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Algernon Pharmaceuticals Inc. (AGNPF)

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Last Post: 3/31/2020 1:05:55 PM - Followers: 116 - Board type: Free - Posts Today: 5

Algernon Pharmaceuticals is a clinical stage drug development company focused on the areas of non–alcoholic steatohepatitis (NASH), chronic kidney disease (CKD), inflammatory bowel disease (IBD) and idiopathic pulmonary fibrosis (IPF).

 
The Algernon drug development program was the brainchild of Dr. Mark Williams, the Company’s CSO, whose innovative approach to drug discovery was developed over many years as senior scientist in the drug development industry. The company and its business model is highly capital efficient and strives to deliver maximum shareholder value.
 
Algernon’s unique approach to drug discovery is based on the concept of drug repurposing. Drug repurposing is the process of discovering new therapeutic uses for existing drugs. Repurposing offers several benefits over traditional drug development including a reduction in investment and risk, shorter research periods and a longer active patent life.


Drug Repurposing Strategy

A Drug Repurposing Strategy Can Save up to 8 years of Pre-Clinical Research And Multi Millions in R&D Costs.

 The Algernon business model is to take safe approved genericized drugs, screen them in globally accepted animal models for new diseases, file new intellectual property rights and then efficiently move them into off label phase II trials in the country where they were originally approved. Once a signal is established in a human trial, the company will begin to advance the repurposed drug through a US FDA registration.

11 drug candidates were initially screened by the Company in globally accepted in vivo animal models for 4 new disease areas:

Non-alcoholic Steatohepatitis (NASH)
Chronic Kidney Disease (“CKD”)
Inflammatory Bowel Disease (IBD)
Idiopathic Pulmonary Fibrosis(IPF)

Initial studies showed that a number of the 11 drug candidates either performed equal to or better than the positive controls in each of the animal studies. Subsequent in vivo studies have confirmed their efficacy.

All Algernon research studies were conducted by 3rd party contract research organizations. The studies were well designed with proper positive controls, using the currently accepted gold standard for treatment in the disease being screened.



Targeted Diseases

Algernon Pharmaceuticals has developed strong pre-clinical data that supports the advancement of 4 of its leading drug candidates into phase II trials in the areas of non–alcoholic steatohepatitis (NASH), chronic kidney disease (CKD), inflammatory bowel disease (IBD) and idiopathic pulmonary fibrosis (IPF).
 
Non–alcoholic Steatohepatitis

 

CKD

Chronic Kidney Disease

 

IBD

Inflammatory Bowel Disease

 

IPF

Idiopathic Pulmonary Fibrosis

 
 

Christopher J. Moreau, Chief Executive Officer
Mark Williams PhD MBA, Chief Science Officer

General Inquiriesinfo@algernonpharmaceuticals.com
Head Office: Suite 915 – 700 West Pender Street Vancouver, BC, Canada V6C 1G
Shares Outstanding: 90.0M    Fully Diluted: 141.6M


  
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#7018  Sticky Note Algernon Submits for Ethics Approval for Phase 2 shell3 03/30/20 08:41:50 AM
#6356  Sticky Note Algernon Announces Coronavirus Update Featured on BioPub Hosted AMG 03/10/20 08:59:13 AM
#7049   The CEO told us there are experienced biotech AMG 03/31/20 01:05:55 PM
#7048   .hey guys......lunch break....just checking in for any new jaggerxj6 03/31/20 12:22:56 PM
#7046   As my past post says, 'We need to tcm7 03/31/20 10:28:19 AM
#7045   Should I buy now? jbnavy 03/31/20 10:11:06 AM
#7044   The day will come for Pennyland Flip Floppers AMG 03/30/20 10:17:20 PM
#7043   Australian goverment...$$$$ https://www.health.gov.au/ministers/the-hon-greg-hunt-mp/media/fast-tra smoki 03/30/20 08:25:44 PM
#7042   https://www.linear.org.au/sponsors/sponsor-faqs/ Australia Ethic’s + smoki 03/30/20 08:18:42 PM
#7041   Nice find Smoki - at 0:53 seconds the DannyDanboy 03/30/20 08:12:43 PM
#7040   Onto much greener pastures. As we inch closer DannyDanboy 03/30/20 08:03:34 PM
#7039   https://m.youtube.com/watch?v=5bGsnyVMWso Australia lab’s + smoki 03/30/20 08:01:41 PM
#7038   Naw...I got the point. AMG 03/30/20 02:29:16 PM
#7037   Made some sense that someone's breath would be tcm7 03/30/20 02:20:49 PM
#7036   Without data, but with Trump praise, FDA issues AMG 03/30/20 02:18:23 PM
#7035   AGN 436,939 Volume & $AGNPF 408,192 Volume shell3 03/30/20 02:12:14 PM
#7033   ....it has already.....you are in the midst of jaggerxj6 03/30/20 12:25:33 PM
#7032   When is blast off jbnavy 03/30/20 12:19:19 PM
#7031   .PS>>>my allocation advice is a holding of no jaggerxj6 03/30/20 12:02:13 PM
#7030   hey guys.....just checkin "IN" for my daily review jaggerxj6 03/30/20 11:41:00 AM
#7029   I follow the facts. Management is not the AMG 03/30/20 11:06:33 AM
#7028   Yeah I know — Some don’t want to shell3 03/30/20 11:02:36 AM
#7027   Seriously...now after ALL we know in black and white? AMG 03/30/20 10:48:25 AM
#7026   Give Us the “Sleeper Press Release shell3 03/30/20 10:37:50 AM
#7025   President just predicted 200k lives will be Coronaized rodman 03/30/20 10:34:41 AM
#7024   Gonna see this have a stamp !! shell3 03/30/20 10:06:56 AM
#7023   TRIAL REGISTRATION!!! medchem 03/30/20 09:49:31 AM
#7022   Furthermore, for those interested in the science: medchem 03/30/20 09:48:24 AM
#7021   Holy crap their on fire. medchem 03/30/20 09:45:56 AM
#7020   Engine’s ignited!!!!!$$$$$ smoki 03/30/20 08:52:07 AM
#7019   $AGNPF shell3 03/30/20 08:42:18 AM
#7018   Algernon Submits for Ethics Approval for Phase 2 shell3 03/30/20 08:41:50 AM
#7017   $AGNPF shell3 03/30/20 08:41:44 AM
#7016   COVID-19 Drug Research Roundup shell3 03/30/20 08:19:49 AM
#7015   Ifenprodil works on the NMDA receptor on neurons. medchem 03/30/20 08:09:21 AM
#7014   https://www.centerwatch.com/articles/24603-covid-19-update smoki 03/30/20 08:08:54 AM
#7013   My thoughts: medchem 03/30/20 08:03:24 AM
#7012   Killer Science @ Algernon Pharmaceuticals AMG 03/30/20 03:00:03 AM
#7011   FDA got Algernon’s back ... MAR’s Diamond in smoki 03/30/20 01:34:14 AM
#7009   3-D image . https://amp.cnn.com/cnn/2020/03/26/health/covid-19-lung-damage-video/index.html smoki 03/29/20 12:28:41 PM
#7008   Lung damage Corona Virus https://www.google.com/amp/s/www.businessinsider.com/coronavirus-survivor smoki 03/29/20 12:12:04 PM
#7007   IHUB Info for Traders Trading Traders shell3 03/29/20 12:10:53 PM
#7006   Your timeline is reasonable. See point 3 below medchem 03/29/20 10:51:32 AM
#7005   Algernon might want to tap Mark Zuckerberg $$$ https://www.google.com/amp/s/www. smoki 03/29/20 10:29:16 AM
#7004   Just a Reminder [/http://www.globenewswire.com/fr/news-release/2019/12/05/195 smoki 03/29/20 01:36:51 AM
#7003   They Don't Know ~ Who We Be AMG 03/29/20 12:44:51 AM
#7002   Pure Science @ Algernon Pharmaceuticals AMG 03/28/20 11:03:23 PM
#7000   CONGRATULATIONS TO AGNPF MESSAGE BOARD AMG 03/28/20 01:49:01 PM
#6999   Any new’s and we Fly could be today, smoki 03/28/20 01:23:07 PM
#6998   I did paint a broad stroke over the AMG 03/28/20 01:00:45 PM
#6997   your time line is way off.... won’t have smoki 03/28/20 01:02:23 AM
#6996   https://milkeninstitute.org/sites/default/files/2020-03/Covid19-Tracker-3-36-20-FINAL.pdf One week smoki 03/27/20 08:57:02 PM
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