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Re: None

Wednesday, 08/14/2013 5:10:12 PM

Wednesday, August 14, 2013 5:10:12 PM

Post# of 345970
Sunstar, could bavi actually...

help pd-1, etc lessen its effect on the number of T-cells activated? I do recall some deaths reported due to over stimulation in its trials.

I think the bp's that want to compete with the pd-1, etc. downstream crowd better blink "soon".

SK described in slide 13 how adding a downstream immuno, like PD-1, combines synergistically with bavi to further increase cytotoxic T-cells and also maintain their cytotoxic response to the tumor cells. These extra T-cells produce even more PS targets for bavi on the tumor cells. Showing this process now tells us that they have done the study already and learned the results.



Thanks for any thoughts.

Imo.

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