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Friday, 10/20/2017 6:33:35 AM

Friday, October 20, 2017 6:33:35 AM

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yest NEJM had 2 articles and an editorial about therapy for psoriatic arthritis, discussing the place that JAK inhibitors may play, alongside the biologics and traditional therapies, which incl apremilast of course

recall that IP has never said a word about arthritis role for P

Big picture as you know is 2-4% of world's population with psoriasis and about 30% of those have arthritis

IL20 gets no mention as a target- we have discussed recently that while PRINS and IL 20 are listed by the company as means of action when in fact IL 20 likely has nothing to do with it. Never one word about arthritis for P that I can recall.

Is this a big deal? sure it'd be nice

but at least it may play a role in therapy for most of those with psoriasis who do not after all have joint involvement
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