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Re: noretreat post# 79676

Thursday, 02/06/2014 10:08:15 AM

Thursday, February 06, 2014 10:08:15 AM

Post# of 146240
Only partly true. Scale up is a problem faced by EVERY drug company. There are many factors that are strongly affected by change in scale (for example an exothermic reaction at lab scale may require no measures at all to get rid of the excess heat generated but in a 1,000 liter biofermentation vessel may require extensive measures to remove heat).

BUT there are some unusual considerations that apply to NNVC"s scaleup so you do have a point. Their products are micelles which have inherently far more variability than almost all other biotech products and scale up can have effects on that.

BUT it's also true that many, possibly most, biotechs have some similarly unusual problem that they have to deal with at some point.

There IS an usual ("unique'is an overstatement: other companies use micelles as well) aspect to NNVC's scale up but having some unusual characteristic is far more the norm than the exception.
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