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Friday, December 15, 2017 8:30:16 AM
Topical Skin Formulations for Cannabinoids.
Lexaria has formulated topical cream products as an extension of its DehydraTECH™ technology, for the delivery of cannabinoids into and through the skin which may prove to have emollient benefits desired by the topical products sector. Lexaria's president, John Docherty M.Sc., has extensive experience as a biotech company executive and researcher for skin-based delivery of therapeutics.
Multiple Lexaria formulations are scheduled to be laboratory tested for human skin absorption and penetration characteristics during January through March 2018. Testing will be completed at a third-party lab utilizing human skin tissue and the latest in vitro evaluative techniques to measure cannabidiol penetration in the skin. Lexaria expects to optimize formulation and manufacturing processes to develop superior-performing product designs that will potentially be available to licensees during 2018.
Nicotine in Edible Formats.
Lexaria has accelerated its research focus on nicotine following its recently announced nicotine patent grant and has been researching edible forms of nicotine which could use the Company's DehydraTECH TM technology. Formulations have been prepared and are currently completing quality control testing, prior to in vivo absorption and tolerability testing in animals.
A third-party Philadelphia based lab has been contracted to perform the first nicotine edible tests expected in February. In vivo testing with rats will examine two main outcomes:
1) Gastrointestinal distress. Without an enabling technology, untreated nicotine causes gastrointestinal upset and distress making nicotine edibles impractical. The DehydraTECHTM process will be evaluated for its ability to lessen gastrointestinal distress thus potentially opening the door to the creation of a new line of consumer products.
2) Absorption time and efficiency in crossing the intestinal wall and reaching the bloodstream. Earlier testing of the DehyrdaTECHTM process using cannabidiol as an active ingredient, proved reduced absorption times and enhanced intestinal permeability. It is expected that similar outcomes using nicotine may be experienced.
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