Skye Bioscience Inc (SKYE)

[cjarmstrong]

Not the eye per se, but since chronic use of cannabis down regulates CB1 receptor activity, especially in the brain, I was wondering about the eye. The potential for tolerance had been mentioned in a few studies regarding glaucoma, but I didn't find much beyond that. I read a very small study where nine patients either inhaled cannabis or were administered oral THC, and although IOP was initially decreased it was not sustained. Nothing definitive, there's probably another study that had a positive outcome, but it warrants further research.