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Diabetes - WEB Publication Forum
For Patients, Health Professionals, Interested Persons and Investors
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World Diabetes Health Care Org.
Charity Non-Profit Organization
For The Best of Humans Worldwide
To help Diabetes People worldwide to get The Information they need by One View
or One Source to better understand and manage it to have a happy Diabetes Life.
Our aim is also to create The Awareness For The Ongoing World Epidemic for the
Political Parties, Governments and Institutions to do what it need to improve the life
of Diabetic People and to avoid abuses of such as by Health Insurances or at Jobs
or Careers, Etc. or getting treated as 2nd Class People and instead to receive the
preference status by humanistic civilized ways to release some of the burden,
problems and difficulties in their daily life.
As world first and only we publish the Detailed Practical Therapies Approach by information’s
as usually only by Doctors in Diabetology - Endocrinology provided if they have enough time,
for the Diabetic People able By Self- Management to improve the HbA1c or A1C Values, Etc.
and To Reduce Any Risks for Associated Diseases such as Neuropathies, Retinopathies,
Cardiovascular-, Micro- Macro- Vascular- Disorders, Etc. Up-To Amputations To Avoid.
Our Email Contact: WDHCO@outlook.com
( We Don’t Sell Anything and Act without Sponsors to remain Neutral. We will also never cooperate with
any Telemarketing Firms to get only 20% of the Donated Money as the ADA does. Resulting of what we
receive to 98% gets into informative WEB Diabetes Care Publishing. Our Members work on Goodwill base. )
This is the World Only WEB-Site with Medical Advices to help Patients and Doctors !
A Summary ( As more successful we get, as more we get sabotaged by the help of Google. )
That’s Why At WEB Cannot See Us Everyday - LoL ! Where Not Everybody Appreciates Our Truths By Speak-Outs.
We also internationally in contact with the WHO, UNESCO, Europe EMA-EMC, NIH.Gov, IDF to get healthier
better Guidances & Diagnostic Standards & Therapies for Diabetics able to fight the Ongoing Epidemic !
By Our Honest Truth just Openly- Speak- Out we also provoke others as seen to
get More Active and They Also Copy- Apply Our Info instead of Sleeping as during
the past 20 Years which resulted to the Worldwide Diabetes Epidemic !
Like this we also very happy to provoke- forcing others as the ADA & CO to be
More of Help and More Objectively for In Favor of All Diabetics Worldwide.
We Not The Convenient Once, But The Only Once Providing The Full Pictures With Solutions !
At Forums or Communities or Magazines or Associations as seen, the Diabetic People cannot
even find anything of How to Improve the A1C, Etc., but find reiterated Poor Guidance- Norms
and Attractions for selling Products or Puzzles ( LoL ) or Confusions by some News as daily
updated declared to attract.
( For example the Diabetes.co.uk is a good example of Fake Fooling just creating attractions to sell its Products. Where its Forum Members get hypocrite motivated to provide
any Diabetic Advice or Support possible and when this naturally medically by best experiences made, the Posts as medically get Deleted and the Forum Members Get Banned !
Diabetes.co.uk declares themselves world’s leading support community for people with diabetes. Presently just too many like to do business with Diabetes.
Other WEB- Sites or Forums Have The Hypocrite Policy At Medical Topics Any Medical Advices Not Permitted. Resulting What For Such Sites ? )
For Diabetics it’s frustrating to see how much is published in the Internet or what is ongoing
and how little if any is really helpful and that’s where We Show The Difference Just To Help !!
We Change and Improve now of what the ADA and Followers during the last
20 Years failed to do by the Diabetes Epidemic Resulting. Just creating some
Press Releases at weekly base or So-Called Studies do not compensate this.
All Associations or Organizations in the Diabetes Field financially successfully,
as Greedy-Slaves need to please the international Health Insurances- and the
Pharmaceutical- Industries and by this losing the objectivity and reference by
the resulting conflicts of interests !
Something we will never do. We accept only free unconditional-money from
the Hearts to support the Diabetes Matters, nothing else !!
Charitable we do this worldwide By Diabetes Related Keywords for by Google Search
to see at any FrontPages to get the maximum of Clicks and Interests as necessary.
This is costly and therefore we would really appreciate any Donations to do it as
good as necessary.
For this Please Donate to our Bank-Account: Swissquote Bank SA, IBAN Code: CH8108781000070145100
with Beneficiary / Comment: WDHCO
If this is not been seen At Every FrontPages as necessary by just using one Keyword
as for example "Diabetes", it would mean only that we regrettably did not receive
enough Companies- or Private- Donations for doing this.
The WDHCO Donation-Status Not Yet Sufficiently.
( WDHCO in June 2017 also with some Diabetics established at lowest costs as seen here. We are
planning to do a nice WEB-Page with a WEB-Designer when we have the money for and doing place-
reservations for the Pages 1 it need to create the necessary awareness. This would need to be done
by Advertisement at Google AdWords for the Medical Field with $ 1.49 Costs Per Click.
This only for all to know !
All companies seen more at front, for a Preferred Status monthly pay to Google $ 4,000 - 8,000
to be seen on the WEB. It's not just Clicks- Based and they call that helping. Google as known
also applying some abusive tricks. )
If You A Diabetic and Really Care About Improvements of the Diabetics Situations, then you should
Take That Chance Here To Get The Words Out And Donate even any small amount You Can Afford,
because by the experiences The Non-Diabetics Usually Don’t Care About As Long They Not Became
Diabetics Themselves and just concentrate on any other interests in days life.
Diabetics Need Anything, but maybe not so willing In-Return to provide Anything.
According of WHO-World Health Organization we have now about 1.5 Billion
of Diabetes affected People and this by increasing tendency as confirmed !
Always November 14th Is The World Diabetes Day To Remember.
This Site Will Be Continuously Further Completed And Updated To Aware.
ADA – American Diabetes Association 2018 Standards
http://diabetesed.net/wp-content/uploads/2017/12/2018-ADA-Standards-of-Care.pdf
General Topics http://care.diabetesjournals.org/content/41/Supplement_1
Instead considering this Useless US ADA and NIDDK, Etc., Money-Followers, it’s much
better to consider here the Topic “Objective Diabetes Standards & Guidelines” !
European - ESC & EASD Guidelines on Diabetes, Pre-Diabetes, and Cardiovascular Diseases.
The Task Force on diabetes, pre-diabetes, and cardiovascular diseases of
the European Society of Cardiology (ESC) and developed in collaboration
with the European Association for the Study of Diabetes (EASD).
Have a good look to its Report Topic 4.x.x. !
The ESC & EASD Study Report Here http://journals.sagepub.com/doi/10.1177/1479164114525548
Roche Diabetes Care – CGM & Insulin Pump Systems
https://www.roche.de/en/diagnostics/diabetes-care-vision.html
https://www.accu-chek.com/
Novartis - Google Diabetes Care
http://medicalfuturist.com/googles-amazing-digital-contact-lens-can-transform-diabetes-care/
https://www.pharma.us.novartis.com/our-products
Abbott Diabetes Care - CGM System
https://www.diabetescare.abbott/index.html https://www.diabetescare.abbott/products.html
Pfizer - Diabetes & Metabolic Disorders
http://www.pfizer.com/health-wellness/diseases-conditions/diabetes-metabolic
Merck Diabetes Care
http://www.merck.com/about/featured-stories/diabetes_care.html
Dexcom - CGM Glucose Monitoring
https://www.dexcom.com/contact
Metronic - CGM & Insulin Pumps Systems
https://www.medtronicdiabetes.com/home
Glooko - New FDA Approved Diabetes Management System
https://www.glooko.com/
Dual Insulin & Glucagon Pump Systems – Artificial Pancreas – Near Diabetes Future
https://www.nih.gov/news-events/news-releases/four-pivotal-nih-funded-artificial-pancreas-research-efforts-begin
https://diatribe.org/introducing-beta-bionics-bringing-ilet-bionic-pancreas-market
The logically or physical reality here reconfirmed about Sensor- Controlled- Insulin- Pumps,
where anything else related to Insulin- Pumps should have been prohibited as from the
beginning. When Control is important, then Sensors to control it naturally needs !
https://www.news-medical.net/news/20181003/Closed-loop-insulin-delivery-system-shows-better-results-for-blood-sugar-control-in-type-1-diabetes.aspx
Index Table of Topics
- Introduction, Associations and Companies in the Diabetes Field.
- Dual Insulin & Glucagon Pump Systems - Artificial Pancreas – Near Diabetes Future.
- Objective Diabetes Standards & Guidelines
- If You Have A Question or Problem Until Now Without Solution ?
- 1. Diabetes-Related Microvascular and Macrovascular Diseases.
- 2. HbA1c or A1C Values & Target Value.
- 3. Diagnostic Standards.
- 4. Diabetes Awareness & Precautions.
- 5. The Simple Therapy Rules For At Any Diabetes Types To Apply.
- 6. Swollen Feet’s & Higher Blood Pressure & Neuropathies Checking.
- 7. When You Get A New Insulin-Pen To Use.
- 8. Calibrations at CGM-Continuous Glucose Monitoring Systems.
- 9. Important Information’s For Basal-Insulin Users And Patients.
- 10. Injection Technique / Basal-Insulin.
- 10.A) At Rapid-Insulin Applications.
- 10.B) Hypoglycemia - Hypos - Low Sugar - Cramps.
- 10.C) Hyperglycemia - Hypers.
- 10.D) Glucose Measuring - Lost Insulin Effect.
- 11. New Anti-Hypogenic Combination Therapy by Metformin, Glucobay, Januvia for T2D + T1D.
- 12. How to set the Basal-Insulin Dose as very important for the Necessary Base Effect.
- 13. About Glucose mg/dl.
- 14. About Diabetes Therapies In General.
- 15. Beta-Cells Transplants or Beta-Cells-Therapies or Immune Therapies To Cure Type 1 ?
- 16. Doctors Symptoms List.
- 17. Healthy Nutrition Opportunity & Supplements. ( Also about important Potassium, Aspirin, Etc. ! )
- 18. Drinking Alcohol and Diabetes.
- 19. Diabetics Erection Disorders.
- 20. Misdiagnosed Diabetes Type 3c.
- 21. Gene Mutation Causes MODY Diabetes.
- 22. UKs Top 10 Priorities For Type 2.
- 23. Smart Synthetic Beta-Cells Insulin T1D & T2D Patches Treatments ?
- 24. The Brain Also Produces Insulin.
- 25. Over Weight Problems & Type 2.
- 26. Nov. 2017 Study Report - ADA Diabetics Fooling Masterpiece ?
- 27. Nov. 30th - How Naïve To Reach Out To NIDDK !
- 28. The ACCORD Study 2009 Should Never Been Made By Its Incomplete Conclusions !
- 29. Diabetes and 30-40% Chronic Kidney Disease: an increasingly common multi-morbid disease
in need of a paradigm shift in care !
- 30. Diabetes & Potassium – Very Important For Heart & Health !
- 31. ADA & Co. Keeps You Sick By Its Hugh Conflicts of Interests !!
- 32. Type 2 Diabetes Can Be Reversed !
- 33. HbA1c - A1C Diabetes And Cognitive Decline !
- 34. DK Approved Individual Intensive Quality Care As Less Costly & More Healthy !
- 35. Pre-Diabetes or Diabetes or Diabetic ?
- 36. Air Pollution Increases Diabetes Risks – No Surprise !
- 37. So Called Diabetes Cures At YouTube From Indian Sources ?!
- 38. HbA1c or A1C - Big Study Confirms Its Limitations or Use !
- 39. WHO – Therapies Standards 2018 !
- 40. Facts & Myths About Diabetes !
- 41. Better Test For Better Prognosis & Costs Savings !
- 42. World New T1D-Trial Treatment !
- 43. Diabetic Amputations Increasing !
- 44. Pharmacists Lead Diabetes Initiatives !
- 45. US Diabetics Die By No Money For Medications !
- 46. Eyesight Loss or Blindness Is Preventable – We Blind To This Facts ?
- 47. Japan – Diabetes T2D Maybe 10 – 20 Years Before Identified !
This List gets continuously completed also by each Topic information
getting improved, completed or up-dated as soon as New- or Better
Know-How is available.
Objective Diabetes Standards & Guidelines
This purely scientifically, physically and practically made to handle the epidemic.
( It’s Not Made by Poker-Table ADA Set 12 People Only Committee, where world
recommended Professors & Doctors in Diabetology - Endocrinology and General
Medicine may missing. The present Diabetes Epidemic cannot be handled like this.
Where are such as Prof. Dr. M. D. or Prof. Dr. M. B. Zimmermann, Etc. ?
Presently worldwide registered T1D, T2D, LADA, MODY, Etc. Patients of about
500 Million by the dark number for Pre- or Age- Diabetes of about 1 Billion.
This by an Increasing Trend according of WHO - World Health Organization ! )
For Normal Healthy People
Fasting Glucose less 100 mg/dl ( This also by ADA )
A1C max. 5.2 % or Average Glucose 91 - Max. 103 mg/dl ! ( This not made by ADA )
This by world recommended Professors & Doctors in General-, Cardio-, Neuro-, Endocrine- Medicine
since over 40 Years successfully applied and by NIH.Gov approved as seen here by its 2010 Link:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911067/
For Pre- or Age- Diabetes
Fasting Glucose 100 – 125 mg/dl ( Av. Glucose of 125 mg/dl = A1C 6 %. This also by ADA )
A1C 5.3 - 5.9 % or Av. Glucose of 105 – 124 mg/dl. ( This not made by ADA )
If Pre-Diabetes by Fasting Glucose is confirmed an OGTT 75g Test should been made with
the 1 Hour-Result of 145mg/dl or higher as First Priority To Use by its better sensitivity or
reference To Detect Pre-Diabetes compare to the 2 Hour-Result of 130 mg/dl or higher ( This mg/dl not made by ADA ).
( Continuous Glucose of 105 mg/dl known as beginning of Micro-Macro-Vascular Blood Circulation Disorders to see by the
beginning of swollen Feet. As also seen here in the NIH.Gov 2010 Link, Pre-Diabetes of A1C 5.5 - 6 % compare to Healthy 5 %
has already a Double-Risk for Heart-Failures and therefore should been treated by Therapies Medications & Lifestyle to get
into the Average Glucose Range of 91 - Max. 103 mg/dl as for any Normal Healthy People. This not made by ADA )
By ADA anyone with A1C of less 5.7 % is as healthy as someone with a Healthy A1C of 5 % - How Wrong They Are !
( ADA by high A1C Recommendations putting Diabetics at Heart- Etc.- Risks and resulting calling for Heart- Medications
with Potential Cardio-Vascular and Heart- Health Benefits, But Which One ? – It’s Unbelievable ! )
For Diabetes
Fasting Glucose higher 125mg/dl ( This also by ADA ).
A1C 6% or higher ( The new 6% has the ability to confirm diabetes as good as the OGTT can, it also means if any 6% A1C
Result is achieved, that an OGTT 75g Dextrose Test should been made for reconfirmations ( The A1C 6% not made by ADA ).
OGTT 2 Hour-Result of 180 mg/dl or higher to confirm diabetes ( The New 180 mg/dl as 10 % lower not made by ADA ).
( Good Diabetes Therapies should allow to have the Glucose within the range of any Normal Healthy People ! This not made by ADA )
Therapies Related Measures For Any Diabetes Types
-- Any Basal-Medications as 24h Insulin- or Other- Long Acting Medications, Metformin, Etc. within
the Daily 24 Hours Cycle At Lowest Fasting Glucose Set within 80 - 90 mg/dl to avoid Hypos but providing
the best preconditions for A1Cs as of Normal Healthy People as following ! ( This not made by ADA )
-- General Target HbA1c or A1C for Any Diabetes Type, Age, Gender:
4.8 - 5.2 % or Average Glucose Range of 91 - 103 mg/dl ( This not made by ADA )
-- The Simple Therapy Rules For At Any Diabetes Types To Apply:
1. Fasting Glucose Value before or after any Meals 80 - 100 mg/dl !
2. During any Meals Glucose Above 100 mg/dl for Max. 2 ½ Hours !
( By This Any A1C Will Also Improve. This not made by ADA )
-- Metformin by lower D 3x dosing of Daily 375 - 750 mg to Support Therapies should been applied by Any
Diabetes Types to improve A1C and also to reduce known Heart Failure Risks and for this also generally
checking too low GLP-1 Hormone levels to possibly supplementing it ! See also at Topic 11. the use of
simple Non-Hypogenic Therapies for much better and healthy overall results ! ( This not made by ADA )
-- Every 2nd Day, by one day pause, 1/2 Standard Aspirin Tablet combined with Daily Vitamin-E 600 - 800 mg
and 3x Daily Slow-Release Prolonged Niacin 125 mg to open Blood-Vessels. All this for improving Blood-Flow,
reducing Blood-Pressure and resulting to reduce Heart Failure- and Neuropathic- Risks. ( This not made by ADA )
( At any Operations, Aspirin stopped 10 Days before and Vitamin-E or Niacin
stopped 2 Days before ! )
-- Supplementing Potassium by daily 900 - 1000 mg or eating 2 Bananas. See at Topic 17. ( This not made by ADA )
-- Standard Normal Healthy A1C 5% for Diabetics able To Avoid or Reverse Neuropathic Symptoms !! ( This not made by ADA )
-- Taking all Medications as required !
By all of this, every Patient or Doctor can see how it is or suppose to be and
can themselves decide about how much risks to accept.
All above modifications are communicated with NIH.Gov to become the Standard also at ADA !
If You Have A Question or Problem Until Now Without Solution ?
By Email you can contact us and we will reply with the answer made
by some leading Prof. Dr. in Diabetology - Endocrinology which
you then should discuss with your Doctor in Diabetology.
1. Diabetes-Related Microvascular and Macrovascular Diseases in the Physical Therapy Setting
Here from NIH.Gov the Worlds Medical Reference !
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579903/
The Basic-Cause of Neuropathy, Retinopathy, Kidney-Nephropathy, Bones-Osteopathy, Etc. of about
20 Additional Diseases up to Amputations.
The Related Venous Capillary Netting: https://en.wikipedia.org/wiki/Capillary
Feet’s should never been swollen because if swollen it confirms Micro- Macro-
Vascular Blood Circulation Disorders. To avoid swollen Feet’s it need the
Average Glucose at Max. 97 mg/dl. When Feet’s swollen for a Week and
the Average Glucose is made to be in range of Max. 97 mg/dl then it can
take 1 - 3 Months until the Capillary Netting Veins recover back to normal.
To Reduce the Diabetes Typical Blood Circulation Problems with its Inflammation
and Neuropathies Potentials.
As known Every 2-3 Days take 1/2 of Standard Aspirin Tablet, means taking it and
Pause for 1 - 2 Days then take it again, etc., this combined with Daily 600 - 800 mg
natural Vitamin-E !
As known To Reduce the Inflammation Potentials, Every 2nd Day take 350 mcg of pure
natural Selenium-Yeast without of any Magnesium-Stearate affecting the Selenium
properties and bio-functionality, but micro-crystalline Cellulose it could contain !
Selenium to preserve its Effect need to be taken 2 hours apart from any other
Medications or Substances or Supplements.
As known, the Aspirin will reduce the White-Blood-Bodies to stick together and the
Vitamin-E as known will reduce the Red-Blood-Bodies to stick together and by that
the Blood has an increased Flow-Capacity. As known Glucose is a sticky matter !
( As Important - 10 Days before of any Operations the Aspirin intake and 2 Days
before the Vitamin-E intake needs to be stopped ! ).
The Selenium is very well known for its huge Inflammation- or Infects- Reducing properties
and resulting is also reducing and eliminating Diabetic Pain !!
If under the above procedure swollen Feet's do not disappear, then you have to
contact your Doctor, because possibly you have also some Kidney, Liver, Heart,
Lungs, Thyroid, Digestion Problems or some Medication Allergy to take care.
At Acute Neuropathies reduce the A1C to 5 % Average Glucose of Max. 97 mg/dl
and take Every Second Day the 350 mcg Selenium as above, but in-between take
also only 250 mcg Selenium to strengthen- and preserving- its Effect.
By this in combination with above Aspirin & Vitamin-E plus daily Vitamin-B12 30 mcg
and Vitamin-B6 10 mg with 3x Daily Slow-Release Prolonged Niacin 125 mg ( B3 ) to
open Blood-Vessels, it’s possible to recover within 1 - 2 Years by the Feelings also
returning again.
About the Aspirin and other Supplements details and use have a look at Topic 17.
( For example Alpha Lipoic Acid provides too little recovery if any and is not solving the problems. )
If like to get Neuropathies it’s easy, just follow the ADA Guidance of 80 - 180 mg/dl Average 130 mg/dl
and this whereas known beginning from Av. 105 mg/dl or higher just get it, possibly also with Ulcers !!
2. HbA1c or A1C Values & Target Value !
Here is a Link for the Conversion of A1C New % DCCT- and New IFCC- Norms
with the Average mg/dl or mmol/l Values from A Certified German Laboratory.
By inserting the A1C New % or New mmol/mol Numbers it shows 4 Results
with the right relations to each others !
By shifting here the A1C Numbers you can find out about the relations of some
specific Average Glucose mg/dl or mmol/l Values show up.
( Sorry, anything like this could not been found in English )
https://www.labor-limbach.de/laborrechner/labor-rechner/hba1c-standardisierungeneinheiten/
It became pretty confusing with the A1C Numbers, because what
used to be A1C 5.4 % for Average Glucose 97 mg/dl became 5 %
and A1C 4.5 % was for Average Glucose 68 mg/dl it became 4 %.
Resulting for A1C we should apply Its Calculated Average Glucose Value Only
and that not higher than Average 97 mg/dl To Be Safe as within the Normal
Human Healthy Range of 70 mg/dl to max. 97 mg/dl or max. 5.4 mmol/l !!
More Examples:
By the Old System A1C 6 % was Average Glucose 117 mg/dl or
A1C 7 % was Average Glucose 149 mg/dl !
But by the New System A1C 6 % is Average Glucose 125 mg/dl
and A1C 7 % is now Average Glucose 154 mg/dl !
Diabetics get cheated ?
Therefore Use Only The Average Glucose Values mg/dl, because
mg/dl is mg/dl it cannot be changed by the same for mmol/l
We have now the problem of several A1C to Average mg/dl Calculators
in the Internet and also at Laboratory Reports, but rarely have specified
by which Norm they really functioning and so The Patients need to make
sure and possible need to do phone-calls to ask for the Average Glucose
Values mg/dl of its A1Cs to avoid any mistakes !!
General Target HbA1c or A1C for Any Diabetes Type, Age, Gender:
4.8 - 5.2 % or Average Glucose Range of 91 - 103 mg/dl
( By NIH.Gov, Av. Higher 103 mg/dl provides Increased Heart Complications. )
See NIH.Gov Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911067/
As known there is a problem with the Laboratories A1C Evaluations, where
depending on the kind of Equipments, Calibrations and Handlings the A1C
Results can vary by a disturbing Tolerance of plus-minus 12 % ( 24 % ) !!
Until today there are still not better Standards developed to avoid this.
Important About HbA1c or A1C Tests !
As a Doctor or Patient you need to make sure that you selecting the
Right Laboratory with the Right Equipment as necessary !
Regrettably there is presently worldwide only One FDA approved A1C
Equipment available which offers the Precision Tolerance of Less 2 %
and that is the Cobas Tina-Quant HbA1c Gen.3 as by the Link seen:
http://www.cobas.com/content/dam/cobas_com/pdf/product/Tina-quant-HbA1c-Gen-3/Tina-Quant%20HbA1c%20Fact%20Sheet.pdf
3. Diagnostic Standards
They regrettably not Physically based, but more by Convenience for Patients
or Doctors and Commercially for the Health Insurances, by the Therapies
Standards also under the same methodology, as for example compare A1C of
8 % the A1C of 7 % shows 12 % less Permanent Diseases, how the Rest % ?
According NIH.Gov Average Glucose higher 97 mg/dl ( higher Former A1C 5.4 % or
today’s 5.0 % ) shows already an Increased Heart Failures Rate at Normal People.
See here the NIH.Gov Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911067/
Now maybe some will say Diabetics are not normal people anymore, but
for us they’re also just as normal people with the same bio-anatomies !
By this it’s good to understand, Why at Diabetics under Therapy we recommend an A1C
of Average Glucose 91 - 103 mg/dl. This In The Best Interests of Diabetics People Only !!
Our Recommendation of Average Glucose 91 - 103 mg/dl also for as well known To Avoid
Swollen Feet’s or Neuropathies, Etc. caused by Micro- Vascular Blood Circulation Disorders.
As known the beginning of Swollen Feet’s starting from continuously 105 mg/dl.
Before 2008 by the Old Norm A1C 5.5 % was corresponding with
Av. Glucose of 100 mg/dl as the Max. for Normal Healthy Humans.
By the Old Norm A1C 5.5 % Av. Glucose 100 mg/dl and A1C 4.5 %
for Av. Glucose of 70 mg/dl as the Min. for Normal Healthy People.
The range for Normal Healthy People was Av. Glucose 70 - 100 mg/dl.
Then the Norm got changed from A1C 5.4 % to 5 % as Av. Glucose
of 97 mg/dl and A1C 4.5 % changed to 4 % as Av. Glucose 68mg/dl.
NIH.Gov by Big Study the A1C 5 % Av. Glucose 97 mg/dl got proven
confirmed as the ideal, because higher A1C causing Heart Failures
by A1C 5 % compare to 5.5 - 6 % the Risks Doubles !
See the Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911067/
But 2017 by ADA & Co. for Normal Healthy Humans is confirmed
the A1C of Max. 5.7 % Av. Glukose 117 mg/dl !!
How much more Fooling do we deserve ? ? ?
( It shows how the Diabetic Epidemic is handled or not handled by just creating
more So-Called Healthy Humans with higher Average Glucose than ever before ! )
We basically have about 20 Years old Standards by A1C 6.5 % Average
Glucose 140 mg/dl ( before 133 mg/dl ) or higher defined as Diabetes.
Under these recommendations as of ADA the present Diabetes Epidemic
developed worldwide. For This Will We Ever Get A Sorry ?
Newly since 2017 we got the Pre-Diabetes defined by A1C 5.7 % Average
Glucose 117 mg/dl or higher up-to A1C of 6.4 % and/or Morning Fasting
Glucose 100 - 125 mg/dl defined as Pre-Diabetes.
To handle the present Diabetes Epidemic within the next years we can
expect, but maybe already as from 2018, that Diabetes will be defined
from A1C 6 % Average Glucose 125 mg/dl or higher and A1C of 5.3 %
Average Glucose 105 mg/dl or higher to be defined as Pre-Diabetes
and Age independent Stage 1 Diabetic Therapies get developed for it.
Presently Only Forward Strategies Can Help Where The Diabetics First !
Today in Hospitals or Chirurgic Clinics we can see the Surgeons at
about 60 % occupied with Diabetics by vascular bypasses operations
and various amputations. This under the present Standards where
of such as the ADA it has never been seen any Press Releases.
4. Diabetes Awareness & Precautions
Since Sooner or Later In Life Anybody Could Get Diabetes. Therefore at every
household, beside the Thermometer, Blood Pressure Meter there should also be
a Calibrated Glucose Measuring Device to measure every 2-3 months.
The Glucose Measuring Device calibrated by taking blood for in the Laboratory to
measure the Glucose and at the same time to do 3 Glucose Measurements to write
down the numbers and date, for by the Lab Report later to know how much it may
shows too less or too much, because the cheap devices are usually not accurate set
by the producers. Measure every 2-3 Months the Morning Fasting Glucose Level and
if you have it within 100 -125 mg/dl, repeat the measure and measure it monthly and
contact your Diabetes Doctor, because you will have Pre-Diabetes maybe also age
related to aware and take care of by Therapy & Lifestyle as early as possible as
better it is to avoid any permanent affections.
Do Glucose measurements only at good cleaned Just Water rinsed and after well dried
Fingers without using any Disinfectants, Soaps, Crèmes or Lotions and for that purpose
reserve A Clean Towel to dry the Fingers, that’s very important for reliable values !!
5. The Simple Therapy Rules For At Any Diabetes Types To Apply:
1. Fasting Glucose Value before or after any Meals 80 - 100 mg/dl !
2. During any Meals Glucose Above 100 mg/dl for Max. 2 ½ Hours !
( By This Your A1C Will Improve. )
General Target HbA1c or A1C for Any Diabetes Type, Age, Gender:
4.8 - 5.2 % or Average Glucose Range of 91 - 103 mg/dl
( By NIH.Gov, Av. Higher 103 mg/dl provides Increased Heart Complications. )
See NIH.Gov Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911067/
6. Swollen Feet's & Higher Blood Pressure & Neuropathies Checking
By Diabetics The Blood Pressure as very important should been seen in combination
with the A1C !
This means that All Diabetics should also have an "Omron" Blood Pressure Meter at
home for at some Relaxed Moments to measure once weekly.
Measuring the Blood Pressure is as important as daily measuring the Glucose
and daily watching the Feet’s !!
The normal healthy Blood Pressure is Systole-High 110 - 120 mmHg ( Systole max. 140 mmHg )
and Diastole-Low 70 - 77 mmHg to keep in mind.
Diastole-Low is representing the Average Blood Pressure between the Heart-Beats
and resulting the most important pressure to watch.
Diastole-Low of 80 - 89 mmHg is Risky Pre-Hypertension and at Diabetics confirm
Initial Blockage Micro- Macro- Vascular Blood Circulation Disorder in The Body’s
Capillary Veins Netting and resulting Swollen Feet’s and A1C above the
Recommended Average Glucose of 91 - 103 mg/dl !!
Diastole-Low of 90 - 99 mmHg confirms Stage 1 Hypertension - Higher Risks.
Diastole-Low of 100 mmHg or higher confirms Stage 2 Hypertension - Highest Risks.
Risks for Cardiovascular Complications and for Neuropathies, Etc. ! ! !
Watching The Feet’s At Daily Base
During the day and especially when doing some sitting work it is normal that
until the evening the Feet’s will have a tendency for some little swollen, but
the Veins should remain visible and not begin to disappearing by swollen.
In the morning when getting out the bed, the Feet’s should never been swollen
and if swollen it confirms something wrong with the Therapy Parameter Setting
and Resulting the A1C Too High and you also at Neuropathies Risks !!
If something is wrong with the Therapy Parameter Setting, you either experienced
by yourself to adjusting it or you contact your Doctor in Diabetology to be sure.
Monthly Check Your Feet’s For Neuropathies
At Sole of the Foot and Toes by a Ballpoint-Pen by gently touching to draw Lines
everywhere You should been able to create some Tickling-Feeling if OK and otherwise
if you feel nothing you will have Initial Neuropathies and when you partially not even
feel the Pen touching or its pressure on the Skin you will have Acute Neuropathies
to take care of by immediately reducing your A1C to the well recommended Average
Glucose of Max. 97 mg/dl and apply some medications to improve the Blood-Flow
and reduce Inflammations as here initially introduced at the Micro- Macro- Vascular
Blood Circulation Disorders.
For this have a look at initial “Diabetes-Related Microvascular and Macrovascular
Diseases in the Physical Therapy Setting” from NIH.Gov with related Comments !
As here seen; Swollen Feet’s, Higher Blood Pressure and Neuropathies are interconnected !!
7. When You Get A New Insulin-Pen To Use !!
You should first apply the two steps setting Procedure as following:
1. Take the Pen without inserting any Needle and set 5U for gently press until
you cannot complete it to reach Zero U because you feel a resistance. At that
moment do never forcing to reach the Zero for not breaking the mechanics.
2. Then insert the Needle and press to Zero by some Insulin drops coming out.
You need to see some drops coming out.
If you do not apply this Setting Procedure, the internal mechanism at the
Piston is not at Zero and resulting your first Dose will be incomplete ! ! !
8. Calibrations at CGM-Continuous Glucose Monitoring Systems
If you are a user of any such system as it preferably to be, then read
carefully about the important daily calibration, for things not going wrong.
You should never not doing any calibrations or not applying comparisons
also at systems even the producers may say “no need of calibrations”.
At any CGM-System when you change the Sensor apply at the first day
at least 2 Calibrations, by the first one 1-2 Hours after replacing it and
8 Hours later a second one to make sure !
As you know the measurement is made in The Tissue and not directly in
The Blood Flow as principally necessary for any Real Time Measuring.
Measuring in the Tissue as known has a time delay of about 10 Minutes
where it can go Up or Down in the blood stream and therefore to
have a good calibration, the calibration should always been made at some
period where at the monitor is seen that the Glucose-Level is going Flat
Horizontal for some time usually between the meals or 4 hours after
any meals or drinks, beside of water drinking only !! !!
By this kind of calibration method you could then also see that sensors
been used for longer, become even more precisely with less to correct.
( If not yet have a CGM-System but like to decide to get one, then decide
only for a type able to connect with some Insulin-Pump System to use in
the Close Loop configuration, because only that will give real advantages
as for example At Night To Stop any Insulin Supply when going to Hypo
and if may like to decide to get a Insulin-Pump System, then decide for
one able to use by Close Loop Application combined with CGM-System.
For example Metronic has a Insulin-Pump System where the CGM-System
is integrated means there is only One Patch on the Abdomen to wear. )
https://www.medgadget.com/2014/06/medtronic-minimed-duo-integrates-glucose-sensor-insulin-infusion-into-one-device.html
9. Important Information’s For Basal-Insulin Users And Patients
There is a strategy applied by the Insulin Producers to respect its Doctors Clients
discretion only to create consultations to pay for, where even Diabetes- Associations
or Communities or Forums, Etc. participate with and therefore Important Practical Info
For The Diabetes People Applications, regrettably are not published, but here will all
this been compensated by all important details herein shown as following.
Generally, All Patients by The Laws are permitted to know everything’s about its
Diseases and Medications, where the Health Industry is obliged to provide All
Related Information's, but this is not completely fulfilled as regrettably seen !
( This by Doctors and Companies supported who welcome the contrary. )
10. Injection Technique / Basal-Insulin
Selecting The Right Injection Location
With the Needle-Point first carefully Test The Skin-Locations if you could
feel it or not, for if you feel it, just select another location where you
feel nothing or not much and then do there the Injection to have it
painless and also to be more save for not getting any blood vessels,
because usually near blood vessels there are also more nerves to feel !
Insert the Needle slowly and if you start to feel some pain do not insist
just retreat and pullout the Needle and select another location to have
it painless and resulting also without any bleedings after the Injection,
this usually by counting slowly to 15 before pulling out the Needle.
Bubble Problem
If there is a Bubble in the Insulin-Pen it’s sometimes not so easy to get it
out and Big-Bubble can influence the Dosage, because the Bubble-Gas can
be compressed where any Liquid could not been compressed. Therefore if
the Bubble could not been eliminated, then apply the Injections by instead
counting slowly to 15, count slowly to 25 before pulling out the Needle !
By this procedure the Dosage will be OK, because the Bubble has enough
time to lose its Gas-Compression.
If possible, bleedings after the injection should been avoided, especially
at 24h Basal-Insulin, because with the Blood also Insulin comes out and
then the Doses is not right anymore and it could not been corrected.
After injection have a look for about 20 seconds to see if some
bleeding at the injection location occurs or not.
In case of Any Bleeding, after 10 - 15 seconds just quickly use the Finger-Tip to
block it by some gentle pressure to keep for One Minute To Stop The Bleeding.
In case you have Bleedings from the moment when you pullout the Needle
then do not use any pressure or Fingertip just some clean toilet paper to
absorb the Blood and let it bleeding until it stops by itself. This can happen
when you incidentally as rarely puncture some little vein at Insulin injection
and that’s why you should let it bleeding for as much as possible Insulin
coming out together with the Blood. If you do not let it bleeding and press
with your Fingertip to stop it, then the effect will be as if you Intravenously
injected the Insulin and resulting quickly within 10 minutes get a strong Hypo
you would need to fight against it with sugar. Therefore if this happens just
5 - 10 Minutes later measure your Glucose and if below 70 mg/dl quickly
take some sugar drink for not waiting for the stronger Hypo !! !!
Therefore it’s better to take the time it need for all the Injections.
Do not share your Insulin- Injections or Pens with Other People, even if the needle
has been changed. You may give other people a serious Infection, or get a serious
Infection from them ! ! !
Basal-Insulin
The Basal-Insulin should been injected at body locations where there is not a strong
blood circulation to provide the good 24 hours effect it really should have to be basal
only. It therefore is good to be applied Abdominal or at Upper-Legs if there is enough
fat underneath the skin as usually at Legs more by women’s exists.
The Basal-Insulin should subcutaneous been injected into the low blood circulation
Dermis of about 5 mm thickness underneath the Skin of about only 2 mm thickness.
To achieve this it is proposed to use Ultra-Fine 0.25 x 8 mm Needles by injecting it
Diagonal at about 30°- 45°degrees angle to get it underneath the Skin into the Dermis
and when by the Insulin-Pen the complete Dose is injected, for counting slowly to 15
before pulling out the Needle to ensure the complete Dose as set is really injected,
to see by afterwards not having any Insulin-Drops coming out of the Skin.
Using Needles not shorter 8 mm is also to ensure that after injection not any Insulin is
coming out of the Skin in combination with counting slowly to 15 to make sure. Inject
into the Dermis it also means usually not even feeling any pain at injections, because
the Dermis has not much of nerves or blood vessels either.
The 24H Basal-Insulin as Toujeo or Tresiba always set to Lowest Fasting Glucose of 80 - 90 mg/dl.
Toujeo or Tresiba are worldwide the only Real- 24H- Flat- Horizontal- Diagram- Line Basal Insulins
any Modern or Better DM-Therapies requesting for any necessary Therapy- Bases !
24H Basal- Insulin- Injection- Rule:
If not sure to have the Daily- Dose Injected or Not Injected, then Skip the Daily- Dose And Not Inject It
to be sure that there could not be any Double- Doses possibly causing 24H Hypos as very dangerously !
It’s better to have the Risk of maybe just for One Day No 24H Basal-Insulin with higher Glucose mg/dl,
instead possibly unknowingly risking to have any Too High Daily- Double- Dose For Extreme Hypos.
10.A) At Rapid-Insulin Applications
At any Rapid-Insulin to be applied at meals or snacks or any corrections, we have the
contrary situation of Basa-Insulinl to use Ultra-Fine 0.25 x 8 mm Needles by Injecting at
45°- 60° Degrees to get a little deeper into the little more blood circulated Fatty Subcutis
for a better and faster Insulin Reaction. At Rapid-Insulin the effect start should be within
10 - 20 Min., but some have the effect start at up-to 1 Hour or more and they should
resulting do Intra-Muscular Injection by 12 mm Needles at Upper-Arm Muscle to get
the same 10-20 Minutes !
Here also, when by the Insulin-Pen the complete Dose is injected, for counting slowly
to 15 before pulling out the Needle to ensure the complete Dose as set is injected.
For Safety apply Rapid-Insulin at Eating- Start or Soon After and set the Units for that
conditions to be safe and possibly measure the Glucose 3 Hours after Eating-Start to
apply some corrections if the Glucose is still above 100 mg/dl and this by the Units
Calculation Base as from 80 - 90 mg/dl always to be applied !!
( If you know well your Time of Rapid-Insulin Effect-Start, you should by that Time
Inject before the Eating-Start, for additionally reducing the Glucose-Increasing ! )
It’s Important that you Evaluate your Rapid-Insulin Unit-Factors to find out how much
Glucose mg/dl Reduction you personally get Per-Unit and for quantities of Carbon
Hydrates to Apply Calculations and this You have to do in combination with your
Basal-Insulin applied, because the Basal-Insulin Dose is also influencing the
effectiveness of The Rapid-Insulin Unit-Factors !
In such cases where the effect of Rapid-Insulin is drastically delayed and therefore
IM-Intra Muscular Injections are the possible solution to get the Reaction-Time to be
as normal by 10-20 Minutes, anybody should prior discuss this with the Doctor and
possibly apply the First Such Injections under the Doctor's Observations and Glucose
measuring as very important for not causing any Insulin-Shocks may resulting !! !! !!
10.B) Hypoglycemia - Hypos - Low Sugar - Cramps, Can Also Occur By Rapid-Insulin
Is defined by Blood-Sugar less 70 mg/dl or practiced by less 60 mg/dl since
even healthy People by some Sports, Sex, Etc. body activities can reach 60 mg/dl.
For corrections it should been taken care for not going from one extreme to
another and therefore is the following procedure proposed.
Take 2 Sugar-Cubes of about 8 grams or one Heaped Teaspoon Sugar which
is also about 8 grams mixed in warm Water to drink and it will increase the
Glucose by about 25 mg/dl within 30 minutes, measure the Glucose 30 - 40
Minutes later and if still a little too low repeat the same until you have
the Glucose stabilized at higher 85 mg/dl !
The impact of Body Training or Exercise or Sex related to Hypos need to be
considered by taking up-front some carbon-hydrates and about every 40 - 50
Minutes possibly some Sugar-Cube or Crackers, Etc. and afterwards checking
Glucose Levels by its after effect to possibly eat something to avoid Hypos !
Aware of Hypos Symptoms !!
Concentration Reduced, May Trembling Hands, Sunlight or Strong Lights Blinding,
Dizziness In The Head, Increased Hunger Feeling, The Balance At Walking A Little
Disturbed and Some Can See A Yellowish-Greenish Illumination At Closed Eyes or
In The Dark At Very Low Sugar, Wakeup At Sleep and The Sleeping Disturbed.
Hypos by Too Low Glucose Could Also Cause Cramps. If this happen take
some Magnesium-Liquid combined with Sugar-Water to relax the muscles
and to increase the Glucose and the Cramps will very quickly disappear !
Cramps get also By Blood-Circulation-Disorders In The Muscles Created
and therefore Diabetics should take every second day Aspirin with daily
600 - 800mg Vitamin-E !!
To have no hangover from stronger Hypos you should supplement
Potassium of about 1000 - 1200 mg or eating 2 1/2 Bananas !!
Strong Hypos do consume Potassium and it gets quickly too low.
The best to avoid Hypos is by using a Therapy with only Non-Hypogenic
medications where even a much better Glucose control can been achieved
with resulting much better and healthy A1C Values, but there is not much
existing of Non-Hypogenic.
As Non-Hypogenic there is only Metformin as Glucophage SR or XR the best,
possibly combined with Glucobay and possibly also combined with a 24 hours
Basal-Insulin such as the well known Toujeo.
Hypoglycemia https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0024700/
About Hypos Handling Have Also A Look At Below Point 18. In Combination With Alcohol.
10.C) Hyperglycemia - Hypers
This is usually defined by Glucose above 100mg/dl, but mainly by the meaning
of Glucose 150 - 400mg/dl as example and not so much related to the Glucose
increase at any Meals which by the right Injection-Factor should been corrected.
It also means when the Glucose even without eating anything goes to 200mg/dl
or higher as it also possible by any Infections or by the Liver as uncontrolled.
For if the Glucose surprisingly is really high, it is Good To Apply The Rule
of 1. Measuring Again at cleaned Fingers and 2. Not More Than Maximum 5 Units
Rapid-Insulin To Inject At The Time and control the Glucose after 1 ½ Hour and
if necessary apply again Max. 5 Units Rapid-Insulin to check again after 1 ½ Hour,
Etc.
This is the System for by Steps gradually reducing the Glucose for not getting from
One Extreme Into Another and gradually not so fast coming down is also better for
the Body and also for not maybe too easy getting into any Hypos by surprise !
High Hypers create also dizziness, but additionally some tiredness where at
Hypos The Contrary of awakens is because of the Body On Alert .
Applying The Rule of Max. 5 Units Rapid-Insulin For Reducing High Glucose is also
For The Safety for when maybe Stupid or Unwanted Things happen where always
More Than Just One Factor Comes In Play At Such Situations !!
Stupid Things like measuring the Glucose at not cleaned Fingers or the Towel
where the Hands got dried after cleaning did have some Sugar Containing
Substances or Rest of Lotions or Syrup and For This Is The Second Rule To
Be Applied - As At Any Unexpected or Extremely High Glucose Measuring To
Always By Again Cleaned Fingers, Repeating The Glucose Measurement !! !! !!
For example when someone feels a little dizzy and like that is quickly doing
some measurement ( at unaware dirty fingers ) and the reading shows high
Glucose of for example 300 mg/dl, where in reality its low Glucose by the
dizziness and would apply the Rapid-Insulin correction by the Usual Injection-
Factor, Instead By The 5U Rule, then there is not much of a chance to survive
when as Too Late the Rapid-Insulin-Effect kicks in and simultaneously also a
Potassium-Hypo get created by The Too Quick Glucose Falling where finally
the Heart-Beat Can Stop by Lack of Potassium !!
Hyperglycemia https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0024701/
https://www.ncbi.nlm.nih.gov/books/NBK430900/
10.D) Glucose Measuring - Lost Insulin Effect
Normally there should been several Glucose measuring during the day if you
have no CGM-System as preferable.
-- Generally the very first Fasting Glucose Measuring in the morning is one of
the most important, because only that one can show you clearly how your
Basal-Setting works or if something has changed by your Diabetes and
resulting need to adjust. It also means if you do not daily so many Glucose
Measuring, then at least the very first one for Fasting Glucose in the morning
you should every day do to be aware about your Basal- Insulin or Medication
Setting. For how to set the Basal-Therapy have a look at Point 3.
-- At Meals you should 3 Hours afterwards do some Glucose Measuring and if
necessary by your Insulin Unit-Glucose-Reduction-Factor-mg/dl you need to
evaluate for at over 100 mg/dl doing the necessary corrections.
The Simple Therapy Rules For At Any Diabetes Types To Apply:
1. Fasting Glucose Value before or after any Meals 80 - 100 mg/dl !
2. During any Meals Glucose Above 100 mg/dl for Max. 2 ½ Hours !
( By This Your A1C Will Improve. )
Lost Insulin Effect
This is now something we all hope will never happen, but it could happen within
2 - 3 Days or Weeks or Months or Years, by the body’s immune system producing
Too Much of Antibodies Against It and by that quickly or gradually it can lose
the Effect.
When it happens quickly it can easy been realized, but when it happens gradually
it becomes a little complicate, because of the uncertainty if the Diabetes Has
Changed ? or just the Insulin-Effect ? or Both ?
-- For example if Basal-Insulin and Bolus-Rapid-Insulin at Meals are applied and if
at certain Meals the Rapid-Insulin Doses drastically increases, but the Basal-Insulin
Dose as good remains stable by the morning Fasting Glucose Measuring confirmed,
then we can see that the Rapid-Insulin Effect is reduced and therefore need to be
changed to some Other Type, because increased Insulin-Resistance could not be
the case since the Basal-Insulin remained stable.
Here if the Meals Rapid-Insulin Doses remain stable, but not the Basal-Insulin
Doses as confirmed by the morning Fasting Glucose Measuring and resulting
drastically need to increase, then we have to change the Basal-Insulin Type.
-- Now if both changed Basal-Insulin- and Meals Bolus-Rapid-Insulin- Doses,
then we usually assume, that increased Insulin-Resistance is the case and
resulting Adjust the Doses, because having the Effect lost at two different
kind of Insulin all at the same time is really very rare, but not impossible.
11. New Anti-Hypogenic Combination Therapy by Metformin, Glucobay, Januvia for T2D + T1D.
This is for Type 2 Diabetes and some possible support at Type 1 to achieve Better A1C !
Metformin Medications are registered as also in combination with Insulin, Etc.
Metformin as the best for controlling or reducing Liver-Glucose-Production
and additionally has also some small Insulin-Sensitivity increasing effect.
The Metformin has a Half-Value Time of 3 Hours after its maximum in the
Blood called Tmax. That means when swallowing it takes about 2 ½ Hours
to reach the Tmax Plus the 3 Hours resulting to 5 ½ Hours after swallow
and only the Half Amount or mg is remaining for the resulting Half Effect.
Under this consideration Metformin by the Daily Dose should been divided
to take it at least by 3x Daily every 8 Hours or better by 4x Daily every
6 Hours for the necessary 24 Hours effectiveness !!
For convenience can the Daily Dose also been taken by Slow Release or
Extended Release as for example the Glucophage SR or XR but here is
to mention that the Tmax. is only 7 Hours and that means it lasts only
for 14 Hours as the double of Tmax. and therefore the Daily Dose should
be taken 2x Daily every 12 Hours for necessary 24 Hours effectiveness !!
( Glucophage SR or XR is only called once daily, but has no 24h Effect. )
Its Basal-Effect at Morning Fasting Glucose to Set At 80 - 90 mg/dl !
For Type 1 Diabetes 3x Daily 125mg ( as 1/4 of round 500 mg with
Tablets Divider ) has the advantage to control the Liver-Glucose for
better A1C or HabA1c Values and handling the Glucose Control and
is preferable compare the Glucophage SR 500 mg for the same purpose.
By this can have an A1C of 5 % ( Old 5.4 % ) or Average Glucose of
88 - 103 mg/dl without any Hypos just as any Normal Healthy People !
( This naturally with the Right Insulin Settings as herein described. )
It shows also advantages by reducing the known Heart Risks at Type 1
as here seen in the Link: http://thediabeticnews.com/type-2-diabetes-drug-may-slow-heart-disease-for-type-1-diabetics/
Regrettably until today is No 24 Hours Release Metformin available
and Metformin is not causing any Hypos as sometimes described !
General Type 2 Metformin Dosing
1. For Pre-Diabetes 3x Daily 250 mg or 500 mg ( 250 mg of divided 500 mg Tablets )
or by the Extended Release Metformin SR or XR by 2x Daily 500 mg or 750 mg.
2. For Diabetes 3x Daily 500 mg or Max. 850 mg or by the Extended Release
Metformin SR or XR by 2x Daily 750 mg or 1000 mg.
3. The Dosing should been Set to Morning Fasting Glucose of 80 - 90 mg/dl and
if this with solely Metformin cannot been achieved, then it means that it should
also been combined with some other Glucose Reducing Medications.
4. Based on the main Effectiveness of 6 Hours it need the 3x Daily or at the
Extended Metformin SR or XR Effectiveness of 14 Hours it need the 2x Daily !
( If this Metformin dosing is not enough to achieve the Lowest Fasting
Glucose of 80 – 90 mg/dl as it normally should be, then the additional
use of any 24 hours Basal-Insulin as Toujeo should been considered !
This provides a simple but very effective Combination Therapy without
any Hypos possible when the 24 hours Basal-Insulin is right adjusted.
This as the best way, because not using any Hypogenic medications. )
Metformin Characteristics At Type 1 Diabetes where the Metformin is been
combined with the Insulin-Therapy for better A1C by better Liver controlling,
but here is to mention that Daily 3x 125 mg ( as 1/4 of 500 mg Tablets )
will not allow to gain or losing weight and at any Daily Doses above 375 mg
as higher above as more weight losses need to be expected !
At Daily only 2x every 12 hours Metformin 125 mg as 1/4 of the 500 mg,
small weight-gain at Daily 250 mg is gradually possible as experienced,
but the Glycemic-Effect is not as good as by the usual 3x Daily.
For Example, if have a Therapy A1C of 6 % and combine with Metformin can
have an A1C of 5 % or Av.- Glucose of 97mg/dl by an improvement of 1 % !
( Funny, the ADA does not inform about such matters. In favor of the Pharma Industry
do they like to keep the People sick ? )
The Simple Therapy Rules For At Any Diabetes Types To Apply:
1. Fasting Glucose Value before or after any Meals 80 - 100 mg/dl !
2. During any Meals Glucose Above 100 mg/dl for Max. 2 ½ Hours !
( By This Your A1C Will Improve. )
The Metformin Intake for at any PET-Tomography needs 2 Days before
been stopped. By about 94 % within 16 Hours by Urinating and in the
Plasma or Tissue the 6 % take one more Day to be out of the Body
where Metformin remains stabile and does not form any Metabolites.
Before Operations the Metformin 1 Day before need to be stopped.
The best to avoid Hypos is by using a Therapy with only Non-Hypogenic
medications where even a much better Glucose control can been achieved
with resulting much better and healthy A1C Values, but there is not much
existing of Non-Hypogenic.
As Non-Hypogenic there is only Metformin as Glucophage SR or XR the best,
also combined with Glucobay and Januvia by possibly also combined with a
24 hours Basal-Insulin such as the well known Toujeo or Tresiba only at the
Right Setting applied.
Metformin and/or Statin combined with Cancer Therapies :
https://www.forbes.com/sites/arleneweintraub/2018/06/07/how-an-old-diabetes-drug-made-a-big-splash-at-cancers-biggest-confab/#1c7af09a4ac1
Glucobay 50 mg – Take 3x daily every 8 hours ½ Tablet or 1 complete Tablet
if the effect of ½ Tablet is not enough for better BG Control.
The Daily Normal Max. Dose of Glucobay Is 300 mg and get adjusted by
the Fermenting Pops-Effect to of what is not been felt as disturbing !!
Glucobay prohibits Normal Sugar to enter the Blood and by this supports a
much better and easier BG Control and therefore at any may possible Hypo
usually caused by the Fast Bolus-Insulin too high Units or wrong set 24H
Basal-Insulin, as important resulting instead Normal Sugar only Dextrose
can been used to increase the BG !!
Glucobay itself is not causing any Hypos and can been used with any Diabeticas.
Januvia 25 mg – Take 2x daily every 12 hours 1 Tablet or the 50 mg Tablet
if the 25 mg Version is not enough for better BG Control.
The Daily Normal Max. Dose of Januvia Is 100 mg and get set to this level
if the morning fasting Glucose cannot be reached as within 80 - 90 mg/dl !!
Januvia as a smart generation of medication is only effective when the BG
is higher as normal and therefore Januvia itself will never cause any Hypos
and can been used with any Diabeticas.
Resulting any Hypos may caused are by the Fast Bolus-Insulin too high Units
or wrong set 24H Basal-Insulin. ( 24H Basal-Insulin is only Toujeo or Tresiba to know well. )
Januvia is only functioning, if the Pancreas is still producing own Insulin.
At any Anti-Hypogenic Therapies, all above 3 Medications by Metformin, Glucobay
and Januvia, independent of any additional Insulin, should always A1C Independent
being applied and not interpreted as Over-Therapy, because this combination
does not only provide much better and healthy A1C as at any Normal People,
but also provides a much easier better handling where not for every little snack
or biscuit any BG Corrections necessary and by this improves the life comfort !!
If by all above possible Doses-Adjustments, the necessary morning fasting
Glucose of 80 - 90 mg/dl cannot been reached, it would mean that some
24 Hours Basal-Insulin as only Toujeo or Tresiba would also need to be
applied to achieve finally the Necessary Morning Fasting Glucose Level !!
This can be in combination with Basal-Insulin such as Toujeo or Tresiba
and when right adjusted remains as Anti-Hypogenic, but when combined
with Meals Rapid-Insulin then from there only is has some Hypo risks.
For this Anti-Hypogenic Therapy System it’s necessary to apply and combined and individually
adjust all above 3 Medications plus eventually also Basal-Insulin if the Morning Fasting BG of
80 – 90 mg/dl cannot been achieved or also applied Rapid-Insulin if 2 ½ Hours after Meals
less 100 mg/dl is not reached.
This innovative New Anti-Hypogenic-Therapy is by us under the best
science & practical experiences developed in cooperation with world
leading senior Profs. Drs. in Endocrinology and get to any Patients
individually adjusted and by this gets universal for at any Diabetes
Types to apply. Just the Januvia at 100 % T1D Patients is useless.
Keep in mind, that Diabetes Therapies are just to control Glucose.
12. How to set the Basal-Insulin Dose as very important for the Necessary Base Effect.
Definition of Basal-Insulin: As the wording Basal says it means The Basic Base.
Basal-Insulin to be Basic need to have the characteristics of 24 Hours Effectiveness with an
Effectiveness-Diagram by some Continuous Horizontal Flat-Line Without Any Hypo-Mountains
to be able to act Basic and fine setting it as necessary without any Hypos !!
Regrettably are presently only Two Such 24 Hours Basal-Insulins in the world market
named Toujeo and Tresiba as from Europe where there is none from the USA.
For this it is necessary to take the time it needs to do this correctly and over many Days or
Weeks by a step by step procedure according the lowest Fasting Glucose Level at Night and/or
in the Morning after sleeping, or Whenever during the Day the Lowest Glucose Level will be to
find out very carefully for then At The Lowest Point by small steps of only 1 Unit adjusting it
to 80 - 90 mg/dl or 4.4 - 5.0 mmol/l only.
Apply just every 4 - 5 Days one adjustment and observe by measuring, because The Metabolism
needs 3 - 4 Days to find its final answer or balance.
By this procedure and since the Glucose Is Set at the lowest point within of 24 hours,
it makes it impossible for the Basal-Insulin to create any Hypos, but it provides you
the preconditions for the Best A1C you need and that means, if any Hypo occurs
it can be from Rapid-Insulin Dose at Meals only to know well about !
This is very important for the right preconditions for at Daytime in combinations with the
Rapid-Insulin as usually at Type 1 Diabetes or at Type 2 Diabetes where Metformin 30 Min.
before of any meals in combination with the Basal- Insulin is applied.
Only by setting the Basal-Insulin as above, the necessary very good HbA1c or A1C of only
Average Glucose 91 - 103 mg/dl or 5.0 - 5.7 mmol/l for No Neuropathies or No Retinopathies,
Etc. Affections possible by without any Hypoglycemia’s !!
The A1C of Average Glucose 91 - 103 mg/dl as of Healthy People, by what’s good for Healthy
People is also good for Diabetes People since they also just People or Humans and we all
know it’s not that easy to achieve, but by the Basal-Insulin Therapy Base not set or adjusted
properly, it could never been achieved ! ! !
This is related to Any Type of Diabetes where it has been decided to apply
Insulin or a Mix. of Medications by Insulin also in combination with other
Medications.
About this you should speak with your Doctor or for any reconfirmations contact
also the Insulin Producer and they will confirm the procedure as above described,
as only perfectly correct to be handled like that.
General Target HbA1c or A1C for Any Diabetes Type, Age, Gender:
Max. 5 % Tol.+0.2 -0.2 or Average Glucose Range of 91 - 103 mg/dl
( By NIH.Gov, Av. Higher 103 mg/dl provides Increased Heart Complications. )
See NIH.Gov Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911067/
13. About Glucose mg/dl !
The normal range at healthy People is objectively 70 - 97 mg/dl ( 100 mg/dl by
objectively is already too much and just a nice old number only. ) What is OK for
Healthy People is also OK for Diabetes People, since they also just People or Humans !
The healthy People have a HbA1c or A1C of Average Glucose 91 - 103 mg/dl or by New
DCCT-Norm 5 % ( It used to be 5.4 % by the Old-Norm ), but for convenience only the
Doctors will to Diabetes People reiterate the failed ADA Guidelines / Recommendations
to have HbA1c or A1C of 6 % or less 7 % and if Older even 8 - 9 % as to be OK
Only For Impression Purposes and when asking them, would a healthy HbA1c or A1C
of Average Glucose 91 - 103 mg/dl not been better as for any Healthy People to be
On The Save Side for not getting any additional affections ? , then all Doctors will
inform, if could achieve that naturally would been Superior ! ! !
At Healthy Peoples it can also happen, that temporarily the Glucose falls to about
60 mg/dl only by for example doing sport, sex, but this is no problem still aware of
everything’s and soon get again above 70 mg/dl, but when reading some Diabetes
Associations Info to scare Diabetes Peoples, below 70 mg/dl would be Hypoglycemia as
a Clinical Condition to desperately call 911, instead to Drink Just Some Soft drink or
taking a Sugar-Cube ! At less 50 mg/dl it usually gets a little dizzy just to take some
Sugar-Cubes.
An average Glucose of 97 mg/dl represents HbA1c or A1C of 5 % by New DCCT-Norm
( or 5.4 % by the Old-Norm ) and since 2017 the Fasting Glucose of 100 - 125 mg/dl
is already Pre-Diabetes to possibly apply Some Therapy.
The International Diabetes Scientists Committee by its new 2017 Standards decided
that the earliest possible to treat Diabetes by Therapy, the better it is to keep
Diabetes at lower intensity level, at Type 2 possibly to reverse and to avoid
any permanent affections.
14. About Diabetes Therapies In General
If years ago it was clear that Type 1 gets Insulin and Type 2 gets Medications such as
Metformin, Etc. as since over 50 Years, it today is differently applied. As seen, Doctors
more and more prescribe the Individual Patients also Individual Therapies where just
anything useful for the Glucose Management gets applied.
Today are certain T2D Mediations for better T1D A1Cs get combined with Insulin-Therapies.
There are no Narrow Minded Stigmas or Taboos anymore and anything for individually better
and/or more easily Glucose-Controls is legitimated.
This also under consideration, that much more Types of Diabetes exist and Not Only
Two Kinds, but for example even combinations of Type 1 with also Type 2, Etc., about
10 different Kind of Diabetes by each one with some different characteristics. As result
we today can see some Type 2 Patients with Insulin Therapies as before only at Type 1
has been applied and we can see for better Type 1 Management to achieve better
HbA1c or A1C %, by for example the Prolonged Metformin as Glucophage SR or XR
of daily only 500 mg get also to Type 1 Patients prescribed by some Doctors for the
better Liver-Glucose Control and also to reduce the Type 1 possible Heart Problems
for like that to solve two aspects for better Patients Health. Today also more and
more Diabetes Patients apply some Therapies Supplementations as for example
Vitamin-D, Vitamin-B12, Etc. much more as Therapy Support. The main breakthrough in
Diabetes Therapies will also come with the Artificial Pancreas by Insulin + Glucagon now
in developments with very good results as already seen and we possibly will see that
this will be applied for Any Types of Diabetes ! This maybe even combined with the
Peptide-C as a Triple- Pump System, which the body is producing in the same amount
as the Insulin and it has also a function in the body.
Because Subcutaneous in the Tissue, these Systems have an Effect-Delay of 25 – 30
Minutes for the Measuring about 10 Min. plus about 15 Min. for the injected Insulin
starting to have an effect to reach the peak within additional 30 – 60 Minutes.
( They try by Smart- Programming to compensate the Delay, but could Never Really
as good as any Direct- Drive Real-Time Intravenous System can do by without such
Programs just simply using a Hysteresis to set. )
The big breakthrough will be by some Intravenous Pump System which In Real Time
could function just in the same way as The Natural Pancreas. A Swiss Company is
presently working on this for at first for Clinical-Applications, for afterwards to be
produced for the worlds public market, by injecting and measuring all intravenously.
The Simple Therapy Rules For At Any Diabetes Types To Apply:
1. Fasting Glucose Value before or after any Meals 80 - 100 mg/dl !
2. During any Meals Glucose Above 100 mg/dl for Max. 2 ½ Hours !
( By This Your A1C Will Improve. )
Here the Scientists about Typ 1 Diabetics Heart Disease:
http://thediabeticnews.com/type-2-diabetes-drug-may-slow-heart-disease-for-type-1-diabetics/
15. Beta-Cells Transplants or Beta-Cells-Therapies or Immune Therapies To Cure Type 1 ?
Presently they last only 1 - 2 Years by the Body’s Autoimmune Reactions Ongoing.
The main obstacle is The Ongoing Autoimmune Reaction where also Medications
to suppress the Immune System with huge side-effects cannot really eliminate this.
It would need an Immune-Therapy able by formatting to re-orientate the Immune
System, but until today all Mono-Immune-Therapies did fail and so it maybe need
some Multi-Immune-Therapies to eliminate and stop the Ongoing Autoimmune
Reactions before any Cells-Transplants could become permanently successful,
or Gene-Technologically Modified Beta-Cells which could resist The
Autoimmune Reactions would be a second opportunity !
If the Autoimmune Reaction could been stopped, in many cases the
Pancreas itself could recuperate and get back to normal function.
Without This Pre-Conditions Fulfilled There Are No Chances For This !!
Here a New Way of Immune Therapy by Instead of Suppressing, Boosting The Immune
System By Certain T-Cells To Re-Orientate It, Which Looks More Successfully At Human
Trials, but it's not yet ready to increase the Beta-Cells Amount or the Peptide-C !!
https://www.ucsf.edu/news/2015/11/328176/immunotherapy-type-1-diabetes-deemed-safe-first-us-trial
Here a New Stem-Cell Immunotherapy
By Mice Trial – But maybe at Humans also successful !
http://stm.sciencemag.org/content/9/416/eaam7543
https://health.economictimes.indiatimes.com/news/diagnostics/stem-cell-therapy-used-to-reverse-diabetes/61674465
16. Doctors Symptoms List - For The 3 Months Consultations
This every Diabetes Patients should do to take with them when they meet the Doctor
at the Standard 3 Months Consultations for A1C or HbA1c, Etc. for Doctors to know
clearly at which Topics they may also have to concentrate on and find solutions for !!
This since Diabetes is generally not so stabile but some very individual ongoing
kind of condition.
This means for the Patients to observe themselves and Write On That List any kind of
Changes or Symptoms may occur, as also the Fasting Glucose Changed or The Feet’s feeling
Colder when compare the Temperatures By Hands or its Color tend to Turn Reddish or are
Swollen as not before or more often some Head Pain, Etc., just anything may changed or
did not experience before. ( Here Also Some Blood Circulation Disorder Symptoms. )
This for in addition to the Daily Glucose Measuring List, for the Doctors being able Just
In Time to possibly adjust or alter The Individual Therapies to avoid any additional
affections may possible !! !!
17. Healthy Nutrition Opportunity & Supplements
This if you like to reduce weight or to achieve or preserve the Ideal-Normal-Bodyweight
or like to Eat Healthy To Look Good, without any negative Side-Effects.
For this here a Protein Rich Diet without any Vitamins- or Minerals- Deficiencies, ideal for Type 2 Diabetics or People to remain healthy.
Starting by what is the Ideal-Normal-Bodyweight really and explaining this by some
simple system. Take the Inches above 40 (1m) and calculate with the remaining
inches above by for example calculate per each additional Inch (2.54cm) = 4.65 lbs (2.11kg)
this for Women with smaller skeleton and for Women with wider skeleton to add 6 % and for
Men with smaller skeleton to add 11 % and for Men with wider skeleton to add 18 % of lbs.
In Nutrition and especially at any Diets, it’s always important to have also
the necessary right amount of good protein, where too much is also not
good in general, where too much is creating increased urine in the blood
and this increases the risks of arthritis, etc., and not enough could create
complications as by women’s getting interruptions into monthly menstrual
cycles by possibly instead monthly just every 2nd or 3rd month or even
none of any, what is not good for any normal conditions in general.
Therefore the Right Amount and Good Quality of Protein should been
taken by One Egg-White per 22lbs (10kg) of Ideal-Bodyweight and by
Egg-White we have the Cheapest and Best Natural Protein to think of.
This is easy to apply once daily by taking the right amounts of Egg-Whites
to put into the Blender add 11 onzes Water and a Teaspoon Margarine with
Two Teaspoon Egg-Yolk and some Avocado or Strawberry, etc. any Fruits for
taste and mix it to get a very tasty healthy Shake Drink. This allows you the
Whole Day just to eat any kinds of Vegetables, Potatoes, Beans, Oatmeal, Salads
( Bread, Noodles, Rice only reduced. ), Etc., this as without any Meats, because the
right amount of Protein you need you have already by your Egg-Whites Drink as
in Best Quality and Superior Healthy, also for nice Skin and against Cellulites !
This is also important for any such who Digest Superior, or when
Older and therefore have problems to keep the Ideal-Bodyweight.
About Nutrition Supplementations
Some People or Doctors say, just a healthy nutrition is all it need, or applying
standard Vitamins & Minerals Blood Tests and if there is a Reference Amount
Deficiency shown of some Substances, then discuss this with your Doctor to
possibly using some supplementations for any corrections or completions.
That sounds perfectly, if there would not been the problem with these Blood
Tests since they’re made for Normal Healthy Humans, but Diabetics as known
have not Normal Conditions By It’s Metabolic Problems and beside some of
the Medications can also create certain deficiencies and at some Vitamins
or Minerals Diabetics by its Metabolism- or Biological- Disorders resulting
have higher demands which not so easy and sure could be compensated
by any nutrition ! ! !
Today’s Nutrition Quality is not anymore the same as 50 Years Ago,
because in the Industrialized So-Called Civilized World, the SOIL is not
anymore the same by the Acid-Sauer-Rain about 50% of the important
Minerals as Zinc, Potassium, Etc. got ALL Washed-Out or Neutralized !!
The international Nutrition Scientists since over 20 Years warning and
complaining about, but the Medical Society just ignoring The Reality
and telling everybody that a normal good nutrition is all it need, but
Today How Is It Possible To Have Again The Normal Nutrition ? ? ?
Therefore as following for Diabetics to consider :
Generally do not take Multi- Vitamins & Minerals Products containing any Iron or
Iodine and better just take certain Vitamins & Minerals by individual products but
in good qualities.
As Diabetic do avoid any Supplements with Iron or Iodine Concentrates,
because they Increase Glucose, the Diabetic Metabolism cannot handle
this Extracts anymore, therefore if you need Iron eat Beans or Celery
and if you need Iodine take Sea-Salt instead or use at any cooking.
The Multi- Vitamins & Minerals Products usually have also too many
different Substances combined with too many chemical interactions
resulting between them which partially are neutralizing each others.
Potassium ( Kalium ) Very Important !!
It’s upfront because it’s one of The Most Important Supplement
Mineral Especially For Diabetics but also for Normal People !
Without Potassium or Too Low, there is No Heart Beat ! ! !
Also Without sufficient Potassium the Body cannot store Glucose in the Muscles
for any quick release when needed and transforms Glucose it into Fat instead !
-- It is very important to maintain and preserve the Normal Potassium Level
of 3.6 – 5.2 mmol/L, but at Diabetics for safety 4.3 – 5.0 mmol/L as in the
upper halve for some reserves and to ensure that the Potassium Storage is
full as necessary. The Potassium Blood Test does not show Total-Potassium
stored in the body as necessary and the Blood Test should never show a
Potassium Level higher 7 mmol/L for also not getting No Heart Beat ! !
If there is No Kidney or Liver Problem, it would not be possible to have
it too high, because The Body by quickly urinating is well regulating it !
See Mayo Clinic Link https://www.mayoclinic.org/symptoms/low-potassium/basics/definition/sym-20050632
-- Diabetics should monthly test the Potassium Level ! If the body temperature
has not the normally 36.5°C but only 35.5°C it could be caused by the Potassium
Level too low to aware and/or the Thyroid function low also to check.
-- Diabetics to maintain the right Potassium Level and to make sure, should daily
eat 2 Bananas ( Middle Size Banana 450 mg Potassium ) or take Daily One Novartis
Slow-K® 600 mg Potassium Tablet and every Second Day Two Tablets, together
with normal Meals containing Vegetables.
( If experience some Hypo by the Rapid-Insulin of 60 mg/dl take immediately 1 Slow-K Tablet
extra and if even any Hypo of 50 mg/dl take immediately 2 Slow-K Tablets extra combined
with the usual Sugar amounts to increase the Glucose ! )
About the Potassium function. Potassium can be quickly released combined with
Adrenalin at Alarming condition, but the storage is a slow process. This can been
seen at any Extreme Hypo caused by wrong measurement where Rapid-Insulin got
injected for Glucose 300 mg/dl instead some Sugar taken at effectively 55 mg/dl.
When the Insulin-Effect kicks in it’s already too late and the body get flushed
by Adrenalin and Potassium with as result only 10 minutes later additionally
a Potassium-Hypo gets created, by the Blood Pressure and Heart Pulse goes
drastically down and the body temperature also, difficult to remain conscious.
In such a situation before falling in a KOMA, only 911 Ambulance can help
because Sugar not really functioning just reducing the KOMA-Risk and they
will quickly give some intravenous Potassium to transport into the Intensive
Care Hospital for there to receive 24 Hours Potassium Infusion to restore
the Bodies Potassium Storage !
As seen in the publications, the international Nutrition-Scientists agree that an
Adult Human from its daily Food Intake should have Daily 4000 mg Potassium,
but strongly mention that this usually is not achieved and therefore a complex
worldwide Study will be made.
See Here at NIH.Gov:
https://ods.od.nih.gov/pubs/2015_DGAC_Scientific_Report_ODS_Compiled_DS_Statements.pdf#search=%22potassium%22
Generally About Potassium https://medlineplus.gov/potassium.html
Hypokalemia https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357351/
Low Potassium Level https://medlineplus.gov/ency/article/000479.htm
Potassium In Diet https://medlineplus.gov/ency/article/002413.htm
Potassium Test https://medlineplus.gov/ency/article/003484.htm
By today’s Foods or Diets or Medications there is a worldwide
deficiency of Potassium, Zinc, B12, etc., as Risks of Diabetes.
See the Studies in the Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197792/
Potassium can also reduce the Effects of Diabetes and Improving A1C Values !!
Important Potassium Information
WDHCO became to know that Potassium is reducing the Insulin Resistance
and Disease Progression. At some Patients with a Rapid- Insulin Glucose
Reduction Factor of only 10 - 20 mg/dl per Unit, under Potassium of daily
900 - 1000 mg it became a Units Reduction by about 40 mg/dl per Unit !
Basal-Insulin from daily 18 - 20 Units, over 5 months got reduced to daily 6 - 8 Units only
by the A1C of very normal healthy 5.0 - 5.2 % preserved !
From too high blood pressure of DIA 80 and SIS 160 with Pulse 70 - 75, within
4 months of supplementing daily 1000 mg Potassium, the blood pressure got
back to the patient’s normal of DIA 65 - 70 and SIS 110 - 120 by Pulse 60 - 65 !
( The normal individual Reduction Factor per Insulin Unit at T1D is in the range of
30 - 50 mg/dl, at Type 2 with its Insulin Resistance in the range of 1 - 20 mg/dl. )
Under this Reality it’s really surprising that Potassium is not part of any
Standard Medications at any Diabetes Types Therapies, also to Reduce
Heart Failure Risks !!
According laboratory blood tests at people without any Liver or Kidney
problems ; by daily eating Potassium rich meals with Potatoes and Beans
and additionally by Supplement take daily 1000 mg Potassium, will ideally
result to 4.3 – 4.6 mmol/L Potassium in the blood as a little above the
normal middle- value for a good enough reserve.
The normal reference value is 3.6 – 5.2 mmol/L, where the middle of
optimal minimum is 4.4 mmol/L and 3.6 mmol/L is already causing
reductions of Heart Functionality ( Increased Blood Pressure, Etc. )
and reduced Glycemic- Regulation ( Increased Glucose ) to know well !
This reconfirms the international scientists publishing, that the world
population have some daily deficiency of about 1000 mg Potassium !
Have also a look at Topic 30. about Heart & Health !!
Vitamin-B12
Preferable in the form as 1st and best Hydroxyl-Cobalamin or 2nd Chloride-Cobalamin.
Never use the cheapest common Cyano-Cobalamin, because Cyano is toxic
and therefore neutralizing the positive effects of Cobalamin-B12 !
The usually recommended Dose of B12 is daily 2.5 mcg, nearly useless, because
to be effective For Diabetics but also any Normal People it needs daily 30 mcg
and there we are at beginning of recommended medical dosing it really need.
The daily B12 30 mcg also protects the lungs and also important for smokers.
B12 in the nutrition-chain is a very seldom substance and therefore it’s nearly
impossible by normal meals to get enough from and Vitamins should never
been heated to higher 45°C or 113°F !!
B12 is one of most important Vitamin related to many essential biological
functions as can be seen at following NIH.Gov Link and B12 get reduced by
any Metformin Medications as typically applied at Diabetic Type 2 Patients
and B12 is also strengthening the immune system and improves healings of
wounds, something important where Diabetics often have healing problems.
Regrettably it’s a little difficult to get B12 by the right quality at commercial
products.
The best is you know a good pharmacy you also have a good relation with
and order to do some 1dl Distilled Water Solution by 5 mcg B12 per Drop,
where you take 6 Drops for Daily 30 mcg and this by using for the Solution
liquid Injection-Ampoules of Hydroxyl-Cobalamin as the best quality or as
second best Chloride-Cobalamin, to keep in the refrigerator above freezing
temperatures. It will not be so expensive, but maybe because made by the
medical quality you may need a Doctor’s prescription, that joke but . . . .
Here the NIH.Gov Link to know about : https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/
Vitamin-D3
In the form of Cholecalciferol.
This is also a Vitamin not easy to get by any meals, because it’s principally
synthesized within the body under the skin by the sunlight, but by Diabetics
or Older People the synthesizing process is not functioning as it used to be
where the demand is even increasing. At Diabetics generally D3 is at lowest
of normal or below, where it needs more for immune system and hormones
production and many more biological functions in the body as seen at Link !
Also here the Daily Dose should be 15 mcg or 600 IU and this is already in
the beginning of medical dosing. To be effective buy any Liquid Product !!
Here the NIH.Gov Link to know about : https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
Zinc
In the bioactive Zinc-Gluconate Form take daily 5 mg and never buy
any cheap but useless Zinc-Oxide Form.
It’s good in general for the Metabolism and Immune System Strengthening !
There is a worldwide Zinc deficiency in the populations.
Here the Pauling Institute to know about : http://lpi.oregonstate.edu/mic/minerals/zinc
Manganese
In the bioactive Manganese-Gluconate Form take daily 2.5 mg and never buy
any cheap but useless Manganese-Oxide Form.
I’ts Metabolism Harmonizing and reducing Glucose Level Tolerances !
Here the Pauling Institute to know about : http://lpi.oregonstate.edu/mic/minerals/manganese
Boron
In Liquid Distilled-Water Made From Boric-Acid At Concentration of 1.6 w%,
Adults to take Daily 2x 5 Drops morning evening resulting to about 12 mg !
This any Pharmacy cheap can produce for you, for storage at refrigerator
Above Freezing Points temperature.
Boron is also the general natural hormones building motivator for the
body to produce enough from and this especially also when older to
bring back the hormone levels to where they used to be and it means
such as Menopause Symptoms by Women’s or Men’s can be eliminated
and is also against Arthritis or Osteoporoses, Etc.
Boron has such Multiple Advantages and Metabolic Importance’s, that
Everything to mention would been too much here and therefore you
should to take the time to go through the NIH.Gov Link here : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712861/
Chromium
In the form of Chrome-Yeast is the best followed by Chrome-Glukonate as
bioactive to be biologically useful to take Daily 40 mcg. Chrome is also useful
to reduce Glucose and together with Niacin-Vitamin B3 are essential to form
the GTF - Glucose Tolerance Factor and for Metabolic Harmonization’s, Etc.
Here the NIH.Gov Link to know about : https://ods.od.nih.gov/factsheets/Chromium-HealthProfessional/
Niacin-Amid & Niacin-Acid
Vitamin-B3-Amid in the body get reduced to the bioactive B3 Niacin-Acid Form,
for Niacin-Amid Daily to take 100 mg.
Where the Niacin-Acid could create reddish-skin, flushes, itching and Increases
Glucose at higher Doses, Niacin-Amid does not doing this and is safe to take.
Together with Chromium, B3 is essential for the GTF - Glucose Tolerance Factor
and to reduce the Blood Fatty-Lipoids Triglycerides by reducing the Bad LDL-
Cholesterol and to increase the Good HDL- Cholesterol, many more Functions.
Here the NIH.Gov Links to know about : https://medlineplus.gov/druginfo/natural/924.html
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757682/
To improve Blood-Circulation by opening the Veins or at Neuropathies take Slow
Prolonged Niacin-Acid 3x daily 125 mg !
( This by its 125 mg dosing will not create reddish-skin, flushes, itching and will
not increase the Glucose. )
Upsher Smith Laboratories has one called “SLO NIACIN” 250 mg dividable for 3x 125 mg.
Vitamin-B Complex
In addition to above Vitamin-B3-Amid to take a good Vitamin-B Complex, but
Daily only 1/2 of any recommended Dosing, it is important for any metabolic
Fuctions where Diabetics have problems with.
Here the NIH.Gov Link to know about : https://medlineplus.gov/bvitamins.html
Selenium
The best source of Selenium is Selenium-Yeast because it mimics the natural Selenium
Source of such as Tuna-Fish where 100 g contain 100 mcg of Selenium.
The problem with Selenium is to get Pure Selenium-Yeast not mixed with any Magnesium
Stearate as for example clumsy in the US at most products in powder form is applied
and this where The Neutral Micro-Crystalline Cellulose could do the same just to
keep powders flowing at Capsules producing machines.
Magnesium has a chemical interaction with Selenium where it get nearly neutralized
and losing it’s bio-effectiveness, therefore never any Magnesium combined with !!
You need to find a Pure Selenium-Yeast product with additives by Micro-Crystalline
Cellulose and/or Shellack for Tablets hardening, to be bio-effective ! ! !
Take Every Second Day 350 mcg Selenium for the metabolism not getting a custom
to it to remain effective and take it 2 Hours apart from any other Substances
because Selenium as very sensitive get affected by about anything and just
at any temporary Acute-Inflammation conditions for not more than 8 Days
you could take it daily at 350 mcg as the well experienced max. Dose !!
The Selenium Effect last for about 26 Hours Without Any Negative Side-Effects !
By the Effect of Selenium not only Bacteria’s get eliminated,
but Viruses also, something Antibiotics cannot, because only
eliminates some specific Bacteria’s by specific Antibiotic !! !!
Selenium as essential is definitive strengthening boosting the Immune System
and this is very important for Diabetics which often experience Infections or
Inflammations by the weakened Immune System.
The Selenium is very well known for its huge Inflammation- or Infects- Reducing properties
and resulting is also reducing and eliminating Diabetic Pain !!
It together with Vitamin-E and Aspirin as here explained could play a key role
as prevention or to fight any kind of Diabetic Neuro-, Retina-, Etc.- Phaties !
People should also more carefully study the life of People in Okinawa Island where
they eat Tuna at a regular daily base and at its Monthly Marathon of 10 Miles
they have even some already 100 Years old and still regularly participating at
or such of 110 everyday working at it’s small gardens happily.
Here the NIH.Gov Link to know about : https://ods.od.nih.gov/factsheets/Selenium-HealthProfessional/
At Acute Neuropathies reduce the A1C to Average Glucose of Max. 97 mg/dl
and take Every Second Day the 350 mcg Selenium as above, but in-between take
also only 250 mcg Selenium to strengthen- and preserving- its Effect.
Selenium to preserve its Effect need to be taken 2 hours apart from any other
Medications or Substances or Supplements.
By this in combination with the Aspirin every second day and daily Vitamin-E 600 - 800 mg
plus Vitamin-B12 daily 30 mcg, B6 10 mg and 3x daily Slow Niacin 125 mg ( B3 ) it’s possible
to recover within 1 - 2 Years by the Feelings also returning again.
( For example Alpha Lipoic Acid provides too little recovery if any and is not solving the problems. )
Vitamin-E
There it would be important to have the Natural Vitamin-E Complex of at
least the 4 Tocopherols https://en.wikipedia.org/wiki/Tocopherol and the
best would be with also the 4 Tocotrienols https://en.wikipedia.org/wiki/Tocotrienol
to have the Complete Complex As In Nature.
It is known that principally Vitamin-E is providing its advantages only by
the Complex, but to get the Complete Complex by the 8 Different once
is not easy to get in the market.
Therefore as easy to get Complex by the Natural 4 Tocopherols is mentioned
the product as from VitaminShoppe, Item No. VS-1551 200 IU Softgel-Capsules,
or any other supplier with the same product quality.
Take Daily 600 - 800 IU as Prevention or Reduction of the known Blood Circulation
Disorders Diabetics experiencing by the higher Glucose Values where the Blood
Bodies stick together and resulting causing it combined with Inflammations or
Swollen and/or Reddish Feet !
Vitamin-E as known by the Red-Blood-Bodies is keeping them separated and
like this the Blood get better higher flow characteristics or improved flowability,
but before of any Operations the intake must 48 Hours before been stopped
for not having increased bleedings ! ! !
Here the NIH.Gov Link to know about : https://ods.od.nih.gov/factsheets/VitaminE-HealthProfessional/
Aspirin
As known by the White-Blood-Bodies is keeping them separated and like
this the Blood get some better higher flow characteristics, but before of
any Operations the intake 10 Days before must been stopped for
not having increased bleedings ! ! !
The White-Blood-Bodies when getting once in contact with the Aspirin
Substance, losing its interconnecting ability important at any wounds
healing to stop the bleedings and it takes 7-8 Days for all the White-
Bodies to renew again and therefore Aspirin should never been taken
at a regular daily base to Increase The Blood Flow Characteristics !!
In combination with Vitamin-E and Selenium; therefore take it just every
2-3 Days, means taking it and Pause for 1 - 2 Days then take it again,
etc., this as compromise to reduce any Risks of internal bleedings by just
using it’s advantages. This by preserving enough of the White-Blood-Bodies
ability at any Wounds-Healing and providing enough Improved Blood Flow-Ability !
Here the NIH.Gov Link to know about : https://pubchem.ncbi.nlm.nih.gov/compound/aspirin#section=Absorption-Distribution-and-Excretion
If like to take Aspirin regularly as a Vascular- and Blood Circulation-
Supporting Precaution, it should never been taken at a daily base to avoid
Substance- and Effects- Accumulations resulting to possible uncontrolled
internal bleedings anywhere in the body. Therefore and to have only the
advantages of Aspirin it is proposed to take it by ½ Standard Tablet
Every Second- Day by One Day Pause to preserve only the Advantages
of Aspirin. Regularly, Never Take It Daily !!
The Aspirin related to Blood- Dilution cannot really been Doses controlled
and this means even the Baby- or Cardio- Aspirin daily taken can cause
internal uncontrolled bleedings, because the White- Blood bodies need to
get only in contact with the Substance to lose its Interconnecting- Ability !
Maybe you get this Science Based Information here the first time, but when
discussed with any Doctors, everyone will confirm this as the smart- way to
handle Aspirin.
Special Attention !
If your Excrements under the Aspirin turns very dark to nearly Black-color,
instead of Braun-coloration, then you should apply an intake-pause of 2-3
Days instead of 1 Day only by the possible internal-bleedings of intestine’s.
If changing the intake pause to 2-3 Days does not help to get Excrements
Braun-color, then stop the Aspirin intake.
If you already apply some medications to dilute the blood then you should
additionally not use any Aspirin and if under the use of such medications
Excrements of nearly Black-color do exist, then you would need to contact
your Doctor to stop the medication and also have Blood Hemogram Tests
every 6 Months made to analyze if there is any Blood-Anemia !
The Apirin intake stopping 10 Days before of any Surgeries is the
medical standard.
Aspirin, Vitamin-E, Slow-Niacin-Acid for Diabetics of Any Ages Required !! !!
18. Drinking Alcohol and Diabetes
Generally Medications and Alcohol is not a good combination and for
example by Metformin the alcohol effect is increased and so possible
Diabetic complications. A Glass of Wine or Beer is OK but not more !!
At Diabetics using Insulin-Therapies we need to apply preconditions
if it’s not just a glass of Wine or Beer and turns-out more like to
be a drinking session with friends as the worst case.
The Liver occupied with the Alcohol cannot anymore supply the body
with Glucose as it usually does so well and resulting much less and
not enough Glucose is available and the Glucose-Level is going down
into Hypos when not parallel to the drinking also any food is eaten
to compensate the lack of Liver-Glucose and the usual Hypo Signs
under Alcohol cannot been realized anymore and therefore it need
someone nearby to check your Glucose to provide you any Carbon
Hydrates when necessary !! !!
You have to imagine and keep in mind, that by eating the carbon
hydrates at digestion will go directly into the blood independent of
the Liver-Conditions and you have to keep in mind, that emergency
Glucagon injection’s to promote the Liver to release Glucose under
Alcoholic Conditions will possibly not work ! It gets Dangerous !!
The Alcoholic Effect last longer where the most critical conditions
will be 3 – 6 Hours after drinking where the Potential For Hypos
is the greatest because the Liver will need more time to get back
to its normal functions, possibly your Basal-Insulin is also working
to make it worse and that means at middle in the night after the
drinking it gets the most dangerous and someone should be nearby
to watch and measure the Glucose to intervene with Sugar-Water
drinking in up-right position as long as any drinking is possible.
When the Sugar-Water drinking gets difficult and the speaking get
difficult Call 911 Emergency and until its arrival by a Teaspoon in
up-right position put Sugar-Water in the Mouth and that will go
down to digest and like that the Glucose-Level can also be lifted
or at least not lowering any more to stay-out of any coma-risks.
If a Person is alone in such conditions and has nobody to help,
it could Die to be aware of !!
The emergency team needs to be qualified for such Extreme Hypo
conditions. That means by the standard procedure if the Glucose
is still too low, that Intravenous Glucose gets slowly injected and
the lost Potassium important for the Heartbeat by Intravenous
Potassium slowly injected get quickly supplemented and the patient
connected to a Glucose & Potassium Infusion to be transported
to the hospital Emergency Room.
For such Situations prepare 8 oz or 2 dl of Sugar-Water made by 4 Heaped
Teaspoon of Sugar put into Warm-Water and stirred until it becomes clear
again to keep beside the bed for any emergency to drink. This will increase
the Glucose by about 110 mg/dl within 30 Minutes and when may necessary
to prepare more !
( If the person is also using Glucobay Medication, then instead any
normal sugar, it needs Dextrose ( Fruit-Sugar ) to be effective !! )
At Alcohol drinking sessions there are some Rules, Do Not Inject
any Basal-Insulin, because that by its long-term-effect will make it
after more difficult and at any eating do not apply any Insulin for
that moment and this independent of how high the Glucose may
will go, because its better and more safe under that conditions
to keep the Glucose higher for after to have less lowering and if
possible to stay away from any Hypo may 40-50 mg/dl and try to
keeping it above 100 mg/dl and this also by keeping eating !! !! !!
Here one more Link about this topic: https://health.usnews.com/health-care/patient-advice/articles/2017-09-28/is-it-ok-to-drink-when-you-have-diabetes
19. Diabetics Erection Disorders
This Must Not Be. If the A1C is in the Range of 5 % or Average Glucose 91 - 103 mg/dl
as by the Healthy People, then there is no physical reason why that should be, because
there would not be any Blood-Circulation-Disorders and other reasons as also possible
by Healthy People are the real cause, such as Mentally or possible Not Enough
Testosterone-Hormone especially by Men’s above 30 Years of Age !!
As a Men and within the healthy Average Glucose Range as above described and
when in the early morning hours at sleeping or just wakeup, has not at least a
Half- or Full- Erection as very natural by Men’s, then it means that there is Not
Enough Testosterone and for this should contact the Doctor for by Blood-Test
testing it and ask the Doctor for some Testosterone Tablets to prescribe, maybe
temporarily also combined with Viagra and applying Products To Improve Blood-
Circulations such as every 3 Days some Aspirin with Daily 600 - 800 mg natural
Vitamin-E ! A Boron Supplement of daily 3x 5 mg can also help to increase the
Men's Testosterone Level to normalize.
Usually Erection Disorders are not just caused by one factor alone, but have
Multi-Factors in play, such as what is Attracting, what kind of Desires may not
Fulfilled and it’s necessary to concentrate on what is providing the Right Kick
May Need or have Interests For and find the right solutions for this in reality
to have also a happy sexual life too and not just a nice monthly income !!
For General Erection Disorders, not only to Diabetes related, it’s preferable
to take Daily 2x Cialis 5mg every 12 Hours. The Halve-Lifetime of Cialis
is 17 Hours and therefore it makes sense to take that small dose every 12h.
This in reality shows a good enough erection, but only once daily the 5mg
as informed is usually not enough medical support to know well !
20. Misdiagnosed Diabetes Type 3c
This is not to blame Doctors where under the present Situations are much more
Diabetes Patients and not enough Qualified Professionals are available and where
it is very individually or complex.
The Type 3c Diabetes diagnosed as Type 2, this happens often and where today
statistically this Type occurs even more often as Type 1 Diabetes.
Type 3c Diabetes mainly caused by Pancreatitis Inflammations where the Pancreas
resulting is not producing enough Insulin and resulting Hyperglycemia occurs and
where instead immediate Insulin-Therapy just getting the typical Type 2 Medication
such as Metformin can be fatal for the Pancreas and the Patients health.
This has also to do with the applied Standard Tests and where not all possible
Tests are Standardized.
For Example :
- OGTT Tests will not show the difference between Type 1, Type 2 or Type 3c,
if after two hours the Glucose is not below 200 mg/dl just Diabetes is defined,
but not which Types !
- If a HbA1c or A1C Test is made and 6.5 % or higher it confirms Diabetes and
when 5.7 % or higher it confirms Pre-Diabetes, but not which Types !
- If the Morning Fasting Glucose Tests show less 99 mg/dl it’s interpreted as healthy,
But Possibly Not and if it shows 100 - 125mg/dl its defined as Pre-Diabetes and
at 126 mg/dl or higher is Diabetes defined, but it does not definitely confirming
which of the Types or really Healthy !
- If Peptide-C Tests made they would show if the Pancreas is producing enough
Insulin or not enough or too much Insulin and by this provide some direction to
decide which Types may possible, but since there are no Standards of How To
Do this Test under which None Existing Standard Pre-Conditions, it has a poor
evidence, because when for example made by Blood Glucose of 70 mg/dl all
Patients will not produce enough Insulin, because at Glucose of 70 mg/dl there
is no need for Insulin but possibly for Glucagon to avoid any Hypoglycemias !
- Autoimmune Antibody Tests to prove Type 1 or LADA Type, but this test will
not prove Type 3c or Type 1 with Type 2 as by the AAN Type.
( Here to make it simple we have to keep in mind, that for example Type 1 is
not producing enough Insulin and resulting has Hyperglycemias and Type 2 is
generally producing Too Much Insulin but because of Insulin-Resistance where
the Insulin cannot show the Effect has resulting Hyperglycemias. Hyperglycemias
by the Two Different Characteristics caused and by Type 3 the Pancreas maybe
producing still enough Insulin to keep healthy Fasting Glucose Levels only, but
not producing enough for at Meals and therefore causing Hyperglycemias !
A Mix of Type 1 with Type 2 is also possible and even LADA without any
Autoimmune Antibodies as by the AAN Type is also possible. )
To Really Differentiate Some Diabetes Types Exist Test Procedures,
but these are regrettably None Standardized Once, as following:
-- The Insulin Resistance Test. Keep the Patients at Glucose 180 - 200 mg/dl
for example with Reis and apply 3 Units Rapid-Insulin and measure Glucose
after 2 Hours.
If per Unit Rapid-Insulin there is a Glucose Reduction of 30 - 60 mg/dl per
Unit there is No Insulin Resistance just individual efficiency differences.
If per Unit Rapid-Insulin there is a Glucose Reduction of Less 20 mg/dl
then there is typical Type 2 Insulin Resistance proven.
Repeating this Test 3x and if at least 2 Results confirm the same the
Test can be used as Reference !
To avoid any Hypoglycemic Risks during the Test, liquid Sugar to drink
should been prepared.
By this Test can clearly been differentiated between typical Types 1 or
Types 2, but it remains an opportunity of Type 1 with Type 2 Mix !
-- Peptid-C Test Under Glucose Load of 140 - 160 mg/dl to show the
maximum possible Insulin Production of the Pancreas !!
The Pancreas at over 100 mg/dl getting forced to produce as much
Insulin as it can and by that shows its maximum capacity.
By this any Type 1 Characteristic could never reach the Normal Maximum
and it would also show to at which % the Pancreas may still functioning.
By this any Type 2 would show even more than the Normal Maximum
and this could been taken as a clear Proof of Type 2.
-- By combining the Results from above Insulin Resistance Test and the
Peptid-C Test Under Glucose Load, the Type 1 or Type 2 or Type 3c or
Type 1 with Type 2 or Type AAN- Autoimmune-Antibody-Negative with the
Reactive-T-Cells, by Proof could all been differentiated and evaluated !
( ADA As World Reference For Diabetes, where are The Diabetic Standardized
Test Procedures Necessary to cooperate with The World Diabetes Epidemic ? )
Here More From NIH.Gov About Type 3c Diabetes:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003514/
https://www.niddk.nih.gov/health-information/digestive-diseases/pancreatitis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045545/
As a Scientist of a well known Big Pharma Company once mentioned:
Medicine is a Kind of Art regrettably not more Physically Based, where
even The Doctors Individuality and Attitudes are considered to respect,
but now we need The More Physically to handle the Ongoing Epidemic !
21. Gene Mutation Causes New MODY Diabetes
European and Japanese Scientists did find a new type of Diabetes caused
by mutation in the Gene RFX6 which offers a possibility of 80 % for within
25 - 50 Years to develop the Disease.
It means Gene Sequencing Screening makes sense to know before !
See here the Link: https://www.nature.com/articles/s41467-017-00895-9
22. UKs Top 10 Priorities For Type 2
Its principally something which already long ago should have been done,
but it’s sure better now than never.
See here from Oxford University: https://www.phc.ox.ac.uk/news/top-ten-research-priorities-for-type-2-diabetes
23. Smart Synthetic Beta-Cells Insulin T1D & T2D Patches Treatments ?
At Mice’s it looks successful, but has to prove the same at Humans.
See Here For T1D: http://news.unchealthcare.org/news/2017/october/smart-artificial-beta-cells-could-lead-to-new-diabetes-treatment
http://news.unchealthcare.org/news/2015/june/smart-insulin-patch-could-replace-painful-injections-for-diabetes
Supplementary Information: https://images.nature.com/original/nature-assets/nchembio/journal/vaop/ncurrent/extref/nchembio.2511-S1.pdf
See Here For T2D: https://www.nibib.nih.gov/news-events/newsroom/pain-free-skin-patch-responds-sugar-levels-management-type-2-diabetes
https://www.nature.com/articles/s41467-017-01764-1
24. The Brain Also Produces Insulin
This is not surprising considering that the Brain produces many different kinds of
essential Hormones and where as known any Nutrients, Vitamins, Minerals and
Hormones can pass the Brain’s Blood Barrier !
In contrast to some interpretations, Insulin has also an important role in the Brain
to function as seen in the following NIH.Gov Links.
In the following NIH.Gov Link read the Titles :
- Central origin of insulin
- Detection of C-peptide in the brain
- Detection of insulin mRNA in certain brain regions
- Experimental approaches with brain cell cultures
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191295/
Brain insulin: regulation, mechanisms of action and functions.
https://www.ncbi.nlm.nih.gov/pubmed/12701881/
Brain insulin, energy and glucose homeostasis; genes, environment and metabolic pathologies.
https://www.ncbi.nlm.nih.gov/pubmed/18407262/
25. Over Weight Problems & Type 2
If all Your attempts and intellectual Goodwill fails to reduce the Bodyweight to Normal
as also described here at Point 17. Healthy Nutrition Opportunity, then you possibly a
Superior Digesting Person by Your Genes and this by some Surgery should been
corrected to the Normal and let Your Belly- Fat at the same time remove to have
faster a good result also by one problem less for the future. For example the Native
Hawaiian People have the same problem by its Genes and therefore usually Type 2.
The best result is by a sleeve reducing the Stomach size combined with shortening
the Intestine to correct and adjust the Individual Genes Nature and at same time let
remove the huge Belly-Fat by drainage for within 3-6 years to be medication free and
this can easy been done by some specialists team.
( The removed Belly-Fat-Cells will not grow back where Belly-Fat causes problems. )
There are many Surgeons today with good experiences which could help You really
and You better do this sooner than too late for your general health conditions !!
New Study Finds Diabetes Under Control Without Insulin, 7 Years After Bariatric Surgery
https://www.prnewswire.com/news-releases/new-study-finds-diabetes-under-control-without-insulin-7-years-after-bariatric-surgery-300548433.html
If the Nose is not strait in the Face, usually get corrected and
if Genes not able to fit the Living it gets today also corrected.
Simply speaking, for example if a bird got double weight it loses
its nature, cannot fly anymore and resulting . . . . .
See Also Here:
There is increasing evidence that by helping speed weight loss, bariatric surgery
may be one of the most powerful tools in the fight against Type 2 diabetes for
people who are candidates. In fact, many patients who have the surgery no
longer need medication at all to control their diabetes.
“For people who are obese and dealing with Type 2 diabetes, the benefits of the
surgery usually far outweigh these risks,” said Dr. Tohamy. “The surgery can help in
the battle against obesity, which in turn helps to improve or eliminate your diabetes.”
“Bariatric surgery can be life-changing for the right person who is struggling with
excess weight and diabetes,” said Dr. Tohamy. “If you’ve tried and failed to manage
your weight and disease through more traditional methods, talk to your doctor to
see if surgery could be a good fit for you.”
http://www.crozerkeystone.org/news/press-releases/2017/november/can-bariatric-surgery-reverse-type-2-diabetes/
26. Nov. 2017 Study Report - ADA Diabetics Fooling Masterpiece ?
By its Nov. 2017 Supplementary Report about Brain-Volumes Affections as seen
in the Below Links and PDF Tables, as attempt to reconfirm its Poor- Guidances.
As seen in the Report they just decided that A1C 5.7 % or Less is adequate
None Diabetes, but as seen in the PDF Table 3. They Have No References of
Real None Diabetics with A1C of 5 % to compare as necessary for Proof as
at any Reference Study made by International Studies Standards ! ( Hallo ADA ? )
Further they hypothesized, where frequently the wording “hypothesized” or
“hypothesis” is applied and therefore it need to be explain that a Hypothesis
is anything unproven just Like Fantasies, where in contrary Any Theory Is Proven
and therefore to be declared as Theory because by Scientific Evidences proven
and herewith is the difference between Hypothesis and Theory proven as any
Scientists would only confirm.
By hypothesizing in The Report they also mentioned that they could not find
any evidence that Vascular ( Brain’s Micro- Vascular Capillaries Netting ) causes
the Diabetics Brain Volume to become smaller and therefore speculative concluded
that it must be something else causing it.
( Any of the world leading Profs. Neurologists knows reduced blood circulation
causes low inflammations as caused by higher Blood-Glucose and that causes
Partial Brain Cells Dead resulting to Reduced Brain Volume. )
The Study is made by MRI-Tomography and the Brain-Volumes are calculated
by 3D-Software. MRI as known by anybody has a Resolution of max. 1 mm, but
the Micro- Vascular Capillaries Netting Veins have a Diameter of only 0.01 mm
( Diameter 1/100 mm, see the Link https://en.wikipedia.org/wiki/Capillary )
as 100x smaller than the MRI could find or see and with a Microscope as necessary
by Biopsies going into the Brain for Proof, that they did not do for not harming or
stressing the Participants.
( Brain- Tissue Samples Usually Taken From Dead People Or At Brain Surgeries. )
This ADA Study Is Not Made By The International Study Standards And
Not Considering The Existing State Of The Art Knowledge !!
The Report mentioned that more detailed Studies are necessary, as objectively
just one of the very few valuable info provided.
Here the ADA Study Report and PDF Tables Links:
Report http://care.diabetesjournals.org/content/40/11/1514
PDF Tables http://care.diabetesjournals.org/content/diacare/suppl/2017/09/12/dc17-1185.DC1/DC171185SupplementaryData.pdf
Luckily We Have The NIH.Gov by A1C higher 5 % ( Old 5.4 % ) or Average
Glucose higher 97 mg/dl, confirming Vascular Affections, see the Link:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911067/
NIH.Gov and Diabetes Brain Issues, Vascular Caused Brain Volume Reductions:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836136/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273865/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064119/
Here is the international Proof by the Link the ADA by it’s
attempts to increase the A1C’s, sure don’t likes !!
HbA1c – A1C Diabetes and Cognitive Decline
https://www.ncbi.nlm.nih.gov/pubmed/29368156
NIH.Gov As The World Reference In Medicine !
27. Nov. 30th - How Naïve To Reach Out To NIDDK !
Here below is the result to see if someone is trying to Cooperate or
Discuss with such as NIDDK, ADA, Etc., to help at Diabetic Epidemic !
https://www.niddk.nih.gov/health-information/professionals/diabetes-discoveries-practice/prediabetes-game-plan
Discussion on NIDDK 0 comments
Talking to your Patients about Prediabetes - Do You Have a Game Plan?
Comment Nov. 30, 2017 - Detected as spam. Thanks, we'll work on getting this corrected.
healthinfo@niddk.nih.gov
.
Dear NIDDK,
Since there nobody replied to you, we now reply.
We can be agree with everything of Dr. Ann Albright here.
At NIH.Gov are enough Studies to be considered and there is no need
for new Studies, except for new kind of therapies.
Its important for diabetics to get objective and reliable information and
for that purpose we established the WDHCO as here seen by the link:
http://worlddiabeteshealthcareorg.business.site/
1. It is troubling if the NIDDK is coming with ADA info as for Normal Healthy
People A1C of less 5.7% or Av. Glucose less 117 mg/dl where since over
40 Years its Av. Glucose less 100 mg/dl.
( New Norm A1C 5% or former 5.4% = Av. Glucose 97 mg/dl )
Here NIH.Gov Link compare to A1C of 5%, the 5.5% has already double Risks:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911067/
2. The NIDDK should enforce better A1C Laboratory Evaluation Standards.
Presently there is the Tolerance of plus-minus 12% or total 24% and this
where the Doctors and Diabetics should been able to relay on.
The Calibration Process of these Equipments need improvements !!
3. The NIDDK should achieve that the FDA has only one class “Diabetic
Controlling Medications” and not anymore the Type 1 and Type 2 System
where finally the Health Insurances deciding the therapies and possibly
not the Doctors.
Same as the Type 2 get some advantages from typical Type 1 Medication,
Type 1 can possibly also have some advantages from Type 2 Medications.
For any devices by FDA just the class “Diabetic Controlling Devises”.
This by simplicity to preserve the necessary therapies flexibilities.
Kind Regards,
Ch.R.– Founder of WDHCO
--------------------------------------------------------------
28. The ACCORD Study 2009 Should Never Been Made By Its Incomplete Conclusions,
but now By Joslin it gets warmed-up again to mislead !
http://www.joslin.org/news/Trial-Suggests-Way-to-Personalize-Heart-Health-in-Diabetes.html
Accord Study 2009 Fulltext http://www.ajconline.org/article/S0002-9149(07)00438-9/fulltext
The Study Facts As Following:
-- Only Type 2 Patients with CVD-Risks considered where as known Type 1 has the double CVD-Risks !
-- It’s the Study which tells compare A1C of 8 %, A1C of 7 % has 12 % less Amputations and how many % remain ?
This to confirm the convenient A1C less 7 % Rule !
-- For the CVD-Risks to evaluate applied 2 Groups, A1C less 8 % and less 6 % !
-- Where never more than 2 Factors or max. 3 should been taken for reference purposes, this Study
has nearly unlimited Factors in play and resulting about 10 more Studies should been made to clarify !
-- Here by every used Medication or kind of Nutrition the Factors shown: Treatment algorithms using Metformin,
Sulfonylureas, Meglitinides, Thiazolidinediones, α-Glucosidase Inhibitors, Insulin, and Insulin Analogues, coupled
with Lifestyle Intervention, have been developed for the 2 groups. Exenatide was added to the available formulary in
April 2007 ( See the Side-Effects of Each Medication by some even supporting CVDs ! ).
Normal Nutrition and for at A1C less 6 % also Low-Carb Nutrition to achieve !
By Low-Carb Nutrition is known that in the Digestive gets less GLP-1 Hormone produced and therefore it’s no surprise
that the Also Heart-Supporting Hormone is getting too low and that has been proven at this Study as the only Merit
and useful Fact ! ! !
-- Totally 13 Factors applied, where even any Super Computer could not handle more than 5 Factors with all it’s variables !!
-- The A1C less 6 % T2D Group, should have been treated with Metformin plus Basal- and Bolus- Insulin only and under
Normal Nutrition and the Result would have been the opposite by the normal GLP-1 and would have confirmed the NIH.Gov
Study Result of 2010 as seen by the Link here, where the IDEAL with lowest CVDs by A1C of 4.8 to 5.2 % or Average Glucose
91 - 103 mg/dl is proven by Non-Diabetics with Normal Nutrition ! https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911067/
-- This above proves the Medicine as Kind of Art, where any Physicists regret that it is not more physically based also by
more systematical methodologies !
Harvard Please Do Better Than That !
29. Diabetes and 30-40% Chronic Kidney Disease: an increasingly common multi-morbid disease
in need of a paradigm shift in care !
The Result of Micro-, Macro- Vascular Blood Circulation Disorders Caused By Too High A1Cs !
See Here: https://www.ncbi.nlm.nih.gov/pubmed/29247554
Right, It Need A Paradigm Shift In Care ! ! !
But Very Regrettably This Is Not Possible With ADA & Co. where they defend
only the convenient ways and to preserve the Diabetic Status also for in favor
of the Pharma- Industry !
ADA by Guidance’s like Glucose Range 80 - 180 mg/dl, or 80 - 120 mg/dl now
even increased to 80 - 130 mg/dl, with A1C at best less 7 % but prefer 8 %
instead of 5 % as for Healthy People for the Diabetics daily to apply and this
where between the Meals it should been Glucose 70 - 100 mg/dl and at Meals
above 100 mg/dl for not more than 2 ½ Hours.
Such simple things are not even possible at ADA and that’s why also the
Cardio-Vascular Professors complain about the ADA.
If the ADA continuously likes to have the world leading role, then they need
to do much better than that and as during the last 20 Years of watching
only how the Diabetes Epidemic got created !!
There is one more Scandal. The Surgeons at a daily base by about 60 %
occupied with Diabetics by various Bypass- or Amputation- Surgeries where
the ADA Guidelines do not help, contrary ! The ADA not commenting on this.
( Just ask the Surgery Dept. of your Hospital nearby. )
It’s now the "Personalized Care" which gets the New Slogan, but just by some
new fake fooling attempts, where by convenience the Glucose Guidance and
A1C gets increased, also to save costs. This where anybody with a little of
Diabetes Know-How knows, that the Diabetes at every Patient is individual and
different by it’s Characteristics and the Resulting Necessary Medications and
Doses, where the Diabetes Experts need to show much better considerations
and efforts at every Patient, instead complaining about the Patients !
It’s really disturbing of what presently is ongoing also by So-Called Studies
just to save costs !!
30. Diabetes & Potassium – Very Important For Heart & Health !
Without Potassium or Too Low, there is No Heart Beat ! ! !
-- Thiazides as commonly first-line agents for the treatment of hypertension,
have a common side effect of Lowering Potassium !!
See NIH.Gov Link https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197792/
-- Insulin Therapy when reaching Glucose of less 70 mg/dl or Hypo as usually
at Bolus-Meals Rapid-Insulin possible, as known is Lowering Potassium !!
( At lower normal A1C 5 – 5.5% naturally easier possible and some Studies
quickly formed wrong conclusions as if paradox higher A1C’s are better. )
-- It is very important to maintain and preserve the Normal Potassium Level
of 3.6 – 5.2 mmol/L, but at Diabetics for safety 4.2 – 5.2 mmol/L as in the
upper halve for some reserves and to ensure that the Potassium Storage is
full as necessary. The Potassium Blood Test does not show Total-Potassium
stored in the body as necessary.
See Mayo Clinic Link https://www.mayoclinic.org/symptoms/low-potassium/basics/definition/sym-20050632
-- Diabetics should monthly test the Potassium Level ! If the body temperature
has not the normally 36.5°C but only 35.5°C it could be caused by the Potassium
Level too low to aware and/or the Thyroid function also to check.
-- Diabetics to maintain the Potassium Level and to make sure, should daily eat
2 Bananas ( Middle Size Banana 400 mg Potassium ) or take daily one Novartis
Slow-K® 600 mg Potassium Tablet together with normal Meals containing Vegetables.
( If experience some Hypo by the Rapid-Insulin of 60 mg/dl take immediately 1 Slow-K Tablet
extra and if even of 50 mg/dl take immediately 2 Slow-K Tablets extra combined with the
usual Sugar amounts to increase the Glucose ! )
-- Metformin User should daily also take 30 mcg Vitamin-B12, because as known
Metformin is reducing B12 and that is also essential for the Body and Heart.
-- Maybe daily also GLP-1 Hormone injection for the Heart would possibly be
a good matter to discuss with the Doctor in Diabetology – Endocrinology.
( This since Diabetics often apply some diets with reduced Potassium, GLP-1 and
Vitamin-B12 resulting. )
About the Potassium function. Potassium can be quickly released combined with
Adrenalin at Alarming condition, but the storage is a slow process. This can been
seen at any Extreme Hypo caused by wrong measurement where Rapid-Insulin got
injected for Glucose 300 mg/dl instead some Sugar taken at effectively 55 mg/dl.
When the Insulin-Effect kicks in it’s already too late and the body get flushed
by Adrenalin and Potassium with as result only 10 minutes later additionally
a Potassium-Hypo gets created, by the Blood Pressure and Heart Pulse goes
drastically down and the body temperature also, difficult to remain conscious.
In such a situation before falling in a KOMA, only 911 Ambulance can help
because Sugar not really functioning just reducing the KOMA-Risk and they
will quickly give some intravenous Potassium to transport into the Intensive
Care Hospital for there to receive 24 Hours Potassium Infusion to restore
the Bodies Potassium Storage !
It’s possible as by above example, where until The Incident over 6 years
long the Doctors and Prof’s in Diabetology – Endocrinology mentioned
about anything as Glucose mg/dl, A1C %, Metformin and Insulins, Hypos or
Hypers, Meals, CGM, but never mentioned anything about the for the Body
most important Potassium. Potassium has also metabolism harmonizing and
regulating abilities to reduce the Average Glucose without creating Hypos !!
The Potassium is very effective, but tricky or sneaky and can over years be
on the lower Level if not checked frequently or Supplemented and by that
affecting the Left-Side of the Heart-Muscle which is responsible to pump back
the Blood out of the Veins into the Right-Side of the Heart-Muscle which is
pumping the Blood into the Arteries to start the circulation-cycle all over.
Under this conditions the Left-Side Heart-Muscle chronically becomes weaker
by lack of Potassium the Diastole-Blood-Pressure increasing, where the Right-Side
Heart-Muscle is trying to compensate this for some time, but under that double
work where the Right-Side has to pump against a higher resistance the Systole-
Blood-Pressure as result is increasing and the Right-Side-Heart-Muscle becomes
also chronically weaker until collapses and this beside of Too High Glucose of
above Average 105mg/dl causing Micro-Macro-Vascular Problems by the Blood
not able to flow freely and so also causing resistance able to see by Feet
start to get swollen, finally also by Too Low Potassium Level Is Too Much !
( Two Factors For Swollen Feet. )
When the Left-Side-Heart-Muscle is under the conditions to become weak, it can
be seen by the Feet starting to get swollen, because the Left-Side-Heart-Muscle
not pumping enough to reduce pressure and that is the last moment to counter
act by supplementing Potassium and applying monthly Potassium-Checks !!
Just the minimum of the Normal Potassium Level is also not enough to know.
Have also a look at initial Topic No. 1 and 17 with important Potassium info !!
Here is well explained how to avoid Diabetic Heart Problems.
( The ADA about all of this so important also not mentioning anything !! )
( As seen in the publications, the international Nutrition-Scientists agree that an Adult
Human from its daily Food Intake should have Daily 4000 mg Potassium, but strongly
assume that this usually not achieved and therefore a complex Study will be made. )
31. ADA & Co. Keeps You Sick By Its Hugh Conflicts of Interests !!
They get annually $ 150 - 200 Millions Donations & Sponsors Money from
the Health Insurances, Pharma-Industries, Etc., they don’t like to mess-up !
That’s the Reason why they have so Poor Guidance’s & Standards
for Type 1, Type 2, Etc. Diabetes and No Guidance’s for Prevention
or the well proven Reversal of Type 2 Diabetes.
For example worldwide are about 10,000 People which already proved
to Reverse Type 2 Diabetes, but the ADA & Co. is just ignoring this
Reality Facts and informing about Chronic Progressive Disease.
The ADA & Co. like this not able to handle the worldwide increasing
Diabetes Epidemic which resulting during the last 20 Years created !
The ADA claims that since 1952 they supported over 4700 Studies
or Clinical Trials, but at basic ADA Guidance’s or Standards noting
has changed or improved within the last 20 Years !
ADA never paid for any FDA 3 Phases Clinical Trial Costs of about
$ 50 - 100 Millions.
In 2016, the ADA’s total Revenue was $ 171 Million !
See here: https://en.wikipedia.org/wiki/American_Diabetes_Association
The ADA since 1952 by 19% of Revenues or $ 807.4 Million supported diabetes
related projects & research from its Total Revenues of $ 4.25 Billion at hands !!
Here some examples of Type 2 Reversals:
Reversal of Type 2 Diabetes to normal metabolic control by either Bariatric
Surgery and/or Hypocaloric-Diet or Low-Carb-Diet combined with Exercises.
See at following Topic 32.
32. Type 2 Diabetes Can Be Reversed !
Reversal of Type 2 Diabetes to normal metabolic control by either Bariatric
Surgery and/or Hypocaloric Diet or Low-Carb-Diet allows for the time
sequence of underlying pathophysiologic mechanisms to be observed.
It is a fact that Type 2 can be reversed as long as not any resulting
permanent disorders exist and the pancreas function is not reduced.
In Europe about 10,000 Type 2 Diabetics have been reversed !
This naturally not by OB body weight of for example 300 lbs.
Prof. Dr. Taylor in the UK giving classes and symposiums to Doctors
in Diabetology to be able to do the same.
See the links:
http://ncl.ac.uk/magres/research/diabetes/reversal/#publicinformation
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609491/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168743/
https://paleodiabetic.com/2014/01/25/dr-roy-taylor-on-the-cause-of-type-2-diabetes-and-what-to-do-about-it/
http://care.diabetesjournals.org/content/36/4/1047.full?sid=abfe05d0-e52c-4d6d-b356-4c794f9d5f69
33. HbA1c - A1C Diabetes And Cognitive Decline !
See Here https://www.ncbi.nlm.nih.gov/pubmed/29368156
The English 10 years study the ADA would not like. Because contrary to it’s
strategy to even generally increasing the A1C’s as convenience for patients-,
doctors- and health insurances for with reduced live span to save healthcare
costs and by increased A1C’s the pre-diabetic and diabetic numbers in the
epidemiology looks also much better.
As reminder, any normal healthy A1C is at about 5 % since 40 years.
34. DK Approved Individual Intensive Quality Care As Less Costly & More Healthy !
Short Version: http://cel.webofknowledge.com/InboundService.do?customersID=Highwire&smartRedirect=yes&mode=FullRecord&IsProductCode=Yes&product=CEL&Init=Yes&Func=Frame&action=retrieve&SrcApp=Highwire&SrcAuth=Highwire&SID=8EKx1YlXitBzlL8a1GV&UT=WOS%3A000180643800003
Full Report: https://www.nejm.org/doi/full/10.1056/NEJMoa0706245
Congratulation DK, you approved of what US ADA with its NIDDK or APA could not do !
35. Pre-Diabetes or Diabetes or Diabetic ?
We living in a world where mentioning the existence of declared Pre-Diabetes
according of ADA with its NIDDK is effectively already a big commitment !
In reality this only confirms the medical stupidity at highest level and is just to
help the Health Insurances to pay too late and helps all the Pharmaceutical
Industries to get More Higher Sick Peoples with higher medical demands.
It’s the Health Insurances and Pharmaceutical Industries worldwide who to ADA
provide monthly over $ 20 Million Donations- and Sponsors- Money, to know.
Diabetes Mellitus as known, if the pre-conditions exists, is a gradually developing
Disease where the various stages are individually by its intensities with the end
stage by death.
For example at Type 2 to reach the higher Diabetes Mellitus Intensity can take
Years where at Type 1 it can take Only Months.
All international Scientists agree that DM Therapies should start as early as
possible to have the chance to keep the disease at lower intensity or may
even from initially getting reversed to zero as by T2D easy possible.
The Scientists also confirmed that intensive precaution medicine is cheaper than
the present intervention medicine usually applied, because further affections or
additional costly diseases get much reduced and the living qualities improved.
Taking all above under physically or medically objective considerations, it means
there is only One-Classification existing by Diabetic in individual intensities and
characteristics, resulting to individualized intense therapies.
Resulting Objective Diagnosis of DM as Diabetic :
-- Morning Fasting Glucose 100 mg/dl or higher as Diabetic.
-- A1C of 5.3 % or higher as Diabetic. ( The A1C Test is principally a good test, but it
has problems of accuracy where the results from Lab to Lab can vary by up-to 15 %.
There is a technical equipments calibration problem since any Glycated Calibrated
Blood not exists by the nature and resulting they only trying to simulate this.
We know a Gov. Lab with Results- of +6 % and some good Private Lab. with +11 % !
-- Glucose Tolerance Test at oral 75 g by after 2 hours 180 mg/dl or higher as Diabetic.
At Diabetic the Individual Therapies and Measurements need to be decided by the
Doctors together with the Patients; without any interference from Health Insurances.
The A1C of less 5.3 % as of any healthy people, is also The Goal for Diabetics !
36. Air Pollution Increases Diabetes Risks – No Surprise !
See here: https://health.usnews.com/health-care/articles/2018-06-29/even-at-safe-levels-air-pollution-may-boost-diabetes-risk
Any Substances in solid, liquid or gas forms influence the Human Metabolism by
the kind of Substances resulting positively or negatively as also under toxicities.
The Human Metabolism is a very sensitive matter where the Metabolism at some
Substances within only 0.1 mcg ( 0.1 Million of a gram ) can decide to increase
or reduce the Glycemic Values !
At several Substances the Metabolism reacts already at Substances presents and
not only by some specific Substances Concentration, therefore Save Values can’t
be made for every Substances.
( See for example Plutonium in air and soil as the known Most Toxic Substance.
Plutonium as manmade not exists naturally, where only 1 mcg ( 1 Million of a gram )
is killing people and less than 1 mcg creates many unforeseeable uncontrollable
disorders in the body up-to gene-mutations also called Cancer.
At many Satellites are long-term Plutonium-Batteries like Mini-Reactors applied
and when they become Space-Waist or get destroyed because not functioning
anymore or as instable falling to Earth, the Plutonium gets free to contaminate
the Earth by the falling rain. That’s a real Time-Bomb made by our Scientists !
The writer here by himself with a PhD in Physics. )
Our civilization sometimes doing things so clumpsy or stupidly, it’s unbelievable !!
37. So Called Diabetes Cures At YouTube From Indian Sources ?!
Personally I like the Indian Peoples; gave years ago many-times scientific
seminars there and like it’s kind of Meals and Social very much, really
and since over 40 Years partially practice Joga because its good to do.
There is nothing wrong by promoting Vegetables, Fruits or Plants where
even the well known Metformin has its origin also from a Plant not any
pharmaceutical laboratory invention or creation to know and Vegetarian
Plants Nutritions have definitely advantages for Peoples with Diabetes
based on the Lower CH ( CH = Sugar ) Contents !!
What is only very disturbing from there is its traditional Hocus-Pocus
Minded Behavior the Indians also like to Celebrate and Pray for and
talking about not only to Better Control, but even to Cure Diabetes
with that and this is totally misleading the Worlds Diabetic Population.
To keep in mind that the 1 Bn Population has also things Really not
to understand by any logics possible with Cows freely in Capitol Streets
instead just drinking its Milk if have by not really taking care of them
resulting to Skin- Bones Cows !!
There are existing a lot of different Plants in the World as the perfect
preconditions for endless YouTube presentations by the very bad English
educated presentations with Video and The Comments easy to detect !
The Vegetarian India, where they believe can treat, prevent and cure anything
by Vegetables, Fruits and Seeds as the World Capitol of Diabetes, to know !!
Lately the well known Red Kidney Beans worldwide for its taste and highest
Beans Based Protein Content of about 25 % appreciated, become also an
Indian Example to control lower Glucose and even promoted as a natural
Prevention- and Cure- of Diabetes, as again totally misleading and fooling
the Worlds Populations; by these Peoples just like to present themselves.
There are many Peoples known eating Red Beans some even on a daily
base as myself since over 15 years by daily about 80 - 100 g some nice
Meal Portion, but by any morning fasting Glucose- or daily Intermediate-
Measuring can none of any Glucose Reduction been detected, contrary
where scientifically is known that too high Meals-Protein is even increasing
the Glucose because the clever made Liver can also Protein transform
into Glucose for Storage in the Body and the over Productions just put
into the Blood Stream and this by the daily Liver Glucose Production
Capacity of staggering up-to 500 grams, as we then can see especially
by T2D Diabetics and therefore need to take Metformin, because it’s the
Metformin which as best can Control and Reduce the Liver Glucose !! !! !!
If the Indians would not Lie to the World Population, then as in my case
it would have never been possible that after over 15 years of eating Red
Beans, 4 years ago started to become an AAN-Type Diabetic by the Pancreas
30 % Less Insulin-Production with about a 30 % Insulin-Resistance combined
Resulting to about 60 % Out of Order and that’s really no fun by resulting
daily need even 3 different types of Insulin, 24H-Basal-Insulin, 3H-Rapid and
a 6H-Effect Insulin because the Beans Digestions is 5 - 6 Hours same like
at Pizzas to know well.
The above information’s by world leading Profs. Drs. in Endocrinology by
best state of the art know-how can easily as correct been reconfirmed.
If there is a Physical-Deregulation it can only by physical matters been
corrected and if there is a Mentally-Deregulation it by Placebo can be
treated to achieve the same results. T1D or T2D is Not so Mentally !!
Please reading the above carefully for not falling into the Indian Traps.
YouTube Should Keep Clean The Internet From Any Such Matters.
Lives Can Possibly Get On High Risks By Such Cheatings ! ! ! ! !
People delaying necessary real therapies or stop them by the misleading.
38. HbA1c or A1C - Big Study Confirms Its Limitations or Use !
https://www.nature.com/articles/s41598-018-29998-z
About the HbA1c or A1C in General
HbA1c or A1C as the Golden Measurement Standard to evaluate the
Glycemic- or Therapies- Conditions of Healthy- and Diabetic- People.
Sounds good, the Red-Blood-Cells life is 3 months and therefore Tests at
healthy People are usually Annually or at Diabetics every 3 Months made
to show the important Average Glucose mg/dl during the last 3 Months !
The physical theory is perfect, but the Reality by Industrial Equipment
Production Standards & Norms by Results of permitted plus/minus 15%
equal to an overall tolerances of 30% is not acceptable for any medical
applications and additionally Are No Equipment Calibration Standards
and by the Reality Nature Does Not Any Calibrated Blood Exist !!
This means an A1C by permitted 30% Tolerance could show a result
of A1C 6.5% but effectively has only Hypo-Risks 4.55% and Diabetics
may like to improve the fake 6.5% to have less 6% by diets or higher
medication and get from one Hypo to another and into CV-Complications
by the Doctors just shaking the heads and may do not know the cause !
This also where Doctors or Labs use some cheaper A1C Test Devices to
provide quickly wrong results for good impressions only, with health failures.
Not everybody using the expensive Tina-Quant System of Roche-Cobas as
the presently in the world only reliable HbA1c Measuring Equipment:
https://usdiagnostics.roche.com/en/core_laboratory/Top-reasons-for-using-the-Tina-quant-HbA1c-methodology-to-analyze-HbA1c-results.html
FDA: https://www.accessdata.fda.gov/cdrh_docs/reviews/K121291.pdf
At A1C Labs-Reports there is not mentioned by which equipment brand, type
or calibration setting the tests made, if lucky the methodology is mentioned.
WDHCO made the some Lab-Test by sending the same Blood to 5 different
Labs and got 4 different Results as following:
-- University Lab using Tina-Quant = result A1C 5.3% as min. 6% plus, because
the result should never been A1C higher 5% as from this Normal Healthy Person
where the Blood before has over 4 Months been controlled also by using Rapid-
Insulin at Meals to avoid any Glucose-Peaks to guaranty the Blood with Glucose
never Higher 100 mg/dl and where Fasting Glucose always has been 90-96 mg/dl
and this all measured by some Laboratory calibrated Glucose-Device. This to make
sure that the Blood send to the 5 Labs has No Glycemic of A1C higher 5.0% !!
( Average Glucose of 97 mg/dl = A1C 5.0 % )
The University Lab confirmed, that they made the calibration setting a little on
the plus-side to be safe, but they did not know that it’s at least 6% Plus and
to be safe its totally wrong to have results at Plus-Side where Diabetics will
try to reduce them and resulting getting into Hypo- Risks !!
The University Lab resulting did correct its Calibration Procedures to 0% Plus
as the only one of these 5 Labs using the expensive Tina-Quant Equipment !
-- Some smaller Private Lab by doctors not so recommended = result A1C 5.3%
as min. 6% plus. Luckily by the same result as at above University Lab.
-- Some Private Lab by doctors recommended = result A1C 5.6% as min. 11% plus.
-- Some Private Lab by doctors recommended = result A1C 5.8% as min. 14% plus.
-- Some Private Lab by doctors recommended = result A1C 5.7% as min. 13% plus.
( Everybody can send the same Blood to different Labs and paying for. We don’t
know if we generally can assume to have A1C Results always on the Plus-Side. )
This where any Human at Normal A1C of 5% compare to the higher A1C at 5.5-6.0%
has already the Double Heart-Failure-Risk as by NIH.Gov here proven: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911067/
By above results it’s not to wonder why some well recommended Doctors at
medical symposiums complain about the HbA1c or A1C Lab-Quality to use !!
About Diagnostic- or Therapies- Guidances or Standards
Also by this Big Study, our initial Objective Diabetes Standards & Guidelines
related to HbA1c or A1C, Etc. as correct got again reconfirmed !
39. WHO – Therapies Standards 2018 !
http://annals.org/aim/fullarticle/2698900/medicines-treatment-intensification-type-2-diabetes-type-insulin-type-1
This mainly for health professionals.
The by WDHCO at Topic 11. introduced New Anti-Hypogenic Combination Therapy is to consider !
40. Facts & Myths About Diabetes !
10 Facts by Sarah Lewis, PharmD
https://healthguides.healthgrades.com/take-charge-of-your-diabetes-treatment/10-myths-about-diabetes
10 Facts by Dr. S.K. Nagrani
https://www.maxhealthcare.in/blogs/internal-medicine/10-myths-and-facts-about-diabetes
This here by some easy understandable explanations to help.
41. Better Test For Better Prognosis & Costs Savings !
The necessary Diabetes Innovations finally in Europe made,
not in the Too Business-Greedy USA.
http://thehealthcareblog.com/
42. World New T1D-Trial Treatment !
https://www.mirror.co.uk/news/uk-news/world-first-diabetes-treatment-launched-13226132
The Europeans once more upfront and looking for 8 more Trial-Participants !!
43. Diabetic Amputations Increasing !
As a good prove of ADA & Co worldwide misleading Diabetes Guidances.
This result is worldwide and not just in the UK, but there published.
https://www.dailymail.co.uk/health/article-6158967/Diabetes-causes-120-foot-toe-amputations-WEEK-England.html
44. Pharmacists Lead Diabetes Initiatives !
It’s the only strategy to Win The War on The Diabetes Epidemic.
Under the huge conflicts of business-interests the ADA & Co Watch, as
useless did Result to the Worldwide Diabetic Epidemic TO KNOW WELL.
People go often to Pharmacies for several matters, but not so easy go
to any Doctors or Nurses they usually too late go at emergencies only.
Since the last 50 Years there is enough Diabetes-Knowledge out there just to apply
and cooperate with for Not Reinventing Wheels anymore and to use commonsense !
Any good Pharmacies have precision Scales in the shops for the customers
take the Body-Weight and they by asking for also offering to measure the
Fasting Blood Glucose by Finger Picking; this all for free to use and know.
The responsible Pharmacist at any Pharmacy has an Academic Degree and
therefore has customs to cooperate also with medical Doctors or Health
Insurances and are not only for the Customers or Prescriptions-Patients.
Good Pharmacists can have Good Things To Happen ! ! !
For this matter Diabetics, Pharmacists, Doctors to Copy the Therapy Sheet
to discuss, negotiate and do the approvals prior of any uses; as following:
General Anti-Hypogenic Diabetes Therapy
1. Metformin 500mg Tablet every 8 hours 3x daily.
( If the dose is not sufficient, then it can be increased to up to
maximum. 3x 850mg – the Daily Max Dose is 2600mg. )
The best is Metformin "Slow-Release Glucophage SR" 1000mg every 12 hours
2x daily, but the Health Insurances as more expensive may not pay for it.
( By Metformin SR or XR there is also no digesting problem to expect. )
2. Glucobay 50mg - ½ tablet every 8 hours 3x daily.
( If the effect is not enough to increase from ½ to 1 Tablet.
The Daily Max The dose of Glucobay is 300 mg and is adjusted by
the Ferment Gases-Effect intensity level not felt as disturbing !!
At HYPOGLYCEMIA to apply only Dextrose, because Normal Sugar under
Glucobay has no effect anymore. ) Health Insurances not pay for this.
3. Januvia 25mg - Take 2x a day every 12 hours 1 Tablet, or
the 50mg Tablet if the 25mg version is not sufficient for the
Better Glucose Control.
The Daily Max. Dose of Januvia is 100 mg and get adjusted to this
level if the morning Fasting-Glucose cannot be reached by 80-95 mg/dl!
Januvia as an intelligent generation of medication is only effective when the
Glucose is higher as normal and therefore Januvia itself will never cause
any Hypoglycemia and can be used with any Diabetics.
The result of any Hypo can be caused by Bolus-Insulin wrong High or wrong
set 24H Basal-Insulin. ( 24H Basal-Insulin is just Toujeo or Tresiba to know. )
Januvia works only if the pancreas is still producing its own insulin.
Health Insurances may not pay for this first-class medication.
Use all above 3 Medications to match and adjust individually at this
New Anti-Hypogenic Therapy to have healthy normal A1C of 5-5.5% !!
4. The Morning of Fasting Blood Glucose should be set to 80 - 95 mg/dl
and never be higher than 100 mg/dl !! !! !!
3 hours after meals the Blood Glucose should not exceed 100 mg/dl !! !!
( If Insulin is also applied, this in addition to all the above medications. )
For Better Blood Circulation to prevent Neuropathies, Retinopathies,
Brain- or Kidney- or Heart- Failures, Etc. as following:
5. Normal Standard Aspirin – By ½ Tablet every second or third Days only.
( As Important It Means Taking Aspiring By Always 1 or 2 Days Pause ! )
6. Natural Vitamin-E 400-800mg Capsule every day.
7. Divided Slow-Niacin Tablets ( Vit. B3 Acid ) 3x Daily 125mg every 8 hours.
8. Every Day, eating 2 Bananas ( For Daily Potassium of 900-1000mg ) to
get some better Glycemic Control and No Heart Problems.
Or use Novartis Slow-K 600mg Tablets to take by one Day 1 Tablet and the
next Day 2 Tablets for the following Day 1 Tablet ( 1-2-1-2- Tablets ), for by
this to supplement a Daily-Average of min. 900mg Potassium it needs to fight
the World Populations Deficiency of daily about 1000mg !
PS: For more details see WDHCO http://worlddiabeteshealthcareorg.business.site/
45. US Diabetics Die By No Money For Medications !
Hello ADA & Co where are you ? ? ?
Some of Many Evidences To See Here
https://www.snopes.com/fact-check/alex-smith-died-couldnt-afford-insulin/
https://www.snopes.com/fact-check/shane-patrick-boyle-died-after-starting-a-gofundme-campaign-for-insulin/
What A World We Live In !
46. Eyesight Loss or Blindness Is Preventable – We Blind To This Facts ?
Have A Very Good Look Here:
https://www.telegraph.co.uk/health-fitness/body/half-sight-loss-preventable-yet-blind-fact/
As Prevention Also Apply The Following.
For Better Blood Circulation to prevent Neuropathies, Retinopathies,
Brain- or Kidney- or Heart- Failures, Etc. as following:
1. Normal Standard Aspirin – By ½ Tablet every second or third Days only.
( As Important It Means Taking Aspiring Always by 1 or 2 Days Pause. )
2. Natural Vitamin-E 400-800mg Capsule every day.
3. Divided Slow-Niacin Tablets ( Vit. B3 Acid ) 3x Daily 125mg every 8 hours.
4. Every Day, eating 2 Bananas ( For Daily Potassium of 900-1000mg ) to
get some better Glycemic Control and No Heart Problems.
Or use Novartis Slow-K 600mg Tablets to take by one Day 1 Tablet and the
next Day 2 Tablets for the following Day 1 Tablet ( 1-2-1-2- Tablets ), for by
this to supplement a Daily-Average of min. 900mg Potassium it needs to fight
the World Populations Deficiency of daily about 1000mg !
47. Japan – Diabetes T2D Maybe 10 – 20 Years Before Identified !
https://www.medindia.net/news/diabetes-may-be-identified-more-than-20-years-before-diagnosis-182928-1.htm
( Generally More Important Completions Will Soon Follow. )
To Keep Well In Mind, The Additionally About 20 Disorders or Diseases
All Diabetics Have The Risks For, Are Principally As Initiated Caused By
Blood Circulation Disorders / Problems Established By Increased Glucose
Above The Levels Of Any Normal Healthy People ! ! !
Therefore Any Therapy Can Only Be A Good Therapy If By Its Medications
Diabetics Can Live Within The HbA1c Or A1C Of Normal Healthy People !
At Any Matters Herein Described; Before Applying Should Been Discussed With And Approved By Doctor's In Diabetology - Endocrinology !!
This Above By All Intellectual Properties Under Copyrights© Reserved For World Diabetes Health Care Org.
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