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Monday, 08/28/2017 7:03:09 PM

Monday, August 28, 2017 7:03:09 PM

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JM Cuillerot, Aug. 31, at http://www.immuno-oncologysummit.com/Personalized-Cancer-Vaccines/


5:00 Autosynvax™ (ASV™), a Personalized Second Generation Vaccine Platform
Jean-Marie Cuillerot, M.D., CMO, Agenus
AutoSynVax™ (ASV™) vaccines contain patient-specific peptides with defined immunogenic epitopes resulting from specific mutations within a patient’s tumor, deduced using a proprietary algorithm, complexed with a recombinant HSP molecule (HSC70) and delivered with a saponin-based adjuvant. Preclinical studies demonstrate that heat shock protein-driven presentation of synthetic tumor neo-peptides evokes an anti-tumor immune response as well as lasting immune memory in murine cancer models.
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