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jondoeuk

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jondoeuk

Re: jondoeuk post# 287

Tuesday, 06/20/2023 12:22:14 PM

Tuesday, June 20, 2023 12:22:14 PM

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Next into the clinic should be this https://aacrjournals.org/cancerres/article/83/8_Supplement/LB085/725614/Abstract-LB085-Antitumor-activity-of-AZD0754-a

Also, a trial testing an CLDN18.2-targted version with the same dnTGFbRII armour is planned.

The first TCR-T therapy https://clinicaltrials.gov/ct2/show/NCT05877599 that is armoured as well http://www.neogene.com/staging/wp-content/uploads/2022/04/Keystone-2022-TGFBR2-KO-TP53-R175H-TCR-poster-final-edit.pdf

They have been working on additional edits https://jitc.bmj.com/content/10/Suppl_2/A253
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