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Friday, 01/30/2009 8:30:22 AM

Friday, January 30, 2009 8:30:22 AM

Post# of 58465
On January 14, 2009, Genta Incorporated, (the Company), announced it has initiated a new clinical trial with tesetaxel, the latest addition to Genta's oncology product portfolio. Unlike standard taxanes such as paclitaxel (Taxol�), which must be infused intravenously, tesetaxel is administered by mouth as a capsule. The new study will examine the clinical pharmacology of the drug over a narrow dosing range around the established Phase 2 dose. As a late Phase 2 agent, the Company believes tesetaxel is the leading oral taxane currently in clinical development.

http://biz.yahoo.com/e/090114/gnta.ob8-k.html



taxanes

Taxanes have been used to produce various chemotherapy drugs.

taxanes are essentially mitotic inhibitors ( stopping mitosis of the cancer cells stops their growth )

second line in block graph:

Taxanes (Docetaxel, Larotaxel, Ortataxel, Paclitaxel, Tesetaxel) · Epothilones (Ixabepilone)

http://en.wikipedia.org/wiki/Taxane


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