus species present in a clinical sample from a Staphylococcus contamination that is introduced during the sample collection or testing process. While not negatively impacting the appropriate clinical assay limit of detection, Great Basin’s technology completely blocks detection of contaminants present in the environment that may lead to a false positive result and potential misdiagnosis of a patient. A study, which was led by Jenison and published in the April issue of PLOS ONE, showed that the Company’s amplification suppressor completely blocked environmental contaminants in a clinical sample that were detected at rates as high as 40%. The full study can be accessed here. The new patent protects Staphylococcus-based products, including nasal swabs and pre-surgical screens, such as methicillin-resistant Staphylococcus aureus (MRSA) screens. Great Basin’s Staph ID/R Blood Culture Panel is the Company’s first commercial embodiment of the patented amplification suppressor technology. In addition to being used in its Staph ID/R Blood Culture Panel, the amplification suppressor technology is being utilized in the Company’s in-development SA Nasal Screen Test, and is expected to be used in future tests and panels. With this patent, Great Basin has eight U.S. patents issued, with 11 additional patents pending. Great Basin’s molecular diagnostics system offers low-, mid-plex and multiplex testing, with commercial assays available for the detection of Shiga Toxin-producing Escherichia coli (STEC), Group B Streptococcus (GBS), Toxigenic Clostridium difficile (C. diff), Bordetella pertussis, and a Staph ID/R Blood Culture Panel (SIDR) for identifying bloodstream infections caused by MRSA and other Staphylococcus species. Additionally, the Company is awaiting 510(k) clearance from the U.S. Food & Drug Administration (FDA) on a Stool Bacterial Pathogens Panel. Other tests in development include a direct-from-blood Candida Blood Infections Panel, a CT/NG/TV Test, and a Nasal S. aureus Pre-surgical Screen Test. ***4/12/2017 NEWS UPDATE*** Announced today (4/12/2017) that it has received CE Marking for its Stool Bacterial PathogensPanel. http://www.otcmarkets.com/stock/GBSND/news?id=155739