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Thursday, 03/20/2014 9:35:27 AM

Thursday, March 20, 2014 9:35:27 AM

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PLPL Announces Favorable Results for Human Clinical Trial
2014-03-20 09:18 ET SEATTLE, WA(eTeligis.com)Planda Biotechnology, Inc. (OTCQB:PLPL), a producer of highly bioavailable plant extracts for industries including health, wellness, nutraceutical, and pharmaceutical, today announced favorable results from a recent human clinical trial involving a topical preparation of its Phytofare Catechin Complex. The study, which was undertaken by Prof. Banie Boneschans, North West University in Potchefstroom, South Africa, one of the leading research universities on the continent, was a double-blind study that tested the anti-aging properties of Phytofare. Specifically, the trial tested surface parameters (scaling and roughness), skin hydration, and skin elasticity.

The results, which were released to the company on March 17, stated that Phytofare yielded "statistically significant" results when compared to a baseline product.The trial involved 35 female Caucasian test subjects who applied two topical creams daily, the only difference being that one contained Phytofare, to skin patches which were tested at 14, 28, and 42 days.

The process of aging has a direct impact on the status of the skin surface. Skin imperfections, such as wrinkles and scaliness, reflect light differently than smooth, younger skin. A UVA-light camera with a black-and-white video sensor was used to photograph the skin surface and then measured the differences in texture. The study showed that the addition of Phytofare improved skin roughness by as much as 15% at 28 days, and a reduction in scaliness of the stratum corneum by 20%.Both of these measures were deemed "statistically significant" by the researcher.

In testing skin hydration, a Corneometer(R) was used to measure the change in the dielectric constant due to skin surface hydration.The study showed the Phytofare increased skin hydration by 15% at both 28 and 42 days, compared to .9% and 7.8% for the base product.The study pointed out that skin hydration improved significantly at 28 days and then maintained that level throughout the study.

The elastic properties reflect the skin's ability to return to its initial position after deformation and can be effected by chronological- and photo aging of the skin. Skin elasticity was evaluated by means of a Cutometer(R).The study showed an average improvement in skin elasticity of 1% at 42 days, though there was significant inter subject variation which rendered the results inconclusive with a recommendation for a larger sample size and longer duration for a future study.

Planda Vice President Jamen Shively commented, "This study validates the last decade of research and illustrate the benefits of enhanced bioavailability.We envision our Phytofare topical formulation serving as the backbone for a host of potential cosmetic products and look forward to sharing the results with our distribution partners as we near release of Phytofare to the market."

The company has placed an abstract of the study on its website:www.plandaibiotech.com
http://www.stockwatch.com/News/Item.aspx?bid=U-et54567527-U%3aPLPL-20140320&symbol=PLPL®ion=U

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