Home > Boards > US OTC > Medical - Drugs >

Acusphere, Inc (ACUS)

Add ACUS Price Alert      Hide Sticky   Hide Intro
Search This Board: 
Last Post: 7/5/2021 6:36:13 PM - Followers: 27 - Board type: Free - Posts Today: 0

Update 01.20.2011

Today : Friday 20 January 2012

Acusphere, Inc. (ACUS.PK) today announced that its stockholders voted to approve the proposed 1-for-10 reverse stock split of the Company's common stock at its Special Meeting of Stockholders held today. 

See post 749 for press release, also currently a sticky post.

End Update 01.20.2012

Update 12.23.2011

Proxy Notice Of Special Meeting Received via US Mail.  Posted a sticky on some highlights, I can't find a link to it on the ACUS website but one can likely find it searching the SEC, maybe?

They are asking for a 1-10 reverse stock split.  The proxy has lots of interesting stuff in it.  Maybe someone can find a link to it and post it.......

End Update 12.23.2011

Update 12.20.2011

Another Letter to the Shareholders was issued yesterday and can be read as the first sticky post.

A line from the letter is:

"We have now arrived at an important juncture, and we need your support to help effect a reverse stock split to allow the Company to finance the completion of our strategic direction."

So a reverse split may be coming.  I have lightened up on my own shares but as of now still hold some and may buy or sell more as the future unfolds.

End 12.20.2011 update.

Update 10.07.2011

Imagify was shot down by the FDA advisory panel a couple years ago ,give or take a little, I think it was 16-1, mainly because Imagify had not been tested against a placebo.  They had run trials against the "Standard Of Care," Nuke testing.

On June 8th 2011 ACUS announced that Imagify has been granted a SPA by the FDA for an addtional phase III against a placebo.

Also on June 8th  2011 ACUS announced that they hoped to complete their work to the EU for an MMA application for Imagify in the 2nd half of 2011.

You can read about these latest developments here, and I will try to figure out how to make this post a sticky.


Since I-Hub did away with their spell checker I no longer run my posts through one, so I apoligize to those who may be offened by this fact, in advance.

End of 10.07.2011 update.


Description:Imagify is a cardiovascular drug for the detection of coronary artery disease, the leading cause of death in the United States & Europe.

Partnership Agreement : On October 24, 2008, Acusphere, Inc. (the "Company") announced the signing of a definitive agreement with Cephalon, Inc. ("Cephalon") to provide $20 million in upfront financing by purchasing a $15 million senior secured convertible note and by paying a $5 million upfront fee for an exclusive worldwide license to AI-525, a preclinical-stage injectable formulation of celecoxib using Acusphere's proprietary Hydrophobic Drug Delivery System (HDDS?) technology.   On July 7, 2004, Acusphere announced a $70 million partnership for European development and marketing rights to Nycomed. From this partnership, Acusphere has currently received $12 million in milestone payments. An additional $58 million in milestone payments are related to regulatory approvals and achievement of certain sales goals.

Market Potential & Competition : The potential market in the US for Imagify is estimated to be roughly $2 billion annually. It is estimated that more than 10 million procedures are done each year in the U.S. to detect coronary artery disease. The leading procedure to detect coronary heart disease is nuclear stress testing, which costs roughly double the amount to implement, takes significantly more time to administer, and is arguably more harmful to the patient/environment.

FDA response : The FDA granted ACUS an Advisory Panel Meeting for Imagify on December 10th, 2008.  The panel voted against recommendation by a vote of 16-1.  The PDUFA date is set for February 28, 2009. On this date the FDA will decide whether or not they approve of the drug.  The company is also working with Nycomed to submit its MAA filing in Europe.

Description: AI-850 is a Phase 1 clinical trial completed product candidate that utilizes hydrophobic drug delivery system to improve the dissolution rate of a cancer drug.
On March 31, Acusphere licensed the property rights to its Hydrophobic Drug Delivery System™ (HDDS) for oncology applications to Cephalon for $10 million. Per the last conference call, the company may choose to license out the HDDS system to other companies for other applications. (Oncology is only one of the potential applications.)

If you would like to listen to Acusphere's most current conference calls or presentations, please go to the following:

Current share count:

Authorized Common Stock: 250 million shares
Outstanding Common Stock: 49.51 million shares
Preferred Stock convertible to common: 25.2 million shares

Acusphere, Inc., a specialty pharmaceutical company, develops new drugs and formulations of existing drugs using its proprietary porous microparticle technology in the United States. Its porous microparticle technology enables to control the size and porosity of particles, including nanoparticles and microparticles. The company develops products in the areas of cardiology, oncology, and asthma. Its lead product candidate Imagify, a cardiovascular drug, is in Phase 3 clinical development for the detection of coronary artery disease. The company?s products also include AI-850, a Phase 1 clinical trial completed product candidate that utilizes hydrophobic drug delivery system to improve the dissolution rate of a cancer drug; AI-128, a Phase 1 clinical study completed formulation of asthma drug. Acusphere was founded in 1993 and is headquartered in Watertown, Massachusetts.





Current Price
Bid Ask Day's Range
  • 1D
  • 1M
  • 2M
  • 3M
  • 6M
  • 1Y
  • 2Y
  • 3Y
  • 5Y
#995   Using dead Delaware companies for IPO search it carldfw 07/05/21 06:36:13 PM
#994   https://youtu.be/okMuq-NSq0M lowfloatwayne 04/09/20 05:01:47 PM
#993   Strap on? Ill buy more when the lowfloatwayne 04/08/20 06:34:57 PM
#992   I figured we would have six months to lowfloatwayne 01/29/20 01:31:40 PM
#991   $ACUS: ROlllllllllingggggg... $0.05 going makinezmoney 01/29/20 12:30:49 PM
#990   This low float shell could be good just carldfw 03/29/19 06:03:02 PM
#989   Not scared shorts selling a few hundred shares carldfw 02/27/19 06:30:47 PM
#988   Perfect candidate for merger. https://www.thepharmaletter.com/article/compass-th carldfw 02/24/19 12:46:49 PM
#987   This has been groomed for success most likely lowfloatwayne 02/22/19 09:58:15 PM
#986   The last one on the list was the carldfw 02/22/19 08:07:56 AM
#985   I don't see any mention of acusphere anywhere Spike1976 02/21/19 04:40:43 PM
#984   As holders though we'd like them to stay public... Garyst 01/27/19 03:25:07 PM
#983   Why have a ct order and not jusy lowfloatwayne 01/26/19 08:21:22 PM
#982   Still holding. Garyst 01/23/19 01:51:01 PM
#981   Fda trials still going on https://pubchem.ncbi.nlm.nih.gov/compound/Perfluorobut carldfw 01/23/19 08:05:59 AM
#980   Yep. Garyst 12/19/18 09:01:48 PM
#979   Mcda? Will look into. carldfw 12/19/18 06:27:46 PM
#978   Gotcha. I got into a super low float Garyst 12/19/18 03:29:07 PM
#977   I picked up a few shares this week. carldfw 12/19/18 05:40:26 AM
#976   Did you sell and take the gain or Garyst 12/18/18 10:05:52 PM
#975   What is your opinion on Euro Tech Holdings carldfw 12/18/18 08:05:33 PM
#974   I seen somewhere after 10 years they can lowfloatwayne 10/10/18 12:04:54 PM
#973   :) Gotcha Garyst 09/07/18 10:13:48 AM
#972   zon$x 2 shares in my opinion someone is carldfw 09/07/18 10:12:05 AM
#971   I've never figured it out either. I see Garyst 09/06/18 09:32:37 PM
#970   What do you think the one share sale carldfw 09/06/18 09:28:07 PM
#969   When those 0001's take off one can make Garyst 08/22/18 01:32:35 PM
#968   I actually bought txh@e instead of txh#d Like carldfw 08/21/18 09:07:17 PM
#967   I'll have to look at it. Not too Garyst 08/13/18 09:25:15 AM
#966   Can you tell what happened with TXH#d I carldfw 08/11/18 11:10:19 PM
#965   The only true way to find out is Garyst 08/10/18 11:43:26 AM
#964   Could be a while got to get interest carldfw 08/09/18 10:03:46 PM
#963   This thing moves on air! Garyst 05/23/18 09:27:54 PM
#962   Looking good. Garyst 05/14/18 01:50:31 PM
#961   Low float money taker you buy it up Stockhunter469 05/14/18 10:55:31 AM
#960   Lets move tomorrow! Garyst 05/13/18 10:25:17 PM
#959   Agree. Every day it is insanely thin to Garyst 05/11/18 10:05:24 PM
#958   This could easy go to the sky ..just bullofthewest 05/11/18 05:26:51 PM
#957   And a seller into the 045 bid. Garyst 05/10/18 02:35:34 PM
#956   Not sure. Good money can be made if Garyst 05/10/18 11:49:14 AM
#955   Wonder what needs to be done so people bullofthewest 05/09/18 08:35:08 PM
#954   So far if you click on the 1 Garyst 05/09/18 08:26:20 PM
#953   ACUS L2: Garyst 05/09/18 01:17:23 PM
#952   What Idiot sold to the 068 bid?? Unbelievable! Garyst 05/08/18 04:02:54 PM
#951   No selling into the 068 bid. Good sign Garyst 05/08/18 03:09:11 PM
#950   Don't sell into the .068 bid guys and Garyst 05/08/18 12:51:00 PM
#949   21k to .25 now. 3 mm's bidding .05+ Garyst 05/07/18 01:36:56 PM
#948   ACUS L2: Garyst 05/07/18 10:06:17 AM
#947   Agree. Any small buying volume and we go! Garyst 05/07/18 08:42:21 AM
#946   ACUS $$$$ COULD HAVE A MASSIVE WEEK..SO THIN halbroke1 05/07/18 12:35:30 AM
Consent Preferences