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Wednesday, 02/14/2024 4:15:20 PM

Wednesday, February 14, 2024 4:15:20 PM

Post# of 153
Eli Lilly was investigating Talampanel prior to 2010

For the treatment of epilepsy, malignant gliomas and ALS
development codes LY-300164 , LY300164
results from the trial for ALS have been found negative
Talampanel is not currently under development.
It showed effectiveness for epilepsy in clinical trials but its development was suspended due to its poor pharmacokinetic profile, namely a short terminal half-life (3 hours) that necessitated multiple doses per day.
RespireRx Pharmaceuticals $ RSPI a little unknown company KRM–II–81 has shown promising results for Epilepsy.
Has fully suppressed the epileptiform activity in the excised brain tissue from a 19-year-old patient with pharmaco-resistant epilepsy.
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