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AstraZeneca PLC (AZN)

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Last Post: 1/22/2018 12:08:39 PM - Followers: 14 - Board type: Free - Posts Today: 0

AstraZeneca PLC discovers, develops, manufactures, and markets prescription pharmaceuticals in the areas of cardiovascular, gastrointestinal, neuroscience, oncology, respiratory and inflammation, and infection worldwide. Its products include Arimidex for hormonal breast cancer; Crestor that provides treatment for managing cholesterol levels; Nexium for acid-related diseases; Seroquel, an atypical anti-psychotic therapy for treating schizophrenia and bipolar mania; and Symbicort for the maintenance treatment of asthma in patients. The company also engages in the research, development, manufacture, and marketing of medical devices and implants for use in urology, surgery, and odontology. In addition, it develops and manages out-patient cancer centers in the United States. AstraZeneca markets its products to primary care and specialist physicians, as well as to other healthcare professionals, governments, and healthcare buying groups through sales and marketing network, local marketing companies, distributors, or local representative offices. It has strategic alliances with AtheroGenics, Inc.; Pozen, Inc.; Bristol-Myers Squibb Company; Cambridge Antibody Technology Group plc; KuDOS Pharmaceuticals Limited; WuXi Pharmatech Co., Ltd; and ChemBridge; and a strategic partnership with Peking University Third Hospital. The company also has collaborations with Palatin Technologies, Inc.; Schering AG; Protherics PLC; Targacept, Inc.; Abgenix; Dyax Corp.; Abbott Laboratories; BioFocus DPI; Silence Therapeutics plc; Argenta Discovery Limited; Effector Cell Institute; Cancer Research Technology Limited; Beatson Institute for Cancer Research; and Myriad Genetics, Inc. It has an agreement with Biovator AB to co-operate on the development of an in vitro-test that identifies potential allergens. AstraZeneca was founded in 1992. It was formerly known as Zeneca Group PLC and changed its name to AstraZeneca PLC in 1999. The company is headquartered in London, the United Kingdom. AstraZeneca Shrugs Off Pipeline Concerns Tuesday November 20, 2:30 pm ET By Jennifer Sterling, AP Business Writer AstraZeneca R&D Head Asserts That Beefed-Up Pipeline Will Offset Wall Street's Growth Fears AstraZeneca is one of several branded pharmaceutical companies struggling to fend off competition from cheaper, generic drugs. The stock, which hit a new year-low of $43.76 on Tuesday, is down nearly 16 percent for the year. But Patterson insists the company's improved research and development strategy will offset the effect of generics, and points to vaccine and biotech drug candidates acquired in AstraZeneca's June takeover of MedImmune Inc. However, for the most part, analysts say their main concern is the declining performance of the company's top-selling drugs. Credit Suisse on Tuesday lowered its price target on AstraZeneca shares to 23.75 pounds ($48.74) from 26.25 pounds ($53.87), due in part to a recent patent challenge facing Crestor as well as slowing growth in the U.K. Bear Stearns analyst Alexandra Hauber said in a recent note to investors that Crestor's market share has been flat in the slowing cholesterol market. "The key issue in coming weeks is whether Crestor's prescriptions can accelerate on the back of the new atherosclerosis label," she said. Earlier this month, the FDA approved Crestor for a new use against an artery disease that can lead to heart attack and stroke. In addition to generic competition, AstraZeneca has faced the loss of late-stage drug candidates in recent years. Most recently, its compound ZD4054 for prostate cancer failed a midstage study. The Phase III drug setbacks, in particular, compelled AstraZeneca to create an R&D strategy focused on speed, Patterson said. "We realized our pipeline just wasn't good enough," he said. "We had to turn things around." An internal speed initiative was launched in October to push medicines through development faster, by setting time targets for each phase of development, Patterson added. Among other new priorities, the drugmaker has placed biologics, diabetes, cancer and vaccine treatment candidates at the forefront. AstraZeneca has also sought to maximize uses for blockbuster products like Crestor and anti-psychotic Seroquel, which also recently received expanded approval from the Food and Drug Administration. And like other branded drugmakers, AstraZeneca has beefed up its pipeline through acquisitions. Helped by the purchase of nasal spray flu vaccine maker MedImmune, the company now has eight new drugs in late-stage development, double the number at the start of 2007. The MedImmune deal instantly boosted AstraZeneca's proportion of biotechnology drugs in development to 27 percent from just 7 percent, and gave it entry to the coveted vaccine space. However, the deal only added one late-stage drug candidate to AstraZeneca's pipeline -- motavizumab, a humanized monoclonal antibody designed to prevent serious lower respiratory tract disease. Patterson, nonetheless, brushes off criticism from analysts who have called the pipeline thin. "I believe we're going to prove analysts wrong. They're entitled to their opinion of our pipeline, but it's hard to say AstraZeneca's pipeline is empty," he said. "No doubt about it, we will be bringing a stream of medicines to market that will be valuable and differentiated, and good for patients and AstraZeneca." ___________________________________________________________________________________________________________________ ADDITIONAL INFORMATION AND HELPFUL WEBSITES Support & Resistance Levels---> Drawing Trendlines---> "Areas" to Take Profit---> High Probability Trade Set Up---> 5 Day Rule---> Positive Divergences---> Trendline Break + 50% Hold---> "The Pincher"---> Da Tarheel Method by Tarheel-Blue ---> Lesson in Buying by Tarheel-Blue --->
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AZN News: LYNPARZA® (olaparib) Approved by US FDA in Germline BRCA-Mutated Metastatic Breast Cancer 01/12/2018 12:45:00 PM
AZN News: US FDA Updates SYMBICORT Label with LABA Safety Class Revisions and Removes Boxed WARNING for Serious Asthma-Related Outcomes 12/21/2017 11:15:00 AM
AZN News: US FDA Accepts Regulatory Submission for TAGRISSO (Osimertinib) in 1st-Line EGFR-Mutated Non-Small Cell Lung Cancer 12/18/2017 07:00:00 AM
AZN News: AstraZeneca’s CALQUENCE® (acalabrutinib) Shows Potential in Chronic Lymphocytic Leukemia Trials 12/10/2017 05:45:00 PM
AZN News: AstraZeneca’s CALQUENCE® (acalabrutinib) Demonstrates Activity in Relapsed or Refractory Mantle Cell Lymphoma Trial 12/09/2017 01:00:00 PM
#118   AZN is a Company with more in the Equitiesduke 01/22/18 12:08:39 PM
#117   Sounds like AstraZeneca will certainly require a license biopharm 12/02/17 07:07:36 AM
#116   Glad you found that useful.....there is now further, north40000 12/01/17 05:50:39 PM
#115   North40K- This is an older post of yours biotech_researcher 12/01/17 04:18:25 PM
#114   AstraZeneca PLC, (NYSE:AZN)-Technical Analysis HERMES8 09/30/17 09:42:22 AM
#113 Avispa 08/28/17 07:59:02 AM
#112 Inoviorulez 08/18/17 08:17:13 PM
#111   AZN 2Q17 CC slides: DewDiligence 08/12/17 05:40:15 PM
#110   NO MORE PRICKS - Quick Dissolvable Tablets is corpus 08/10/17 04:48:41 PM
#109 Inoviorulez 08/02/17 05:11:19 PM
#108   Imfinzi: 2 BTDs now in place from FDA--- north40000 07/31/17 07:58:07 AM
#107   Cheaper for PFE takeover. willlbone 07/27/17 11:59:29 AM
#106 Inoviorulez 07/27/17 10:39:39 AM
#105   AZN - Got out at $35. SevenTenEleven 07/27/17 09:53:04 AM
#104   AZN - This appears to be a coordinated SevenTenEleven 07/14/17 06:14:36 PM
#103   Doesn't seem to be having an effect on JWard99 07/14/17 05:23:45 AM
#102   AZN - Will be selling my position in SevenTenEleven 06/17/17 02:35:35 PM
#101   AZN: Below appears to be a well-done, recently north40000 06/17/17 12:23:12 AM
#100 north40000 05/12/17 10:05:04 AM
#99   AstraZeneca Head of Neuroscience, Dr Iain Chessell, presents TERIA 04/11/17 11:15:10 AM
#98   Several AZN-based tweets from attendees at the SGO north40000 03/17/17 01:03:46 AM
#97   Sanofi working on intra-nasal Fluzone to compete with Trend-Setter 03/02/17 08:06:18 PM
#96   $AZN $28.37 ClearlyStocks 11/11/16 12:33:51 PM
#95   $AZN 28.09 ClearlyStocks 11/11/16 11:50:10 AM
#94   $AZN $27.70 ClearlyStocks 11/11/16 11:48:25 AM
#93   AstraZeneca spinoff starts trading as ALBO 11/4/2016 djpope 11/03/16 12:18:58 PM
#92 north40000 10/05/16 03:25:18 AM
#91   Who blacked out portions of this link? Why north40000 09/29/16 04:01:16 AM
#90   AZN:: Then there is this PPHM conference call north40000 09/28/16 03:43:38 PM
#89   AZN: There must be a reason behind this north40000 09/28/16 02:55:18 PM
#87   FDA To Decide On AstraZeneca ZS-9 venturecapp 05/16/16 12:49:30 PM
#86   Test rc990 04/25/16 07:36:42 PM
#85   AZN buys ZS Pharma...2.7 billion $$$. Cardiovascular sector north40000 11/06/15 06:55:12 AM
#84   Meantime,nearly 2 years later, perhaps AZN will find north40000 03/24/15 06:50:17 PM
#83   Awesome relative strength in AstraZeneca. I think that Stock Trading Guru 01/29/15 11:15:40 AM
#82   AstraZeneca says Pegasus-TIMI 54 study met primary efficacy endpoint jimmybob 01/14/15 07:06:57 AM
#81   AstraZeneca ovarian cancer drug wins European green light Penny Roger$ 10/24/14 11:17:22 AM
#80   WISH you would have twisted my arm not ernie44 05/19/14 10:24:14 AM
#79   Monday’s pre-market earnings report was not a strong EZ Trader 05/05/14 05:45:16 PM
#78   AZN rejects PFE’s sweetened offer: #msg-101495787. DewDiligence 05/03/14 01:22:22 PM
#77   PFE sweetens offer for AZN to nominal value DewDiligence 05/02/14 07:12:32 PM
#76   PFE RAISING ITS STAKE TO BUY AZN WatchTV 05/01/14 12:25:06 PM
#75   AZN rejects PFE—at least for the time being: #msg-101233685. DewDiligence 04/28/14 06:45:53 PM
#74   Looks like- it is not over yet!! Speculators free_bee 04/28/14 07:44:36 AM
#73   PFE's $101B offer was rejected, according to the DewDiligence 04/25/14 03:50:12 PM
#72   I think they have an offer of $100 free_bee 04/21/14 02:57:56 PM
#71   As some of AZN drugs are maturing and Bngo 04/21/14 03:30:02 AM
#70   AstraZeneca has been particularly aggressive recently as it Scorpion King 06/09/13 10:19:16 AM
#69   AZN settles Crestor US patent case: #msg-86062636. DewDiligence 03/25/13 08:32:25 AM
#68   Article on AZN’s surprising deal with Moderna: #msg-85963357. DewDiligence 03/21/13 04:38:41 PM