Spectrum Pharmaceutecals Inc (SPPI)

[antihama]

IASLC Atlas of EGFR Testing in Lung Cancer

EGFR testing becoming more standardized. Read (ok skimmed) through it. Some interesting stuff on EGFR mutations, TKI responsiveness to mutations (Chapter 4, Fig 1), a paragraph specifically on Exon 20 insertion mutations (p34), 2nd site mutations (so if your treating for 1 mutation, the TKI may not be totally effective), and testing for mutations (p46) such as Next Generation Sequencing (NGS) example I gave that the FDA recently approved by Foundation Medicine in post 1964.

https://www.iaslc.org/publications/iaslc-atlas-egfr-testing-lung-cancer