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Tuesday, September 19, 2017 6:15:46 PM
There is SOME unique credibility here that is often overlooked
by the scientific community and the public
This evidence,
Excerpt from the Jefferies slide
June 2017:
"PATIENT EVENTS: THERAPEUTIC RESPONSE UNEXPECTED
101001 MORE ALERT REGARDING SURROUNDINGS
101002 FEELS MUCH HAPPIER MAKING JOKES
101003 MUCH HAPPIER WHEN ATTENDING CLINIC APPTS AND ENJOYS MAKING JOKES
AND ENGAGES WELL IN CONVERSATION
101004 BETTER HAND COORDINATION. CALMER AND MORE COMMUNICATIVE
101006 IMPROVING MOODS. READING MORE BOOKS
101007
ABILITY TO PLAY THE PIANO AND READ MUSIC NOTES AT ABOUT 9 MONTHS
INTO TRIAL. SHE USED TO PLAY THE PIANO AT AGE 5 AND LOST HER ABILITY PREALZHEIMER
TRIAL
101010 ABLE TO FOLLOW PLOT WHEN WATCHING MOVIES WHEREAS PREVIOUSLY
COULD NOT
101010 MORE COMPASSION FOR CHILDREN
101011 WIFE THINKS PATIENT IS A BIT MORE CHEERFUL
101013 ABLE TO DO MUCH MORE HOUSEWORK THAN BEFORE
101013 MORE DRIVEN AND UPBEAT LESS ANXIOUS ACCORDING TO CARER
101014
AN INTERNATIONAL ARTIST WHO RESUMED HER PAINTING ABILITIES AND NOW
HAVING AN EXHIBITION IN NOV 2016. WRITTEN A 3 PAGE LETTER TO LONG LOST
BROTHER
101015 PLAYING MORE GOLF NOW BY HIMSELF. MORE CONFIDENT AT GOING OUT BY
HIMSELF
101017 ENJOYED HER TRIP TO BELGIUM - TALKS ABOUT SOME BITS OF HER TRIP
102001 IMPROVED ENGAGEMENT WITH FAMILY/FRIENDS/OUTSIDE WORLD
102008 IMPROVEMENT IN MOOD
102010 FEELING GREAT - IMPROVEMENT IN COGNITION AND MOOD, BALANCE AND
GAIT HAS IMPROVED
103001 PATIENT REMEMBERING SOMETHING HE WOULDN'T HAVE PREVIOUSLY
Though anecdotal,
Is becoming more and more important
Especially in the eyes of the FDA
Science and medicine have made giant leaps in the past 10-20 years
Unfortunately,
Drug, management, prevention, cure etc research haven't experienced the same exponential growth
New drugs and treatments
On average
Have been bandaids (at best) in most cases
And mostly failures altogether
https://www.bio.org/sites/default/files/Clinical%20Development%20Success%20Rates%202006-2015%20-%20BIO,%20Biomedtracker,%20Amplion%202016.pdf
But now
With breakthroughs in trial design, DNA, even Artificial Intelligence, etc...
new and exciting doors have opened
Failure can be detected and explained more rapidly and more accurately than ever before
And so can our ability to adapt
There are many instances where something good has been misinterpreted as initially bad
http://m.huffpost.com/us/entry/1137305/slideshow/200519
(Ok some if not most of these are wishy washy at best but that's part of the point)
McFarlane commented that the patients quality of life etc is more important than great data we fully understand
If quality of life improves
And no serious side effects are observed
... Should be approved ASAP
I believe many will be surprised at how quickly things can and I believe WILL change
Turning point is approaching...
All imho of course
Patience And
Perspective
$AVXL
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