GenoMed Inc. (GMED)

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GenoMed’s Observation of Major Racial Difference in Prostate Cancer Confirmed

July 16th, 2009 by towardfivequot
GenoMed Inc announced today that it has received independent confirmation of an observation the Company orignally made in 2002 that prostate cancer behaves differently in ashen and black men. In black men, angiotensin II promotes prostate cancer, and ACE inhibitors are heedful. But in unblemished men, angiotensin II protects against prostate cancer, and ACE inhibitors promote prostate cancer.

In 2002, GenoMed published a surprising be produced end: that vim of angiotensin I-converting enzyme was positively associated with prostate cancer and PSA levels in African American men, but inversely associated with prostate cancer and PSA levels in Caucasians (Moskowitz DW. Is angiotensin I-converting enzyme a “master” affliction gene? Diabetes Technol Ther. 2002;4(5):683-711. Submit 9, p. 697; PDF put available at: http://www.genomed.com/pdf/is.angiotensin.pdf). This was the first suggestion that ACE inhibitors, which block the building of angiotensin II, might protect atrocious men against prostate cancer, but espouse prostate cancer in white men.

This observation was confirmed in a subsequent paper published by GenoMed last summer (Moskowitz DW, Johnson FE. The central task of angiotensin I-converting enzyme in vertebrate pathophysiology. Curr Unequalled Med Chem. 2004;4(13):1433-54), in which ACE inhibitors were found to increase the odds of prostate cancer in a predominantly white masculine veteran hospital population by a factor of 4.7 (Table 3). A “wiring diagram” fitting for prostate cancer in white men was proposed (Figure 12, p. 1446; PDF put within reach at: genomed.com/pdf/ACE_vertebrate_pathophysiology.pdf).

GenoMed’s surprising result was confirmed by Professor Marek Pawlikowski and his put together at the University of Lodz in Poland in move up published in late 2004, which GenoMed recently became aware of(medscimonit.com/pub/vol_10/no_11/4168.pdf).

Said Dr. David Moskowitz, GenoMed’s CEO and Chief Medical Policewoman, “Dr. Pawlikowski’s bracket acclimatized a prostate cancer cell line, DU-145, that was derived from a Caucasian male. They found in vitro exactly what we found in vivo using genomic epidemiologic and pharmacoepidemiologic facts in human compliant populations: angiotensin II surprisingly inhibited the growth of the Caucasian man’s prostate cancer cells. The legend probe whim be to look at if they observe the opposite result with the CRL-2422 prostate cancer chamber belt, which is derived from an African American patient. Our data predict that ACE inhibitors see fit slow the progress of the CRL-2422 prostate cancer cells, and angiotensin II command promote it, which is what angiotensin II does to most cancer lines.”

Added Dr. Moskowitz, “The public health message is actually undisputed: every white man on an ACE inhibitor should be more closely monitored for prostate cancer with a PSA be open every 6-9 months. On the other transfer manacles, every black gink with prostate cancer should consider taking an ACE inhibitor to slow down growth of the tumor.”

About GenoMed

GenoMed, Inc. is a Next Generation DM(TM) company whose mission is to improve patient outcomes by identifying the molecular pathways that cause murrain. A St. Louis Business Journal article (http://www.stlouis.bizjournals.com/stlouis/stories/2002/05/13/story8.html) first reported that the company applied for patents based on its finding that the ACE gene is associated with many garden-variety diseases. The assemblage is currently marketing its protocols on the side of preventing kidney incompetent due to diabetes and consequential blood pressure, and delaying the progression of emphysema. The company is also conducting free clinical trials repayment for all cancers except prostate cancer in white men, as well as all viral diseases except herpes viruses. To enroll in GenoMed’s at large clinical burr under the saddle for West Nile virus, artlessly click on the West Nile virus together at http://www.genomed.com

Repository Harbor Affirmation

This press release contains forward looking statements, including those statements pertaining to GenoMed, Inc.’s (the Company’s) treatments. The words or phrases “ought to,” “should,” “may,” or be like expressions are intended to identify “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Actual results could fall out materially from those projected in the dispatch looking statements as a denouement develop of a tally of risks and uncertainties. Statements made herein are as of the date of this press release and should not be relied upon as of any subsequent date. Unless in another manner required by applicable law, we specifically disclaim any demand to update any forward-looking statements to demonstrate occurrences, developments, unanticipated events or circumstances after the antiquated of such statement.

Contact:
David Moskowitz MD FACP
GenoMed, Inc.
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genomed.com