Interestingly, when you look back at the KM curves from the phase II trial, the greatest separation of curves between the two cohorts in rGBM occurred at around 12 months. I would bet VBLT is looking at the potential modeling of possible outcomes based on the expected 8-9 month survivorship of Avastin. My own guess would be a 2-3 month separation of the KM curves when the trial is finished.
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