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Acusphere, Inc. (ACUS)

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Last Post: 9/7/2018 10:13:48 AM - Followers: 30 - Board type: Free - Posts Today: 0



Update 01.20.2011

Today : Friday 20 January 2012

Acusphere, Inc. (ACUS.PK) today announced that its stockholders voted to approve the proposed 1-for-10 reverse stock split of the Company's common stock at its Special Meeting of Stockholders held today. 

See post 749 for press release, also currently a sticky post.

End Update 01.20.2012



Update 12.23.2011

Proxy Notice Of Special Meeting Received via US Mail.  Posted a sticky on some highlights, I can't find a link to it on the ACUS website but one can likely find it searching the SEC, maybe?

They are asking for a 1-10 reverse stock split.  The proxy has lots of interesting stuff in it.  Maybe someone can find a link to it and post it.......

End Update 12.23.2011


Update 12.20.2011

Another Letter to the Shareholders was issued yesterday and can be read as the first sticky post.

A line from the letter is:

"We have now arrived at an important juncture, and we need your support to help effect a reverse stock split to allow the Company to finance the completion of our strategic direction."

So a reverse split may be coming.  I have lightened up on my own shares but as of now still hold some and may buy or sell more as the future unfolds.

End 12.20.2011 update.



Update 10.07.2011

Imagify was shot down by the FDA advisory panel a couple years ago ,give or take a little, I think it was 16-1, mainly because Imagify had not been tested against a placebo.  They had run trials against the "Standard Of Care," Nuke testing.

On June 8th 2011 ACUS announced that Imagify has been granted a SPA by the FDA for an addtional phase III against a placebo.

Also on June 8th  2011 ACUS announced that they hoped to complete their work to the EU for an MMA application for Imagify in the 2nd half of 2011.

You can read about these latest developments here, and I will try to figure out how to make this post a sticky.

http://investorshub.advfn.com/boards/read_msg.aspx?message_id=64007218

Since I-Hub did away with their spell checker I no longer run my posts through one, so I apoligize to those who may be offened by this fact, in advance.

End of 10.07.2011 update.



Imagify-

Description:Imagify is a cardiovascular drug for the detection of coronary artery disease, the leading cause of death in the United States & Europe.

Partnership Agreement : On October 24, 2008, Acusphere, Inc. (the "Company") announced the signing of a definitive agreement with Cephalon, Inc. ("Cephalon") to provide $20 million in upfront financing by purchasing a $15 million senior secured convertible note and by paying a $5 million upfront fee for an exclusive worldwide license to AI-525, a preclinical-stage injectable formulation of celecoxib using Acusphere's proprietary Hydrophobic Drug Delivery System (HDDS?) technology.   On July 7, 2004, Acusphere announced a $70 million partnership for European development and marketing rights to Nycomed. From this partnership, Acusphere has currently received $12 million in milestone payments. An additional $58 million in milestone payments are related to regulatory approvals and achievement of certain sales goals.

Market Potential & Competition : The potential market in the US for Imagify is estimated to be roughly $2 billion annually. It is estimated that more than 10 million procedures are done each year in the U.S. to detect coronary artery disease. The leading procedure to detect coronary heart disease is nuclear stress testing, which costs roughly double the amount to implement, takes significantly more time to administer, and is arguably more harmful to the patient/environment.

FDA response : The FDA granted ACUS an Advisory Panel Meeting for Imagify on December 10th, 2008.  The panel voted against recommendation by a vote of 16-1.  The PDUFA date is set for February 28, 2009. On this date the FDA will decide whether or not they approve of the drug.  The company is also working with Nycomed to submit its MAA filing in Europe.

AI-850-
Description: AI-850 is a Phase 1 clinical trial completed product candidate that utilizes hydrophobic drug delivery system to improve the dissolution rate of a cancer drug.
On March 31, Acusphere licensed the property rights to its Hydrophobic Drug Delivery System™ (HDDS) for oncology applications to Cephalon for $10 million. Per the last conference call, the company may choose to license out the HDDS system to other companies for other applications. (Oncology is only one of the potential applications.)

If you would like to listen to Acusphere's most current conference calls or presentations, please go to the following:
http://investor.acusphere.com/events.cfm

Current share count:

Authorized Common Stock: 250 million shares
Outstanding Common Stock: 49.51 million shares
Preferred Stock convertible to common: 25.2 million shares

Acusphere, Inc., a specialty pharmaceutical company, develops new drugs and formulations of existing drugs using its proprietary porous microparticle technology in the United States. Its porous microparticle technology enables to control the size and porosity of particles, including nanoparticles and microparticles. The company develops products in the areas of cardiology, oncology, and asthma. Its lead product candidate Imagify, a cardiovascular drug, is in Phase 3 clinical development for the detection of coronary artery disease. The company?s products also include AI-850, a Phase 1 clinical trial completed product candidate that utilizes hydrophobic drug delivery system to improve the dissolution rate of a cancer drug; AI-128, a Phase 1 clinical study completed formulation of asthma drug. Acusphere was founded in 1993 and is headquartered in Watertown, Massachusetts.

http://www.acusphere.com/

http://finance.yahoo.com/q/h?s=ACUSD.pk





 

 

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PostSubject
#973   :) Gotcha Garyst 09/07/18 10:13:48 AM
#972   zon$x 2 shares in my opinion someone is carldfw 09/07/18 10:12:05 AM
#971   I've never figured it out either. I see Garyst 09/06/18 09:32:37 PM
#970   What do you think the one share sale carldfw 09/06/18 09:28:07 PM
#969   When those 0001's take off one can make Garyst 08/22/18 01:32:35 PM
#968   I actually bought txh@e instead of txh#d Like carldfw 08/21/18 09:07:17 PM
#967   I'll have to look at it. Not too Garyst 08/13/18 09:25:15 AM
#966   Can you tell what happened with TXH#d I carldfw 08/11/18 11:10:19 PM
#965   The only true way to find out is Garyst 08/10/18 11:43:26 AM
#964   Could be a while got to get interest carldfw 08/09/18 10:03:46 PM
#963   This thing moves on air! Garyst 05/23/18 09:27:54 PM
#962   Looking good. Garyst 05/14/18 01:50:31 PM
#961   Low float money taker you buy it up Stockhunter469 05/14/18 10:55:31 AM
#960   Lets move tomorrow! Garyst 05/13/18 10:25:17 PM
#959   Agree. Every day it is insanely thin to Garyst 05/11/18 10:05:24 PM
#958   This could easy go to the sky ..just bullofthewest 05/11/18 05:26:51 PM
#957   And a seller into the 045 bid. Garyst 05/10/18 02:35:34 PM
#956   Not sure. Good money can be made if Garyst 05/10/18 11:49:14 AM
#955   Wonder what needs to be done so people bullofthewest 05/09/18 08:35:08 PM
#954   So far if you click on the 1 Garyst 05/09/18 08:26:20 PM
#953   ACUS L2: Garyst 05/09/18 01:17:23 PM
#952   What Idiot sold to the 068 bid?? Unbelievable! Garyst 05/08/18 04:02:54 PM
#951   No selling into the 068 bid. Good sign Garyst 05/08/18 03:09:11 PM
#950   Don't sell into the .068 bid guys and Garyst 05/08/18 12:51:00 PM
#949   21k to .25 now. 3 mm's bidding .05+ Garyst 05/07/18 01:36:56 PM
#948   ACUS L2: Garyst 05/07/18 10:06:17 AM
#947   Agree. Any small buying volume and we go! Garyst 05/07/18 08:42:21 AM
#946   ACUS $$$$ COULD HAVE A MASSIVE WEEK..SO THIN halbroke1 05/07/18 12:35:30 AM
#945   L2: 20k 068 Garyst 05/04/18 03:12:16 PM
#944   057 46k shares to .25 380% Garyst 05/04/18 02:32:20 PM
#943   Who has the 25k shares for sale in Garyst 05/04/18 01:37:56 PM
#942   ACUS..... Yes look at CLWT and IMTE. If Garyst 05/04/18 10:46:59 AM
#941   ACUS L2: Garyst 05/04/18 10:41:29 AM
#940   Low floats move so fast I bought 1000 lowfloatwayne 05/03/18 11:01:42 PM
#939   Looks worse than it is as a 4k Garyst 05/03/18 09:14:07 PM
#938   On the flip side, tomorrow we'll show a Garyst 05/03/18 04:03:31 PM
#937   Good to see the bid crept up to Garyst 05/03/18 03:28:54 PM
#936   $6 sell drops us 56%. Funny Garyst 05/03/18 01:48:12 PM
#935   2000 buy there on the ask .133 Garyst 05/03/18 11:54:16 AM
#934   Just 37k now to .25 Garyst 05/03/18 10:32:16 AM
#933   47k to .25 on L2 Garyst 05/03/18 10:16:30 AM
#932   Dam!! f we had 2 million volume like Garyst 05/02/18 10:54:04 PM
#931   This Could Easily go up like IMTE DID bullofthewest 05/02/18 10:43:03 PM
#930   Not a bad day at all. bid increased Garyst 05/02/18 08:51:18 PM
#929   Super thin to $1 recent 5 days, 400% Garyst 05/02/18 03:53:18 PM
#928   Bid uptick .055. 90k on ask is gone Garyst 05/02/18 03:50:25 PM
#927   Current L2: Garyst 05/02/18 03:49:38 PM
#926   Need some buying volume but no selling into Garyst 05/02/18 02:50:26 PM
#925   WOW ASK .1480! bullofthewest 05/02/18 12:12:36 PM
#924   That 90k popped up on the ask side Garyst 05/02/18 11:57:27 AM
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