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BriaCell Therapeutics Corp. (BCTX)

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Last Post: 6/29/2021 2:00:35 PM - Followers: 23 - Board type: Free - Posts Today: 0


About BriaCell

Dedicated to enhance the lives of cancer patients who are facing limited therapeutic options, BriaCell Therapeutics Corp. (OTCQB: BCTXF; TSX: BCT.V)’s mission has been to develop novel immunotherapies, as the most cutting edge technology to fight cancer. Immunotherapies have become the forefront of the cancer treatments because they use the body’s immune system to destroy the cancer cells, offering higher levels of safety and efficacy than chemotherapy, with less likeliness of recurrence.

Designed by our team of scientists and clinicians, BriaCell’s proprietary whole-cell based vaccine technology platform continues to show its impressive potential to establish a new model for treating cancer patients. Our lead product candidate, Bria-IMT™ (SV-BR-1-GM), is a genetically engineered whole-cell vaccine derived from a human breast cancer cell line. Bria-IMT™ is used in combination with multiple immune-modulators to powerfully trigger the immune system to recognize and eliminate cancerous cells.

In a preliminary Phase I clinical study in metastatic (i.e., Stage IV) breast cancer patients who had failed multiple treatments, Bria-IMT™ treatment significantly reduced the tumor size, without serious side effects. Importantly, the tumor regression was observed in other sites including the lung and even the brain -a difficult site. Impressively, the median lifespan of the patients was substantially longer than that of the comparable trials.

At our laboratory facility in Berkeley, CA, we are planning to expand our pipeline of oncology immunotherapy candidates using our proprietary technology platform.

Using the clinical data from the patients from the clinical studies, we are working to identify the molecular fingerprint of the patients for which the vaccine would be highly effective, and are planning to develop diagnostic testing products to identify this group. By directing the drug to the top-responders, we expect this approach to increase the likelihood of clinical trial success of Bria-IMT™ -to bring hope to thousands of cancer patients with few-to-no treatment options.

The company is currently recruiting its Phase I/IIa trial to further test Bria-IMT™ safety and activity in metastatic breast cancer patients. BriaCell maintains global rights for Bria-IMT™.

Phase I/IIa Clinical Study of Bria-IMT™ in Advanced Breast Cancer

BriaCell is currently recruiting patients to evaluate the safety and activity of Bria-IMT™ in an additional Phase I/IIa study in 25-40 metastatic breast cancer patients who have failed at least one course of treatment.

For the details of the trial, please visit For the details of the trial, please visit https://www.clinicaltrials.gov/ct2/show/NCT03066947

Roll-Over Combination Therapy Study

FDA has approved the roll-over combination study of Bria-IMT™ with pembrolizumab (Keytruda; manufactured by Merck & Co., Inc.) or ipilimumab (Yervoy; manufactured by Bristol-Myers Squibb Company) for patients previously treated with BriaVax™ from the ongoing Phase I/IIa Clinical Trial in Advanced Breast Cancer. The study is available for patents on the SV-BR-1-GM Phase I/IIa study who develop progressive disease. These patients will be eligible to roll-over into combination therapy with Keytruda or Yervoy, depending on the type of breast cancer they have.

More information on the roll-over combination study of Bria-IMT™ with either ipilimumab or pembrolizumab will be available on ClinicalTrials.gov (https://clinicaltrials.gov/ct2/show/NCT03328026)

KEYTRUDA® (pembrolizumab)

Manufactured by Merck & Co., Inc., KEYTRUDA® (pembrolizumab) is a prescription medicine that may treat certain cancers by working with the immune system. It has been approved for the treatment of a number of cancer indications excluding breast cancer.

For more information on pembrolizumab, please see:

About YERVOY® (ipilimumab)

Manufactured by Bristol-Myers Squibb Company, YERVOY® (ipilimumab) is a prescription medicine used in adults and children 12 years and older to treat melanoma (a kind of skin cancer) that has spread (metastatic) or cannot be removed by surgery (unresectable). It is a monoclonal antibody that works to activate the immune system and enabling them to recognize and destroy cancer cells.

For more informations on Ipilimumab, please see:


Clinical Development Timeline – Breast Cancer

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BCTX News: BriaCell Phase I/IIa Clinical Trial Combination Study in Advanced Breast Cancer Patients Open for Enrollment 07/14/2021 07:22:00 AM
BCTX News: BriaCell to Present at Three Upcoming Investor Conferences 07/12/2021 08:00:00 AM
BCTX News: BriaCell stock soars 10% after expanding breast cancer technology into multiple indications 06/16/2021 08:24:26 AM
BCTX News: BriaCell Therapeutics Expands Breast Cancer Platform Technology into Prostate, Melanoma, and Lung Cancers 06/16/2021 08:05:00 AM
BCTX News: BriaCell Therapeutics Announces Proceeds of US$12.88 Million from Warrant Exercises 06/10/2021 08:05:00 AM
#303   MarketsandMarkets 4th Annual Next Gen Immuno-Oncology Virtual Congress-US ThurstonHowell 06/29/21 02:00:35 PM
#302   https://www.globenewswire.com/en/news-release/2021/05/11/2226965/0/en/BriaCell-t ThurstonHowell 06/29/21 01:56:41 PM
#301   https://www.globenewswire.com/news-release/2021/06/16/2248189/0/en/BriaCell-Ther ThurstonHowell 06/16/21 03:04:27 PM
#300   https://finance.yahoo.com/news/briacell-reports-12-0-months-111200861.html ThurstonHowell 06/16/21 03:03:31 PM
#299   Terrible timing though. Absolutely killed any momentum. retireat40 06/03/21 08:31:22 PM
#298   Yeah that wasn't bad news with private offering HabibiFresh 06/03/21 11:47:24 AM
#297   Hopefully the squeeze alone will take it over jwakstock 06/03/21 11:23:34 AM
#296   Yes, Nasdaq halted it again, Those MMS timetomakemoney 06/03/21 10:56:42 AM
#295   My hunch the halt is because there are cbrad10480 06/03/21 10:52:23 AM
#294   What the Hell, there was a market for timetomakemoney 06/03/21 10:51:04 AM
#293   PPS could go either way... My hunch timetomakemoney 06/03/21 10:43:35 AM
#292   I've never seen a halt for news and cbrad10480 06/03/21 10:41:00 AM
#291   We thinking buyout with this halt? Wouldn't halt HabibiFresh 06/03/21 10:38:51 AM
#290   Yeah real curious was about to happen HabibiFresh 06/03/21 10:37:46 AM
#289   100% resolution for eye-bulging tumors I love it HabibiFresh 06/03/21 10:37:28 AM
#288   Over an hour and BCTX is still halted. timetomakemoney 06/03/21 10:35:37 AM
#287   Yall seen a halt before big news before? HabibiFresh 06/03/21 10:19:34 AM
#286   Has to be more than that as it's Penny chatter 06/03/21 10:11:18 AM
#285   Offering news out...$5.26 with exercise at $6.17 it appears. retireat40 06/03/21 09:46:39 AM
#284   News Out! Public offering 5.2 million shares and warrants. timetomakemoney 06/03/21 09:43:37 AM
#283   Company: BriaCell Therapeutics Corp. ANTADOG 06/03/21 09:17:47 AM
#282   Look again INFINITI 06/03/21 09:15:33 AM
#281   Bid now 10 dollar, what i see, ANT ANTADOG 06/03/21 09:14:47 AM
#280   Yes. Windsortrader519 06/03/21 08:56:13 AM
#279   correction bid is now 8,50, fyi ANT ANTADOG 06/03/21 08:44:39 AM
#278   i hope this one gets attention from the ANTADOG 06/03/21 08:43:45 AM
#277   There is no bid or ask INFINITI 06/03/21 08:41:08 AM
#276   you mean why it stays 6,50 pm with ANTADOG 06/03/21 08:19:45 AM
#275   Did they halt this INFINITI 06/03/21 08:11:34 AM
#273   massive day here 146 million volume and counting Nebuchadnezzar 06/02/21 06:42:13 PM
#272   * * $BCTX Video Chart 06-02-2021 * * ClayTrader 06/02/21 04:47:49 PM
#271   Raised 27M - Market Cap 42M - with aristotelisonassis 06/02/21 04:43:54 PM
#270   Nope...shorts are killing this. retireat40 06/02/21 04:02:36 PM
#269   Great call...lol retireat40 06/02/21 04:01:59 PM
#268   something smells fish here. where is the big aristotelisonassis 06/02/21 03:15:00 PM
#267   Wow!! 134million Volume with a 7million Float. Yet cbrad10480 06/02/21 02:16:24 PM
#266   Thanks. iidris 06/02/21 01:44:49 PM
#265   $7 break lets go! MonstaGains 06/02/21 01:31:17 PM
#264   Im seeing a late day run and close MonstaGains 06/02/21 01:05:07 PM
#263   Done until after hours... retireat40 06/02/21 12:27:37 PM
#262   May go sub $7 here...shorts running the show. retireat40 06/02/21 11:44:10 AM
#261   Today was fun. Thanks for the ride blackpilled 06/02/21 11:26:40 AM
#260   Market cap only $50M right now. Should be MonstaGains 06/02/21 11:21:42 AM
#259   100 mil volume INFINITI 06/02/21 11:20:54 AM
#258   Only matter of time until it breaks $9.00 MonstaGains 06/02/21 11:20:41 AM
#257   100 mil come insane $$$ INFINITI 06/02/21 11:20:39 AM
#256   Cmon push $$& INFINITI 06/02/21 11:18:49 AM
#255   I know damn sellers let’s push it hard INFINITI 06/02/21 11:17:54 AM
#254   Etrade extended hours trading and it's commission free king koopa 06/02/21 11:12:36 AM
#253   its in new price discovery process. hard to Nebuchadnezzar 06/02/21 11:09:40 AM
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