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Re: DewDiligence post# 2419

Thursday, 05/26/2011 3:45:49 PM

Thursday, May 26, 2011 3:45:49 PM

Post# of 2446
Re: FWIW (ART bioresorbable DES)

ABT's ABSORB BVS has anecdotal reports of cracking. Perhaps there is a demand for ART's technology if indeed this is a problem and they have solved it. Fully absorbable stents are likely less deliverable due to necessarily thicker struts, however. Probably best suited for disease that is not complex.

Micell's MiStent DES (bioabsorbable polymer over Co/Cr platform) appears to have a high probablilty of clinical success and sizable market penetration, IMHO. It may have some important advantages over JNJ’s Nevo and BSX’s Synergy -such as more rapid biodegradation- decreasing the length of required DAPT.

In any event, the case for biodegradable polymer coatings is bearing out some truth:

http://www.medicalnewstoday.com/releases/226624.php

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