Wednesday, August 07, 2013 11:15:47 AM
http://annals.org/article.aspx?articleID=1722525
Influenza A(H7N9): From Anxiety to Preparedness
...In some critical areas, we remain at risk. Antiviral agents are potentially life-saving tools. Many developed countries have substantial stockpiles of oseltamivir. Most isolates tested to date have been reported to be sensitive to both oseltamivir and zanamivir, but 1 isolate, A/Shanghai/1/2013, contains the R294K mutation in neuraminidase that can confer oseltamivir resistance (9). Emergence of resistance to oseltamivir would greatly limit treatment options, especially for more severely ill patients. Zanamivir is likely to remain an active option, but supplies are limited and the inhaled powder formulation restricts use in some populations...
...It remains uncertain whether influenza A(H7N9) will remain a sporadic zoonosis restricted to East Asia, become a global pandemic, or become something in between. We must maintain a high level of alert and preparedness. We should redouble efforts to fill gaps in our knowledge and toolbox for response and treatment. If, as we hope, this is not the beginning of a pandemic, these efforts will still reduce the annual toll of influenza cases and help prepare for the inevitable but unpredictable appearance of the next pandemic.
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