Wednesday, June 26, 2013 7:45:51 AM
By RTT News, June 26, 2013, 07:31:00 AM EDT
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(RTTNews.com) - Medivation, Inc. ( MDVN ), pursuant to its agreement with Astellas Pharma Inc.(ALPMF.PK, ALPMY.PK), Wednesday announced enrollment of the first patient in a global Phase 2 clinical trial evaluating enzalutamide as a single agent for the treatment of advanced, androgen receptor (AR)-positive, triple-negative breast cancer or TNBC. TNBC is a type of cancer which does not express any of the three most commonly targeted receptors in breast cancer; estrogen, progesterone and HER2.
Medivation added that there would be about 80 patients with AR-positive, TNBC enrolled for the trial, and each one of them will receive enzalutamide(an androgen receptor inhibitor) at a dose of 160 mg to be taken orally once daily. The primary endpoint of the trial is clinical benefit rate, defined as the proportion of patients with a best response of complete response, partial response or stable disease for 16 weeks or more than that, Medivation said.
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This article appears in: News Headlines
Referenced Stocks: MDVN
Read more: http://www.nasdaq.com/article/medivation-astellas-begin-mid-stage-study-of-enzalutamide---quick-facts-20130626-00173#ixzz2XK13st4c
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