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https://clinicaltrials.gov/ct2/show/NCT05531786?cond=pacritinib&draw=2
Who knows if we will know some data before the closing of the deal?
now we can spend!
https://clinicaltrials.gov/ct2/show/NCT05552183?cond=pacritinib&draw=2&rank=2
https://clinicaltrials.gov/ct2/history/NCT05552183
https://clinicaltrials.gov/ct2/show/NCT05657613?cond=pacritinib&draw=2&rank=3
https://clinicaltrials.gov/ct2/history/NCT05657613
How sad all the difficulties encountered for JB's cunning!
After all, those who pay the most are the sick since time is the most precious thing we have!
Is it possible that there is no one willing to up the ante a bit?
Sobi's got a deal!
If it goes wrong they take 59 million!
It could happen
In the event of a termination of the Merger Agreement under certain specified circumstances, including (i) termination by CTI to enter into an agreement providing for a Superior Offer (provided that CTI did not materially breach its non-solicitation obligations in any manner that results in such Superior Offer), (ii) termination by Sobi following a Company Adverse Recommendation Change, (iii) termination by Sobi due to the CTI board of directors’ failure to include its recommendation in the Schedule 14D-9, (iv) termination by Sobi because CTI has materially breached its obligations in respect of the non-solicitation provisions in the Merger Agreement, or (v) termination by either CTI or Sobi if the closing of the transactions contemplated by the Merger Agreement has not occurred by the Outside Date or termination by Sobi prior to the Offer Acceptance Time if CTI breaches its representations, warranties or covenants in the Merger Agreement in a way that would cause certain conditions of the Offer not to be satisfied (subject to CTI’s right to cure the breach as set forth in the Merger Agreement prior to such time of termination), and (A) a bona fide “Acquisition Proposal” (as defined in the Merger Agreement) has been publicly disclosed after the date of the Merger Agreement and (B) within twelve months following such termination, CTI signs a definitive agreement for an Acquisition Proposal or consummates an Acquisition Proposal, in each case of the foregoing clauses (i)-(v), CTI is required to pay Sobi a termination fee equal to $59,000,000.
This summary is qualified in its entirety by reference to the Merger Agreement, which is filed as Exhibit 2.1 hereto and incorporated by reference herein.
BOOM!
MANY THANKS TO ADAM!
The price seems low to me, let's hope someone raises it!
Congratulations to all who are enjoying!
Hey HD did you buy any CTIC yet…..come Tuesday morning I’ll have 38k
Why did they bring it up early in the morning?
seems unusual to me!
FDA approval of VONJO (pacritinib) for the treatment of adults with intermediate or high-risk primary or secondary (post-polycythemia vera or post-essential thrombocythemia) myelofibrosis with a platelet count below 50 × 109/L.
$54 million in net sales in the first nine months following VONJO launch.
Over 1,000 patients commercially treated with VONJO in 2022.
Inclusion in the National Comprehensive Cancer Network® (NCCN®)
Oral presentation at the 64th American Society of Hematology (ASH) Annual Meeting and Exposition highlighted pacritinib as a potent activin A receptor type 1 (ACVR1) inhibitor with significant anemia benefit in patients with myelofibrosis. A receptor type 1 (ACVR1) inhibitor and anemia benefit. We look forward to continuing activities focused on market expansion in 2023, which are intended to drive quarter-over-quarter net sales increases
On February 7, 2023, VONJO was granted seven years of orphan-drug exclusive approval by the FDA for treatment of adults with intermediate or high-risk primary or secondary (post-polycythemia vera or post-essential thrombocythemia) myelofibrosis with a platelet count below 50 x109/L. The seven-year exclusive approval began on February 28, 2022.
https://investors.ctibiopharma.com/static-files/83278a88-ff8f-457a-bccf-1900fe5042d8
no sneak peeks on last quarter's sales
Upcoming Events
SVB Securities Global Biopharma Conference
Feb 15, 2023 at 3:40 PM EST
Guggenheim Partners 5th Annual Oncology Conference
Feb 8, 2023 at 10:45 AM EST
Well, won't he say anything about the year that just ended?
https://clinicaltrials.gov/ct2/show/NCT05657613?cond=pacritinib&draw=2&rank=3
Actual Study Start Date : January 3, 2023
Net VONJO sales of $32.9M since launch in March 2022*
tomorrow it's Adam Craig's turn with capsule therapy
https://investors.ctibiopharma.com/static-files/83278a88-ff8f-457a-bccf-1900fe5042d8
Stephen Oh, MD, PhD, Associate Professor of Medicine, Hematology Division at Washington University School of Medicine in St. Louis. "As anemia poses a substantial burden for patients with myelofibrosis, the potential role of pacritinib in addressing anemia is highly encouraging."
"As our understanding of the mechanism of action of pacritinib expands, the full potential of pacritinib as a therapy for cytopenic myelofibrosis is emerging," said Adam Craig, MD, PhD, President and Chief Executive Officer of CTI BioPharma. "We continue in our commitment to meaningfully change the treatment paradigm for cytopenic myelofibrosis."
https://wsw.com/webcast/jeff255/ctic/1835973
i like Adam Craig
who will buy today or tomorrow?
https://fintel.io/sst/us/ctic
180 milion share outstanding
17 milion short!
I see it for $ 10 because PAC is the best
and the FDA are taking notice
JB was right
JB was right
JB was right
JB was right
JB was right
JB was right
JB was right
Graig but why don't you propose to Pfizer to try PAC?
https://www.fiercepharma.com/pharma/europe-will-look-at-all-jak-inhibitors-following-safety-concerns-raised-trial-pfizer-s
owls are in no hurry!
https://www.youtube.com/shorts/yPm0Yqx2mcE
In the third quarter, CTI continued to make strong progress with the U.S. commercial laun ch of VONJO, delivering net revenue of $18.2 million, a 48% increase in sales compared to the second quarter.
IMO, careful cost management will lead to higher margins
made the due proportions...
INCY
Jakafi’s (a first-in-class JAK1/JAK2 inhibitor approved for polycythemiavera, myelofibrosis and refractory acute graft-versus-host disease) revenues came in at $619.5 million.
Jakafi® (ruxolitinib) net product revenues of $598 million in Q2’22 (+13% Y/Y) driven by volume growth; raising the bottom end of full year guidance to new range of $2.36 to $2.40 billion
https://www.targetedonc.com/view/reactions-to-the-latest-data-on-jak-inhibition-for-myelofibrosis
Who knows what the plans are? nothing in europe?
Could PAC be used in the remautological space given the problem of other inhibitors?
liquid shit but maybe it's better than thrombotic events
https://fintel.io/so/us/ctic
Institutional Shares (Long) 94,105,342 - 82.27%
Insider Ownership 13.84%
but someone….brrrrrr
https://fintel.io/sst/us/ctic
https://fintel.io/so/us/ctic
Institutional Shares (Long) 94,105,342 - 82.27%
Insider Ownership 13.84%
but someone….brrrrrr
https://fintel.io/sst/us/ctic
Jim Fong, the Company’s Chief Commercial Officer, has been promoted to Executive Vice President and Chief Commercial Officer, and will begin reporting directly to the Company’s Chief Executive Officer.
sounds good to me
Who knows why they promoted him?
Pacritinib is a JAK2/IRAK1/CSF1R/FLT3 inhibitor, with an established safety and efficacy profile in the treatment of myeloproliferative neoplasms (myelofibrosis) and of acute GVHD.
Pacritinib s immunomodulatory effects suggest therapeutic benefit for cGVHD, without abrogating the graft-versus-leukemia effect after HSCT.
Start - 20
https://clinicaltrials.gov/ct2/show/NCT04858256?cond=Pacritinib&draw=2&rank=1
it seems to be starting soon
https://clinicaltrials.gov/ct2/show/NCT02891603
what will they do?
pacritinib sales will be strong!
the drug is used after ruxolitinib...
Why is everything stopped? At least it seems
https://clinicaltrials.gov/ct2/show/NCT04858256?cond=pacritinib&draw=2&rank=1
So the second quarter is closed! We will have a more realistic sales projection!
I imagine Robocop busy presenting them, always interesting how he frames things!
For the rest it seems to me that everything has stopped!
So something comes to me
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06/03/2009 Cell Therapeutics Says Brown Uty. Study Reveals High Pathological Complete Response Rate for OPAXIO Treatment in Esophagus Cancer - Update http://www.rttnews.com/ArticleView.aspx?Id=968824&Category=Breaking%20News
http://ih.advfn.com/p.php?pid=nmona&cb=1244008008&article=38033450&symbol=N%5ECTIC http://www.tradingmarkets.com/.site/news/Stock%20News/2358071/
RAiDAR alerts Learn More About RAiDAR-LT |
company profile |
The Company focuses on the development, acquisition and commercialization of drugs for the treatment of cancer. ... MORE INFO CONTACT: Dr. James A. Bianco, M.D. (CEO) | Cell Therapeutics Inc 501 Elliott Avenue West Suite 400 Seattle, WA 98119 P: (206) 282-7100 P: (800) 215-CELL (US) F: (206) 284-6206 Company Home Page | Email |
Industry: Drugs SIC: 2834 Employees: 194 Locations: 4 State of Inc: WASHINGTON 1991 Development Stage? N | Transfer Agent: Computershare Investor Services Chicago, IL 60690 Investor Relations: Company | Authorized Shares: Unknown Source: 10-Q ( 06/30/2008 ) Outstanding Shares: 455,394,374 Source : April 30 , 2009 8K Fiscal Year End: December 31 |
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