Argos Therapeutics Inc fka ARGSQ

[TheShadow]

ARGS occupies a small percentage of my portfolio and I added to my position today, simply because I cannot ignore the possibilities here....

“We are encouraged by the results of this study, in which AGS-004 generated a targeted immune response against the HIV virus,” noted Charles Nicolette, PhD, Chief Scientific Officer of Argos. “This is an important first step in our goal of not only combating active HIV infection, but also of eliminating the HIV viral reservoir, which has not yet been achieved with any currently available agent or combination therapy. We are hopeful that our strategy of stimulating cells that are latently infected with the HIV virus with the latency-reversing agent vorinostat will enable AGS-004-stimulated memory / effector T-cells to identify and eliminate these latently infected cells, thus potentially eliminating the HIV viral reservoir.”

https://ih.advfn.com/p.php?pid=nmona&article=75311756

The latent viral reservoir consists of infected immune cells in which the HIV virus is dormant and therefore hidden from attack by the immune system. Largely because of the latent viral reservoir, currently available agents for the treatment of HIV, while able to limit the proliferation of the HIV virus, have not been successful in eradicating the virus and thus curing HIV. Argos is supporting an investigator-initiated clinical trial combining AGS-004 with the latency-reversing agent, vorinostat, under the direction of David Margolis, MD, Professor of Medicine, Division of Infectious Diseases, and Director of the HIV Cure Center at the University of North Carolina. The trial is designed to test the hypothesis that boosting antiviral immunity with AGS-004, an active immunotherapy that stimulates T cells to attack HIV-infected cells, combined with a latency reversing drug to expose the virus in latently infected cells to the immune system, may enable eradication of the virus.

http://ih.advfn.com/p.php?pid=nmona&article=75588487