SiNtx Technologies Inc (SINT)

[boston745]

Meanwhile Silicon Nitride corrosive/wear particles dissolve releasing silicic acid and nitrogen compounds that benefit cellular activity, bone repair, and implant fusion.

The release of silicic acid and nitrogen compounds from the surface Si3N4 enhanced in vitro cellular activity. The results of this study demonstrate for the first time that the osseointegration behavior previously observed is operative with a peculiar chemistry within the human milieu. Si and N elements stimulated progenitor cell differentiation and osteoblastic activity, which ultimately resulted in accelerated bone ingrowth.

https://www.ncbi.nlm.nih.gov/m/pubmed/28963015/


Wear debris dissolves at faster rates than wear generation preventing the likelihood of negative biological reactions.

Wear debris generated from SiNx coatings was round in shape, with a mean size of 40 nm, and ranged between 10 and 500 nm. Model particles, similar in size and shape as the wear debris, were soluble in simulated body fluid. The dissolution rate was higher than the expected rate of debris generation.

http://uu.diva-portal.org/smash/record.jsf?pid=diva2%3A797505&dswid=291